抗体

小鼠单克隆抗体磷酸甘油醛脱氢酶

20035

100µl

198.00美元

单克隆

小鼠

nonconjugated

1.A。 10

免疫印迹, 酶联免疫吸附测定, 免疫组化, 免疫细胞化学

小鼠单克隆抗体磷酸甘油醛脱氢酶

人类

1A10;

小鼠IgG1

100µl

4?;-20?为长期储存

Glyceraldehyde-3-phosphate dehydrogenase (GAPDH) is well known as one of the key enzymes involved in glycolysis. It catalyzes an important energy-yielding step in carbohydrate metabolism, the reversible oxidative phosphorylation of glyceraldehyde-3-phosphate in the presence of inorganic phosphate and nicotinamide adenine dinucleotide (NAD). The enzyme exists as a tetramer of identical chains. Besides its functioning as a glycolytic enzyme in cytoplasm, recent evidence suggest that mammalian GAPDH is also involved in a great number of intracellular proceses such as membrane fusion, microtubule bundling, phosphotransferase activity, nuclear RNA export, DNA replication, and DNA repair. During the last decade a lot of findings appeared concerning the role of GAPDH in different pathologies including prostate cancer progression, programmed neuronal cell death, age- related neuronal diseases, such as Alzheimer’s and Huntington’s disease.

纯化重组片段对应于人磷酸甘油醛脱氢酶在大肠杆菌中表达。;

腹水含0.03% 叠氮化钠

ELISA: 1/10000;WB: 1/500 - 1/2000;IHC: 1/200 - 1/1000;ICC: 1/200 - 1/1000

1. Allen R.W. J. Biol. Chem. 1987.262:649-653. ; 2. Sumner CJ. Ann Neurol 2003.54:6 47-54. ;

198.00美元

单克隆抗体

37kDa

G3PD;GAPD;MGC88685