产品简要
公司名称 :
ProSci
产品类型 :
抗体
产品名称 :
Toll样受体3抗体
目录 :
3643
规格 :
0.02毫克, 0.1毫克
价格 :
79, 315美元
克隆性 :
多克隆
宿主 :
共轭标签 :
nonconjugated
反应物种 :
人类, 小鼠
应用 :
免疫印迹, 酶联免疫吸附测定, 免疫组化, 免疫细胞化学
更多信息或购买 :
文章摘录数: 2
出版应用/物种/样品/稀释参考文献
  • 免疫组化; 人类; 1:200
  • 免疫组化; 小鼠; 1:200
  • 免疫印迹; 小鼠; 1:1,000
Qi J, Buzas K, Fan H, Cohen J, Wang K, Mont E, et al. Painful pathways induced by TLR stimulation of dorsal root ganglion neurons. J Immunol. 2011;186:6417-26 pubmed 出版商
Menendez D, Lowe J, Snipe J, Resnick M. Ligand dependent restoration of human TLR3 signaling and death in p53 mutant cells. Oncotarget. 2016;7:61630-61642 pubmed 出版商
产品信息
目录代码 :
3643
产品名称 :
Toll样受体3抗体
宿主物种 :
克隆性 :
多克隆
共轭 :
未共轭
产品类型 :
一抗
规格 :
0.02毫克, 0.1毫克
标价 :
79, 315美元
抗体亚型 :
IgG
交叉活性 :
人类, 小鼠
背景 :
TLR3 Antibody: Toll-like receptors (TLRs) are evolutionarily conserved pattern-recognition molecules resembling the toll proteins that mediate antimicrobial responses in Drosophila. These proteins recognize different microbial products during infection and serve as an important link between the innate and adaptive immune responses. The TLRs act through adaptor molecules such as MyD88 and TIRAP to activate various kinases and transcription factors so the organism can respond to potential infection. TLR3 is known to recognize viral double-stranded (ds) RNA, a molecular pattern associated with viral infection. Recently it has been shown to recognize viruses such as Influenza A and West Nile Virus and can mediate entry of at least West Nile Virus.
别名 :
TLR3 Antibody: CD283, IIAE2, Toll-like receptor 3
免疫原 :
TLR3 antibody was raised against a peptide corresponding to 15 amino acids near the carboxy terminus of human TLR3.
纯度 :
TLR3 Antibody is affinity chromatography purified via peptide column.
缓冲液 :
TLR3 Antibody is supplied in PBS containing 0.02% sodium azide.
浓度 :
1毫克/毫升
用途 :
E, 免疫印迹, 免疫细胞化学, IF
应用摘要 :
TLR3 antibody can be used for detection of TLR3 by Western blot at 1 to 2 g/mL. Antibody can also be used for immunocytochemistry starting at 1 g/mL. For immunofluorescence start at 10 g/mL.
储存 :
TLR3 antibody can be stored at 4 C for three months and -20 C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
一般参考 :
Takeda K, Kaisho T, and Akira S. Toll-like receptors. Annu. Rev. Immunol. 2003; 21:335-76.
一般参考 :
Janeway CA Jr. and Medzhitov R. Innate immune recognition. Annu. Rev. Immunol. 2002; 20:197-216.
一般参考 :
McGettrick AF and O’Neill LAJ. The expanding family of MyD88-like adaptors in Toll-like receptor signal transduction. Mol Imm. 2004; 41:577-82.
一般参考 :
Alexopoulou L, Holt AC, Medzhitov R, et al. Recognition of double-stranded RNA and activation of NF- B by Toll-like receptor 3. Nature 2001; 413:732-8.
更多信息或购买 :
公司信息
ProSci
12170 Flint Place
Poway, CA 92064
info@prosci-inc.com
www.prosci-inc.com
1-888-513-9525 1-858-513-2638
公司总部: 美国