产品简要
信息索取 :
公司名称 :
ProSci
产品类型 :
抗体
产品名称 :
TLR7抗体
目录 :
3269
规格 :
0.02毫克, 0.1毫克
克隆性 :
多克隆
宿主 :
兔
反应物种 :
人类, 小鼠
应用 :
免疫印迹, 酶联免疫吸附测定, 免疫组化, 免疫细胞化学
更多信息或购买 :
ProSci 产品网页
文章摘录数: 1
已发表的文献中的应用方法／种属／稀释度参考文献
  • 免疫组化; 人类; 1:200
  • 免疫组化; 小鼠; 1:200
  • 免疫印迹; 小鼠; 1:1,000
Qi J, Buzas K, Fan H, Cohen J, Wang K, Mont E, et al. Painful pathways induced by TLR stimulation of dorsal root ganglion neurons. J Immunol. 2011;186:6417-26 pubmed 出版商
产品信息
目录代码 :
3269
产品名称 :
TLR7抗体
宿主物种 :
兔
克隆性 :
多克隆
共轭 :
未共轭
产品类型 :
一抗
规格 :
0.02毫克, 0.1毫克
抗体亚型 :
IgG
交叉活性 :
人类, 小鼠
背景 :
TLR7 Antibody: Toll-like receptors (TLRs) are signaling molecules that recognize different microbial products during infection and serve as an important link between the innate and adaptive immune responses. These proteins act through adaptor molecules such as MyD88 and TIRAP to activate various kinases and transcription factors. TLR7, like TLRs 3, 8, and 9, is localized in intracellular acidic compartments such as the phagolysosome and will recognize some single-stranded RNA viruses such as vesicular stomatitis virus (VSV) and influenza virus. Activation of TLR7 by VSV results in stimulation of the immune response including IFNalpha secretion, suggesting the importance of TLR7 in virus recognition.
别名 :
TLR7 Antibody: Toll-like receptor 7
免疫原 :
TLR7 antibody was raised against a peptide corresponding to 14 amino acids near the center of mouse TLR7.
纯度 :
TLR7 Antibody is affinity chromatography purified via peptide column.
缓冲液 :
TLR7 Antibody is supplied in PBS containing 0.02% sodium azide.
浓度 :
1毫克/毫升
用途 :
E, 免疫印迹, 免疫细胞化学
应用摘要 :
TLR7 antibody can be used for detection of TLR7 by Western blot at 0.5 to 2 g/mL. Antibody can also be used for immunocytochemistry starting at 2 g/mL.
储存 :
TLR7 antibody can be stored at 4 C for three months and -20 C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
一般参考 :
Vogel SN, Fitzgerald KA, and Fenton MJ. TLRs: differential adapter utilization by toll-like receptors mediates TLR-specific patterns of gene expression. Mol. Interv. 2003; 3:466-77.
一般参考 :
Takeda K, Kaisho T, and Akira S. Toll-like receptors. Annu. Rev. Immunol. 2003; 21:335-76.
一般参考 :
Janeway CA Jr. and Medzhitov R. Innate immune recognition. Annu. Rev. Immunol. 2002; 20:197-216.
一般参考 :
O’Neill LAJ, Fitzgerald FA, and Bowie AG. The Toll-IL-1 receptor adaptor family grows to five members. Trends in Imm. 2003; 24:286-9.
更多信息或购买 :
ProSci 产品网页
公司信息
ProSci
12170 Flint Place
Poway, CA 92064
info@prosci-inc.com
www.prosci-inc.com
1-888-513-9525 1-858-513-2638
公司总部: 美国