产品简要
公司名称 :
Novus Biologicals
其他品牌 :
IMGENEX
产品类型 :
抗体
产品名称 :
Glypican 3 Antibody (GPC3/863) - Azide and BSA Free
目录 :
NBP2-47762.1毫克
规格 :
0.1毫克
价格 :
349美元
克隆性 :
单克隆
宿主 :
小鼠
共轭标签 :
未共轭
克隆名称 :
GPC3/863
反应物种 :
人类, 大鼠
应用 :
免疫组化, 免疫细胞化学, 流式细胞仪, 免疫组化-石蜡切片
更多信息或购买 :
图像
图像 1 :
Novus Biologicals NBP2-47762-0.1mg 图像 1
Immunocytochemistry/Immunofluorescence: Glypican 3 Antibody (GPC3/863) - Azide and BSA Free [NBP2-47762] - Immunofluorescence Analysis of MeOH-fixed HepG2 cells labeling Glypican-3 with Glypican 3 Antibody (GPC3/863) followed by Goat anti-Mouse IgG-CF488 (Green). The nuclear counterstain is Red Dot (Red)
产品信息
品牌 :
Novus
master code :
NBP2-47762
SKU号 :
NBP2-47762.1毫克
产品名称 :
Glypican 3 Antibody (GPC3/863) - Azide and BSA Free
描述 :
The Glypican 3 Antibody (GPC3/863) - Azide and BSA Free from Novus Biologicals is a mouse monoclonal antibody to Glypican 3. This antibody reacts with human, rat. The Glypican 3 Antibody (GPC3/863) - Azide and BSA Free has been validated for the following applications: Flow Cytometry, Immunohistochemistry, Immunocytochemistry/Immunofluorescence, Immunohistochemistry-Paraffin, Immunofluorescence, CyTOF-ready.
靶标 :
Glypican 3
类别 :
一抗
单位尺寸 :
0.1毫克
缓冲液 :
10 mM PBS
克隆性 :
单克隆
克隆 :
GPC3/863
浓度 :
1.0毫克/毫升
共轭标签 :
未共轭
宿主 :
小鼠
免疫原 :
Recombinant full-length human Glypican 3 protein
抗体亚型 :
IgG1 Kappa
纯度 :
蛋白质A或G纯化
物种 :
人类, 大鼠
特异性 :
Glypican-3 (GPC3) is a glycosylphospatidyl inositol-anchored membrane protein, which may also be found in a secreted form. Anti-GPC3 has been identified as a useful tumor marker for the diagnosis of hepatocellular carcinoma (HCC), hepatoblastoma, melanoma, testicular germ cell tumors, and Wilm s tumor. In patients with HCC, GPC3 is overexpressed in neoplastic liver tissue and elevated in serum, but is undetectable in normal liver, benign liver, and the serum of healthy donors. GPC3 expression is also found to be higher in HCC liver tissue than in cirrhotic liver or liver with focal lesions such as dysplastic nodules and areas of hepatic adenoma (HA) with malignant transformation. In the context of testicular germ cell tumors, GPC3 expression is up regulated in certain histologic subtypes, specifically yolk sac tumors and choriocarcinoma. A high level of GPC3 expression is also found in some types of embryonal tumors, such as Wilm s tumor and hepatoblastoma, with a low or undetectable expression in normal adjacent tissue. In patients with thyroid cancer, expression of GPC3 is dramatically enhanced in certain types of cancers: 100% in follicular carcinoma and 70% in papillary carcinoma. Expression of GPC3 in follicular carcinoma is significantly higher than that of follicular adenoma. In contrast, GPC3 is not expressed in anaplastic carcinoma.
理论上的分子量 :
67 kDa
基因符号 :
GPC3
catalog number base :
NBP2-47762
应用 :
Flow Cytometry, Immunohistochemistry, Immunocytochemistry/Immunofluorescence, Immunohistochemistry-Paraffin, Immunofluorescence, CyTOF-ready
美元2021 :
349
美元2022 :
349美元
atl names :
DGSX, glypican 3, glypican proteoglycan 3, glypican-3, GTR2-2, heparan sulphate proteoglycan, Intestinal protein OCI-5, MXR7, OCI5, OCI-5, secreted glypican-3, SGB, SGBS, SGBS1SDYS
储存 :
Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.
更多信息或购买 :
公司信息
Novus Biologicals
8100 Southpark Way, A-8
Littleton, CO 80120
technical@novusbio.com
https://www.novusbio.com
1-888-506-6887 303-730-1950
公司总部: 美国
Novus Biologicals的任务是开发最先进的新产品及市场行销来加速生物科研的新发现。藉由高效率的组织分工,Novus Biologicals建立了一个将生物学术团体的成果快速商品化的平台。我们的产品除了附有详细的产品资讯外,Novus Biologicals更提供完整的技术支援及服务。利用快速有效的市场通路以便迅速提供所有的科研学者最先进的研究试剂,Novus Biologicals扮演市场上重要的角色。