抗体

小鼠单克隆抗体IFN丙

20160

100µl

308.00美元

单克隆

小鼠

nonconjugated

1B1A4

免疫印迹, 酶联免疫吸附测定

小鼠单克隆抗体IFN丙

人类

1B1A4;

小鼠IgG1

100µl

4?;-20?为长期储存

IFN-gamma (interferon, gamma) is an antiviral and antiparasitic agent produced by CD4+/CD8+ lymphocytes and natural killer cells that undergo activation by antigens, mitogens or alloantigens. It is a pleiotropic cytokine involved in the regulation of nearly all phases of immune and inflammatory responses, including the activation, growth and differentiation of T cell, B cells, macrophages, NK cells and other cell types such as endothelial cells and fibroblasts. The active form of IFN-G is a homodimer with each subunit containing six helices. The dimeric structure of human IFN-G is stabilized by non-covalent interactions through the interface of the helices. IFN-G translated precursor is 166 amino acids, including the 23 amino acid secretory sequence. It is upregulated by IL2, FGF basic, EGF and downregulated by vitamin D3 or DMN. Multiple forms exist due to variable glycosylation and under non-denaturing conditions due to dimers and tetramers.

Recombinant human IFN-gamma (BioSource company, Cat.No. PHC4033)

纯化抗体在PBS含0.03% 叠氮化钠

ELISA: 1/10000;WB: 1/500 - 1/2000

1. Dean GA. LaVoy A. Burkhard MJ. Vet Immunol Immunopathol. 2004,Jul, 100(1-2):49-59. ; 2. Arens R. Schepers K. Nolte MA. et al. J Exp Med. 2004,Jun 7, 199(11):1595-605. ; 3. Podhorecka M. Dmoszynska A. Rolinski J. Eur J Haematol. 2004,Jul, 73(1):29-35. ;

308.00美元

单克隆抗体

IFG;IFI;IFNG