产品简要
公司名称 :
ProSci
产品类型 :
抗体
产品名称 :
SIRP甲抗体
目录 :
1125
规格 :
0.02毫克, 0.1毫克
价格 :
79, 315美元
克隆性 :
多克隆
宿主 :
共轭标签 :
nonconjugated
反应物种 :
人类, 小鼠, 大鼠
应用 :
免疫印迹, 酶联免疫吸附测定, 免疫细胞化学
更多信息或购买 :
文章摘录数: 1
出版应用/物种/样品/稀释参考文献
  • 免疫印迹; 小鼠; 图 2b
Shirakabe K, Omura T, Shibagaki Y, Mihara E, Homma K, Kato Y, et al. Mechanistic insights into ectodomain shedding: susceptibility of CADM1 adhesion molecule is determined by alternative splicing and O-glycosylation. Sci Rep. 2017;7:46174 pubmed 出版商
产品信息
目录代码 :
1125
产品名称 :
SIRP甲抗体
宿主物种 :
克隆性 :
多克隆
共轭 :
未共轭
产品类型 :
一抗
规格 :
0.02毫克, 0.1毫克
标价 :
79, 315美元
抗体亚型 :
IgG
交叉活性 :
人类, 小鼠, 大鼠
背景 :
SIRP alpha Antibody: Protein tyrosine phosphatases (PTPases) SHP-1 and SHP-2 are critical regulators in the intracellular signaling pathways that result in cell responses such as mitosis, differentiation, migration, survival, transformation or death. SHP-2 is a signal transducer for several receptor tyrosine kinases and cytokine receptors. A novel SHP-2 associated glycoprotein was recently cloned from human, rat, mouse and cattle by several labs and was designated SIRPalpha, SHPS-1, MyD-1, BIT and p84. SIRPalpha is a new gene family containing at least fifteen members. SIRPalpha is a substrate of many activated tyrosine kinases such as insulin receptor, EGFR, PDGFR and src, and a specific docking protein for SHP-2. SIRPalpha has regulatory effects on cellular responses induced by serum, growth factors, insulin, oncogenes, growth hormones and cell adhesion and plays a general role in different physiological and pathological processes.
别名 :
SIRP alpha Antibody: BIT, MFR, P84, SIRP, MYD-1, SHPS1, CD172A, PTPNS1, BIT, MYD1, Tyrosine-protein phosphatase non-receptor type substrate 1, Brain Ig-like molecule with tyrosine-based activation motifs, SHP substrate 1
免疫原 :
SIRP alpha antibody was raised against a peptide corresponding to 17 amino acids near the carboxy terminus of human SIRP alpha 1.
特异性 :
识别SIRP甲1, 2和3
纯度 :
SIRP alpha Antibody is affinity chromatography purified via peptide column.
缓冲液 :
SIRP alpha Antibody is supplied in PBS containing 0.02% sodium azide.
浓度 :
1毫克/毫升
用途 :
E, 免疫印迹, 免疫细胞化学
应用摘要 :
SIRP alpha antibody can be used for Western blot at 0.5 - 1 g/mL. 75 - 110 kDa bands should be detected. Antibody can also be used for immunocytochemistry starting at 1 g/mL.
储存 :
SIRP alpha antibody can be stored at 4 C for three months and -20 C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
一般参考 :
Kharitonenkov A, et al. Nature 1997;386:181-186.
一般参考 :
Fujioka Y, et al. Mol Cell Biol 1996;16:6887-6899
一般参考 :
Yamao T, et al. Biochem Biophys Res Commun 1997;231:61-67
一般参考 :
Brooke GP, et al. Eur J Immunol 1998;28:1-11
更多信息或购买 :
公司信息
ProSci
12170 Flint Place
Poway, CA 92064
info@prosci-inc.com
www.prosci-inc.com
1-888-513-9525 1-858-513-2638
公司总部: 美国