抗体

小鼠单克隆抗体MMP2

30440

0.1毫克

341.00美元

单克隆

小鼠

nonconjugated

4D1E2

免疫印迹, 酶联免疫吸附测定

小鼠单克隆抗体MMP2

人类;

4D1E2;

小鼠IgG1

0.1毫克

4℃;-20℃为长期储存

Proteins of the matrix metalloproteinase (MMP) family are involved in the breakdown of extracellular matrix in normal physiological processes, such as embryonic development, reproduction, and tissue remodeling, as well as in disease processes, such as arthritis and metastasis. Most MMP's are secreted as inactive proproteins which are activated when cleaved by extracellular proteinases. This gene encodes an enzyme which degrades type IV collagen, the major structural component of basement membranes. The enzyme plays a role in endometrial menstrual breakdown, regulation of vascularization and the inflammatory response. Mutations in this gene have been associated with Winchester syndrome and Nodulosis-Arthropathy-Osteolysis (NAO) syndrome. Two transcript variants encoding different isoforms have been found for this gene. ; ;

纯化重组片段对应于人MMP2(AA: 242-396)在大肠杆菌中表达

Purified antibody in PBS with 0.05% sodium azide

ELISA: 1/10000;WB: 1/500 - 1/2000

1.Br J Cancer. 2012 Apr 24;106(9):1495-8. ; 2.Iran J Immunol. 2011 Jun;8(2):120-6. ;

341.00美元

单克隆抗体

73.8kDa

CLG4;MONA;CLG4A;TBE-1;基质金属蛋白酶-II