This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.
产品简要
公司名称 :
Novus Biologicals
其他品牌 :
IMGENEX
产品类型 :
抗体
产品名称 :
p62/泛肽结合蛋白p62抗体(5H7E2)
目录 :
NBP2-23490
规格 :
0.1 ml (also 0.025 ml)
价格 :
283美元
克隆性 :
单克隆
宿主 :
小鼠
共轭标签 :
未共轭
克隆名称 :
5H7E2
反应物种 :
人类
应用 :
免疫印迹, 酶联免疫吸附测定, 免疫组化, 免疫细胞化学, 流式细胞仪, 免疫组化-石蜡切片
文章摘录数: 49
出版应用/物种/样本/稀释参考文献
  • 免疫印迹; 人类; 图 7b
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Trejo Lopez J, Sorrentino Z, Riffe C, Prokop S, Dickson D, Yachnis A, et al. Generation and Characterization of Novel Monoclonal Antibodies Targeting p62/sequestosome-1 Across Human Neurodegenerative Diseases. J Neuropathol Exp Neurol. 2020;79:407-418 pubmed 出版商
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Huhta H, Helminen O, Kauppila J, Salo T, Porvari K, Saarnio J, et al. The Expression of Toll-like Receptors in Normal Human and Murine Gastrointestinal Organs and the Effect of Microbiome and Cancer. J Histochem Cytochem. 2016;64:470-82 pubmed 出版商
Jeon Y, Kim C, Koh J, Chung D, Ha G. Pellino-1 confers chemoresistance in lung cancer cells by upregulating cIAP2 through Lys63-mediated polyubiquitination. Oncotarget. 2016;7:41811-41824 pubmed 出版商
Jamin A, Dehoux L, Dossier C, Fila M, Heming N, Monteiro R, et al. Toll-like receptor 3 expression and function in childhood idiopathic nephrotic syndrome. Clin Exp Immunol. 2015;182:332-45 pubmed 出版商
Chatillon J, Hamieh M, Bayeux F, Abasq C, Fauquembergue E, Drouet A, et al. Direct Toll-Like Receptor 8 signaling increases the functional avidity of human CD8+ T lymphocytes generated for adoptive T cell therapy strategies. Immun Inflamm Dis. 2015;3:1-13 pubmed 出版商
Zimmermann M, Aguilera F, Castellucci M, Rossato M, Costa S, Lunardi C, et al. Chromatin remodelling and autocrine TNFα are required for optimal interleukin-6 expression in activated human neutrophils. Nat Commun. 2015;6:6061 pubmed 出版商
Tengroth L, Arebro J, Kumlien Geor n S, Winqvist O, Cardell L. Deprived TLR9 expression in apparently healthy nasal mucosa might trigger polyp-growth in chronic rhinosinusitis patients. PLoS ONE. 2014;9:e105618 pubmed 出版商
Camacho Sandoval R, Del Río Estrada P, Rivero Arrieta A, Reyes Teran G, Bonifaz L. Differential partial activation phenotype and production of tumour necrosis factor-? by conventional dendritic cells in response to lipopolysaccharide in HIV+ viraemic subjects and HIV+ controllers. Clin Exp Immunol. 2014;178:489-503 pubmed 出版商
Bernard M, Han X, Inderbitzin S, Agbim I, Zhao H, Koziel H, et al. HIV-derived ssRNA binds to TLR8 to induce inflammation-driven macrophage foam cell formation. PLoS ONE. 2014;9:e104039 pubmed 出版商
Green T, Santos M, Ejaeidi A, Craft B, Lewis R, Cruse J. Toll-like receptor (TLR) expression of immune system cells from metastatic breast cancer patients with circulating tumor cells. Exp Mol Pathol. 2014;97:44-8 pubmed 出版商
Youn J, Shim H, Lee J, Ji A, Oh J, Hong N, et al. Detailed pathologic evaluation on endomyocardial biopsy provides long-term prognostic information in patients with acute myocarditis. Cardiovasc Pathol. 2014;23:139-44 pubmed 出版商
Wang C, Eng H, Lin K, Liu H, Chang C, Lin T. Functional polymorphisms of TLR8 are associated with hepatitis C virus infection. Immunology. 2014;141:540-8 pubmed 出版商
Abdi J, Mutis T, Garssen J, Redegeld F. Characterization of the Toll-like receptor expression profile in human multiple myeloma cells. PLoS ONE. 2013;8:e60671 pubmed 出版商
Harman A, Bye C, Nasr N, Sandgren K, Kim M, Mercier S, et al. Identification of lineage relationships and novel markers of blood and skin human dendritic cells. J Immunol. 2013;190:66-79 pubmed 出版商
Chamberlain N, Kim S, Vila O, Volin M, Volkov S, Pope R, et al. Ligation of TLR7 by rheumatoid arthritis synovial fluid single strand RNA induces transcription of TNF? in monocytes. Ann Rheum Dis. 2013;72:418-26 pubmed 出版商
Berger M, Hsieh C, Bakele M, Marcos V, Rieber N, Kormann M, et al. Neutrophils express distinct RNA receptors in a non-canonical way. J Biol Chem. 2012;287:19409-17 pubmed 出版商
Pang M, Bala S, Kodys K, Catalano D, Szabo G. Inhibition of TLR8- and TLR4-induced Type I IFN induction by alcohol is different from its effects on inflammatory cytokine production in monocytes. BMC Immunol. 2011;12:55 pubmed 出版商
Dasgupta G, Chentoufi A, You S, Falatoonzadeh P, Urbano L, Akhtarmalik A, et al. Engagement of TLR2 reverses the suppressor function of conjunctiva CD4+CD25+ regulatory T cells and promotes herpes simplex virus epitope-specific CD4+CD25- effector T cell responses. Invest Ophthalmol Vis Sci. 2011;52:3321-33 pubmed 出版商
Dasari P, Zola H, Nicholson I. Expression of Toll-like receptors by neonatal leukocytes. Pediatr Allergy Immunol. 2011;22:221-8 pubmed 出版商
Schwab N, Zozulya A, Kieseier B, Toyka K, Wiendl H. An imbalance of two functionally and phenotypically different subsets of plasmacytoid dendritic cells characterizes the dysfunctional immune regulation in multiple sclerosis. J Immunol. 2010;184:5368-74 pubmed 出版商
van den Berk L, Jansen B, Siebers Vermeulen K, Netea M, Latuhihin T, Bergevoet S, et al. Toll-like receptor triggering in cord blood mesenchymal stem cells. J Cell Mol Med. 2009;13:3415-26 pubmed 出版商
Biasin M, Piacentini L, Lo Caputo S, Naddeo V, Pierotti P, Borelli M, et al. TLR activation pathways in HIV-1-exposed seronegative individuals. J Immunol. 2010;184:2710-7 pubmed 出版商
Panda A, Qian F, Mohanty S, van Duin D, Newman F, Zhang L, et al. Age-associated decrease in TLR function in primary human dendritic cells predicts influenza vaccine response. J Immunol. 2010;184:2518-27 pubmed 出版商
Clancy R, Alvarez D, Komissarova E, Barrat F, Swartz J, Buyon J. Ro60-associated single-stranded RNA links inflammation with fetal cardiac fibrosis via ligation of TLRs: a novel pathway to autoimmune-associated heart block. J Immunol. 2010;184:2148-55 pubmed 出版商
Wu J, Meng Z, Jiang M, Zhang E, Trippler M, Broering R, et al. Toll-like receptor-induced innate immune responses in non-parenchymal liver cells are cell type-specific. Immunology. 2010;129:363-74 pubmed 出版商
Pietschmann K, Beetz S, Welte S, Martens I, Gruen J, Oberg H, et al. Toll-like receptor expression and function in subsets of human gammadelta T lymphocytes. Scand J Immunol. 2009;70:245-55 pubmed 出版商
Vatakis D, Nixon C, Bristol G, Zack J. Differentially stimulated CD4+ T cells display altered human immunodeficiency virus infection kinetics: implications for the efficacy of antiviral agents. J Virol. 2009;83:3374-8 pubmed 出版商
Sacre S, Lo A, Gregory B, Simmonds R, Williams L, Feldmann M, et al. Inhibitors of TLR8 reduce TNF production from human rheumatoid synovial membrane cultures. J Immunol. 2008;181:8002-9 pubmed
Clark R, Huang S, Murphy G, Mollet I, Hijnen D, Muthukuru M, et al. Human squamous cell carcinomas evade the immune response by down-regulation of vascular E-selectin and recruitment of regulatory T cells. J Exp Med. 2008;205:2221-34 pubmed 出版商
Cohen P, Koski G, Czerniecki B, Bunting K, Fu X, Wang Z, et al. STAT3- and STAT5-dependent pathways competitively regulate the pan-differentiation of CD34pos cells into tumor-competent dendritic cells. Blood. 2008;112:1832-43 pubmed 出版商
Zuiderwijk Sick E, van der Putten C, Bsibsi M, Deuzing I, de Boer W, Persoon Deen C, et al. Differentiation of primary adult microglia alters their response to TLR8-mediated activation but not their capacity as APC. Glia. 2007;55:1589-600 pubmed
Kaji M, Tanaka J, Sugita J, Kato N, Ibata M, Shono Y, et al. Ciprofloxacin inhibits lipopolysaccharide-induced toll-like receptor-4 and 8 expression on human monocytes derived from adult and cord blood. Ann Hematol. 2008;87:229-31 pubmed
Murciano C, Villamon E, Yáñez A, Murciano J, Mir A, O Connor J, et al. In vitro response to Candida albicans in cultures of whole human blood from young and aged donors. FEMS Immunol Med Microbiol. 2007;51:327-35 pubmed
Wong C, Cheung P, Ip W, Lam C. Intracellular signaling mechanisms regulating toll-like receptor-mediated activation of eosinophils. Am J Respir Cell Mol Biol. 2007;37:85-96 pubmed
Zola H, Swart B, Banham A, Barry S, Beare A, Bensussan A, et al. CD molecules 2006--human cell differentiation molecules. J Immunol Methods. 2007;319:1-5 pubmed
Xu S, Koldovsky U, Xu M, Wang D, Fitzpatrick E, Son G, et al. High-avidity antitumor T-cell generation by toll receptor 8-primed, myeloid- derived dendritic cells is mediated by IL-12 production. Surgery. 2006;140:170-8 pubmed
Levy O, Suter E, Miller R, Wessels M. Unique efficacy of Toll-like receptor 8 agonists in activating human neonatal antigen-presenting cells. Blood. 2006;108:1284-90 pubmed
Lee J, Wu C, Lee K, Chuang T, Katakura K, Liu Y, et al. Activation of anti-hepatitis C virus responses via Toll-like receptor 7. Proc Natl Acad Sci U S A. 2006;103:1828-33 pubmed
Hart O, Athié Morales V, O Connor G, Gardiner C. TLR7/8-mediated activation of human NK cells results in accessory cell-dependent IFN-gamma production. J Immunol. 2005;175:1636-42 pubmed
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产品信息
品牌 :
Novus
master code :
NBP2-23490
SKU号 :
NBP2-23490
产品名称 :
p62/泛肽结合蛋白p62抗体(5H7E2)
描述 :
The p62/SQSTM1 Antibody (5H7E2) from Novus Biologicals is a mouse monoclonal antibody to p62/SQSTM1. This antibody reacts with human, primate. The p62/SQSTM1 Antibody (5H7E2) has been validated for the following applications: Western Blot, Flow Cytometry, ELISA, Immunohistochemistry, Immunocytochemistry/Immunofluorescence, Immunohistochemistry-Paraffin.
靶标 :
p62/泛肽结合蛋白p62
类别 :
一抗
单位尺寸 :
0.1 ml (also 0.025 ml)
缓冲液 :
PBS, 0.5% 蛋白稳定剂
克隆性 :
单克隆
克隆 :
5H7E2
浓度 :
1.0毫克/毫升
共轭标签 :
未共轭
宿主 :
小鼠
免疫原 :
Partial recombinant human p62/SQSTM1 (between residues 100-400) expressed in E. coli [UniProt Q13501]
抗体亚型 :
IgG1
纯度 :
硫酸铵沉淀
物种 :
人类, 灵长类动物
基因符号 :
泛肽结合蛋白p62
catalog number base :
NBP2-23490
accessionNumbers :
Q13501
应用 :
免疫印迹, 流式细胞仪, 酶联免疫吸附测定, 免疫组化, 免疫细胞化学/免疫荧光, 免疫组化石蜡
2020美元 :
299
2021美元 :
283美元
别名 :
A170, Autophagy Receptor P62, DMRV, EBI3-associated protein of 60 kDa, EBI3-associated protein p60, EBIAP, FTDALS3, NADGP, ORCA, OSIL, oxidative stress induced like, p60PDB3, p62, p62B, Paget disease of bone 3, PDB3, phosphotyrosine independent ligand for the Lck SH2 domain p62, Phosphotyrosine-independent ligand for the Lck SH2 domain of 62 kDa, sequestosome 1, sequestosome-1, Ubiquitin-binding protein p62, ZIP3
储存 :
Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.
公司信息
Novus Biologicals
8100 Southpark Way, A-8
Littleton, CO 80120
technical@novusbio.com
https://www.novusbio.com
1-888-506-6887 303-730-1950
公司总部: 美国
Novus Biologicals的任务是开发最先进的新产品及市场行销来加速生物科研的新发现。藉由高效率的组织分工,Novus Biologicals建立了一个将生物学术团体的成果快速商品化的平台。我们的产品除了附有详细的产品资讯外,Novus Biologicals更提供完整的技术支援及服务。利用快速有效的市场通路以便迅速提供所有的科研学者最先进的研究试剂,Novus Biologicals扮演市场上重要的角色。