抗体

小鼠单克隆抗体CD59

30428

0.1毫克

341.00美元

单克隆

小鼠

nonconjugated

8D2B8

免疫印迹, 酶联免疫吸附测定, 免疫组化, 免疫细胞化学, 流式细胞仪

小鼠单克隆抗体CD59

人类;

8D2B8;

小鼠IgG1

0.1毫克

4℃;-20℃为长期储存

This gene encodes a cell surface glycoprotein that regulates complement-mediated cell lysis, and it is involved in lymphocyte signal transduction. This protein is a potent inhibitor of the complement membrane attack complex, whereby it binds complement C8 and/or C9 during the assembly of this complex, thereby inhibiting the incorporation of multiple copies of C9 into the complex, which is necessary for osmolytic pore formation. This protein also plays a role in signal transduction pathways in the activation of T cells. Mutations in this gene cause CD59 deficiency, a disease resulting in hemolytic anemia and thrombosis, and which causes cerebral infarction. Multiple alternatively spliced transcript variants, which encode the same protein, have been identified for this gene. ; ;

纯化重组片段对应于人CD59(AA: 31-111)在大肠杆菌中表达

Purified antibody in PBS with 0.05% sodium azide

ELISA: 1/10000;WB: 1/500 - 1/2000;IHC: 1/200 - 1/1000;ICC: 1/50 -1/200;FCM: 1/200 - 1/400

1.Cell Immunol. 2010;265(2):127-32. ; 2.Chin Med J (Engl). 2009 Sep 20;122(18):2123-8. ;

341.00美元

单克隆抗体

14.2kDa

1F5;EJ16;EJ30;EL32;G344;MIN1;MIN2;MIN3;MIRL;HRF20;MACIF;MEM43;MIC11;MSK21;16.3A5;HRF-20;MAC-免疫沉淀;p18-20