抗体

小鼠单克隆抗体IGF2BP3

30129

100μl

308.00美元

单克隆

小鼠

nonconjugated

#8F11

免疫印迹, 酶联免疫吸附测定, 免疫组化

小鼠单克隆抗体IGF2BP3

人类

8F11;

小鼠IgG1

100μl

4℃;-20℃为长期储存

The protein encoded by this gene is primarily found in the nucleolus, where it can bind to the 5' UTR of the insulin-like growth factor II leader 3 mRNA and may repress translation of insulin-like growth factor II during late development. The encoded protein contains several KH domains, which are important in RNA binding and are known to be involved in RNA synthesis and metabolism.Tissue specificity: Expressed in fetal liver, fetal lung, fetal kidney, fetal thymus, fetal placenta, fetal follicles of ovary and gonocytes of testis, growing oocytes, spermatogonia and semen (at protein level). Expressed in cervix adenocarcinoma, in testicular, pancreatic and renal-cell carcinomas (at protein level). Expressed ubiquitously during fetal development at 8 and 14 weeks of gestation. Expressed in ovary, testis, brain, placenta, pancreatic cancer tissues and pancreatic cancer cell lines .IMP-3 is a marker for carcinomas and high-grade dysplastic lesions of pancreatic ductal epithelium.

纯化重组片段对应于人IGF2BP3在大肠杆菌中表达

腹水含0.03% 叠氮化钠

ELISA: 1/10000;WB: 1/500 - 1/2000;IHC: 1/200 - 1/1000

1. Clin Cancer Res. 2008 Mar 15;14(6):1701-6. ; 2. Hepatology. 2008 Oct;48(4):1118-27.

308.00美元

单克隆抗体

69kDa

CT98;IMP3;KOC1;IMP-3;VICKZ3;DKFZp686F1078;IGF2BP3