产品简要
公司名称 :
Novus Biologicals
其他品牌 :
IMGENEX
产品类型 :
抗体
产品名称 :
B7-2/CD86抗体(C86/1146)
目录 :
NBP2-44514
规格 :
0.02毫克
价格 :
149美元
克隆性 :
单克隆
宿主 :
小鼠
共轭标签 :
未共轭
克隆名称 :
C86/1146
反应物种 :
人类, 小鼠, 大鼠
应用 :
免疫印迹, 免疫组化, 免疫细胞化学, 流式细胞仪, 免疫组化-石蜡切片
更多信息或购买 :
Novus Biologicals 产品网页
文章摘录数: 3
参考文献
Khalmuratova R, Shin H, Kim D, Park J. Interleukin (IL)-13 and IL-17A contribute to neo-osteogenesis in chronic rhinosinusitis by inducing RUNX2. EBioMedicine. 2019;46:330-341 pubmed 出版商
Mizuhashi K, Nagata M, Matsushita Y, Ono W, Ono N. Growth Plate Borderline Chondrocytes Behave as Transient Mesenchymal Precursor Cells. J Bone Miner Res. 2019;34:1387-1392 pubmed 出版商
Ferrari N, Riggio A, Mason S, McDonald L, King A, Higgins T, et al. Runx2 contributes to the regenerative potential of the mammary epithelium. Sci Rep. 2015;5:15658 pubmed 出版商
图像
图像 1 :
Novus Biologicals NBP2-44514 图像 1
Knockout Validated: B7-2/CD86 Antibody (C86/1146) [NBP2-44514] - Western blot shows lysates of Ramos human Burkitt's lymphoma parental cell line and B7-2 knockout (KO) Ramos cell line. PVDF membrane was probed with 1.0 ug/mL of Mouse Anti-Human B7-2 Monoclonal Antibody (Catalog # NBP2-44514) followed by HRP-conjugated Anti-Mouse IgG Secondary Antibody (Catalog #HAF018). Specific band was detected for B7-2 at approximately 90 kDa (as indicated) in the parental Ramos cell line, but is not detectable in the knockout Ramos cell line. This experiment was conducted under reducing conditions.
产品信息
品牌 :
Novus
master code :
NBP2-44514
SKU号 :
NBP2-44514.02毫克
产品名称 :
B7-2/CD86抗体(C86/1146)
描述 :
The B7-2/CD86 Antibody (C86/1146) from Novus Biologicals is a mouse monoclonal antibody to B7-2/CD86. This antibody reacts with human, mouse, rat. The B7-2/CD86 Antibody (C86/1146) has been validated for the following applications: Western Blot, Flow Cytometry, Immunohistochemistry, Immunocytochemistry/Immunofluorescence, Immunohistochemistry-Paraffin, Knockout Validated.
靶标 :
B7-2/CD86
类别 :
一抗
单位尺寸 :
0.02毫克
缓冲液 :
10 mM PBS with 0.05% BSA
克隆性 :
单克隆
克隆 :
C86/1146
浓度 :
0.2毫克/毫升
共轭标签 :
未共轭
宿主 :
小鼠
免疫原 :
重组人类全长CD86蛋白
抗体亚型 :
IgG1 Kappa
纯度 :
蛋白质A或G纯化
物种 :
人类, 小鼠, 大鼠
特异性 :
Recognizes a protein of 70kDa, which is identified as CD86. CD86 is a type I transmembrane glycoprotein and a member of the immunoglobulin superfamily of cell surface receptors. It is expressed at high levels on resting peripheral monocytes and dendritic cells and at very low density on resting B and T lymphocytes. CD86 expression is rapidly upregulated by B cell specific stimuli with peak expression at 18 to 42 hours after stimulation. CD86, along with CD80/B71, is an important accessory molecule in T cell co-stimulation via its interaction with CD28 and CD152/CTLA4. Since CD86 has rapid kinetics of induction, it is believed to be the major CD28 ligand expressed early in the immune response. It is also found on malignant Hodgkin and Reed Sternberg (HRS) cells in Hodgkin's disease.
理论上的分子量 :
70 kDa
基因符号 :
CD86
catalog number base :
NBP2-44514
accessionNumbers :
P42081
应用 :
免疫印迹, 流式细胞仪, 免疫组化, 免疫细胞化学/免疫荧光, 免疫组化石蜡, 基因敲除验证
2020美元 :
149
2021美元 :
149美元
别名 :
Activation B7-2 antigen, B70, B7-2, B7-2 antigen, B-lymphocyte activation antigen B7-2, BU63, CD28 antigen ligand 2, CD28LG2B7-2 antigen), CD86 antigen, CD86 molecule, CTLA-4 counter-receptor B7.2, FUN-1, LAB72, MGC34413, T-lymphocyte activation antigen CD86
储存 :
存放在4C
更多信息或购买 :
Novus Biologicals 产品网页
公司信息
Novus Biologicals
8100 Southpark Way, A-8
Littleton, CO 80120
technical@novusbio.com
https://www.novusbio.com
1-888-506-6887 303-730-1950
公司总部: 美国
Novus Biologicals的任务是开发最先进的新产品及市场行销来加速生物科研的新发现。藉由高效率的组织分工，Novus Biologicals建立了一个将生物学术团体的成果快速商品化的平台。我们的产品除了附有详细的产品资讯外，Novus Biologicals更提供完整的技术支援及服务。利用快速有效的市场通路以便迅速提供所有的科研学者最先进的研究试剂，Novus Biologicals扮演市场上重要的角色。