抗体

小鼠单克隆抗体CD10

20257

100μl

308.00美元

单克隆

小鼠

nonconjugated

3G9D10

免疫印迹, 酶联免疫吸附测定, 免疫组化

小鼠单克隆抗体CD10

人类

3G9D10;

小鼠IgG1

100μl

4℃;-20℃为长期储存

CD10(MME): membrane metallo-endopeptidase. This gene encodes a common acute lymphocytic leukemia antigen that is an important cell surface marker in the diagnosis of human acute lymphocytic leukemia (ALL). This protein is present on leukemic cells of pre-B phenotype, which represent 85% of cases of ALL. This protein is not restricted to leukemic cells, however, and is found on a variety of normal tissues. It is a glycoprotein that is particularly abundant in kidney, where it is present on the brush border of proximal tubules and on glomerular epithelium. The protein is a neutral endopeptidase that cleaves peptides at the amino side of hydrophobic residues and inactivates several peptide hormones including glucagon, enkephalins, substance P, neurotensin, oxytocin, and bradykinin. This gene, which encodes a 100-kD type II transmembrane glycoprotein, exists in a single copy of greater than 45 kb. The 5' untranslated region of this gene is alternatively spliced, resulting in four separate mRNA transcripts. The coding region is not affected by alternative splicing.

Purified recombinant fragment of CD10 expressed in E. Coli. ;

腹水含0.03% 叠氮化钠。;

ELISA: 1/10000;WB: 1/500 - 1/2000;IHC: 1/200 - 1/1000

1. Journal of Gastroenterology,1996 Feb.31(1):12-7. ; 2. British Journal of Haematology,1995,89(3):623-6.

308.00美元

单克隆抗体

NEP;CALLA