抗体

小鼠单克隆抗体CD86

30107

100μl

308.00美元

单克隆

小鼠

nonconjugated

1.B。 3

免疫印迹, 酶联免疫吸附测定

小鼠单克隆抗体CD86

人类

1B3;

小鼠IgG1

100μl

4℃;-20℃为长期储存

This gene encodes a type I membrane protein that is a member of the immunoglobulin superfamily. This protein is expressed by antigen-presenting cells, and it is the ligand for two proteins at the cell surface of T cells, CD28 antigen and cytotoxic T-lymphocyte-associated protein 4. Binding of this protein with CD28 antigen is a costimulatory signal for activation of the T-cell. Binding of this protein with cytotoxic T-lymphocyte-associated protein 4 negatively regulates T-cell activation and diminishes the immune response. Alternative splicing results in two transcript variants encoding different isoforms. Additional transcript variants have been described, but their full-length sequences have not been determined.Tissue specificity: Expressed by activated B-lymphocytes and monocytes.

纯化重组片段对应于人CD86在大肠杆菌中表达

腹水含0.03% 叠氮化钠

ELISA: 1/10000;WB: 1/500 - 1/2000

1. Clin Exp Allergy. 2009 Dec;39(12):1852-6. ; 2. Am J Hum Genet. 2009 Nov;85(5):628-42. ; 3. Immunology. 2009 Nov;128(3):334-41.

308.00美元

单克隆抗体

52kDa

B70;B7-2;LAB72;CD28LG2;MGC34413;CD86