产品简要
公司名称 :
Novus Biologicals
其他品牌 :
IMGENEX
产品类型 :
抗体
产品名称 :
肿瘤坏死因子甲抗体(SPM543)
目录 :
NBP2-34372
规格 :
0.02毫克
价格 :
149美元
克隆性 :
单克隆
宿主 :
小鼠
共轭标签 :
未共轭
克隆名称 :
SPM543
反应物种 :
人类, 小鼠, 大鼠,
应用 :
免疫组化, 免疫细胞化学, 流式细胞仪, 免疫组化-石蜡切片, 免疫组化-冰冻切片
更多信息或购买 :
文章摘录数: 4
参考文献
Zilberman Itskovich S, Abu Hamad R, Zarura R, Sova M, Hachmo Y, Stark M, et al. Human mesenchymal stromal cells ameliorate complement induced inflammatory cascade and improve renal functions in a rat model of ischemia-reperfusion induced acute kidney injury. PLoS ONE. 2019;14:e0222354 pubmed 出版商
Valkonen S, Holopainen M, Colas R, Impola U, Dalli J, Käkelä R, et al. Lipid mediators in platelet concentrate and extracellular vesicles: Molecular mechanisms from membrane glycerophospholipids to bioactive molecules. Biochim Biophys Acta Mol Cell Biol Lipids. 2019;: pubmed 出版商
Xu M, Chang H, Jung X, Moro A, Chou C, King J, et al. Deficiency in hormone-sensitive lipase accelerates the development of pancreatic cancer in conditional KrasG12D mice. BMC Cancer. 2018;18:797 pubmed 出版商
Kurupati R, Zhou X, Xiang Z, Keller L, Ertl H. Safety and immunogenicity of a potential checkpoint blockade vaccine for canine melanoma. Cancer Immunol Immunother. 2018;: pubmed 出版商
图像
图像 1 :
Novus Biologicals NBP2-34372 图像 1
Immunohistochemistry-Paraffin: TNF-alpha Antibody (SPM543) [NBP2-34372] - Formalin-fixed, paraffin-embedded human Erdheim-Chester disease (also known as polyostotic sclerosing histiocytosis) stained with TNF-alpha Antibody (SPM543).
产品信息
品牌 :
Novus
master code :
NBP2-34372
SKU号 :
NBP2-34372.02毫克
产品名称 :
肿瘤坏死因子甲抗体(SPM543)
描述 :
The TNF-alpha Antibody (SPM543) from Novus Biologicals is a mouse monoclonal antibody to TNF-alpha. This antibody reacts with human, mouse, rat, canine, feline, rabbit, zebrafish. The TNF-alpha Antibody (SPM543) has been validated for the following applications: Flow Cytometry, Immunohistochemistry, Immunocytochemistry/Immunofluorescence, Immunohistochemistry-Paraffin, Immunohistochemistry-Frozen.
靶标 :
肿瘤坏死因子甲
类别 :
一抗
单位尺寸 :
0.02毫克
缓冲液 :
10 mM PBS with 0.05% BSA
克隆性 :
单克隆
克隆 :
SPM543
浓度 :
0.2毫克/毫升
共轭标签 :
未共轭
宿主 :
小鼠
免疫原 :
A hexadecapeptide corresponding to aa115-130 of human TNF-alpha, conjugated to thyroglobulin
抗体亚型 :
IgG1 Kappa
纯度 :
蛋白质A纯化
物种 :
人类, 小鼠, 大鼠, 狗, 猫, 兔, 斑马鱼
特异性 :
Tumor Necrosis Factor Alpha (TNF alpha) is a protein secreted by lipopolysaccharide-stimulated macrophages, and causes tumor necrosis when injected into tumor bearing mice. TNF alpha is believed to mediate pathogenic shock and tissue injury associated with endotoxemia. TNF alpha exists as a multimer of two, three, or five non-covalently linked units, but shows a single 17kDa band following SDS PAGE under non-reducing conditions. TNF alpha is closely related to the 25kDa protein Tumor Necrosis Factor beta (lymphotoxin), sharing the same receptors and cellular actions. TNF alpha causes cytolysis of certain transformed cells, being synergistic with interferon gamma in its cytotoxicity. Although it has little effect on many cultured normal human cells, TNF alpha appears to be directly toxic to vascular endothelial cells. Other actions of TNF alpha include stimulating growth of human fibroblasts and other cell lines, activating polymorphonuclear neutrophils and osteoclasts, and induction of interleukin 1, prostaglandin E2 and collagenase production. TNF alpha is currently being evaluated in treatment of certain cancers and AIDS Related Complex.
理论上的分子量 :
17 kDa
基因符号 :
肿瘤坏死因子
catalog number base :
NBP2-34372
accessionNumbers :
P01375
应用 :
流式细胞仪, 免疫组化, 免疫细胞化学/免疫荧光, 免疫组化石蜡, 免疫组化冷冻
2020美元 :
129
2021美元 :
149美元
别名 :
APC1 protein, Cachectin, DIF, TNF, monocyte-derived, TNF-a, TNF-alphacachectin, TNFATNF, macrophage-derived, TNFSF2TNF superfamily, member 2, tumor necrosis factor, tumor necrosis factor (TNF superfamily, member 2), tumor necrosis factor alpha, Tumor necrosis factor ligand superfamily member 2, tumor necrosis factor-alpha
储存 :
存放在4C
更多信息或购买 :
公司信息
Novus Biologicals
8100 Southpark Way, A-8
Littleton, CO 80120
technical@novusbio.com
https://www.novusbio.com
1-888-506-6887 303-730-1950
公司总部: 美国
Novus Biologicals的任务是开发最先进的新产品及市场行销来加速生物科研的新发现。藉由高效率的组织分工,Novus Biologicals建立了一个将生物学术团体的成果快速商品化的平台。我们的产品除了附有详细的产品资讯外,Novus Biologicals更提供完整的技术支援及服务。利用快速有效的市场通路以便迅速提供所有的科研学者最先进的研究试剂,Novus Biologicals扮演市场上重要的角色。