湖南远泰生物技术有限公司

抗体

小鼠单克隆抗体MYL3

20342

100μl

286.00美元

单克隆

小鼠

3F8;

免疫印迹, 酶联免疫吸附测定, 免疫组化

20342

小鼠单克隆抗体MYL3

人类

3F8;

小鼠IgG1

100μl

4℃;-20℃为长期储存

Myosins are a large superfamily of motor proteins that move along actin filaments, while hydrolyzing ATP. Myosin is the major component of thick muscle filaments, and is a long asymmetric molecule containing a globular head and a long tail. The molecule consists of two heavy chains and four light chains. Activation of smooth and cardiac muscle primarily involves pathways which increase calcium and myosin phosphorylation resulting in contraction. Myosin light chain phosphatase acts to regulate muscle contraction by dephosphorylating activated myosin light chain. MYL3 encodes myosin light chain 3, an alkali light chain also referred to in the literature as both the ventricular isoform and the slow skeletal muscle isoform. Human myosin light chain has clinical application as a cardiac marker. Mutations in MYL3 have been identified as a cause of mid-left ventricular chamber type hypertrophic cardiomyopathy.

Purified recombinant fragment of MYL3 expressed in E. Coli.

腹水含0.03% 叠氮化钠

ELISA: 1/10000;WB: 1/500 - 1/2000;IHC: 1/200 - 1/1000

1. Xie B, et al. Biophys Chem. 2003 Oct 1;106(1):57-66. ; 2. Haase H, et al. FASEB J. 2006 May;20(7):865-73.

286.00美元

单克隆抗体

22kDa

CMH8;VLC1;MLC1V;MLC1SB