抗体

小鼠单克隆抗体UBB

30317

0.1毫克

341.00美元

单克隆

小鼠

nonconjugated

3C1.2

免疫印迹, 酶联免疫吸附测定, 流式细胞仪

小鼠单克隆抗体UBB

人类

3C12;

小鼠IgG1

0.1毫克

4℃;-20℃为长期储存

This gene encodes ubiquitin, one of the most conserved proteins known. Ubiquitin is required for ATP-dependent, nonlysosomal intracellular protein degradation of abnormal proteins and normal proteins with a rapid turnover. Ubiquitin is covalently bound to proteins to be degraded, and presumably labels these proteins for degradation. Ubiquitin also binds to histone H2A in actively transcribed regions but does not cause histone H2A degradation, suggesting that ubiquitin is also involved in regulation of gene expression. This gene consists of three direct repeats of the ubiquitin coding sequence with no spacer sequence. Consequently, the protein is expressed as a polyubiquitin precursor with a final amino acid after the last repeat. Aberrant form of this protein has been noticed in patients with Alzheimer's and Down syndrome.

纯化重组片段对应于人UBB在大肠杆菌中表达。;

Purified antibody in PBS with 0.05% sodium azide

ELISA: 1/10000;WB: 1/500 - 1/2000;FCM: 1/200 - 1/400

1. Science. 2009 Aug 14;325(5942):834-40. ; 2. Biochem Soc Trans. 2009 Oct;37(Pt 5):937-53. ;

341.00美元

单克隆抗体

26kDa

UBC;泛素蛋白A52残基核糖体蛋白融合产物1;RPS27A