抗体

小鼠单克隆抗体PTPN11

30409

0.1毫克

341.00美元

单克隆

小鼠

nonconjugated

6D9

免疫印迹, 酶联免疫吸附测定, 免疫组化, 免疫细胞化学, 流式细胞仪

小鼠单克隆抗体PTPN11

人类;

6D9;

小鼠IgG1

0.1毫克

4℃;-20℃为长期储存

The protein encoded by this gene is a member of the protein tyrosine phosphatase (PTP) family. PTPs are known to be signaling molecules that regulate a variety of cellular processes including cell growth, differentiation, mitotic cycle, and oncogenic transformation. This PTP contains two tandem Src homology-2 domains, which function as phospho-tyrosine binding domains and mediate the interaction of this PTP with its substrates. This PTP is widely expressed in most tissues and plays a regulatory role in various cell signaling events that are important for a diversity of cell functions, such as mitogenic activation, metabolic control, transcription regulation, and cell migration. Mutations in this gene are a cause of Noonan syndrome as well as acute myeloid leukemia. Two transcript variants encoding different isoforms have been found for this gene.

纯化重组片段对应于人PTPN11(AA: 263-329)在大肠杆菌中表达

Purified antibody in PBS with 0.05% sodium azide

ELISA: 1/10000;WB: 1/500 - 1/2000;IHC: 1/200 - 1/1000;ICC: 1/200 - 1/1000;FCM: 1/200 - 1/400

1.Blood. 2011 Aug 11;118(6):1504-15. 2.Cancer Cell. 2011 May 17;19(5):629-39.

341.00美元

单克隆抗体

68.4kDa

CFC;NS1;SHP2;BPTP3;PTP2C;PTP-1D;SH-PTP2;SH-PTP3;MGC14433