产品简要
公司名称 :
Novus Biologicals
其他品牌 :
IMGENEX
产品类型 :
抗体
产品名称 :
Bcl-2 Antibody (100/D5)
目录 :
NBP2-15200
规格 :
0.02毫克
价格 :
149美元
克隆性 :
单克隆
宿主 :
小鼠
共轭标签 :
未共轭
克隆名称 :
100/D5
反应物种 :
人类, 小鼠, 大鼠
应用 :
免疫印迹, 酶联免疫吸附测定, 免疫组化, 免疫细胞化学, 免疫沉淀, 流式细胞仪, 免疫组化-石蜡切片, 免疫组化-冰冻切片
更多信息或购买 :
Novus Biologicals 产品网页
文章摘录数: 8
参考文献
Olszewska B, Zawrocki A, Lakomy J, Karczewska J, Gleń J, Zabłotna M, et al. Mapping signal transducer and activator of transcription (STAT) activity in different stages of mycosis fungoides and Sezary syndrome. Int J Dermatol. 2020;59:1106-1112 pubmed 出版商
Sławińska M, Lakomy J, Biernat W, Sokołowska Wojdyło M, Karczewska J, Zabłotna M, et al. STAT3, STAT5A, STAT5B and STAT6 proteins are overexpressed in human basal cell carcinoma. Clin Exp Dermatol. 2019;: pubmed 出版商
Mega Tiber P, Kocyigit Sevinc S, Kilinc O, Orun O. Biological effects of whole Z.Officinale extract on chronic myeloid leukemia cell line K562. Gene. 2019;692:217-222 pubmed 出版商
Pradhan N, Pratheek B, Garai A, Kumar A, Meena V, Ghosh S, et al. Induction of apoptosis by Fe(salen)Cl through caspase-dependent pathway specifically in tumor cells. Cell Biol Int. 2014;38:1118-31 pubmed 出版商
Moschovi M, Koultouki E, Stefanaki K, Sfakianos G, Tourkantoni N, Prodromou N, et al. Prognostic significance of angiogenesis in relation to Ki-67, p-53, p-27, and bcl-2 expression in embryonal tumors. Pediatr Neurosurg. 2011;47:241-7 pubmed 出版商
Tralongo V, Becchina G, Nagar C, Ottoveggio G, Mason S, Seno B, et al. Primary follicular lymphoma of the epididymis positive for t(14;18)(q32;q21)/IGH-BCL2 and negative for BCL2 protein expression: a case report. J Med Case Rep. 2012;6:24 pubmed 出版商
Kren L, Brazdil J, Hermanova M, Goncharuk V, Kallakury B, Kaur P, et al. Prognostic significance of anti-apoptosis proteins survivin and bcl-2 in non-small cell lung carcinomas: a clinicopathologic study of 102 cases. Appl Immunohistochem Mol Morphol. 2004;12:44-9 pubmed
Kaur P, Kallakury B, Sheehan C, Fisher H, Kaufman R, Ross J. Survivin and Bcl-2 expression in prostatic adenocarcinomas. Arch Pathol Lab Med. 2004;128:39-43 pubmed
图像
图像 1 :
Novus Biologicals NBP2-15200 图像 1
Western Blot: Bcl-2 Antibody (100/D5) [NBP2-15200] - Western Blot Analysis of human MCF-7 cell lysate using Bcl-2 Antibody (100/D5).
产品信息
品牌 :
Novus
master code :
NBP2-15200
SKU号 :
NBP2-15200.02毫克
产品名称 :
Bcl-2 Antibody (100/D5)
描述 :
The Bcl-2 Antibody (100/D5) from Novus Biologicals is a mouse monoclonal antibody to Bcl-2. This antibody reacts with human, mouse (negative), rat (negative). The Bcl-2 Antibody (100/D5) has been validated for the following applications: Western Blot, Flow Cytometry, ELISA, Immunohistochemistry, Immunocytochemistry/Immunofluorescence, Immunoprecipitation, Immunohistochemistry-Paraffin, Immunohistochemistry-Frozen, Flow (Intracellular).
靶标 :
Bcl-2
类别 :
一抗
单位尺寸 :
0.02毫克
缓冲液 :
10 mM PBS with 0.05% BSA
克隆性 :
单克隆
克隆 :
100/D5
浓度 :
0.2毫克/毫升
共轭标签 :
未共轭
宿主 :
小鼠
免疫原 :
The synthetic peptide corresponding to amino acids range from 41-64 (GAAPAPGIFSSQPG-Cys), of human Bcl-2 was used as immunogen to generate the antibody; GenBank no. NP_000648.2 (Pezzella et al, 1990).
抗体亚型 :
IgG1 Kappa
纯度 :
蛋白质G纯化
物种 :
Human, Mouse (Negative), Rat (Negative)
特异性 :
This antibody recognizes a protein of 25-26kDa, identified as the bcl-2alpha oncoprotein. It shows no cross-reaction with Bcl-x or Bax protein. Expression of bcl-2alpha oncoprotein inhibits the programmed cell death (apoptosis). In most follicular lymphomas, neoplastic germinal centers express high levels of bcl-2alpha protein, whereas the normal or hyperplastic germinal centers are negative. Consequently, this antibody is valuable when distinguishing between reactive and neoplastic follicular proliferation in lymph node biopsies. It may also be used in distinguishing between those follicular lymphomas that express bcl-2 protein and the small number in which the neoplastic cells are bcl-2 negative.
理论上的分子量 :
25 kDa
基因符号 :
BCL2
catalog number base :
NBP2-15200
accessionNumbers :
P10415
应用 :
Western Blot, Flow Cytometry, ELISA, Immunohistochemistry, Immunocytochemistry/Immunofluorescence, Immunoprecipitation, Immunohistochemistry-Paraffin, Immunohistochemistry-Frozen, Flow (Intracellular)
2020美元 :
129
2021美元 :
149美元
别名 :
apoptosis regulator Bcl-2, B-cell CLL/lymphoma 2, Bcl-2
储存 :
存放在4C
更多信息或购买 :
Novus Biologicals 产品网页
公司信息
Novus Biologicals
8100 Southpark Way, A-8
Littleton, CO 80120
technical@novusbio.com
https://www.novusbio.com
1-888-506-6887 303-730-1950
公司总部: 美国
Novus Biologicals的任务是开发最先进的新产品及市场行销来加速生物科研的新发现。藉由高效率的组织分工，Novus Biologicals建立了一个将生物学术团体的成果快速商品化的平台。我们的产品除了附有详细的产品资讯外，Novus Biologicals更提供完整的技术支援及服务。利用快速有效的市场通路以便迅速提供所有的科研学者最先进的研究试剂，Novus Biologicals扮演市场上重要的角色。