| 出版应用/物种/样本/稀释 | 参考文献 |
|---|
- 免疫组化; 人类; 图 1d
- 免疫印迹; 人类; 图 1a
| Vazquez Iglesias L, Barcia Castro L, Rodríguez Quiroga M, Páez de la Cadena M, Rodríguez Berrocal J, Cordero O. Surface expression marker profile in colon cancer cell lines and sphere-derived cells suggests complexity in CD26+ cancer stem cells subsets. Biol Open. 2019;8: pubmed 出版商 |
| Wang B, Chen Q, Cao Y, Ma X, Yin C, Jia Y, et al. LGR5 Is a Gastric Cancer Stem Cell Marker Associated with Stemness and the EMT Signature Genes NANOG, NANOGP8, PRRX1, TWIST1, and BMI1. PLoS ONE. 2016;11:e0168904 pubmed 出版商 |
- 免疫细胞化学; 人类; 图 s1b
- 免疫组化; 人类; 图 s5
| Chen H, Wei Z, Sun J, Bhattacharya A, Savage D, Serda R, et al. A recellularized human colon model identifies cancer driver genes. Nat Biotechnol. 2016;34:845-51 pubmed 出版商 |
- 免疫印迹; African green monkey; 1:2000; 图 1
- 免疫印迹; 人类; 1:2000; 图 1
- 免疫印迹; 仓鼠; 1:2000; 图 1
- 免疫印迹; 小鼠; 1:2000; 图 1
| Alizadeh Navaei R, Rafiei A, Abedian Kenari S, Asgarian Omran H, Valadan R, Hedayatizadeh Omran A. Comparison of leucine-rich repeat-containing G protein-coupled receptor 5 expression in different cancer and normal cell lines. Biomed Rep. 2016;5:130-132 pubmed |
- 免疫组化-石蜡切片; 人类; 1:300; 图 s2
| Shaikh L, Zhou J, Teo A, Garg S, Neogi S, Figg N, et al. LGR5 Activates Noncanonical Wnt Signaling and Inhibits Aldosterone Production in the Human Adrenal. J Clin Endocrinol Metab. 2015;100:E836-44 pubmed 出版商 |
| Sharon C, Baranwal S, Patel N, Rodriguez Agudo D, Pandak W, Majumdar A, et al. Inhibition of insulin-like growth factor receptor/AKT/mammalian target of rapamycin axis targets colorectal cancer stem cells by attenuating mevalonate-isoprenoid pathway in vitro and in vivo. Oncotarget. 2015;6:15332-47 pubmed |
- 免疫组化-石蜡切片; 人类; 1:100; 图 5
- 免疫印迹; 人类; 1:500; 图 3d
| Hsu H, Liu Y, Tseng K, Yang T, Yeh C, You J, et al. CBB1003, a lysine-specific demethylase 1 inhibitor, suppresses colorectal cancer cells growth through down-regulation of leucine-rich repeat-containing G-protein-coupled receptor 5 expression. J Cancer Res Clin Oncol. 2015;141:11-21 pubmed 出版商 |
| Hsu H, Liu Y, Tseng K, Tan B, Chen S, Chen H. LGR5 regulates survival through mitochondria-mediated apoptosis and by targeting the Wnt/?-catenin signaling pathway in colorectal cancer cells. Cell Signal. 2014;26:2333-42 pubmed 出版商 |
| Liu R, Moriggl R, Zhang D, Li H, Karns R, Ruan H, et al. Constitutive STAT5 activation regulates Paneth and Paneth-like cells to control Clostridium difficile colitis. Life Sci Alliance. 2019;2: pubmed 出版商 |
| Granofszky N, Lang M, Khare V, Schmid G, Scharl T, Ferk F, et al. Identification of PMN-released Mutagenic Factors in a Co-culture Model for Colitis-associated Cancer. Carcinogenesis. 2017;: pubmed 出版商 |
| Yang Q, Bavi P, Wang J, Roehrl M. Immuno-proteomic discovery of tumor tissue autoantigens identifies olfactomedin 4, CD11b, and integrin alpha-2 as markers of colorectal cancer with liver metastases. J Proteomics. 2017;168:53-65 pubmed 出版商 |
| Patel N, Sharon C, Baranwal S, Boothello R, Desai U, Patel B. Heparan sulfate hexasaccharide selectively inhibits cancer stem cells self-renewal by activating p38 MAP kinase. Oncotarget. 2016;7:84608-84622 pubmed 出版商 |
| Osawa H, Takahashi H, Nishimura J, Ohta K, Haraguchi N, Hata T, et al. Full-length LGR5-positive cells have chemoresistant characteristics in colorectal cancer. Br J Cancer. 2016;114:1251-60 pubmed 出版商 |
| Xi H, Cai A, Wu X, Cui J, Shen W, Bian S, et al. Leucine-rich repeat-containing G-protein-coupled receptor 5 is associated with invasion, metastasis, and could be a potential therapeutic target in human gastric cancer. Br J Cancer. 2014;110:2011-20 pubmed 出版商 |
| Wang J, Guo X, Lui M, Chu P, Yoo J, Chang M, et al. Identification of a distinct small cell population from human bone marrow reveals its multipotency in vivo and in vitro. PLoS ONE. 2014;9:e85112 pubmed 出版商 |
| Jiang N, Zhou J, Chen M, Schiff M, Lee C, Kong K, et al. Postnatal epithelium and mesenchyme stem/progenitor cells in bioengineered amelogenesis and dentinogenesis. Biomaterials. 2014;35:2172-80 pubmed 出版商 |
| Wu C, Xie Y, Gao F, Wang Y, Guo Y, Tian H, et al. Lgr5 expression as stem cell marker in human gastric gland and its relatedness with other putative cancer stem cell markers. Gene. 2013;525:18-25 pubmed 出版商 |
| Pastò A, Marchesi M, Diamantini A, Frasson C, Curtarello M, Lago C, et al. PKH26 staining defines distinct subsets of normal human colon epithelial cells at different maturation stages. PLoS ONE. 2012;7:e43379 pubmed 出版商 |
