抗体

小鼠单克隆抗体PAR4

20213

100μl

352.00美元

单克隆

小鼠

nonconjugated

3G9H7

免疫印迹, 酶联免疫吸附测定, 免疫组化

小鼠单克隆抗体PAR4

人类

3G9H7;

小鼠IgG1

100μl

4℃;-20℃为长期储存

Prostate apoptosis response 4 (Par4) is a 38kD protein originally identified as the product of a gene that is upregulated in prostate tumor cells undergoing apoptosis. It is a leucine zipper and death domain containing protein whose levels increase in neurons undergoing apoptosis as a result of trophic factor withdrawal or exposure to oxidative and metabolic insults. Par4 levels are reported to be increased in their lumbar spinal cord specimens further suggesting a role in neuronal degeneration. The tumor suppressor WT1 represses and activates transcription. The loss and/or imbalance of the dual transcriptional activity of WT1 may contribute to Wilms tumor. Par4 is a WT1 interacting protein that also functions as a transcriptional repressor.

Purified recombinant fragment of PAR4(aa1-330) expressed in E. Coli. ;

腹水含0.03% 叠氮化钠

ELISA: 1/10000;WB: 1/500 - 1/2000;IHC: 1/200 - 1/1000

1. J Biol Chem. 2004 Jul 2;279(27):28266-75. ; 2. Exp Hematol. 2004 Jul;32(7):649-56. ; 3. Mol Cell Biol. 2005 Feb;25(3):1146-61. ; 4. Psychiatr Genet. 2006 Oct;16(5):193-6.

352.00美元

单克隆抗体

PAWR