抗体

小鼠单克隆抗体BLK

20086

100µl

352.00美元

单克隆

小鼠

nonconjugated

9D10B7

免疫印迹, 酶联免疫吸附测定, 免疫组化

小鼠单克隆抗体BLK

人类

9D10B7;

小鼠IgG1

100µl

4?;-20?为长期储存

BLK ( B lymphoid tyrosine kinase), with 505-amino acid protein (about 56KDa), belongs to the Src non-receptor tyrosine kinases family.Different subcellular localizations of Src-family kinases may be important for the regulation of specific cellular processes such as mitogenesis, cytoskeletal organization, and membrane trafficking.Blk is expressed exclusively by B lymphocytes and it is thought to function in a signal transductory pathway specific to this lineage. B lymphoid expression of an active Blk mutant caused proliferation of B progenitor cells and enhanced responsiveness of these cells to interleukin 7. Thus, sustained activation of Blk induces responses normally associated with the pre-BCR.

Purified recombinant fragment of BLK expressed in E. Coli.

腹水含0.03% 叠氮化钠

ELISA: 1/10000;WB: 1/500 - 1/2000;IHC: 1/200 - 1/1000

1. Theresa Tretter, Ashley E. Ross, Dominic I. Dordai. J. Exp. Med., Dec 2003; 198: 1863. ;

352.00美元

单克隆抗体

MGC10442