产品简要
公司名称 :
Novus Biologicals
其他品牌 :
IMGENEX
产品类型 :
抗体
产品名称 :
NLRP3/NALP3 Antibody - BSA Free
目录 :
NBP2-12446
规格 :
0.2 ml (also 0.05 ml)
价格 :
449美元
克隆性 :
多克隆
宿主 :
domestic rabbit
共轭标签 :
DyLight系列染料350
克隆名称 :
5B12
反应物种 :
人类, 小鼠, 大鼠
应用 :
免疫印迹, 免疫组化, 免疫细胞化学, 免疫沉淀, 流式细胞仪, 免疫组化-石蜡切片, 免疫组化-冰冻切片
更多信息或购买 :
文章摘录数: 153
出版应用/物种/样本/稀释参考文献
  • 免疫组化-石蜡切片; 大鼠; 1:200; 图 5i
  • 免疫印迹; 大鼠; 1:1000; 图 5k
Wu M, Ma Y, Chen X, Liang N, Qu S, Chen H. Hyperuricemia causes kidney damage by promoting autophagy and NLRP3-mediated inflammation in rats with urate oxidase deficiency. Dis Model Mech. 2021;14: pubmed 出版商
  • 免疫印迹; 大鼠; 1:500; 图 7a
Liang H, Matei N, McBride D, Xu Y, Zhou Z, Tang J, et al. TGR5 activation attenuates neuroinflammation via Pellino3 inhibition of caspase-8/NLRP3 after middle cerebral artery occlusion in rats. J Neuroinflammation. 2021;18:40 pubmed 出版商
Wu M, Ding H, Tang X, Chen J, Zhang M, Yang Z, et al. Efficiency of a novel thermosensitive enema in situ hydrogel carrying Periplaneta americana extracts for the treatment of ulcerative colitis. Front Pharmacol. 2023;14:1111267 pubmed 出版商
Park E, Choi H, Truong C, Jun H. The Inhibition of Autophagy and Pyroptosis by an Ethanol Extract of Nelumbo nucifera Leaf Contributes to the Amelioration of Dexamethasone-Induced Muscle Atrophy. Nutrients. 2023;15: pubmed 出版商
Chen M, Li M, Wu L, Wang R, Long X, Zhang L, et al. Oridonin employs interleukin 1 receptor type 2 to treat noise-induced hearing loss by blocking inner ear inflammation. Biochem Pharmacol. 2023;210:115457 pubmed 出版商
Wang Y, Sadike D, Huang B, Li P, Wu Q, Jiang N, et al. Regulatory T cells alleviate myelin loss and cognitive dysfunction by regulating neuroinflammation and microglial pyroptosis via TLR4/MyD88/NF-κB pathway in LPC-induced demyelination. J Neuroinflammation. 2023;20:41 pubmed 出版商
Muela Zarzuela I, Suárez Rivero J, Gallardo Orihuela A, Wang C, Izawa K, de Gregorio Procopio M, et al. NLRP1 inflammasome modulates senescence and senescence-associated secretory phenotype. bioRxiv. 2023;: pubmed 出版商
Zhang H, Xie Z, Peng Y, Xie A, Fu C, Zheng D, et al. PARP1 promotes NLRP3 activation via blocking TFEB-mediated autophagy in rotenone-induced neurodegeneration. Ecotoxicol Environ Saf. 2023;252:114630 pubmed 出版商
Lin W, Li Z, Liang G, Zhou R, Zheng X, Tao R, et al. TNEA therapy promotes the autophagic degradation of NLRP3 inflammasome in a transgenic mouse model of Alzheimer's disease via TFEB/TFE3 activation. J Neuroinflammation. 2023;20:21 pubmed 出版商
Yue R, Li Y, Su B, Li C, Zeng R. Atorvastatin reduces contrast media-induced pyroptosis of renal tubular epithelial cells by inhibiting the TLR4/MyD88/NF-κB signaling pathway. BMC Nephrol. 2023;24:25 pubmed 出版商
Xiao Q, Kang Z, Liu C, Tang B. Panax notoginseng Saponins Attenuate Cerebral Ischemia-Reperfusion Injury via Mitophagy-Induced Inhibition of NLRP3 Inflammasome in Rats. Front Biosci (Landmark Ed). 2022;27:300 pubmed 出版商
P xe9 rez Cremades D, Bueno Bet xed C, Garc xed a Gim xe9 nez J, Iba xf1 ez Cabellos J, Pallard xf3 F, Hermenegildo C, et al. Extracellular histones trigger oxidative stress-dependent induction of the NF-kB/CAM pathway via TLR4 in endothelial cells. J Physiol Biochem. 2022;: pubmed 出版商
Lin J, Lai X, Fan X, Ye B, Zhong L, Zhang Y, et al. Oridonin Protects against Myocardial Ischemia-Reperfusion Injury by Inhibiting GSDMD-Mediated Pyroptosis. Genes (Basel). 2022;13: pubmed 出版商
Li S, Li H, Zhangdi H, Xu R, Zhang X, Liu J, et al. Hair follicle-MSC-derived small extracellular vesicles as a novel remedy for acute pancreatitis. J Control Release. 2022;352:1104-1115 pubmed 出版商
Zheng L, Xu H, Zheng F, Lai Y, Li J, Lv W, et al. Intervention time decides the status of autophagy, NLRP3 activity and apoptosis in macrophages induced by ox-LDL. Lipids Health Dis. 2022;21:107 pubmed 出版商
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Li M, Wu L, Chen M, Dong Y, Zheng L, Chen D, et al. Co-activation of Caspase-1 and Caspase-8 in CMV-induced SGN death by inflammasome-associated pyroptosis and apoptosis. Int Immunopharmacol. 2022;113:109305 pubmed 出版商
Zhou Z, Ying C, Zhou X, Shi Y, Xu J, Zhu Y, et al. Aerobic exercise training alleviates renal injury in db/db mice through inhibiting Nox4-mediated NLRP3 inflammasome activation. Exp Gerontol. 2022;168:111934 pubmed 出版商
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Wu J, Chen S, Wu P, Wang Y, Qi X, Zhang R, et al. Cathepsin B/HSP70 complex induced by Ilexsaponin I suppresses NLRP3 inflammasome activation in myocardial ischemia/reperfusion injury. Phytomedicine. 2022;105:154358 pubmed 出版商
Yoon B, Yun Y, Kim K, Kim D. Inhibition of immunoproteasome attenuates NLRP3 inflammasome formation in tumor necrosis factor α-stimulated intestinal epithelial cell. Biochem Biophys Res Commun. 2022;624:157-163 pubmed 出版商
Tabandeh M, Jozaie S, Ghotbedin Z, Gorani S. Dimethyl itaconic acid improves viability and steroidogenesis and suppresses cytokine production in LPS-treated bovine ovarian granulosa cells by regulating TLR4/nfkβ, NLRP3, JNK signaling pathways. Res Vet Sci. 2022;152:89-98 pubmed 出版商
Beltr xe1 n Garc xed a J, Osca Verdegal R, P xe9 rez Cremades D, Novella S, Hermenegildo C, Pallard xf3 F, et al. Extracellular Histones Activate Endothelial NLRP3 Inflammasome and are Associated with a Severe Sepsis Phenotype. J Inflamm Res. 2022;15:4217-4238 pubmed 出版商
Luo M, Hu Y, Lv D, Xie L, Yang S, Zuo D, et al. Recurrent Hypoglycemia Impaired Vascular Function in Advanced T2DM Rats by Inducing Pyroptosis. Oxid Med Cell Longev. 2022;2022:7812407 pubmed 出版商
Zhou L, Zhang J, Han X, Fang J, Zhou S, Lu L, et al. CysLT2R Antagonist HAMI 3379 Ameliorates Post-Stroke Depression through NLRP3 Inflammasome/Pyroptosis Pathway in Gerbils. Brain Sci. 2022;12: pubmed 出版商
Ge C, Zhao Y, Liang Y, He Y. Silencing of TLR4 Inhibits Atrial Fibrosis and Susceptibility to Atrial Fibrillation via Downregulation of NLRP3-TGF-β in Spontaneously Hypertensive Rats. Dis Markers. 2022;2022:2466150 pubmed 出版商
Xie D, Hu G, Chen C, Ahmadinejad F, Wang W, Li P, et al. Loss of sphingosine kinase 2 protects against cisplatin-induced kidney injury. Am J Physiol Renal Physiol. 2022;323:F322-F334 pubmed 出版商
Mavrogiannis E, Hagdorn Q, Bazioti V, Douwes J, van der Feen D, Oberdorf Maass S, et al. Pirfenidone ameliorates pulmonary arterial pressure and neointimal remodeling in experimental pulmonary arterial hypertension by suppressing NLRP3 inflammasome activation. Pulm Circ. 2022;12:e12101 pubmed 出版商
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Liu B, Wang D, Cao Y, Wu J, Zhou Y, Wu W, et al. MitoTEMPO protects against podocyte injury by inhibiting NLRP3 inflammasome via PINK1/Parkin pathway-mediated mitophagy. Eur J Pharmacol. 2022;929:175136 pubmed 出版商
Liu X, Fan T, Guan J, Luo A, Yu Y, Chen D, et al. Dopamine relieves inflammatory responses through the D2 receptor after electroacupuncture at ST36 in a mouse model of chronic obstructive pulmonary disease. Acupunct Med. 2022;:9645284221107684 pubmed 出版商
Saieva S, Taglialatela G. Near-infrared light reduces glia activation and modulates neuroinflammation in the brains of diet-induced obese mice. Sci Rep. 2022;12:10848 pubmed 出版商
Al Qazazi R, Lima P, Prisco S, Potus F, Dasgupta A, Chen K, et al. Macrophage-NLRP3 Activation Promotes Right Ventricle Failure in Pulmonary Arterial Hypertension. Am J Respir Crit Care Med. 2022;206:608-624 pubmed 出版商
Lian H, Fang X, Li Q, Liu S, Wei Q, Hua X, et al. NLRP3 Inflammasome-Mediated Pyroptosis Pathway Contributes to the Pathogenesis of Candida albicans Keratitis. Front Med (Lausanne). 2022;9:845129 pubmed 出版商
Wu Z, Zhou G, Wang H, Yao P. Inhibition of KIF23 Alleviates IPAH by Targeting Pyroptosis and Proliferation of PASMCs. Int J Mol Sci. 2022;23: pubmed 出版商
Fang J, Ouyang M, Qu Y, Wang M, Huang X, Lan J, et al. Advanced Glycation End Products Promote Melanogenesis by Activating NLRP3 Inflammasome in Human Dermal Fibroblasts. J Invest Dermatol. 2022;142:2591-2602.e8 pubmed 出版商
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Shiau A, Fang S, Hsu C, Chiu M, Lam C, Wu C, et al. Prothymosin α Gene Transfer Modulates Myocardial Remodeling after Ischemia-Reperfusion Injury. Acta Cardiol Sin. 2022;38:187-200 pubmed 出版商
Liu H, Wang L, Xu Q, Wang J, Zhang Y, Luo J, et al. UHRF1 shapes both the trophoblast invasion and decidual macrophage differentiation in early pregnancy. FASEB J. 2022;36:e22247 pubmed 出版商
Li Y, Shi D, Zhang H, Yao X, Ren K. Magnetic Resonance Imaging of Contrast-Induced Acute Renal Injury and Related Pathological Alterations In Vivo. Anal Cell Pathol (Amst). 2022;2022:6984200 pubmed 出版商
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Kang H, Seo E, Oh Y, Jun H. TGF-β activates NLRP3 inflammasome by an autocrine production of TGF-β in LX-2 human hepatic stellate cells. Mol Cell Biochem. 2022;477:1329-1338 pubmed 出版商
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Park M, Kim H, Shin H, Lee S, Hwang D, Lew H. Human Pluripotent Stem Cell-Derived Neural Progenitor Cells Promote Retinal Ganglion Cell Survival and Axon Recovery in an Optic Nerve Compression Animal Model. Int J Mol Sci. 2021;22: pubmed 出版商
Liu Y, Shang L, Zhou J, Pan G, Zhou F, Yang S. Emodin Attenuates LPS-Induced Acute Lung Injury by Inhibiting NLRP3 Inflammasome-Dependent Pyroptosis Signaling Pathway In vitro and In vivo. Inflammation. 2021;: pubmed 出版商
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Wu J, Raman A, Coffey N, Sheng X, Wahba J, Seasock M, et al. The key role of NLRP3 and STING in APOL1-associated podocytopathy. J Clin Invest. 2021;131: pubmed 出版商
Wei B, Gong Y, Yang H, Zhou J, Su Z, Liang Z. Role of tumor necrosis factor receptor‑associated factor 6 in pyroptosis during acute pancreatitis. Mol Med Rep. 2021;24: pubmed 出版商
Luo D, Dai W, Feng X, Ding C, Shao Q, Xiao R, et al. Suppression of lncRNA NLRP3 inhibits NLRP3-triggered inflammatory responses in early acute lung injury. Cell Death Dis. 2021;12:898 pubmed 出版商
Huang J, An Q, Ju B, Zhang J, Fan P, He L, et al. Role of vitamin D/VDR nuclear translocation in down-regulation of NF-κB/NLRP3/caspase-1 axis in lupus nephritis. Int Immunopharmacol. 2021;100:108131 pubmed 出版商
Tang B, She X, Deng C. Effect of the combination of astragaloside IV and Panax notoginseng saponins on pyroptosis and necroptosis in rat models of cerebral ischemia-reperfusion. Exp Ther Med. 2021;22:1123 pubmed 出版商
Guo S, Geng X, Lee H, Ding Y. Phenothiazine Inhibits Neuroinflammation and Inflammasome Activation Independent of Hypothermia After Ischemic Stroke. Mol Neurobiol. 2021;58:6136-6152 pubmed 出版商
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Lin X, Zhan J, Jiang J, Ren Y. Upregulation of Neuronal Cylindromatosis Expression is Essential for Electroacupuncture-Mediated Alleviation of Neuroinflammatory Injury by Regulating Microglial Polarization in Rats Subjected to Focal Cerebral Ischemia/Reperfusion. J Inflamm Res. 2021;14:2061-2078 pubmed 出版商
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Ma D, Zhang N, Zhang Y, Chen H. Salvianolic Acids for Injection alleviates cerebral ischemia/reperfusion injury by switching M1/M2 phenotypes and inhibiting NLRP3 inflammasome/pyroptosis axis in microglia in vivo and in vitro. J Ethnopharmacol. 2021;270:113776 pubmed 出版商
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Gao P, Zha Y, Gong X, Qiao F, Liu H. The role of maternal-foetal interface inflammation mediated by NLRP3 inflammasome in the pathogenesis of recurrent spontaneous abortion. Placenta. 2020;101:221-229 pubmed 出版商
Ma D, Zhang N, Zhang Y, Chen H. Kv1.3 channel blockade alleviates cerebral ischemia/reperfusion injury by reshaping M1/M2 phenotypes and compromising the activation of NLRP3 inflammasome in microglia. Exp Neurol. 2020;332:113399 pubmed 出版商
Yang M, So K, Lo A, Lam W. The Effect of Lycium barbarum Polysaccharides on Pyroptosis-Associated Amyloid β1-40 Oligomers-Induced Adult Retinal Pigment Epithelium 19 Cell Damage. Int J Mol Sci. 2020;21: pubmed 出版商
Zhang X, Fan X, Li F, Qiu J, Zhang Y. Effects of PYRIN-containing Apaf1-like protein 1 on isoflurane-induced postoperative cognitive dysfunction in aged rats. Mol Med Rep. 2020;22:1391-1399 pubmed 出版商
Wang Y, Ji N, Gong X, Ni S, Xu L, Zhang H. Thioredoxin-1 attenuates atherosclerosis development through inhibiting NLRP3 inflammasome. Endocrine. 2020;70:65-70 pubmed 出版商
Tang B, Liu D, Chen L, Liu Y. NLRP3 inflammasome inhibitor MCC950 attenuates primary dysmenorrhea in mice via the NF-κB/COX-2/PG pathway. J Inflamm (Lond). 2020;17:22 pubmed 出版商
Zhou X, Liu Z, Ying K, Wang H, Liu P, Ji X, et al. WJ-39, an Aldose Reductase Inhibitor, Ameliorates Renal Lesions in Diabetic Nephropathy by Activating Nrf2 Signaling. Oxid Med Cell Longev. 2020;2020:7950457 pubmed 出版商
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Chen R, Yin C, Hu Q, Liu B, Tai Y, Zheng X, et al. Expression profiling of spinal cord dorsal horn in a rat model of complex regional pain syndrome type-I uncovers potential mechanisms mediating pain and neuroinflammation responses. J Neuroinflammation. 2020;17:162 pubmed 出版商
Lalitha N, Sadashivaiah B, Ramaprasad T, Singh S. Anti-hyperglycemic activity of myricetin, through inhibition of DPP-4 and enhanced GLP-1 levels, is attenuated by co-ingestion with lectin-rich protein. PLoS ONE. 2020;15:e0231543 pubmed 出版商
Yadav S, Kambis T, Kar S, Park S, Mishra P. MMP9 mediates acute hyperglycemia-induced human cardiac stem cell death by upregulating apoptosis and pyroptosis in vitro. Cell Death Dis. 2020;11:186 pubmed 出版商
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Thakur V, Sadanandan J, Chattopadhyay M. High-Mobility Group Box 1 Protein Signaling in Painful Diabetic Neuropathy. Int J Mol Sci. 2020;21: pubmed 出版商
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Wei H, Bu R, Yang Q, Jia J, Li T, Wang Q, et al. Exendin-4 Protects against Hyperglycemia-Induced Cardiomyocyte Pyroptosis via the AMPK-TXNIP Pathway. J Diabetes Res. 2019;2019:8905917 pubmed 出版商
Nie S, Wang X, Wang H. NLRP3 Inflammasome Mediated Interleukin-1β Production in Cancer-Associated Fibroblast Contributes to ALA-PDT for Cutaneous Squamous Cell Carcinoma. Cancer Manag Res. 2019;11:10257-10267 pubmed 出版商
Kar S, Shahshahan H, Hackfort B, Yadav S, Yadav R, Kambis T, et al. Exercise Training Promotes Cardiac Hydrogen Sulfide Biosynthesis and Mitigates Pyroptosis to Prevent High-Fat Diet-Induced Diabetic Cardiomyopathy. Antioxidants (Basel). 2019;8: pubmed 出版商
Zhang H, Gong X, Ni S, Wang Y, Zhu L, Ji N. C1q/TNF-related protein-9 attenuates atherosclerosis through AMPK-NLRP3 inflammasome singling pathway. Int Immunopharmacol. 2019;77:105934 pubmed 出版商
Chen X, Li H, Wang K, Liang X, Wang W, Hu X, et al. Aerobic Exercise Ameliorates Myocardial Inflammation, Fibrosis and Apoptosis in High-Fat-Diet Rats by Inhibiting P2X7 Purinergic Receptors. Front Physiol. 2019;10:1286 pubmed 出版商
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产品信息
品牌 :
Novus
MasterCode :
NBP2-12446
SKU号 :
NBP2-12446
产品名称 :
NLRP3/NALP3 Antibody - BSA Free
描述 :
The NLRP3/NALP3 Antibody - BSA Free from NBP2-12446 is a nbp2-12446 antibody to . This antibody reacts with alzheimers research, apoptosis, cancer, cardiovascular biology, cytokine research, immunology, inflammation, neurodegeneration, signal transduction. The NLRP3/NALP3 Antibody - BSA Free has been validated for the following applications: Q96P20.
靶标 :
NLRP3/NALP3
类别 :
一抗
单位尺寸 :
0.2 ml (also 0.05 ml)
缓冲液 :
PBS
克隆性 :
多克隆
浓度 :
1.0毫克/毫升
共轭标签 :
未共轭
宿主 :
免疫原 :
This NLRP3/NALP3 antibody was raised against a portion of amino acids 1-50 of human NLRP3/NALP3.
抗体亚型 :
IgG
纯度 :
免疫原亲和纯化
物种 :
人类, 小鼠, 大鼠
理论上的分子量 :
118 kDa
基因符号 :
NLRP3
images :
https://aeroglobalimagesprod.blob.core.windows.net/images/datasheets/NLRP3-NALP3-Antibody-Western-Blot-NBP2-12446-img0011.jpg, https://aeroglobalimagesprod.blob.core.windows.net/images/datasheets/NLRP3-NALP3-Antibody-Western-Blot-NBP2-12446-img0011.jpg, https://aeroglobalimagesprod.blob.core.windows.net/images/datasheets/NLRP3-NALP3-Antibody-Immunohistochemistry-Paraffin-NBP2-12446-img0009.jpg, https://aeroglobalimagesprod.blob.core.windows.net/images/datasheets/NLRP3-NALP3-Antibody-Immunohistochemistry-Paraffin-NBP2-12446-img0009.jpg, https://aeroglobalimagesprod.blob.core.windows.net/images/datasheets/NLRP3-NALP3-Antibody-Western-Blot-NBP2-12446-img0005.jpg, https://aeroglobalimagesprod.blob.core.windows.net/images/datasheets/NLRP3-NALP3-Antibody-Western-Blot-NBP2-12446-img0005.jpg, https://aeroglobalimagesprod.blob.core.windows.net/images/datasheets/NLRP3-NALP3-Antibody-Western-Blot-NBP2-12446-img0006.jpg, https://aeroglobalimagesprod.blob.core.windows.net/images/datasheets/NLRP3-NALP3-Antibody-Western-Blot-NBP2-12446-img0006.jpg, https://aeroglobalimagesprod.blob.core.windows.net/images/datasheets/NLRP3-NALP3-Antibody-Western-Blot-NBP2-12446-img0007.jpg, https://aeroglobalimagesprod.blob.core.windows.net/images/datasheets/NLRP3-NALP3-Antibody-Western-Blot-NBP2-12446-img0007.jpg, https://aeroglobalimagesprod.blob.core.windows.net/images/datasheets/NLRP3-NALP3-Antibody-Western-Blot-NBP2-12446-img0010.jpg, https://aeroglobalimagesprod.blob.core.windows.net/images/datasheets/NLRP3-NALP3-Antibody-Western-Blot-NBP2-12446-img0010.jpg, https://aeroglobalimagesprod.blob.core.windows.net/images/datasheets/NLRP3-NALP3-Antibody-Western-Blot-NBP2-12446-img0012.jpg, https://aeroglobalimagesprod.blob.core.windows.net/images/datasheets/NLRP3-NALP3-Antibody-Western-Blot-NBP2-12446-img0012.jpg
accessionNumbers :
Q96P20
应用 :
Western Blot, Flow Cytometry, Immunohistochemistry, Immunocytochemistry/Immunofluorescence, Immunoprecipitation, Immunohistochemistry-Paraffin, Immunohistochemistry-Frozen, Immunomicroscopy, Knockdown Validated
美元 :
449美元
别名 :
AII, AII/AVP, Angiotensin/vasopressin receptor AII/AVP-like, anti-mouse NLRP3, anti-NLRP3, AVP, C1orf7, Caterpiller protein 1.1, CLR1.1, Cold autoinflammatory syndrome 1, Cold autoinflammatory syndrome 1 protein, Cryopyrin, Familial cold autoinflammatory syndrome, FCU, Leucine-rich repeat-, and PYD-containing protein 3, Muckle-Wells syndrome, MWS, NACHT, LRR and PYD containing protein 3, NACHT, LRR and PYD domains-containing protein 3, NALP3, NLR family, pyrin domain containing 3, NLRP3, NLRP3 mouse, NLRP3 polyclonal, NLRP3 rat, Nucleotide-Binding Oligomerization Domain, Leucine Rich Repeat And Pyrin Domain Containing 3, PYPAF1, PYRIN-containing APAF1-like protein 1
储存 :
Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.
更多信息或购买 :
公司信息
Novus Biologicals
10771 E Easter Ave
Centennial, CO 80112
technical@novusbio.com
https://www.novusbio.com
1-888-506-6887 303-730-1950
公司总部: 美国
Novus Biologicals的任务是开发最先进的新产品及市场行销来加速生物科研的新发现。藉由高效率的组织分工,Novus Biologicals建立了一个将生物学术团体的成果快速商品化的平台。我们的产品除了附有详细的产品资讯外,Novus Biologicals更提供完整的技术支援及服务。利用快速有效的市场通路以便迅速提供所有的科研学者最先进的研究试剂,Novus Biologicals扮演市场上重要的角色。