产品简要
公司名称 :
Novus Biologicals
其他品牌 :
IMGENEX
产品类型 :
抗体
产品名称 :
Toll样受体4抗体(76B357.1)-无叠氮物
目录 :
NBP2-27149
规格 :
0.1 mg (also 0.025 mg, 1 mg)
价格 :
449美元
克隆性 :
单克隆
宿主 :
小鼠
共轭标签 :
未共轭
克隆名称 :
76B357.1
反应物种 :
人类, 小鼠, 大鼠, 牛
应用 :
免疫印迹, 免疫组化, 免疫细胞化学, 中和反应, 流式细胞仪, 染色质免疫沉淀 , 免疫组化-石蜡切片, 免疫组化-冰冻切片
更多信息或购买 :
Novus Biologicals 产品网页
文章摘录数: 29
参考文献
Di Cerbo A, Giusti S, Mariotti F, Spaterna A, Rossi G, Magi G. Increased Expression of Toll-Like Receptor 4 in Skin of Dogs with Discoid Lupus Erythematous (DLE). Animals (Basel). 2021;11: pubmed 出版商
Khan H, Aamir K, Jusuf P, Sethi G, Sisinthy S, Ghildyal R, et al. Lauric acid ameliorates lipopolysaccharide (LPS)-induced liver inflammation by mediating TLR4/MyD88 pathway in Sprague Dawley (SD) rats. Life Sci. 2021;265:118750 pubmed 出版商
Bi Y, Ding Y, Wu J, Miao Z, Wang J, Wang F. Staphylococcus aureus induces mammary gland fibrosis through activating the TLR/NF-κB and TLR/AP-1 signaling pathways in mice. Microb Pathog. 2020;148:104427 pubmed 出版商
Mukherjee P, Hough G, Chattopadhyay A, Grijalva V, O Connor E, Meriwether D, et al. Role of enterocyte stearoyl-Co-A desaturase-1 in LDLR-null mice. J Lipid Res. 2018;59:1818-1840 pubmed 出版商
Haricharan S, Brown P. TLR4 has a TP53-dependent dual role in regulating breast cancer cell growth. Proc Natl Acad Sci U S A. 2015;112:E3216-25 pubmed 出版商
Degraaf A, Zasłona Z, Bourdonnay E, Peters Golden M. Prostaglandin E2 reduces Toll-like receptor 4 expression in alveolar macrophages by inhibition of translation. Am J Respir Cell Mol Biol. 2014;51:242-50 pubmed 出版商
Abdi J, Mutis T, Garssen J, Redegeld F. Characterization of the Toll-like receptor expression profile in human multiple myeloma cells. PLoS ONE. 2013;8:e60671 pubmed 出版商
Semar S, Klotz M, Letiembre M, Van Ginneken C, Braun A, Jost V, et al. Changes of the enteric nervous system in amyloid-? protein precursor transgenic mice correlate with disease progression. J Alzheimers Dis. 2013;36:7-20 pubmed 出版商
Jazaeri F, Tavangar S, Ghazi Khansari M, Khorramizadeh M, Mani A, Dehpour A. Cirrhosis is associated with development of tolerance to cardiac chronotropic effect of endotoxin in rats. Liver Int. 2013;33:368-74 pubmed 出版商
McCulloch L, Brown K, Mabbott N. Ablation of the cellular prion protein, PrPC, specifically on follicular dendritic cells has no effect on their maturation or function. Immunology. 2013;138:246-57 pubmed 出版商
Hsiao C, Kao Y, Huang S, Chuang J. Toll-like receptor-4 agonist inhibits motility and invasion of hepatoblastoma HepG2 cells in vitro. Pediatr Blood Cancer. 2013;60:248-53 pubmed 出版商
Zheng Y, Yang M, Rong T, Yuan X, Ma Y, Wang Z, et al. CD74 and macrophage migration inhibitory factor as therapeutic targets in gastric cancer. World J Gastroenterol. 2012;18:2253-61 pubmed 出版商
Liu Y, Fatheree N, Mangalat N, Rhoads J. Lactobacillus reuteri strains reduce incidence and severity of experimental necrotizing enterocolitis via modulation of TLR4 and NF-?B signaling in the intestine. Am J Physiol Gastrointest Liver Physiol. 2012;302:G608-17 pubmed 出版商
Janardhanam S, Prakasam S, Swaminathan V, Kodumudi K, Zunt S, Srinivasan M. Differential expression of TLR-2 and TLR-4 in the epithelial cells in oral lichen planus. Arch Oral Biol. 2012;57:495-502 pubmed 出版商
Weile C, Josefsen K, Buschard K. Glucose activation of islets of Langerhans up-regulates Toll-like receptor 5: possible mechanism of protection. Clin Exp Immunol. 2011;166:251-7 pubmed 出版商
Voss E, Skuljec J, Gudi V, Skripuletz T, Pul R, Trebst C, et al. Characterisation of microglia during de- and remyelination: can they create a repair promoting environment?. Neurobiol Dis. 2012;45:519-28 pubmed 出版商
Nowicki M, Kosacka J, Serke H, Bluher M, Spanel Borowski K. Altered sciatic nerve fiber morphology and endoneural microvessels in mouse models relevant for obesity, peripheral diabetic polyneuropathy, and the metabolic syndrome. J Neurosci Res. 2012;90:122-31 pubmed 出版商
Brandau S, Jakob M, Hemeda H, Bruderek K, Janeschik S, Bootz F, et al. Tissue-resident mesenchymal stem cells attract peripheral blood neutrophils and enhance their inflammatory activity in response to microbial challenge. J Leukoc Biol. 2010;88:1005-15 pubmed 出版商
Hafez M, Hayes K, Goldrick M, Grencis R, Roberts I. The K5 capsule of Escherichia coli strain Nissle 1917 is important in stimulating expression of Toll-like receptor 5, CD14, MyD88, and TRIF together with the induction of interleukin-8 expression via the mitogen-activated protein kinase pathway in ep. Infect Immun. 2010;78:2153-62 pubmed 出版商
Johnston M, Wang A, Catarino M, Ball L, Phan V, MacDonald J, et al. Extracts of the rat tapeworm, Hymenolepis diminuta, suppress macrophage activation in vitro and alleviate chemically induced colitis in mice. Infect Immun. 2010;78:1364-75 pubmed 出版商
Wu J, Meng Z, Jiang M, Zhang E, Trippler M, Broering R, et al. Toll-like receptor-induced innate immune responses in non-parenchymal liver cells are cell type-specific. Immunology. 2010;129:363-74 pubmed 出版商
Nowicki M, Muller K, Serke H, Kosacka J, Vilser C, Ricken A, et al. Oxidized low-density lipoprotein (oxLDL)-induced cell death in dorsal root ganglion cell cultures depends not on the lectin-like oxLDL receptor-1 but on the toll-like receptor-4. J Neurosci Res. 2010;88:403-12 pubmed 出版商
Worku M, Morris A. Binding of different forms of lipopolysaccharide and gene expression in bovine blood neutrophils. J Dairy Sci. 2009;92:3185-93 pubmed 出版商
Link A, Selejan S, Maack C, Lenz M, Bohm M. Phosphodiesterase 4 inhibition but not beta-adrenergic stimulation suppresses tumor necrosis factor-alpha release in peripheral blood mononuclear cells in septic shock. Crit Care. 2008;12:R159 pubmed 出版商
Lunardi C, Bason C, Dolcino M, Navone R, Simone R, Saverino D, et al. Antiflagellin antibodies recognize the autoantigens Toll-Like Receptor 5 and Pals 1-associated tight junction protein and induce monocytes activation and increased intestinal permeability in Crohn's disease. J Intern Med. 2009;265:250-65 pubmed 出版商
Cohen P, Koski G, Czerniecki B, Bunting K, Fu X, Wang Z, et al. STAT3- and STAT5-dependent pathways competitively regulate the pan-differentiation of CD34pos cells into tumor-competent dendritic cells. Blood. 2008;112:1832-43 pubmed 出版商
Yoshizaki A, Iwata Y, Komura K, Ogawa F, Hara T, Muroi E, et al. CD19 regulates skin and lung fibrosis via Toll-like receptor signaling in a model of bleomycin-induced scleroderma. Am J Pathol. 2008;172:1650-63 pubmed 出版商
Allam J, Peng W, Appel T, Wenghoefer M, Niederhagen B, Bieber T, et al. Toll-like receptor 4 ligation enforces tolerogenic properties of oral mucosal Langerhans cells. J Allergy Clin Immunol. 2008;121:368-374.e1 pubmed
Zanoni G, Navone R, Lunardi C, Tridente G, Bason C, Sivori S, et al. In celiac disease, a subset of autoantibodies against transglutaminase binds toll-like receptor 4 and induces activation of monocytes. PLoS Med. 2006;3:e358 pubmed
图像
图像 1 :
Novus Biologicals NBP2-27149 图像 1
Western Blot: TLR4 Antibody (76B357.1) - Azide Free [NBP2-27149] - Analysis of TLR4 using TLR4 antibody at 2 ug/mL on (A) human intestine and 6 ug/mL on (B) mouse intestine and C) rat intestine lysate.
产品信息
品牌 :
Novus Biologicals, a Bio-Techne Brand
catalog number base :
NBP2-27149
SKU号 :
NBP2-27149
产品名称 :
Toll样受体4抗体(76B357.1)-无叠氮物
描述 :
The TLR4 Antibody (76B357.1) - Azide Free from Novus is a mouse monoclonal antibody to TLR4. This antibody reacts with human, mouse, rat, porcine, bovine, mammal. The TLR4 Antibody (76B357.1) - Azide Free has been validated for the following applications: Western Blot, Flow Cytometry, Immunohistochemistry, Immunocytochemistry/ Immunofluorescence, Immunohistochemistry-Paraffin, Immunohistochemistry-Frozen, Flow (Cell Surface), Flow (Intracellular), Chromatin Immunoprecipitation (ChIP), CyTOF-ready, Knockout Validated, Knockdown Validated, Block/Neutralize.
靶标 :
Toll样受体4
类别 :
一抗
单位尺寸 :
0.1 mg (also 0.025 mg, 1 mg)
缓冲液 :
PBS
克隆性 :
单克隆
克隆 :
76B357.1
浓度 :
1.0毫克/毫升
共轭标签 :
未共轭
宿主 :
小鼠
免疫原 :
This TLR4 Antibody (76B357.1) was developed against a portion of amino acids 100-200 of human TLR4 (NP_612564).
抗体亚型 :
IgG2b Kappa
纯度 :
蛋白质G纯化
物种 :
人类, 小鼠, 大鼠, 猪, 牛, 哺乳动物
理论上的分子量 :
95.7 kDa
基因符号 :
Toll样受体4
应用 :
Western Blot, Flow Cytometry, Immunohistochemistry, Immunocytochemistry/ Immunofluorescence, Immunohistochemistry-Paraffin, Immunohistochemistry-Frozen, Flow (Cell Surface), Flow (Intracellular), Chromatin Immunoprecipitation (ChIP), CyTOF-ready, Knockout Validated, Knockdown Validated, Block/Neutralize
美元 :
449美元
别名 :
ARMD10, CD_antigen: CD284, CD284, CD284 antigen, EC 3.2.2.6, EC:3.2.2.6, homolog of Drosophila toll, hToll, TLR4, TLR-4, TOLL, toll like receptor 4 protein, toll-like receptor 4
储存 :
Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.
更多信息或购买 :
Novus Biologicals 产品网页
公司信息
Novus Biologicals
10771 E Easter Ave
Centennial, CO 80112
technical@novusbio.com
https://www.novusbio.com
1-888-506-6887 303-730-1950
公司总部: 美国
Novus Biologicals的任务是开发最先进的新产品及市场行销来加速生物科研的新发现。藉由高效率的组织分工，Novus Biologicals建立了一个将生物学术团体的成果快速商品化的平台。我们的产品除了附有详细的产品资讯外，Novus Biologicals更提供完整的技术支援及服务。利用快速有效的市场通路以便迅速提供所有的科研学者最先进的研究试剂，Novus Biologicals扮演市场上重要的角色。