产品简要
公司名称 :
Novus Biologicals
其他品牌 :
IMGENEX
产品类型 :
抗体
产品名称 :
beta Amyloid Antibody (MOAB-2) - BSA Free
目录 :
NBP2-13075
规格 :
0.1 ml (also 0.025 ml)
价格 :
449美元
克隆性 :
单克隆
宿主 :
小鼠
共轭标签 :
未共轭
克隆名称 :
MOAB-2
反应物种 :
人类, 小鼠, 大鼠
应用 :
免疫印迹, 酶联免疫吸附测定, 免疫组化, 免疫细胞化学, 免疫沉淀, 免疫组化-石蜡切片, 免疫组化-冰冻切片, 免疫组化-自由浮动切片, dot blot
更多信息或购买 :
Novus Biologicals 产品网页
文章摘录数: 55
出版应用/物种/样本/稀释参考文献
  • 免疫组化-自由浮动切片; 小鼠; 1:1000; 图 1a
Puntambekar S, Moutinho M, Lin P, Jadhav V, Tumbleson Brink D, Balaji A, et al. CX3CR1 deficiency aggravates amyloid driven neuronal pathology and cognitive decline in Alzheimer's disease. Mol Neurodegener. 2022;17:47 pubmed 出版商
Marinho D, Ferreira I, Lorenzoni R, Cardoso S, Santana I, Rego A. Reduction of class I histone deacetylases ameliorates ER-mitochondria cross-talk in Alzheimer's disease. Aging Cell. 2023;22:e13895 pubmed 出版商
Chae C, Yoon J, Lim J, Park J, Cho J, Jung Y, et al. TRIM16-mediated lysophagy suppresses high-glucose-accumulated neuronal Aβ. Autophagy. 2023;19:2752-2768 pubmed 出版商
Kim M, Kim S, Lee J, Kim J, Oh E, Kim S, et al. Lignan-Rich Sesame (Sesamum indicum L.) Cultivar Exhibits In Vitro Anti-Cholinesterase Activity, Anti-Neurotoxicity in Amyloid-β Induced SH-SY5Y Cells, and Produces an In Vivo Nootropic Effect in Scopolamine-Induced Memory Impaired Mice. Antioxidants (Basel). 2023;12: pubmed 出版商
Li J, Hu T, Zhou X, Zhang T, Guo J, Wang M, et al. The involvement of NLRP3 inflammasome in CUMS-induced AD-like pathological changes and related cognitive decline in mice. J Neuroinflammation. 2023;20:112 pubmed 出版商
Tiwari V, Singh J, Tiwari P, Chaturvedi S, Gupta S, Mishra A, et al. ACE2/ANG-(1-7)/Mas receptor axis activation prevents inflammation and improves cognitive functions in streptozotocin induced rat model of Alzheimer's disease-like phenotypes. Eur J Pharmacol. 2023;946:175623 pubmed 出版商
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Liu C, Sang Z, Pan H, Wu Q, Qiu Y, Shi J. A Novel Multifunctional 5,6-Dimethoxy-Indanone-Chalcone-Carbamate Hybrids Alleviates Cognitive Decline in Alzheimer's Disease by Dual Inhibition of Acetylcholinesterase and Inflammation. Front Aging Neurosci. 2022;14:922650 pubmed 出版商
Zhong Y, Zhang C, Wang Y, Tang C, Ren J, Wang M, et al. Multiple exposures to sevoflurane across postnatal development may cause cognitive deficits in older age. Pediatr Res. 2022;: pubmed 出版商
Chen T, Lee S, Zheng W, Hsu C, Cho K, Kuo L, et al. White matter pathology in alzheimer's transgenic mice with chronic exposure to low-level ambient fine particulate matter. Part Fibre Toxicol. 2022;19:44 pubmed 出版商
Simon M, Wang M, Ismail O, Braun M, Schindler A, Reemmer J, et al. Loss of perivascular aquaporin-4 localization impairs glymphatic exchange and promotes amyloid β plaque formation in mice. Alzheimers Res Ther. 2022;14:59 pubmed 出版商
Tao R, Wang N, Shen T, Tan Y, Ren Y, Wei W, et al. High-fidelity imaging of amyloid-beta deposits with an ultrasensitive fluorescent probe facilitates the early diagnosis and treatment of Alzheimer's Disease. Theranostics. 2022;12:2549-2559 pubmed 出版商
Wang J, Zhu X, Li Y, Zhang P, Wang T, Li M. Jiedu-Yizhi Formula Improves Cognitive Impairment in an Aβ 25-35-Induced Rat Model of Alzheimer's Disease by Inhibiting Pyroptosis. Evid Based Complement Alternat Med. 2022;2022:6091671 pubmed 出版商
Hud xe1 k A, Letoha A, Vizler C, Letoha T. Syndecan-3 as a Novel Biomarker in Alzheimer's Disease. Int J Mol Sci. 2022;23: pubmed 出版商
He Z, Huan P, Wang L, He J. Paeoniflorin ameliorates cognitive impairment in Parkinson's disease via JNK/p53 signaling. Metab Brain Dis. 2022;37:1057-1070 pubmed 出版商
Walker J, Kazempour Dehkordi S, Fracassi A, Vanschoiack A, Pavenko A, Taglialatela G, et al. Differential protein expression in the hippocampi of resilient individuals identified by digital spatial profiling. Acta Neuropathol Commun. 2022;10:23 pubmed 出版商
Zhao X, Hasan S, Liou B, Lin Y, Sun Y, Liu C. Analysis of the Biomarkers for Neurodegenerative Diseases in Aged Progranulin Deficient Mice. Int J Mol Sci. 2022;23: pubmed 出版商
Han J, Hyun J, Park J, Jung S, Oh Y, Kim Y, et al. Aberrant role of pyruvate kinase M2 in the regulation of gamma-secretase and memory deficits in Alzheimer's disease. Cell Rep. 2021;37:110102 pubmed 出版商
Rimal S, Li Y, Vartak R, Geng J, Tantray I, Li S, et al. Inefficient quality control of ribosome stalling during APP synthesis generates CAT-tailed species that precipitate hallmarks of Alzheimer's disease. Acta Neuropathol Commun. 2021;9:169 pubmed 出版商
Godoy P, Mennickent D, Cuchillo Ibanez I, Ramírez Molina O, Silva Grecchi T, Panes Fernández J, et al. Increased P2×2 receptors induced by amyloid-β peptide participates in the neurotoxicity in alzheimer's disease. Biomed Pharmacother. 2021;142:111968 pubmed 出版商
Choi C, Park J, Kim H, Chang K, Park J, MIN K. DSCR1 upregulation enhances dural meningeal lymphatic drainage to attenuate amyloid pathology of Alzheimer's disease. J Pathol. 2021;255:296-310 pubmed 出版商
Wang M, Feng L, Li Z, Ma K, Chang K, Chen X, et al. Thymosin β4 reverses phenotypic polarization of glial cells and cognitive impairment via negative regulation of NF-κB signaling axis in APP/PS1 mice. J Neuroinflammation. 2021;18:146 pubmed 出版商
Yang Y, Zhang J, Yang X, Li Z, Wang J, Lu C, et al. Dysregulated APP expression and α-secretase processing of APP is involved in manganese-induced cognitive impairment. Ecotoxicol Environ Saf. 2021;220:112365 pubmed 出版商
Souder D, Dreischmeier I, Smith A, Wright S, Martin S, Sagar M, et al. Rhesus monkeys as a translational model for late-onset Alzheimer's disease. Aging Cell. 2021;20:e13374 pubmed 出版商
Hanna R, Flamier A, Barabino A, Bernier G. G-quadruplexes originating from evolutionary conserved L1 elements interfere with neuronal gene expression in Alzheimer's disease. Nat Commun. 2021;12:1828 pubmed 出版商
Liu Y, Hanson K, McCormack G, Atkinson R, Dittmann J, Vickers J, et al. Enhanced Anti-Amyloid Effect of Combined Leptin and Pioglitazone in APP/PS1 Transgenic Mice. Curr Alzheimer Res. 2020;17:1294-1301 pubmed 出版商
Fernández Pérez E, Gallegos S, Armijo Weingart L, Araya A, Riffo Lepe N, Cayumán F, et al. Changes in neuronal excitability and synaptic transmission in nucleus accumbens in a transgenic Alzheimer's disease mouse model. Sci Rep. 2020;10:19606 pubmed 出版商
Heckmann B, Teubner B, Boada Romero E, Tummers B, Guy C, Fitzgerald P, et al. Noncanonical function of an autophagy protein prevents spontaneous Alzheimer's disease. Sci Adv. 2020;6:eabb9036 pubmed 出版商
Hernández Rodríguez M, Arciniega Martinez I, García Marín I, Correa Basurto J, Rosales Hernández M. Chronic Administration of Scopolamine Increased GSK3βP9, Beta Secretase, Amyloid Beta, and Oxidative Stress in the Hippocampus of Wistar Rats. Mol Neurobiol. 2020;57:3979-3988 pubmed 出版商
Acharya A, Stockmann J, Beyer L, Rudack T, Nabers A, GUMBART J, et al. The Effect of (-)-Epigallocatechin-3-Gallate on the Amyloid-β Secondary Structure. Biophys J. 2020;119:349-359 pubmed 出版商
Voth S, Gwin M, FRANCIS C, Balczon R, Frank D, Pittet J, et al. Virulent Pseudomonas aeruginosa infection converts antimicrobial amyloids into cytotoxic prions. FASEB J. 2020;34:9156-9179 pubmed 出版商
Liu X, Deng Y, Dai Z, Hu T, Cai W, Liu H, et al. Sodium tanshinone IIA sulfonate protects against Aβ1-42-induced cellular toxicity by modulating Aβ-degrading enzymes in HT22 cells. Int J Biol Macromol. 2020;151:47-55 pubmed 出版商
He Y, Ruganzu J, Lin C, Ding B, Zheng Q, Wu X, et al. Tanshinone IIA ameliorates cognitive deficits by inhibiting endoplasmic reticulum stress-induced apoptosis in APP/PS1 transgenic mice. Neurochem Int. 2020;133:104610 pubmed 出版商
Joseph E, Villalobos Acosta D, Torres Ramos M, Farfán García E, Gómez López M, Miliar Garcia A, et al. Neuroprotective Effects of Apocynin and Galantamine During the Chronic Administration of Scopolamine in an Alzheimer's Disease Model. J Mol Neurosci. 2020;70:180-193 pubmed 出版商
Prokop S, Miller K, Labra S, Pitkin R, Hoxha K, Narasimhan S, et al. Impact of TREM2 risk variants on brain region-specific immune activation and plaque microenvironment in Alzheimer's disease patient brain samples. Acta Neuropathol. 2019;138:613-630 pubmed 出版商
Balczon R, Pittet J, Wagener B, Moser S, Voth S, Vorhees C, et al. Infection-induced endothelial amyloids impair memory. FASEB J. 2019;33:10300-10314 pubmed 出版商
Tian C, Liu G, Gao L, Soltys D, Pan C, Stewart T, et al. Erythrocytic α-Synuclein as a potential biomarker for Parkinson's disease. Transl Neurodegener. 2019;8:15 pubmed 出版商
El Hajjar J, Chatoo W, Hanna R, Nkanza P, Tétreault N, Tse Y, et al. Heterochromatic genome instability and neurodegeneration sharing similarities with Alzheimer's disease in old Bmi1+/- mice. Sci Rep. 2019;9:594 pubmed 出版商
Cristiano C, Volpicelli F, Lippiello P, Buono B, Raucci F, Piccolo M, et al. Neutralization of interleukin-17 rescues amyloid-β-induced neuroinflammation and memory impairment. Br J Pharmacol. 2019;: pubmed 出版商
Collins J, King A, Woodhouse A, Kirkcaldie M, Vickers J. Age moderates the effects of traumatic brain injury on beta-amyloid plaque load in APP/PS1 mice. J Neurotrauma. 2019;: pubmed 出版商
Kim D, Lee D, Lim H, Choi S, Oh W, Yang Y, et al. Effect of growth differentiation factor-15 secreted by human umbilical cord blood-derived mesenchymal stem cells on amyloid beta levels in in vitro and in vivo models of Alzheimer's disease. Biochem Biophys Res Commun. 2018;504:933-940 pubmed 出版商
Woodhouse A, Fernández Martos C, Atkinson R, Hanson K, Collins J, O Mara A, et al. Repeat propofol anesthesia does not exacerbate plaque deposition or synapse loss in APP/PS1 Alzheimer's disease mice. BMC Anesthesiol. 2018;18:47 pubmed 出版商
Kim D, Lim H, Lee D, Choi S, Oh W, Yang Y, et al. Thrombospondin-1 secreted by human umbilical cord blood-derived mesenchymal stem cells rescues neurons from synaptic dysfunction in Alzheimer's disease model. Sci Rep. 2018;8:354 pubmed 出版商
Paspalas C, Carlyle B, Leslie S, Preuss T, Crimins J, Huttner A, et al. The aged rhesus macaque manifests Braak stage III/IV Alzheimer's-like pathology. Alzheimers Dement. 2018;14:680-691 pubmed 出版商
Muthukumaran K, Kanwar A, Vegh C, Marginean A, Elliott A, Guilbeault N, et al. Ubisol-Q10 (a Nanomicellar Water- Soluble Formulation of CoQ10) Treatment Inhibits Alzheimer-Type Behavioral and Pathological Symptoms in a Double Transgenic Mouse (TgAPEswe, PSEN1dE9) Model of Alzheimer's Disease. J Alzheimers Dis. 2017;: pubmed 出版商
Lee D, Hwang C, Choi J, Park M, Song M, Oh K, et al. KRICT-9 inhibits neuroinflammation, amyloidogenesis and memory loss in Alzheimer's disease models. Oncotarget. 2017;8:68654-68667 pubmed 出版商
Stuart K, King A, Fernandez Martos C, Summers M, Vickers J. Environmental novelty exacerbates stress hormones and Aβ pathology in an Alzheimer's model. Sci Rep. 2017;7:2764 pubmed 出版商
Balczon R, Morrow K, Zhou C, Edmonds B, Alexeyev M, Pittet J, et al. Pseudomonas aeruginosa infection liberates transmissible, cytotoxic prion amyloids. FASEB J. 2017;31:2785-2796 pubmed 出版商
Stuart K, King A, Fernandez Martos C, Dittmann J, Summers M, Vickers J. Mid-life environmental enrichment increases synaptic density in CA1 in a mouse model of A?-associated pathology and positively influences synaptic and cognitive health in healthy ageing. J Comp Neurol. 2017;525:1797-1810 pubmed 出版商
Yu Y, Hsieh T, Chen K, Wu J, Hoffer B, Greig N, et al. Glucose-Dependent Insulinotropic Polypeptide Ameliorates Mild Traumatic Brain Injury-Induced Cognitive and Sensorimotor Deficits and Neuroinflammation in Rats. J Neurotrauma. 2016;33:2044-2054 pubmed
Collins J, King A, Woodhouse A, Kirkcaldie M, Vickers J. The effect of focal brain injury on beta-amyloid plaque deposition, inflammation and synapses in the APP/PS1 mouse model of Alzheimer's disease. Exp Neurol. 2015;267:219-29 pubmed 出版商
Kim J, Yun H, Jin P, Lee H, Han J, Udumula V, et al. Inhibitory effect of a 2,4-bis(4-hydroxyphenyl)-2-butenal diacetate on neuro-inflammatory reactions via inhibition of STAT1 and STAT3 activation in cultured astrocytes and microglial BV-2 cells. Neuropharmacology. 2014;79:476-87 pubmed 出版商
Youmans K, Tai L, Nwabuisi Heath E, JUNGBAUER L, Kanekiyo T, Gan M, et al. APOE4-specific changes in A? accumulation in a new transgenic mouse model of Alzheimer disease. J Biol Chem. 2012;287:41774-86 pubmed 出版商
Youmans K, Tai L, Kanekiyo T, Stine W, Michon S, Nwabuisi Heath E, et al. Intraneuronal A? detection in 5xFAD mice by a new A?-specific antibody. Mol Neurodegener. 2012;7:8 pubmed 出版商
图像
图像 1 :
Novus Biologicals NBP2-13075 图像 1
Immunohistochemistry: beta Amyloid Antibody (MOAB-2) [NBP2-13075] - IHC analysis of beta Amyloid on normal mouse brain (left) and 5xFAD mouse brain (right) using DAB with hematoxylin counterstain. The MOAB-2 antibody was used at 1:20 on normal mouse brain and at 1:400 on 5xFAD mouse brain.
产品信息
品牌 :
Novus
MasterCode :
NBP2-13075
SKU号 :
NBP2-13075
产品名称 :
beta Amyloid Antibody (MOAB-2) - BSA Free
描述 :
The beta Amyloid Antibody (MOAB-2) - BSA Free from NBP2-13075 is a nbp2-13075 antibody to . This antibody reacts with alzheimers research, apoptosis, cardiovascular biology, cell cycle and replication, neurodegeneration, neuronal cell markers, neuroscience, signal transduction. The beta Amyloid Antibody (MOAB-2) - BSA Free has been validated for the following applications: P05067.
靶标 :
乙淀粉样蛋白
类别 :
一抗
单位尺寸 :
0.1 ml (also 0.025 ml)
缓冲液 :
PBS
克隆性 :
单克隆
克隆 :
MOAB-2
浓度 :
1.0毫克/毫升
共轭标签 :
未共轭
宿主 :
小鼠
免疫原 :
This beta Amyloid antibody was developed against recombinant human beta Amyloid 42.
抗体亚型 :
IgG2b
纯度 :
蛋白质G纯化
物种 :
Human, Mouse, Rat, Bacteria, Monkey
特异性 :
Beta Amyloid antibody (MOAB-2) recognizes unaggregated, oligomeric and fibrillar forms of beta Amyloid 42 and unaggregated beta Amyloid 40
理论上的分子量 :
5 kDa
基因符号 :
淀粉样蛋白前体
images :
https://aeroglobalimagesprod.blob.core.windows.net/images/datasheets/beta-Amyloid-Antibody-(MOAB-2)-Immunohistochemistry-NBP2-13075-img0014.jpg, https://aeroglobalimagesprod.blob.core.windows.net/images/datasheets/beta-Amyloid-Antibody-(MOAB-2)-Immunohistochemistry-NBP2-13075-img0014.jpg, https://aeroglobalimagesprod.blob.core.windows.net/images/datasheets/beta-Amyloid-Antibody-(MOAB-2)-Immunohistochemistry-NBP2-13075-img0014.jpg, https://aeroglobalimagesprod.blob.core.windows.net/images/datasheets/beta-Amyloid-Antibody-(MOAB-2)-Western-Blot-NBP2-13075-img0017.jpg, https://aeroglobalimagesprod.blob.core.windows.net/images/datasheets/beta-Amyloid-Antibody-(MOAB-2)-Western-Blot-NBP2-13075-img0017.jpg, https://aeroglobalimagesprod.blob.core.windows.net/images/datasheets/beta-Amyloid-Antibody-(MOAB-2)-Western-Blot-NBP2-13075-img0017.jpg, https://aeroglobalimagesprod.blob.core.windows.net/images/datasheets/beta-Amyloid-Antibody-(MOAB-2)-Western-Blot-NBP2-13075-img0016.jpg, https://aeroglobalimagesprod.blob.core.windows.net/images/datasheets/beta-Amyloid-Antibody-(MOAB-2)-Western-Blot-NBP2-13075-img0016.jpg, https://aeroglobalimagesprod.blob.core.windows.net/images/datasheets/beta-Amyloid-Antibody-(MOAB-2)-Western-Blot-NBP2-13075-img0016.jpg, https://aeroglobalimagesprod.blob.core.windows.net/images/datasheets/beta-Amyloid-Antibody-(MOAB-2)-Immunohistochemistry-Paraffin-NBP2-13075-img0015.jpg, https://aeroglobalimagesprod.blob.core.windows.net/images/datasheets/beta-Amyloid-Antibody-(MOAB-2)-Immunohistochemistry-Paraffin-NBP2-13075-img0015.jpg, https://aeroglobalimagesprod.blob.core.windows.net/images/datasheets/beta-Amyloid-Antibody-(MOAB-2)-Immunohistochemistry-Paraffin-NBP2-13075-img0015.jpg, https://aeroglobalimagesprod.blob.core.windows.net/images/datasheets/beta-Amyloid-Antibody-(MOAB-2)-Immunocytochemistry-Immunofluorescence-NBP2-13075-img0009.jpg, https://aeroglobalimagesprod.blob.core.windows.net/images/datasheets/beta-Amyloid-Antibody-(MOAB-2)-Immunocytochemistry-Immunofluorescence-NBP2-13075-img0009.jpg, https://aeroglobalimagesprod.blob.core.windows.net/images/datasheets/beta-Amyloid-Antibody-(MOAB-2)-Immunocytochemistry-Immunofluorescence-NBP2-13075-img0009.jpg, https://aeroglobalimagesprod.blob.core.windows.net/images/datasheets/beta-Amyloid-Antibody-(MOAB-2)-Immunohistochemistry-NBP2-13075-img0019.jpg, https://aeroglobalimagesprod.blob.core.windows.net/images/datasheets/beta-Amyloid-Antibody-(MOAB-2)-Immunohistochemistry-NBP2-13075-img0019.jpg, https://aeroglobalimagesprod.blob.core.windows.net/images/datasheets/beta-Amyloid-Antibody-(MOAB-2)-Immunohistochemistry-NBP2-13075-img0019.jpg, https://aeroglobalimagesprod.blob.core.windows.net/images/datasheets/beta-Amyloid-Antibody-(MOAB-2)-Immunohistochemistry-Paraffin-NBP2-13075-img0012.jpg, https://aeroglobalimagesprod.blob.core.windows.net/images/datasheets/beta-Amyloid-Antibody-(MOAB-2)-Immunohistochemistry-Paraffin-NBP2-13075-img0012.jpg, https://aeroglobalimagesprod.blob.core.windows.net/images/datasheets/beta-Amyloid-Antibody-(MOAB-2)-Immunohistochemistry-Paraffin-NBP2-13075-img0012.jpg, https://aeroglobalimagesprod.blob.core.windows.net/images/datasheets/beta-Amyloid-Antibody-(MOAB-2)-Immunohistochemistry-Frozen-NBP2-13075-img0018.jpg, https://aeroglobalimagesprod.blob.core.windows.net/images/datasheets/beta-Amyloid-Antibody-(MOAB-2)-Immunohistochemistry-Frozen-NBP2-13075-img0018.jpg, https://aeroglobalimagesprod.blob.core.windows.net/images/datasheets/beta-Amyloid-Antibody-(MOAB-2)-Immunohistochemistry-Frozen-NBP2-13075-img0018.jpg
accessionNumbers :
P05067
应用 :
Western Blot, ELISA, Immunohistochemistry, Immunocytochemistry/Immunofluorescence, Immunoprecipitation, Immunohistochemistry-Paraffin, Immunohistochemistry-Frozen, Immunoblotting, Dot Blot, Immunohistochemistry Free-Floating
美元 :
449美元
别名 :
Abeta, Amyloid beta, beta-amyloid peptide
储存 :
Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.
更多信息或购买 :
Novus Biologicals 产品网页
公司信息
Novus Biologicals
10771 E Easter Ave
Centennial, CO 80112
technical@novusbio.com
https://www.novusbio.com
1-888-506-6887 303-730-1950
公司总部: 美国
Novus Biologicals的任务是开发最先进的新产品及市场行销来加速生物科研的新发现。藉由高效率的组织分工，Novus Biologicals建立了一个将生物学术团体的成果快速商品化的平台。我们的产品除了附有详细的产品资讯外，Novus Biologicals更提供完整的技术支援及服务。利用快速有效的市场通路以便迅速提供所有的科研学者最先进的研究试剂，Novus Biologicals扮演市场上重要的角色。