抗体

小鼠单克隆抗体KIT

30259

100μl

341.00美元

单克隆

小鼠

nonconjugated

1C5

免疫印迹, 酶联免疫吸附测定, 免疫组化

小鼠单克隆抗体KIT

人类

1C5;

小鼠IgG1

100μl

4℃;-20℃为长期储存

The c-Kit proto-oncogene is a member of the receptor tyrosine kinase family and, more specifically, is closely related to the platelet derived growth factor receptor (PDGFR). c-Kit, the normal cellular homolog of the HZ4-feline sarcoma virus transforming gene (v-Kit), encodes a transmembrane receptor. c-Kit regulates a variety of biological responses including chemotaxis, cell prolif- eration, apoptosis and adhesion. c-Kit is also identical with the product of the W locus in mice and, as such, is integral to the development of mast cells and hematopoiesis. The ligand for the c-Kit receptor (KL) has been identified and is encoded at the murine steel (SI) locus. Kit is the human homolog of the proto- oncogene c-Kit. Mutations in Kit are integral for tumor growth and progression in various cancers.

纯化重组片段对应于人KIT在大肠杆菌中表达。;

腹水含0.03% 叠氮化钠

ELISA: 1/10000;WB: 1/500 - 1/2000;IHC: 1/200 - 1/1000

1. Curr Hematol Malig Rep. 2009 Apr;4(2):77-82. ; 2. Georgian Med News. 2010 Mar;(180):13-9. ;

341.00美元

单克隆抗体

145kDa

PBT;SCFR;C-kit;CD117