抗体

小鼠单克隆抗体FGFR4

20145

100µl

308.00美元

单克隆

小鼠

nonconjugated

4H2B10B2

免疫印迹, 酶联免疫吸附测定, 免疫组化

小鼠单克隆抗体FGFR4

人类

4H2B10B2;

小鼠IgG1

100µl

4?;-20?为长期储存

FGFR4 (fibroblast growth factor receptor 4) is part of a family of fibroblast growth factor receptors that mediate the biological functions of specific growth factors. There are four members of the FGF receptor family: FGFR-1 (flg), FGFR-2 (bek, KGFR), FGFR-3 and FGFR-4. Each receptor contains an extracellular ligand binding domain, a transmembrane domain and a cytoplasmic kinase domain. Following ligand binding and dimerization, the receptors are phosphorylated at specific tyrosine residues. These receptor proteins play a role in important processes such as cell division, regulating cell growth and maturation, formation of blood vessels, wound healing, and embryo development. Although specific functions of FGFR4 remain unclear, studies indicate that the gene is involved in muscle development and the maturation of bone cells in the skull. FGFR4 may also play a role in the development and maintenance of specialized cells (called foveal cones) in the light-sensitive layer (the retina) at the back of the eye.

Purified recombinant fragment of FGFR4 expressed in E. Coli.

腹水含0.03% 叠氮化钠

ELISA: 1/10000;WB: 1/500 - 1/2000;IHC: 1/200 - 1/1000

1. Cell Metab. 2005, Oct, 2(4): 209-10. ; 2. Mol Endocrinol. 2006, Nov, 20(11): 2965-75. ;

308.00美元

单克隆抗体

88kDa

TKF;JTK2;CD334;MGC20292