抗体

小鼠单克隆抗体IFN丙

20009

100µl

264.00美元

单克隆

小鼠

nonconjugated

3F1E3

免疫印迹, 酶联免疫吸附测定

小鼠单克隆抗体IFN丙

人类;

3F1E3;

小鼠IgG1

100µl

4?;-20?为长期储存

Interferon-? (IFN-?) is a pro-inflammatory cytokine that is central in host resistance to infection. It is mainly produced by natural killer cells and CD4+ and CD8+ T cells, its receptors are found on nearly all cells, where it activates diverse responses that enable potential host cells to prevent invasive infection by bacteria, parasites and viruses. Takayanagi et al. (2000) demonstrated that IFN-? strongly suppresses osteoclastogenesis by interfering with the RANKL (602642)-RANK (603499) signaling pathway. Tsubota et al. (1999) reported that this upregulation in Sjogren syndrome patients may be controlled by interferon-gamma through the activation of transcription factor NFKB

纯化重组片段对应于人IFN-?在大肠杆菌中表达

纯化抗体在PBS含0.03% 叠氮化钠

ELISA: 1/10000;WB: 1/500 - 1/2000

1. Takayanagi, H. et al. Nature 2000. 408: 600-605. ; 2. Tsubota, K. et al. Invest. Ophthal. Vis. Sci. 40: 28-34, 1999.

264.00美元

单克隆抗体

19.3kDa

IFG;IFI