抗体

小鼠单克隆抗体缺氧诱导因子1A

30195

100μl

341.00美元

单克隆

小鼠

nonconjugated

1.A。 3

人类, 小鼠

免疫印迹, 酶联免疫吸附测定, 免疫组化, 免疫细胞化学

小鼠单克隆抗体缺氧诱导因子1A

Human; Mouse; Monkey

1A3;

小鼠IgG1

100μl

4℃;-20℃为长期储存

Hypoxia-inducible factor-1 (HIF1) is a transcription factor found in mammalian cells cultured under reduced oxygen tension that plays an essential role in cellular and systemic homeostatic responses to hypoxia. HIF1 is a heterodimer composed of an alpha subunit and a beta subunit. The beta subunit has been identified as the aryl hydrocarbon receptor nuclear translocator (ARNT). This gene encodes the alpha subunit of HIF-1. Overexpression of a natural antisense transcript (aHIF) of this gene has been shown to be associated with nonpapillary renal carcinomas. Two alternative transcripts encoding different isoforms have been identified. (provided by RefSeq) Tissue specificity: Expressed in most tissues with highest levels in kidney and heart. Overexpressed in the majority of common human cancers and their metastases, due to the presence of intratumoral hypoxia and as a result of mutations in genes encoding oncoproteins and tumor suppressors.

纯化重组片段对应于人缺氧诱导因子1A在大肠杆菌中表达

腹水含0.03% 叠氮化钠

ELISA: 1/10000;WB: 1/500 - 1/2000;IHC: 1/200 - 1/1000;ICC: 1/200 - 1/1000

1. Int J Radiat Oncol Biol Phys. 2008 Dec 1;72(5):1551-9. ; 2. Eur J Appl Physiol. 2009 Mar;105(4):515-24.

341.00美元

单克隆抗体

120kDa

HIF1;MOP1;PASD8;bHLHe78;HIF-1alpha;HIF1-甲;缺氧诱导因子1A