产品简要
公司名称 :
湖南远泰生物技术有限公司
产品类型 :
抗体
产品名称 :
小鼠单克隆抗体FGFR4
目录 :
20328
规格 :
100μl
价格 :
308.00美元
克隆性 :
单克隆
宿主 :
小鼠
共轭标签 :
nonconjugated
克隆名称 :
7H1
反应物种 :
人类
应用 :
免疫印迹, 酶联免疫吸附测定, 免疫细胞化学
产品信息
目录 :
20328
标题 :
小鼠单克隆抗体FGFR4
物种 :
人类
克隆 :
7H1;
同种型 :
小鼠IgG1
规格 :
100μl
储存 :
4℃;-20℃为长期储存
描述 :
FGFR4: fibroblast growth factor receptor 4. Entrez Protein NP_002002. It is a member of the fibroblast growth factor receptor family, where amino acid sequence is highly conserved between members and throughout evolution. FGFR family members differ from one another in their ligand affinities and tissue distribution. A full-length representative protein would consist of an extracellular region, composed of three immunoglobulin-like domains, a single hydrophobic membrane-spanning segment and a cytoplasmic tyrosine kinase domain. The extracellular portion of the protein interacts with fibroblast growth factors, setting in motion a cascade of downstream signals, ultimately influencing mitogenesis and differentiation. The genomic organization of this gene, compared to members 1-3, encompasses 18 exons rather than 19 or 20. Although alternative splicing has been observed, there is no evidence that the C-terminal half of the IgIII domain of this protein varies between three alternate forms, as indicated for members 1-3. This particular family member preferentially binds acidic fibroblast growth factor and, although its specific function is unknown, it is overexpressed in gynecological tumor samples, suggesting a role in breast and ovarian tumorigenesis.
免疫原 :
Purified recombinant extracellular fragment of human FGFR4 fused with hIgGFc tag expressed in HEK293 cell line.
配方 :
腹水含0.03% 叠氮化钠。;
应用 :
ELISA: 1/10000;WB: 1/500 - 1/2000;ICC: 1/200 - 1/1000
参考文献 :
1. Br J Cancer. 2006 Jun 19;94(12):1879-86. ; 2. Diabetes. 2007 Oct;56(10):2501-10.
标价(美元) :
308.00美元
类型 :
单克隆抗体
分子量 :
87.9kDa
别名 :
TKF;JTK2;CD334
公司信息
湖南远泰生物技术有限公司
湖南望城湖南出版科技园2#楼
info@promab.com
www.promab.com.cn
731-88388787
公司总部: 美国