产品简要
公司名称 :
Novus Biologicals
其他品牌 :
IMGENEX
产品类型 :
抗体
产品名称 :
HLA DRB1抗体(SPM423)
目录 :
NBP2-45313
规格 :
0.1 mg (also 0.02 mg)
价格 :
329美元
克隆性 :
单克隆
宿主 :
小鼠
共轭标签 :
未共轭
克隆名称 :
SPM423
反应物种 :
人类
应用 :
免疫印迹, 免疫组化, 免疫细胞化学, 流式细胞仪, 免疫组化-石蜡切片
更多信息或购买 :
文章摘录数: 1
参考文献
Garrison C, Lastwika K, Zhang Y, Li C, Lampe P. Proteomic Analysis, Immune Dysregulation, and Pathway Interconnections with Obesity. J Proteome Res. 2017;16:274-287 pubmed 出版商
图像
图像 1 :
Novus Biologicals NBP2-45313 图像 1
Western Blot: HLA DRB1 Antibody (SPM423) [NBP2-45313] - Western Blot Analysis of human Spleen tissue lysate using HLA DRB1 Antibody (SPM423).
产品信息
品牌 :
Novus
master code :
NBP2-45313
SKU号 :
NBP2-45313.1毫克
产品名称 :
HLA DRB1抗体(SPM423)
描述 :
The HLA DRB1 Antibody (SPM423) from Novus is a mouse monoclonal antibody to HLA DRB1. This antibody reacts with human, monkey, mouse (negative). The HLA DRB1 Antibody (SPM423) has been validated for the following applications: Western Blot, Flow Cytometry, Immunohistochemistry, Immunohistochemistry-Paraffin, Immunofluorescence.
靶标 :
HLA DRB1
类别 :
一抗
单位尺寸 :
0.1 mg (also 0.02 mg)
缓冲液 :
10 mM PBS with 0.05% BSA
克隆性 :
单克隆
克隆 :
SPM423
浓度 :
0.2毫克/毫升
共轭标签 :
未共轭
宿主 :
小鼠
免疫原 :
Activated human peripheral blood mononuclear cells
抗体亚型 :
IgG2b Kappa
纯度 :
蛋白质A或G纯化
物种 :
Human, Monkey, Mouse (Negative)
特异性 :
This MAb reacts with a 28kDa chain of HLA-DRB1 antigen, a member of MHC class II molecules. It does not cross react with HLA-DP and HLA-DQ. The L243 antibody recognizes a different epitope than the LN3 monoclonal antibody, and these antibodies do not cross-block binding to each other's respective epitopes. HLA-DR is a heterodimeric cell surface glycoprotein comprised of a 36kDa alpha (heavy) chain and a 28kDa beta (light) chain. It is expressed on B-cells, activated T-cells, monocytes/macrophages, dendritic cells and other non-professional APCs. In conjunction with the CD3/TCR complex and CD4 molecules, HLA-DR is critical for efficient peptide presentation to CD4+ T cells. It is an excellent histiocytic marker in paraffin sections producing intense staining. True histiocytic neoplasms are similarly positive. HLA-DR antigens also occur on a variety of epithelial cells and their corresponding neoplastic counterparts. Loss of HLA-DR expression is related to tumor microenvironment and predicts adverse outcome in diffuse large B-cell lymphoma.
基因符号 :
HLA-DRB1
catalog number base :
NBP2-45313
应用 :
免疫印迹, 流式细胞仪, 免疫组化, 免疫组化石蜡, 免疫荧光
美元 :
329美元
别名 :
Clone P2-beta-3, DR1, DR-1, DR12, DR-12, DR13, DR-13, DR14, DR-14, DR16, DR-16, DR4, DR-4, DR5, DR-5, DR7, DR-7, DR8, DR-8, DR9, DR-9, DRB1, DRw10, DRw11, DRw8, DW2.2/DR2.2, FLJ75017, FLJ76359, HLA class II antigen beta chain, HLA class II histocompatibility antigen, DR-1 beta chain, HLA-DR1B, HLA-DRB, HLA-DRB1*, HLA-DRB2, HLA-DR-beta 1, human leucocyte antigen DRB1, leucocyte antigen DR beta 1 chain, leucocyte antigen DRB1, lymphocyte antigen DRB1, major histocompatibility complex, class II, DR beta 1, MHC class II antigen DRB1*1, MHC class II antigen DRB1*10, MHC class II antigen DRB1*11, MHC class II antigen DRB1*12, MHC class II antigen DRB1*13, MHC class II antigen DRB1*14, MHC class II antigen DRB1*15, MHC class II antigen DRB1*16, MHC class II antigen DRB1*3, MHC class II antigen DRB1*4, MHC class II antigen DRB1*7, MHC class II antigen DRB1*8, MHC class II antigen DRB1*9, MHC class II antigen HLA-DR13, MHC class II HLA-DR beta 1 chain, MHC class II HLA-DR-beta cell surface gly
储存 :
存放在4C
更多信息或购买 :
公司信息
Novus Biologicals
8100 Southpark Way, A-8
Littleton, CO 80120
technical@novusbio.com
https://www.novusbio.com
1-888-506-6887 303-730-1950
公司总部: 美国
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