抗体

小鼠单克隆抗体FABP2

20416

100μl

308.00美元

单克隆

小鼠

nonconjugated

9A9B7B3

免疫印迹, 酶联免疫吸附测定, 免疫组化, 免疫细胞化学, 流式细胞仪

小鼠单克隆抗体FABP2

人类

9A9B7B3;

小鼠IgG1

100μl

4℃;-20℃为长期储存

The intracellular fatty acid-binding proteins (FABPs) belong to a multigene family with nearly twenty identified members. FABPs are divided into at least three distinct types, namely the hepatic-, intestinal- and cardiac-type. They form 14-15 kDa proteins and are thought to participate in the uptake, intracellular metabolism and/or transport of long-chain fatty acids. They may also be responsible in the modulation of cell growth and proliferation. Intestinal fatty acid-binding protein 2 gene contains four exons and is an abundant cytosolic protein in small intestine epithelial cells. This gene has a polymorphism at codon 54 that identified an alanine-encoding allele and a threonine-encoding allele. Thr-54 protein is associated with increased fat oxidation and insulin resistance. Genetic variation in FABP2 may thus contribute to interindividual variation in the response of plasma lipoproteins to different dietary fibres, but the mechanism does not appear to be related to increases in fecal bile acid secretion.

纯化重组片段对应于人FABP2在大肠杆菌中表达

腹水含0.03% 叠氮化钠

ELISA: 1/10000;WB: 1/500 - 1/2000;IHC: 1/200 - 1/1000;ICC: 1/200 - 1/1000;FCM: 1/200 - 1/400

1. Yamada, K. et al. (1997) Diabetologia. 40(6):706-10 ; 2. Georgopoulos, A. et al. (2000)85(9):3155-60 ; 3. Kim, CH. et al. (2001) Metabolism. 50(4):473-6 ; 4. Fisher, E. et al. (2006) Horm Metab Res. 38(5):341-5

308.00美元

单克隆抗体

15kDa

FABPI;I-FABP;MGC133132;FABP2