产品简要
公司名称 :
Novus Biologicals
其他品牌 :
IMGENEX
产品类型 :
抗体
产品名称 :
p21/CIP1/CDKN1A抗体(WA-1)
目录 :
NBP2-29463
规格 :
0.1 mg (also 20 ug)
价格 :
379美元
克隆性 :
单克隆
宿主 :
小鼠
共轭标签 :
未共轭
克隆名称 :
WA-1
反应物种 :
人类, 小鼠, 大鼠, 黑猩猩
应用 :
免疫印迹, 免疫组化, 免疫细胞化学, 流式细胞仪, 免疫组化-石蜡切片
更多信息或购买 :
文章摘录数: 24
出版应用/物种/样本/稀释参考文献
  • 免疫印迹; 小鼠; 1:50; 图 7a
Xiang J, Yang S, Xin N, Gaertig M, Reeves R, Li S, et al. DYRK1A regulates Hap1-Dcaf7/WDR68 binding with implication for delayed growth in Down syndrome. Proc Natl Acad Sci U S A. 2017;114:E1224-E1233 pubmed 出版商
Saleh T, Alhesa A, Al Balas M, Abuelaish O, Mansour A, Awad H, et al. Expression of therapy-induced senescence markers in breast cancer samples upon incomplete response to neoadjuvant chemotherapy. Biosci Rep. 2021;41: pubmed 出版商
Kaczorowski A, Tolstov Y, Falkenstein M, Vasioukhin V, Prigge E, Geisler C, et al. Rearranged ERG confers robustness to prostate cancer cells by subverting the function of p53. Urol Oncol. 2020;38:736.e1-736.e10 pubmed 出版商
Couture R, Mora N, Al Bittar S, Najih M, Touaibia M, Martin L. Luteolin modulates gene expression related to steroidogenesis, apoptosis, and stress response in rat LC540 tumor Leydig cells. Cell Biol Toxicol. 2019;: pubmed 出版商
Mishra P, Paital B, Jena S, Swain S, Kumar S, Yadav M, et al. Possible activation of NRF2 by Vitamin E/Curcumin against altered thyroid hormone induced oxidative stress via NFĸB/AKT/mTOR/KEAP1 signalling in rat heart. Sci Rep. 2019;9:7408 pubmed 出版商
Zhou X, Liu S, Lin X, Xu L, Mao X, Liu J, et al. Metformin Inhibit Lung Cancer Cell Growth and Invasion in Vitro as Well as Tumor Formation in Vivo Partially by Activating PP2A. Med Sci Monit. 2019;25:836-846 pubmed 出版商
Aratani S, Tagawa M, Nagasaka S, Sakai Y, Shimizu A, Tsuruoka S. Radiation-induced premature cellular senescence involved in glomerular diseases in rats. Sci Rep. 2018;8:16812 pubmed 出版商
Huang X, Huang R, Gou S, Wang Z, Liao Z, Wang H. Platinum(IV) complexes conjugated with phenstatin analogue as inhibitors of microtubule polymerization and reverser of multidrug resistance. Bioorg Med Chem. 2017;25:4686-4700 pubmed 出版商
Ge X, Pettan Brewer C, Morton J, Carter K, Fatemi S, Rabinovitch P, et al. Mitochondrial catalase suppresses naturally occurring lung cancer in old mice. Pathobiol Aging Age Relat Dis. 2015;5:28776 pubmed 出版商
Meads M, Fang B, Mathews L, Gemmer J, Nong L, Rosado Lopez I, et al. Targeting PYK2 mediates microenvironment-specific cell death in multiple myeloma. Oncogene. 2016;35:2723-34 pubmed 出版商
Romanov V, Pospelov V, Pospelova T. Cyclin-dependent kinase inhibitor p21(Waf1): contemporary view on its role in senescence and oncogenesis. Biochemistry (Mosc). 2012;77:575-84 pubmed 出版商
Tagoug I, Sauty De Chalon A, Dumontet C. Inhibition of IGF-1 signalling enhances the apoptotic effect of AS602868, an IKK2 inhibitor, in multiple myeloma cell lines. PLoS ONE. 2011;6:e22641 pubmed 出版商
Koike M, Yutoku Y, Koike A. Accumulation of p21 proteins at DNA damage sites independent of p53 and core NHEJ factors following irradiation. Biochem Biophys Res Commun. 2011;412:39-43 pubmed 出版商
Wedel S, Hudak L, Seibel J, Juengel E, Tsaur I, Wiesner C, et al. Inhibitory effects of the HDAC inhibitor valproic acid on prostate cancer growth are enhanced by simultaneous application of the mTOR inhibitor RAD001. Life Sci. 2011;88:418-24 pubmed 出版商
Wedel S, Hudak L, Seibel J, Juengel E, Oppermann E, Haferkamp A, et al. Critical analysis of simultaneous blockage of histone deacetylase and multiple receptor tyrosine kinase in the treatment of prostate cancer. Prostate. 2011;71:722-35 pubmed 出版商
Elamin M, Shinwari Z, Hendrayani S, Al Hindi H, Al Shail E, Khafaga Y, et al. Curcumin inhibits the Sonic Hedgehog signaling pathway and triggers apoptosis in medulloblastoma cells. Mol Carcinog. 2010;49:302-14 pubmed 出版商
Juengel E, Engler J, Natsheh I, Jones J, Mickuckyte A, Hudak L, et al. Combining the receptor tyrosine kinase inhibitor AEE788 and the mammalian target of rapamycin (mTOR) inhibitor RAD001 strongly inhibits adhesion and growth of renal cell carcinoma cells. BMC Cancer. 2009;9:161 pubmed 出版商
Nobre R, Herráez Hernández E, Fei J, Langbein L, Kaden S, Grone H, et al. E7 oncoprotein of novel human papillomavirus type 108 lacking the E6 gene induces dysplasia in organotypic keratinocyte cultures. J Virol. 2009;83:2907-16 pubmed 出版商
Luty W, Rodeberg D, Parness J, Vyas Y. Antiparallel segregation of notch components in the immunological synapse directs reciprocal signaling in allogeneic Th:DC conjugates. J Immunol. 2007;179:819-29 pubmed
Rossner P, Binkova B, Milcova A, Solansky I, Zidzik J, Lyubomirova K, et al. Air pollution by carcinogenic PAHs and plasma levels of p53 and p21(WAF1) proteins. Mutat Res. 2007;620:34-40 pubmed
Nair A, Shishodia S, Ahn K, Kunnumakkara A, Sethi G, Aggarwal B. Deguelin, an Akt inhibitor, suppresses IkappaBalpha kinase activation leading to suppression of NF-kappaB-regulated gene expression, potentiation of apoptosis, and inhibition of cellular invasion. J Immunol. 2006;177:5612-22 pubmed
Scott M, Ingram A, Ball K. PDK1-dependent activation of atypical PKC leads to degradation of the p21 tumour modifier protein. EMBO J. 2002;21:6771-80 pubmed
Rossner P, Binkova B, Chvatalova I, Sram R. Acrylonitrile exposure: the effect on p53 and p21(WAF1) protein levels in the blood plasma of occupationally exposed workers and in vitro in human diploid lung fibroblasts. Mutat Res. 2002;517:239-50 pubmed
Blaydes J, Luciani M, Pospisilova S, Ball H, Vojtesek B, Hupp T. Stoichiometric phosphorylation of human p53 at Ser315 stimulates p53-dependent transcription. J Biol Chem. 2001;276:4699-708 pubmed
产品信息
品牌 :
Novus
master code :
NBP2-29463
SKU号 :
NBP2-29463
产品名称 :
p21/CIP1/CDKN1A抗体(WA-1)
描述 :
The p21/CIP1/CDKN1A Antibody (WA-1) from NBP2-29463 is a nbp2-29463 antibody to . This antibody reacts with apoptosis, breast cancer, cancer, cell cycle and replication, dna repair, phospho specific. The p21/CIP1/CDKN1A Antibody (WA-1) has been validated for the following applications: P38936.
靶标 :
p21/CIP1/CDKN1A
类别 :
一抗
单位尺寸 :
0.1 mg (also 20 ug)
缓冲液 :
10 mM PBS with 0.05% BSA
克隆性 :
单克隆
克隆 :
WA-1
浓度 :
0.2毫克/毫升
共轭标签 :
未共轭
宿主 :
小鼠
免疫原 :
人类重组p21/CIP1/CDKN1A蛋白
抗体亚型 :
IgG1 Kappa
纯度 :
蛋白质A或G纯化
物种 :
Human, Mouse, Rat, Chimpanzee, Monkey
特异性 :
This MAb recognizes a 21kDa protein, identified as the p21WAF1 tumor suppressor protein
理论上的分子量 :
21 kDa
基因符号 :
CDKN1A
accessionNumbers :
P38936
应用 :
免疫印迹, 流式细胞仪, 免疫组化, 免疫细胞化学/免疫荧光, 免疫组化石蜡
美元 :
379美元
别名 :
CAP20cyclin-dependent kinase inhibitor 1, CDK-interacting protein 1, CDKN1melanoma differentiation associated protein 6, CIP1WAF1CDK-interaction protein 1, cyclin-dependent kinase inhibitor 1A (p21, Cip1), MDA6, MDA-6, Melanoma differentiation-associated protein 6, p21, p21CIP1, p21Cip1/Waf1, PIC1, SDI1DNA synthesis inhibitor, wild-type p53-activated fragment 1
储存 :
存放在4C
更多信息或购买 :
公司信息
Novus Biologicals
10771 E Easter Ave
Centennial, CO 80112
technical@novusbio.com
https://www.novusbio.com
1-888-506-6887 303-730-1950
公司总部: 美国
Novus Biologicals的任务是开发最先进的新产品及市场行销来加速生物科研的新发现。藉由高效率的组织分工,Novus Biologicals建立了一个将生物学术团体的成果快速商品化的平台。我们的产品除了附有详细的产品资讯外,Novus Biologicals更提供完整的技术支援及服务。利用快速有效的市场通路以便迅速提供所有的科研学者最先进的研究试剂,Novus Biologicals扮演市场上重要的角色。