抗体

小鼠单克隆抗体STAT3

20293

100μl

308.00美元

单克隆

小鼠

nonconjugated

7G3H4

免疫印迹, 酶联免疫吸附测定, 免疫组化

小鼠单克隆抗体STAT3

人类

7G3H4;

小鼠IgG1

100μl

4℃;-20℃为长期储存

STAT3: signal transducer and activator of transcription 3 (acute-phase response factor). The protein encoded by this gene is a member of the STAT protein family. In response to cytokines and growth factors, STAT family members are phosphorylated by the receptor associated kinases, and then form homo- or heterodimers that translocate to the cell nucleus where they act as transcription activators. This protein is activated through phosphorylation in response to various cytokines and growth factors including IFNs, EGF, IL5, IL6, HGF, LIF and BMP2. This protein mediates the expression of a variety of genes in response to cell stimuli, and thus plays a key role in many cellular processes such as cell growth and apoptosis. The small GTPase Rac1 has been shown to bind and regulate the activity of this protein. PIAS3 protein is a specific inhibitor of this protein. Three alternatively spliced transcript variants encoding distinct isoforms have been described.

Purified recombinant fragment of STAT3 expressed in E. Coli. ;

腹水含0.03% 叠氮化钠。;

ELISA: 1/10000;WB: 1/500 - 1/2000;IHC: 1/200 - 1/1000

1. APMIS. 2007 Dec;115(12):1331-43. ; 2. Oncol Rep. 2008 Sep;20(3):597-604.

308.00美元

单克隆抗体

APRF;HIES