产品简要
公司名称 :
湖南远泰生物技术有限公司
产品类型 :
抗体
产品名称 :
小鼠单克隆抗体WAS
目录 :
30716
规格 :
0.1毫克
价格 :
341.00美元
克隆性 :
单克隆
宿主 :
小鼠
共轭标签 :
nonconjugated
克隆名称 :
7B10E4
反应物种 :
人类
应用 :
免疫印迹, 酶联免疫吸附测定, 免疫组化, 流式细胞仪
更多信息或购买 :
图像
图像 1 :
Black line: Control Antigen (100 ng); Purple line: Antigen(10ng); Blue line: Antigen (50 ng); Red line: Antigen (100 ng);
图像 2 :
Figure 1: Western blot analysis using WAS mAb against human WAS (AA: 57-170) recombinant protein. (Expected MW is 39 kDa)
图像 3 :
Figure 2: Western blot analysis using WAS mAb against HEK293 (1) and WAS (AA: 57-170)-hIgGFc transfected HEK293 (2) cell lysate.
产品信息
目录 :
30716
标题 :
小鼠单克隆抗体WAS
物种 :
人类;
克隆 :
7B10E4;
同种型 :
小鼠IgG2a
规格 :
0.1毫克
储存 :
4℃;-20℃为长期储存
描述 :
The Wiskott-Aldrich syndrome (WAS) family of proteins share similar domain structure, and are involved in transduction of signals from receptors on the cell surface to the actin cytoskeleton. The presence of a number of different motifs suggests that they are regulated by a number of different stimuli, and interact with multiple proteins. Recent studies have demonstrated that these proteins, directly or indirectly, associate with the small GTPase, Cdc42, known to regulate formation of actin filaments, and the cytoskeletal organizing complex, Arp2/3. Wiskott-Aldrich syndrome is a rare, inherited, X-linked, recessive disease characterized by immune dysregulation and microthrombocytopenia, and is caused by mutations in the WAS gene. The WAS gene product is a cytoplasmic protein, expressed exclusively in hematopoietic cells, which show signalling and cytoskeletal abnormalities in WAS patients. A transcript variant arising as a result of alternative promoter usage, and containing a different 5' UTR sequence, has been described, however, its full-length nature is not known.
免疫原 :
纯化重组片段对应于人WAS(AA: 57-170)在大肠杆菌中表达
配方 :
Purified antibody in PBS with 0.05% sodium azide.
应用 :
ELISA: 1/10000;WB: 1/500 - 1/2000;IHC: 1/200 - 1/1000;FCM: 1/200 - 1/400
参考文献 :
1. Mol Cell Biol. 2012 Aug;32(15):3153-63.; 2. Dis Markers. 2010;29(3-4):157-75.
标价(美元) :
341.00美元
类型 :
单克隆抗体
分子量 :
53kDa
别名 :
THC;IMD2;SCNX;THC1;黄蜂
更多信息或购买 :
公司信息
湖南远泰生物技术有限公司
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