抗体

小鼠单克隆抗体PAX8

30118

100μl

308.00美元

单克隆

小鼠

nonconjugated

2D4

免疫印迹, 酶联免疫吸附测定

小鼠单克隆抗体PAX8

人类

2D4;

小鼠IgG1

100μl

4℃;-20℃为长期储存

This gene encodes a member of the paired box (PAX) family of transcription factors. Members of this gene family typically encode proteins that contain a paired box domain, an octapeptide, and a paired-type homeodomain. This nuclear protein is involved in thyroid follicular cell development and expression of thyroid-specific genes. Mutations in this gene have been associated with thyroid dysgenesis, thyroid follicular carcinomas and atypical follicular thyroid adenomas.Tissue specificity: Expressed in the excretory system, thyroid gland and Wilms tumors.ABCAM: This protein is a member of the paired box (PAX) family of transcription factors, typically containing a paired box domain, an octapeptide, and a paired-type homeodomain. This family plays critical roles during fetal development and cancer growth. The specific function of the PAX8 is unknown but it may involve kidney cell differentiation, thyroid development, or thyroid dysgenesis. Alternative splicing in the gene by inclusion or exclusion of exons 7 and/or 8 has produced several known products but the biological significance of the variants is unknown. Several other splice variants have been proposed but the full nature of these products has not been described. Pax8 is also a marker of otic progenitor cells.

纯化重组片段对应于人PAX8在大肠杆菌中表达

腹水含0.03% 叠氮化钠

ELISA: 1/10000;WB: 1/500 - 1/2000

1. Thyroid. 2009 Jan;19(1):61-8. ; 2. Cancer Genet Cytogenet. 2010 Jan 1;196(1):7-13. ; 3. Cancer Cytopathol. 2010 Oct 25;118(5):298-302.

308.00美元

单克隆抗体

60kDa

PAX8