Kakimoto Y, Sasaki A, Niioka M, Kawabe N, Osawa M. Myocardial cathepsin D is downregulated in sudden cardiac death. PLoS ONE. 2020;15:e0230375 pubmed 出版商

Horigome Y, Ida Yonemochi H, Waguri S, Shibata S, Endo N, Komatsu M. Loss of autophagy in chondrocytes causes severe growth retardation. Autophagy. 2019;:1-11 pubmed 出版商

Saito T, Kuma A, Sugiura Y, Ichimura Y, Obata M, Kitamura H, et al. Autophagy regulates lipid metabolism through selective turnover of NCoR1. Nat Commun. 2019;10:1567 pubmed 出版商

Gasset Rosa F, Lu S, Yu H, Chen C, Melamed Z, Guo L, et al. Cytoplasmic TDP-43 De-mixing Independent of Stress Granules Drives Inhibition of Nuclear Import, Loss of Nuclear TDP-43, and Cell Death. Neuron. 2019;102:339-357.e7 pubmed 出版商

Carballo Carbajal I, Laguna A, Romero Gimenez J, Cuadros T, Bove J, Martinez Vicente M, et al. Brain tyrosinase overexpression implicates age-dependent neuromelanin production in Parkinson's disease pathogenesis. Nat Commun. 2019;10:973 pubmed 出版商

Viana Huete V, Guillen C, García G, Fernandez S, García Aguilar A, Kahn C, et al. Male Brown Fat-Specific Double Knockout of IGFIR/IR: Atrophy, Mitochondrial Fission Failure, Impaired Thermogenesis, and Obesity. Endocrinology. 2018;159:323-340 pubmed 出版商

Bartolomeo R, Cinque L, De Leonibus C, Forrester A, Salzano A, Monfregola J, et al. mTORC1 hyperactivation arrests bone growth in lysosomal storage disorders by suppressing autophagy. J Clin Invest. 2017;127:3717-3729 pubmed 出版商

Joachim J, Razi M, Judith D, Wirth M, Calamita E, Encheva V, et al. Centriolar Satellites Control GABARAP Ubiquitination and GABARAP-Mediated Autophagy. Curr Biol. 2017;27:2123-2136.e7 pubmed 出版商

Shiba Fukushima K, Ishikawa K, Inoshita T, Izawa N, Takanashi M, Sato S, et al. Evidence that phosphorylated ubiquitin signaling is involved in the etiology of Parkinson's disease. Hum Mol Genet. 2017;26:3172-3185 pubmed 出版商

Wu D, Adamopoulos I. Loss of WDFY3 ameliorates severity of serum transfer-induced arthritis independently of autophagy. Cell Immunol. 2017;316:61-69 pubmed 出版商

Fajardo V, Gamu D, Mitchell A, Bloemberg D, Bombardier E, Chambers P, et al. Sarcolipin deletion exacerbates soleus muscle atrophy and weakness in phospholamban overexpressing mice. PLoS ONE. 2017;12:e0173708 pubmed 出版商

Ho T, Warr M, Adelman E, Lansinger O, Flach J, Verovskaya E, et al. Autophagy maintains the metabolism and function of young and old stem cells. Nature. 2017;543:205-210 pubmed 出版商

Nascimbeni A, Fanin M, Angelini C, Sandri M. Autophagy dysregulation in Danon disease. Cell Death Dis. 2017;8:e2565 pubmed 出版商

Ruf S, Heberle A, Langelaar Makkinje M, Gelino S, Wilkinson D, Gerbeth C, et al. PLK1 (polo like kinase 1) inhibits MTOR complex 1 and promotes autophagy. Autophagy. 2017;13:486-505 pubmed 出版商

Lee M, Sumpter R, Zou Z, Sirasanagandla S, Wei Y, Mishra P, et al. Peroxisomal protein PEX13 functions in selective autophagy. EMBO Rep. 2017;18:48-60 pubmed 出版商

Starobinets H, Ye J, Broz M, Barry K, Goldsmith J, Marsh T, et al. Antitumor adaptive immunity remains intact following inhibition of autophagy and antimalarial treatment. J Clin Invest. 2016;126:4417-4429 pubmed 出版商

Hewitt G, Carroll B, Sarallah R, Correia Melo C, Ogrodnik M, Nelson G, et al. SQSTM1/p62 mediates crosstalk between autophagy and the UPS in DNA repair. Autophagy. 2016;12:1917-1930 pubmed

Vodicka P, Chase K, Iuliano M, Valentine D, Sapp E, Lu B, et al. Effects of Exogenous NUB1 Expression in the Striatum of HDQ175/Q7 Mice. J Huntingtons Dis. 2016;5:163-74 pubmed 出版商

Zhang J, Lachance V, Schaffner A, Li X, Fedick A, Kaye L, et al. A Founder Mutation in VPS11 Causes an Autosomal Recessive Leukoencephalopathy Linked to Autophagic Defects. PLoS Genet. 2016;12:e1005848 pubmed 出版商

Ren H, Elgner F, Jiang B, Himmelsbach K, Medvedev R, Ploen D, et al. The Autophagosomal SNARE Protein Syntaxin 17 Is an Essential Factor for the Hepatitis C Virus Life Cycle. J Virol. 2016;90:5989-6000 pubmed 出版商

Angelini C, Nascimbeni A, Cenacchi G, Tasca E. Lipolysis and lipophagy in lipid storage myopathies. Biochim Biophys Acta. 2016;1862:1367-73 pubmed 出版商

Scotton C, Bovolenta M, Schwartz E, Falzarano M, Martoni E, Passarelli C, et al. Deep RNA profiling identified CLOCK and molecular clock genes as pathophysiological signatures in collagen VI myopathy. J Cell Sci. 2016;129:1671-84 pubmed 出版商

Kenific C, Stehbens S, Goldsmith J, Leidal A, Faure N, Ye J, et al. NBR1 enables autophagy-dependent focal adhesion turnover. J Cell Biol. 2016;212:577-90 pubmed 出版商

Cao L, Qin X, Peterson M, Haller S, Wilson K, Hu N, et al. CARD9 knockout ameliorates myocardial dysfunction associated with high fat diet-induced obesity. J Mol Cell Cardiol. 2016;92:185-95 pubmed 出版商

Puvirajesinghe T, Bertucci F, Jain A, Scerbo P, Belotti E, Audebert S, et al. Identification of p62/SQSTM1 as a component of non-canonical Wnt VANGL2-JNK signalling in breast cancer. Nat Commun. 2016;7:10318 pubmed 出版商

Ruegsegger C, Stucki D, Steiner S, Angliker N, Radecke J, Keller E, et al. Impaired mTORC1-Dependent Expression of Homer-3 Influences SCA1 Pathophysiology. Neuron. 2016;89:129-46 pubmed 出版商

Kaizuka T, Mizushima N. Atg13 Is Essential for Autophagy and Cardiac Development in Mice. Mol Cell Biol. 2016;36:585-95 pubmed 出版商

Pettersen K, Monsen V, HakvÃ¥g Pettersen C, Overland H, Pettersen G, Samdal H, et al. DHA-induced stress response in human colon cancer cells - Focus on oxidative stress and autophagy. Free Radic Biol Med. 2016;90:158-72 pubmed 出版商

Elgner F, Donnerhak C, Ren H, Medvedev R, Schreiber A, Weber L, et al. Characterization of α-taxilin as a novel factor controlling the release of hepatitis C virus. Biochem J. 2016;473:145-55 pubmed 出版商

Bhushan J, Radke J, Perng Y, McAllaster M, Lenschow D, Virgin H, et al. ISG15 Connects Autophagy and IFN-γ-Dependent Control of Toxoplasma gondii Infection in Human Cells. MBio. 2020;11: pubmed 出版商

Goldsmith J, Marsh T, Asthana S, Leidal A, Suresh D, Olshen A, et al. Ribosome profiling reveals a functional role for autophagy in mRNA translational control. Commun Biol. 2020;3:388 pubmed 出版商

Choi I, Zhang Y, Seegobin S, Pruvost M, Wang Q, Purtell K, et al. Microglia clear neuron-released α-synuclein via selective autophagy and prevent neurodegeneration. Nat Commun. 2020;11:1386 pubmed 出版商

Sarraf S, Sideris D, Giagtzoglou N, Ni L, Kankel M, Sen A, et al. PINK1/Parkin Influences Cell Cycle by Sequestering TBK1 at Damaged Mitochondria, Inhibiting Mitosis. Cell Rep. 2019;29:225-235.e5 pubmed 出版商

Yang Y, Willis T, Button R, Strang C, Fu Y, Wen X, et al. Cytoplasmic DAXX drives SQSTM1/p62 phase condensation to activate Nrf2-mediated stress response. Nat Commun. 2019;10:3759 pubmed 出版商

Pasquier A, Vivot K, Erbs E, Spiegelhalter C, Zhang Z, Aubert V, et al. Lysosomal degradation of newly formed insulin granules contributes to β cell failure in diabetes. Nat Commun. 2019;10:3312 pubmed 出版商

Sarkar C, Jones J, Hegdekar N, Thayer J, Kumar A, Faden A, et al. PLA2G4A/cPLA2-mediated lysosomal membrane damage leads to inhibition of autophagy and neurodegeneration after brain trauma. Autophagy. 2019;:1-20 pubmed 出版商

Di Rienzo M, Antonioli M, Fusco C, Liu Y, Mari M, Orhon I, et al. Autophagy induction in atrophic muscle cells requires ULK1 activation by TRIM32 through unanchored K63-linked polyubiquitin chains. Sci Adv. 2019;5:eaau8857 pubmed 出版商

Hoem G, Bowitz Larsen K, Øvervatn A, Brech A, Lamark T, Sjøttem E, et al. The FMRpolyGlycine Protein Mediates Aggregate Formation and Toxicity Independent of the CGG mRNA Hairpin in a Cellular Model for FXTAS. Front Genet. 2019;10:249 pubmed 出版商

Kinsey C, Camolotto S, Boespflug A, Guillen K, Foth M, Truong A, et al. Protective autophagy elicited by RAF→MEK→ERK inhibition suggests a treatment strategy for RAS-driven cancers. Nat Med. 2019;25:620-627 pubmed 出版商

Wang Y, Xiong H, Liu D, Hill C, Ertay A, Li J, et al. Autophagy inhibition specifically promotes epithelial-mesenchymal transition and invasion in RAS-mutated cancer cells. Autophagy. 2019;15:886-899 pubmed 出版商

Birgisdottir A, Mouilleron S, Bhujabal Z, Wirth M, Sjøttem E, Evjen G, et al. Members of the autophagy class III phosphatidylinositol 3-kinase complex I interact with GABARAP and GABARAPL1 via LIR motifs. Autophagy. 2019;15:1333-1355 pubmed 出版商

Garcia D, Hellberg K, Chaix A, Wallace M, Herzig S, Badur M, et al. Genetic Liver-Specific AMPK Activation Protects against Diet-Induced Obesity and NAFLD. Cell Rep. 2019;26:192-208.e6 pubmed 出版商

Sebori R, Kuno A, Hosoda R, Hayashi T, Horio Y. Resveratrol Decreases Oxidative Stress by Restoring Mitophagy and Improves the Pathophysiology of Dystrophin-Deficient mdx Mice. Oxid Med Cell Longev. 2018;2018:9179270 pubmed 出版商

Ogmundsdóttir M, Fock V, Sooman L, Pogenberg V, Dilshat R, Bindesbøll C, et al. A short isoform of ATG7 fails to lipidate LC3/GABARAP. Sci Rep. 2018;8:14391 pubmed 出版商

Battista R, Resnati M, Facchi C, Ruggieri E, Cremasco F, Paradiso F, et al. Autophagy mediates epithelial cancer chemoresistance by reducing p62/SQSTM1 accumulation. PLoS ONE. 2018;13:e0201621 pubmed 出版商

Koyuncu S, Saez I, Lee H, Gutiérrez García R, Pokrzywa W, Fatima A, et al. The ubiquitin ligase UBR5 suppresses proteostasis collapse in pluripotent stem cells from Huntington's disease patients. Nat Commun. 2018;9:2886 pubmed 出版商

Yamada T, Murata D, Adachi Y, Itoh K, Kameoka S, Igarashi A, et al. Mitochondrial Stasis Reveals p62-Mediated Ubiquitination in Parkin-Independent Mitophagy and Mitigates Nonalcoholic Fatty Liver Disease. Cell Metab. 2018;28:588-604.e5 pubmed 出版商

Vincent A, Rosa H, Pabis K, Lawless C, Chen C, Grünewald A, et al. Subcellular origin of mitochondrial DNA deletions in human skeletal muscle. Ann Neurol. 2018;84:289-301 pubmed 出版商

Barutcu S, Girnius N, Vernia S, Davis R. Role of the MAPK/cJun NH2-terminal kinase signaling pathway in starvation-induced autophagy. Autophagy. 2018;14:1586-1595 pubmed 出版商

Fernández A, Sebti S, Wei Y, Zou Z, Shi M, McMillan K, et al. Disruption of the beclin 1-BCL2 autophagy regulatory complex promotes longevity in mice. Nature. 2018;558:136-140 pubmed 出版商

Mitsui S, Otomo A, Nozaki M, Ono S, Sato K, Shirakawa R, et al. Systemic overexpression of SQSTM1/p62 accelerates disease onset in a SOD1H46R-expressing ALS mouse model. Mol Brain. 2018;11:30 pubmed 出版商

McLelland G, Goiran T, Yi W, Dorval G, Chen C, Lauinger N, et al. Mfn2 ubiquitination by PINK1/parkin gates the p97-dependent release of ER from mitochondria to drive mitophagy. elife. 2018;7: pubmed 出版商

Nwadike C, Williamson L, Gallagher L, Guan J, Chan E. AMPK Inhibits ULK1-Dependent Autophagosome Formation and Lysosomal Acidification via Distinct Mechanisms. Mol Cell Biol. 2018;38: pubmed 出版商

Prabakaran T, Bodda C, Krapp C, Zhang B, Christensen M, Sun C, et al. Attenuation of cGAS-STING signaling is mediated by a p62/SQSTM1-dependent autophagy pathway activated by TBK1. EMBO J. 2018;37: pubmed 出版商

Kageyama S, Saito T, Obata M, Koide R, Ichimura Y, Komatsu M. Negative Regulation of the Keap1-Nrf2 Pathway by a p62/Sqstm1 Splicing Variant. Mol Cell Biol. 2018;38: pubmed 出版商

Wallot Hieke N, Verma N, Schlütermann D, Berleth N, Deitersen J, Böhler P, et al. Systematic analysis of ATG13 domain requirements for autophagy induction. Autophagy. 2018;14:743-763 pubmed 出版商

Mishra P, Dauphinee A, Ward C, Sarkar S, Gunawardena A, Manjithaya R. Discovery of pan autophagy inhibitors through a high-throughput screen highlights macroautophagy as an evolutionarily conserved process across 3 eukaryotic kingdoms. Autophagy. 2017;13:1556-1572 pubmed 出版商

Sample A, Zhao B, Qiang L, He Y. Adaptor protein p62 promotes skin tumor growth and metastasis and is induced by UVA radiation. J Biol Chem. 2017;292:14786-14795 pubmed 出版商

Jacquier A, Delorme C, Belotti E, Juntas Morales R, Solé G, Dubourg O, et al. Cryptic amyloidogenic elements in mutant NEFH causing Charcot-Marie-Tooth 2 trigger aggresome formation and neuronal death. Acta Neuropathol Commun. 2017;5:55 pubmed 出版商

McLendon P, Davis G, Gulick J, Singh S, Xu N, Salomonis N, et al. An Unbiased High-Throughput Screen to Identify Novel Effectors That Impact on Cardiomyocyte Aggregate Levels. Circ Res. 2017;121:604-616 pubmed 出版商

Feldmann A, Bekbulat F, Huesmann H, Ulbrich S, Tatzelt J, Behl C, et al. The RAB GTPase RAB18 modulates macroautophagy and proteostasis. Biochem Biophys Res Commun. 2017;486:738-743 pubmed 出版商

Scekic Zahirovic J, Oussini H, Mersmann S, Drenner K, Wagner M, Sun Y, et al. Motor neuron intrinsic and extrinsic mechanisms contribute to the pathogenesis of FUS-associated amyotrophic lateral sclerosis. Acta Neuropathol. 2017;133:887-906 pubmed 出版商

Shimozawa A, Ono M, Takahara D, Tarutani A, Imura S, Masuda Suzukake M, et al. Propagation of pathological ?-synuclein in marmoset brain. Acta Neuropathol Commun. 2017;5:12 pubmed 出版商

Diamanti M, Gupta J, Bennecke M, De Oliveira T, Ramakrishnan M, Braczynski A, et al. IKK? controls ATG16L1 degradation to prevent ER stress during inflammation. J Exp Med. 2017;214:423-437 pubmed 出版商

Yamanaka T, Tosaki A, Miyazaki H, Kurosawa M, Koike M, Uchiyama Y, et al. Differential roles of NF-Y transcription factor in ER chaperone expression and neuronal maintenance in the CNS. Sci Rep. 2016;6:34575 pubmed 出版商

Achour I, Arel Dubeau A, Renaud J, Legrand M, Attard E, Germain M, et al. Oleuropein Prevents Neuronal Death, Mitigates Mitochondrial Superoxide Production and Modulates Autophagy in a Dopaminergic Cellular Model. Int J Mol Sci. 2016;17: pubmed 出版商

Santeford A, Wiley L, Park S, Bamba S, Nakamura R, Gdoura A, et al. Impaired autophagy in macrophages promotes inflammatory eye disease. Autophagy. 2016;12:1876-1885 pubmed

Lim S, Jin L, Jin J, Yang C. Effect of Exendin-4 on Autophagy Clearance in Beta Cell of Rats with Tacrolimus-induced Diabetes Mellitus. Sci Rep. 2016;6:29921 pubmed 出版商

Saito T, Ichimura Y, Taguchi K, Suzuki T, Mizushima T, Takagi K, et al. p62/Sqstm1 promotes malignancy of HCV-positive hepatocellular carcinoma through Nrf2-dependent metabolic reprogramming. Nat Commun. 2016;7:12030 pubmed 出版商

Ra E, Lee T, Won Kim S, Park A, Choi H, Jang I, et al. TRIM31 promotes Atg5/Atg7-independent autophagy in intestinal cells. Nat Commun. 2016;7:11726 pubmed 出版商

Corcelle Termeau E, Vindeløv S, Hämälistö S, Mograbi B, Keldsbo A, Bräsen J, et al. Excess sphingomyelin disturbs ATG9A trafficking and autophagosome closure. Autophagy. 2016;12:833-49 pubmed 出版商

Taneike M, Nishida K, Omiya S, Zarrinpashneh E, Misaka T, Kitazume Taneike R, et al. mTOR Hyperactivation by Ablation of Tuberous Sclerosis Complex 2 in the Mouse Heart Induces Cardiac Dysfunction with the Increased Number of Small Mitochondria Mediated through the Down-Regulation of Autophagy. PLoS ONE. 2016;11:e0152628 pubmed 出版商

Salas E, Roy S, Marsh T, Rubin B, Debnath J. Oxidative pentose phosphate pathway inhibition is a key determinant of antimalarial induced cancer cell death. Oncogene. 2016;35:2913-22 pubmed 出版商

Ruozi G, Bortolotti F, Falcione A, Dal Ferro M, Ukovich L, Macedo A, et al. AAV-mediated in vivo functional selection of tissue-protective factors against ischaemia. Nat Commun. 2015;6:7388 pubmed 出版商

Lenoir O, Jasiek M, Henique C, Guyonnet L, Hartleben B, Bork T, et al. Endothelial cell and podocyte autophagy synergistically protect from diabetes-induced glomerulosclerosis. Autophagy. 2015;11:1130-45 pubmed 出版商

Xu X, Araki K, Li S, Han J, Ye L, Tan W, et al. Autophagy is essential for effector CD8(+) T cell survival and memory formation. Nat Immunol. 2014;15:1152-61 pubmed 出版商

Zhang L, Chen X, Sharma P, Moon M, Sheftel A, Dawood F, et al. HACE1-dependent protein degradation provides cardiac protection in response to haemodynamic stress. Nat Commun. 2014;5:3430 pubmed 出版商