产品简要
公司名称 :
Novus Biologicals
其他品牌 :
IMGENEX
产品类型 :
抗体
产品名称 :
Wilms瘤抑癌基因抗体(Wilms瘤抑癌基因/857+6F-H2)
目录 :
NBP2-44607
规格 :
0.02毫克
价格 :
149美元
克隆性 :
单克隆
宿主 :
小鼠
共轭标签 :
未共轭
克隆名称 :
Wilms瘤抑癌基因/857+6F-H2
反应物种 :
人类, 小鼠, 大鼠
应用 :
免疫组化, 免疫组化-石蜡切片, 免疫组化-冰冻切片
更多信息或购买 :
Novus Biologicals 产品网页
文章摘录数: 5
出版应用/物种/样本/稀释参考文献
  • 免疫组化-冰冻切片; 小鼠; 1:200; 图 1b
Chen X, Zhao Y, Xu J, Bao J, Zhao J, Chen J, et al. The Nephroprotective Effect of TNF Receptor-Associated Factor 6 (TRAF6) Blockade on LPS-Induced Acute Renal Injury Through the Inhibition if Inflammation and Oxidative Stress. Med Sci Monit. 2020;26:e919698 pubmed 出版商
Luo W, Chen X, Ye L, Chen X, Jia W, Zhao Y, et al. Kaempferol attenuates streptozotocin-induced diabetic nephropathy by downregulating TRAF6 expression: The role of TRAF6 in diabetic nephropathy. J Ethnopharmacol. 2020;:113553 pubmed 出版商
Chen X, Zhang X, Xu J, Zhao Y, Bao J, Zheng Z, et al. AZD4547 Attenuates Lipopolysaccharide-Induced Acute Kidney Injury by Inhibiting Inflammation: The Role of FGFR1 in Renal Tubular Epithelial Cells. Drug Des Devel Ther. 2020;14:833-844 pubmed 出版商
Zheng C, Huang L, Luo W, Yu W, Hu X, Guan X, et al. Inhibition of STAT3 in tubular epithelial cells prevents kidney fibrosis and nephropathy in STZ-induced diabetic mice. Cell Death Dis. 2019;10:848 pubmed 出版商
Liang G, Song L, Chen Z, Qian Y, Xie J, Zhao L, et al. Fibroblast growth factor 1 ameliorates diabetic nephropathy by an anti-inflammatory mechanism. Kidney Int. 2018;93:95-109 pubmed 出版商
图像
图像 1 :
Novus Biologicals NBP2-44607 图像 1
Immunohistochemistry-Paraffin: WT1 Antibody (WT1/857 + 6F-H2) [NBP2-44607] - Formalin-fixed, paraffin-embedded human Mesothelioma stained with WT1 Antibody (WT1/857 + 6F-H2).
产品信息
品牌 :
Novus
master code :
NBP2-44607
SKU号 :
NBP2-44607.02毫克
产品名称 :
Wilms瘤抑癌基因抗体(Wilms瘤抑癌基因/857+6F-H2)
描述 :
The WT1 Antibody (WT1/857 + 6F-H2) from Novus Biologicals is a mouse monoclonal antibody to WT1. This antibody reacts with human, rat. The WT1 Antibody (WT1/857 + 6F-H2) has been validated for the following applications: Immunohistochemistry, Immunohistochemistry-Paraffin.
靶标 :
Wilms瘤抑癌基因
类别 :
一抗
单位尺寸 :
0.02毫克
缓冲液 :
10 mM PBS with 0.05% BSA
克隆性 :
单克隆
克隆 :
Wilms瘤抑癌基因/857+6F-H2
浓度 :
0.2毫克/毫升
共轭标签 :
未共轭
宿主 :
小鼠
免疫原 :
Recombinant full length human WT1 protein (WT1/857); Recombinant fragment aa1-181 of human WT1 (6F-H2)
抗体亚型 :
IgG1 Kappa
纯度 :
蛋白质A或G纯化
物种 :
人类, 大鼠
特异性 :
Recognizes a 47-55kDa-tumor suppressor protein, identified as Wilm's Tumor (WT1) protein. The antibody reacts with all isoforms of the full-length WT1 and also identifies WT1 lacking exon 2-encoded amino acids, frequently found in subsets of sporadic Wilm s tumors.WT1, a sporadic and familial pediatric kidney tumor, is genetically heterogeneous. Wilm s tumor is associated with mutations of WT1, a zinc-finger transcription factor that is essential for the development of the metanephric kidney and the urogenital system. The WT1 gene is normally expressed in fetal kidney and mesothelium, and its expression has been suggested as a marker for Wilm s tumor and mesothelioma. WT1 protein has been identified in proliferative mesothelial cells, malignant mesothelioma, ovarian carcinoma, gonadoblastoma, nephroblastoma, and desmoplastic small round cell tumor. Lung adenocarcinomas rarely stain positive with this antibody. WT1 protein expression in mesothelial cells has become a reliable marker for the diagnosis of mesotheliomas.
基因符号 :
Wilms瘤抑癌基因
catalog number base :
NBP2-44607
accessionNumbers :
P19544
应用 :
免疫组化, 免疫组化石蜡
2020美元 :
129
2021美元 :
149美元
别名 :
AWT1, NPHS4GUD, WAGR, 肾母细胞瘤1, 肾母细胞瘤蛋白, 机智-2, WT33
储存 :
存放在4C
更多信息或购买 :
Novus Biologicals 产品网页
公司信息
Novus Biologicals
8100 Southpark Way, A-8
Littleton, CO 80120
technical@novusbio.com
https://www.novusbio.com
1-888-506-6887 303-730-1950
公司总部: 美国
Novus Biologicals的任务是开发最先进的新产品及市场行销来加速生物科研的新发现。藉由高效率的组织分工，Novus Biologicals建立了一个将生物学术团体的成果快速商品化的平台。我们的产品除了附有详细的产品资讯外，Novus Biologicals更提供完整的技术支援及服务。利用快速有效的市场通路以便迅速提供所有的科研学者最先进的研究试剂，Novus Biologicals扮演市场上重要的角色。