抗体

小鼠单克隆抗体FGFR1

20359

100μl

308.00美元

单克隆

小鼠

nonconjugated

3D4F7

免疫印迹, 酶联免疫吸附测定

小鼠单克隆抗体FGFR1

人类

3D4F7;

小鼠IgG2b

100μl

4℃;-20℃为长期储存

Fibroblast growth factor receptor 1 (FGFR1), also known as basic fibroblast growth factor receptor 1, fms-related tyrosine kinase-2 / Pfeiffer syndrome, and CD331, is a receptor tyrosine kinase whose ligands are specific members of the fibroblast growth factor family. FGFR1 has been shown to be associated with Pfeiffer syndrome. It is a member of the fibroblast growth factor receptor (FGFR) family, where amino acid sequence is highly conserved between members and throughout evolution. FGFR family members differ from one another in their ligand affinities and tissue distribution. A full-length representative protein consists of an extracellular region, composed of three immunoglobulin-like domains, a single hydrophobic membrane-spanning segment and a cytoplasmic tyrosine kinase domain. The extracellular portion of the protein interacts with fibroblast growth factors, setting in motion a cascade of downstream signals, ultimately influencing mitogenesis and differentiation. This particular family member binds both acidic and basic fibroblast growth factors and is involved in limb induction.

Purified recombinant extracellular fragment of human FGFR1 (aa22-376) fused with hIgGFc tag expressed in HEK293 cells.

腹水含0.03% 叠氮化钠

ELISA: 1/10000;WB: 1/500 - 1/2000

1. J Biol Chem. 2004 Jul 9;279(28):29325-35. ; 2. Arterioscler Thromb Vasc Biol. 2005 May;25(5):944-9. ; 3. Breast Cancer Res. 2007;9(2):R23.

308.00美元

单克隆抗体

92kDa

CEK;FLG;OGD;FLT2;KAL2;BFGFR;CD331;FGFBR;HBGFR