产品简要
公司名称 :
湖南远泰生物技术有限公司
产品类型 :
抗体
产品名称 :
小鼠单克隆抗体GNAS
目录 :
30780
规格 :
0.1毫克
价格 :
341.00美元
克隆性 :
单克隆
宿主 :
小鼠
共轭标签 :
nonconjugated
克隆名称 :
7G6G5
反应物种 :
人类
应用 :
免疫印迹, 酶联免疫吸附测定, 免疫组化, 免疫细胞化学, 流式细胞仪
更多信息或购买 :
图像
图像 1 :
Figure 1:Black line: Control Antigen (100 ng); Purple line: Antigen(10ng); Blue line: Antigen (50 ng); Red line: Antigen (100 ng);
图像 2 :
Figure 2:Western blot analysis using GNAS mAb against human GNAS (AA: 42-188) recombinant protein. (Expected MW is 42.8 kDa)
图像 3 :
Figure 3:Western blot analysis using GNAS mAb against HEK293 (1) and GNAS (AA: 42-188)-hIgGFc transfected HEK293 (2) cell lysate.
产品信息
目录 :
30780
标题 :
小鼠单克隆抗体GNAS
物种 :
人类;
克隆 :
7G6G5;
同种型 :
小鼠IgG1
规格 :
0.1毫克
储存 :
4℃;-20℃为长期储存
描述 :
This locus has a highly complex imprinted expression pattern. It gives rise to maternally, paternally, and biallelically expressed transcripts that are derived from four alternative promoters and 5' exons. Some transcripts contain a differentially methylated region (DMR) at their 5' exons, and this DMR is commonly found in imprinted genes and correlates with transcript expression. An antisense transcript is produced from an overlapping locus on the opposite strand. One of the transcripts produced from this locus, and the antisense transcript, are paternally expressed noncoding RNAs, and may regulate imprinting in this region. In addition, one of the transcripts contains a second overlapping ORF, which encodes a structurally unrelated protein - Alex. Alternative splicing of downstream exons is also observed, which results in different forms of the stimulatory G-protein alpha subunit, a key element of the classical signal transduction pathway linking receptor-ligand interactions with the activation of adenylyl cyclase and a variety of cellular reponses. Multiple transcript variants encoding different isoforms have been found for this gene. Mutations in this gene result in pseudohypoparathyroidism type 1a, pseudohypoparathyroidism type 1b, Albright hereditary osteodystrophy, pseudopseudohypoparathyroidism, McCune-Albright syndrome, progressive osseus heteroplasia, polyostotic fibrous dysplasia of bone, and some pituitary tumors. [provided by RefSeq, Aug 2012];
免疫原 :
纯化重组片段对应于人GNAS(AA: 42-188)在大肠杆菌中表达
配方 :
Purified antibody in PBS with 0.05% sodium azide
应用 :
ELISA: 1/10000;WB: 1/500 - 1/2000;IHC:;ICC: 1/200 - 1/1000;FCM: 1/200 - 1/400
参考文献 :
Br J Cancer. 2013 Mar 5;108(4):951-8. ; Anticancer Res. 2012 May;32(5):2169-72.;
标价(美元) :
341.00美元
类型 :
单克隆抗体
分子量 :
68kDa
别名 :
AHO;GSA;GSP;POH;GPSA;NESP;GNAS1;PHP1A;PHP1B;PHP1C;C20orf45
更多信息或购买 :
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