抗体

小鼠单克隆抗体载脂蛋白B

30214

100μl

341.00美元

单克隆

小鼠

nonconjugated

6G6

免疫印迹, 酶联免疫吸附测定, 免疫细胞化学, 流式细胞仪

小鼠单克隆抗体载脂蛋白B

人类

6G6;

小鼠IgG1

100μl

4℃;-20℃为长期储存

This gene product is the main apolipoprotein of chylomicrons and low density lipoproteins. It occurs in plasma as two main isoforms, apoB-48 and apoB-100: the former is synthesized exclusively in the gut and the latter in the liver. The intestinal and the hepatic forms of apoB are encoded by a single gene from a single, very long mRNA. The two isoforms share a common N-terminal sequence. The shorter apoB-48 protein is produced after RNA editing of the apoB-100 transcript at residue 2180 (CAA->UAA), resulting in the creation of a stop codon, and early translation termination. Mutations in this gene or its regulatory region cause hypobetalipoproteinemia, normotriglyceridemic hypobetalipoproteinemia, and hypercholesterolemia due to ligand-defective apoB, diseases affecting plasma cholesterol and apoB levels.

纯化重组片段对应于人载脂蛋白B在大肠杆菌中表达。;

腹水含0.03% 叠氮化钠

ELISA: 1/10000;WB: 1/500 - 1/2000;ICC: 1/200 - 1/1000;FCM: 1/200 - 1/400

1. Cell Host Microbe. 2008 Dec 11;4(6):555-66. ; 2. Atherosclerosis. 2009 Sep;206(1):17-30.

341.00美元

单克隆抗体

516kDa

FLDB;LDLCQ4