出版应用/物种/样本/稀释 | 参考文献 |
---|
| Jiang Z, Tang Y, Song H, Yang M, Li B, Ni C. miRNA‑342 suppresses renal interstitial fibrosis in diabetic nephropathy by targeting SOX6. Int J Mol Med. 2020;45:45-52 pubmed 出版商
|
| Gao H, Zhang J, Ren X. PD-L1 regulates tumorigenesis and autophagy of ovarian cancer by activating mTORC signaling. Biosci Rep. 2019;39: pubmed 出版商
|
| Zhu B, Ren C, Du K, Zhu H, Ai Y, Kang F, et al. Olean-28,13b-olide 2 plays a role in cisplatin-mediated apoptosis and reverses cisplatin resistance in human lung cancer through multiple signaling pathways. Biochem Pharmacol. 2019;170:113642 pubmed 出版商
|
| Zhong B, Shi D, Wu F, Wang S, Hu H, Cheng C, et al. Dynasore suppresses cell proliferation, migration, and invasion and enhances the antitumor capacity of cisplatin via STAT3 pathway in osteosarcoma. Cell Death Dis. 2019;10:687 pubmed 出版商
|
| Wang K, Zhu T, Zhao R. Filamin A regulates EGFR/ERK/Akt signaling and affects colorectal cancer cell growth and migration. Mol Med Rep. 2019;20:3671-3678 pubmed 出版商
|
| Jin Y, Li Y, Wang X, Yang Y. Secretory leukocyte protease inhibitor suppresses HPV E6-expressing HNSCC progression by mediating NF-κB and Akt pathways. Cancer Cell Int. 2019;19:220 pubmed 出版商
|
| Gao L, Wang Z, Lu D, Huang J, Liu J, Hong L. Paeonol induces cytoprotective autophagy via blocking the Akt/mTOR pathway in ovarian cancer cells. Cell Death Dis. 2019;10:609 pubmed 出版商
|
| Suo L, Chang X, Xu N, Ji H. The Anti-proliferative Activity of GnRH Through Downregulation of the Akt/ERK Pathways in Pancreatic Cancer. Front Endocrinol (Lausanne). 2019;10:370 pubmed 出版商
|
| Ye Z, Zeng Z, Shen Y, Yang Q, Chen D, Chen Z, et al. ODC1 promotes proliferation and mobility via the AKT/GSK3β/β-catenin pathway and modulation of acidotic microenvironment in human hepatocellular carcinoma. Onco Targets Ther. 2019;12:4081-4092 pubmed 出版商
|
| Ortega F, Roefs M, De Miguel Pérez D, Kooijmans S, de Jong O, Sluijter J, et al. Interfering with endolysosomal trafficking enhances release of bioactive exosomes. Nanomedicine. 2019;:102014 pubmed 出版商
|
- 免疫印迹; 小鼠; 图 2c
- 免疫印迹; 人类; 图 6a
| Xu F, Xiao H, Liu R, Yang Y, Zhang M, Chen L, et al. Paeonol Ameliorates Glucose and Lipid Metabolism in Experimental Diabetes by Activating Akt. Front Pharmacol. 2019;10:261 pubmed 出版商
|
- 免疫印迹; 人类; 1:2000; 图 s2a
- 免疫印迹; 小鼠; 1:2000; 图 s2b
| Zhang S, Liu W, Yang Y, Sun K, Li S, Xu H, et al. Tmem30a Deficiency in endothelial cells impairs cell proliferation and angiogenesis. J Cell Sci. 2019;: pubmed 出版商
|
| Chen L, Yang G, Dong H. Everolimus Reverses Palbociclib Resistance in ER+ Human Breast Cancer Cells by Inhibiting Phosphatidylinositol 3-Kinase(PI3K)/Akt/Mammalian Target of Rapamycin (mTOR) Pathway. Med Sci Monit. 2019;25:77-86 pubmed 出版商
|
| Dong F, Ling Q, Ye D, Zhang Z, Shu J, Chen G, et al. TCF7L2 involvement in estradiol- and progesterone-modulated islet and hepatic glucose homeostasis. Sci Rep. 2016;6:24859 pubmed 出版商
|
| Li Y, Zhang M, Li F. LncRNA AY343892 inhibits breast cancer development by positively regulating BRCA1-mediated transcription of PTEN. Histol Histopathol. 2020;:18245 pubmed 出版商
|
| Liu Y, Yang C, Feng X, Qi L, Guo J, Zhu D, et al. Prenatal High-Salt Diet-Induced Metabolic Disorders via Decreasing Peroxisome Proliferator-Activated Receptor Gamma Coactivator 1α in Adult Male Rat Offspring. Mol Nutr Food Res. 2020;64:e2000196 pubmed 出版商
|
| Liu Y, Tsai J, Weng Y, Hsu F. Regorafenib suppresses epidermal growth factor receptor signaling-modulated progression of colorectal cancer. Biomed Pharmacother. 2020;128:110319 pubmed 出版商
|
| Wang Z, Yang Y, Hu S, He J, Wu Z, Qi Z, et al. Short-form RON (sf-RON) enhances glucose metabolism to promote cell proliferation via activating β-catenin/SIX1 signaling pathway in gastric cancer. Cell Biol Toxicol. 2020;: pubmed 出版商
|
| Li J, Wang L, Hua X, Tang H, Chen R, Yang T, et al. CRISPR/Cas9-Mediated miR-29b Editing as a Treatment of Different Types of Muscle Atrophy in Mice. Mol Ther. 2020;28:1359-1372 pubmed 出版商
|
| Song J, Liu L, Lv L, Hu S, Tariq A, Wang W, et al. Fluid shear stress induces Runx-2 expression via upregulation of PIEZO1 in MC3T3-E1 cells. Cell Biol Int. 2020;44:1491-1502 pubmed 出版商
|
| Tseng S, Park S, Lam B, Tsai Y, Cheng M, Farmer E, et al. Novel, genetically induced mouse model that recapitulates the histological morphology and immunosuppressive tumor microenvironment of metastatic peritoneal carcinomatosis. J Immunother Cancer. 2020;8: pubmed 出版商
|
| Gong F, Wang L, Yu L, Dang Y, Jiang X, Zhao L, et al. DHPAC, a novel microtubule depolymerizing agent, suppresses angiogenesis and vasculogenic mimicry formation of human non-small cell lung cancer. J Cell Biochem. 2020;: pubmed 出版商
|
| Tan X, Zhang K, Xu J, Qu D, Chen L, Li J, et al. Luteolin alleviates methamphetamine-induced neurotoxicity by suppressing PI3K/Akt pathway-modulated apoptosis and autophagy in rats. Food Chem Toxicol. 2020;137:111179 pubmed 出版商
|
| Huang G, Song C, Wang N, Qin T, Sui S, Obr A, et al. RNA-binding protein CUGBP1 controls the differential INSR splicing in molecular subtypes of breast cancer cells and affects cell aggressiveness. Carcinogenesis. 2020;: pubmed 出版商
|
| Gucer H, Caliskan S, Kefeli M, Mete O. Do You Know the Details of Your PAX8 Antibody? Monoclonal PAX8 (MRQ-50) Is Not Expressed in a Series of 45 Medullary Thyroid Carcinomas. Endocr Pathol. 2020;: pubmed 出版商
|
| Hou B, Li W, Li J, Ma J, Xia P, Liu Z, et al. Tumor suppressor LHPP regulates the proliferation of colorectal cancer cells via the PI3K/AKT pathway. Oncol Rep. 2020;43:536-548 pubmed 出版商
|
| Wu P, Shi X, Luo M, Inam U Llah -, Li K, Zhang M, et al. Taurine inhibits neuron apoptosis in hippocampus of diabetic rats and high glucose exposed HT-22 cells via the NGF-Akt/Bad pathway. Amino Acids. 2020;52:87-102 pubmed 出版商
|
| Xiao T, Sun J, Xing Z, Xie F, Yang L, Ding W. MTFP1 overexpression promotes the growth of oral squamous cell carcinoma by inducing ROS production. Cell Biol Int. 2020;44:821-829 pubmed 出版商
|
| Yan Z, Zang B, Gong X, Ren J, Wang R. MiR-214-3p exacerbates kidney damages and inflammation induced by hyperlipidemic pancreatitis complicated with acute renal injury. Life Sci. 2020;241:117118 pubmed 出版商
|
| Xu D, Liu J, Ma H, Guo W, Wang J, Kan X, et al. Schisandrin A protects against lipopolysaccharide-induced mastitis through activating Nrf2 signaling pathway and inducing autophagy. Int Immunopharmacol. 2020;78:105983 pubmed 出版商
|
| Liu Q, Zhang S, Zhu D, Tang X, Che Y, Feng X. The parthenolide derivative ACT001 synergizes with low doses of L-DOPA to improve MPTP-induced Parkinson's disease in mice. Behav Brain Res. 2020;379:112337 pubmed 出版商
|
| Hua W, Li S, Luo R, Wu X, Zhang Y, Liao Z, et al. Icariin protects human nucleus pulposus cells from hydrogen peroxide-induced mitochondria-mediated apoptosis by activating nuclear factor erythroid 2-related factor 2. Biochim Biophys Acta Mol Basis Dis. 2020;1866:165575 pubmed 出版商
|
| Guo S, Liu R, Wen Y, Liu L, Yuan L, Li Y, et al. Endogenous production of C-C motif chemokine ligand 2 by nasopharyngeal carcinoma cells drives radioresistance-associated metastasis. Cancer Lett. 2020;468:27-40 pubmed 出版商
|
| Wang Y, Zhao H, Guo M, Fei D, Zhang L, Xing M. Targeting the miR-122/PKM2 autophagy axis relieves arsenic stress. J Hazard Mater. 2020;383:121217 pubmed 出版商
|
| Wang J, Wan D, Wan G, Wang J, Zhang J, Zhu H. Catalpol induces cell activity to promote axonal regeneration via the PI3K/AKT/mTOR pathway in vivo and in vitro stroke model. Ann Transl Med. 2019;7:756 pubmed 出版商
|
| Zeng J, Li X, Cheng Y, Ke B, Wang R. Activation of cannabinoid receptor type 2 reduces lung ischemia reperfusion injury through PI3K/Akt pathway. Int J Clin Exp Pathol. 2019;12:4096-4105 pubmed
|
| Zhang C, Wang B, Wang X, Sheng X, Cui Y. Sevoflurane inhibits the progression of ovarian cancer through down-regulating stanniocalcin 1 (STC1). Cancer Cell Int. 2019;19:339 pubmed 出版商
|
| Liu Y, Zhang S, Xue J, Wei Z, Ao P, Shen B, et al. CGRP Reduces Apoptosis of DRG Cells Induced by High-Glucose Oxidative Stress Injury through PI3K/AKT Induction of Heme Oxygenase-1 and Nrf-2 Expression. Oxid Med Cell Longev. 2019;2019:2053149 pubmed 出版商
|
| Cai B, Lu Y, Xu M. Acid sphingomyelinase downregulation alleviates vascular endothelial leptin resistance in rats. Acta Pharmacol Sin. 2019;: pubmed 出版商
|
| Huang F, Chen J, Wang J, Zhu P, Lin W. Palmitic Acid Induces MicroRNA-221 Expression to Decrease Glucose Uptake in HepG2 Cells via the PI3K/AKT/GLUT4 Pathway. Biomed Res Int. 2019;2019:8171989 pubmed 出版商
|
| Pan C, Liu Q, Wu X. HIF1α/miR-520a-3p/AKT1/mTOR Feedback Promotes The Proliferation And Glycolysis Of Gastric Cancer Cells. Cancer Manag Res. 2019;11:10145-10156 pubmed 出版商
|
| Wang J, Li L, Wang J, Song L, Tan N, Wang Z. Natural Naphthohydroquinone Dimer Rubioncolin C Exerts Anti-Tumor Activity by Inducing Apoptotic and Autophagic Cell Death and Inhibiting the NF-κB and Akt/mTOR/P70S6K Pathway in Human Cancer Cells. Cells. 2019;8: pubmed 出版商
|
| Wang Z, Liang M, Li H, Cai L, Yang L. Rice Protein Exerts Anti-Inflammatory Effect in Growing and Adult Rats via Suppressing NF-κB Pathway. Int J Mol Sci. 2019;20: pubmed 出版商
|
| Huang H, Liu Z, Wu K, Gu S, Lu T, Zhong C, et al. MiR-92a regulates endothelial progenitor cells (EPCs) by targeting GDF11 via activate SMAD2/3/FAK/Akt/eNOS pathway. Ann Transl Med. 2019;7:563 pubmed 出版商
|
| Wang C, Le Y, Lu D, Zhao M, Dou X, Zhang Q. Triphenyl phosphate causes a sexually dimorphic metabolism dysfunction associated with disordered adiponectin receptors in pubertal mice. J Hazard Mater. 2019;:121732 pubmed 出版商
|
| Xiao Y, Wei R, Yuan Z, Lan X, Kuang J, Hu D, et al. Rutin suppresses FNDC1 expression in bone marrow mesenchymal stem cells to inhibit postmenopausal osteoporosis. Am J Transl Res. 2019;11:6680-6690 pubmed
|
| Yao X, Liu D, Zhou L, Xie Y, Li Y. FAM60A, increased by Helicobacter pylori, promotes proliferation and suppresses apoptosis of gastric cancer cells by targeting the PI3K/AKT pathway. Biochem Biophys Res Commun. 2019;: pubmed 出版商
|
| Xu W, Li J, Tian H, Wang R, Feng Y, Tang J, et al. MicroRNA‑186‑5p mediates osteoblastic differentiation and cell viability by targeting CXCL13 in non‑traumatic osteonecrosis. Mol Med Rep. 2019;20:4594-4602 pubmed 出版商
|
| Liu J, Hu Y, Feng Y, Guo Y, Liu Y, Yang J, et al. Rafoxanide promotes apoptosis and autophagy of gastric cancer cells by suppressing PI3K /Akt/mTOR pathway. Exp Cell Res. 2019;385:111691 pubmed 出版商
|
| Zhu H, Miao Y, Shen Y, Guo J, Xie W, Zhao S, et al. The clinical characteristics and molecular mechanism of pituitary adenoma associated with meningioma. J Transl Med. 2019;17:354 pubmed 出版商
|
| Wu K, Huang D, Zhu C, Kasanga E, Zhang Y, Yu E, et al. NT3P75-2 gene-modified bone mesenchymal stem cells improve neurological function recovery in mouse TBI model. Stem Cell Res Ther. 2019;10:311 pubmed 出版商
|
| Bao Y, Pang Y, Tang S, Niu T, Guo Z, He H, et al. 12N-Substituted Matrinol Derivatives Inhibited the Expression of Fibrogenic Genes via Repressing Integrin/FAK/PI3K/Akt Pathway in Hepatic Stellate Cells. Molecules. 2019;24: pubmed 出版商
|
| Li Y, Cao Y, Wang J, Fu S, Cheng J, Ma L, et al. Kp-10 promotes bovine mammary epithelial cell proliferation by activating GPR54 and its downstream signaling pathways. J Cell Physiol. 2019;: pubmed 出版商
|
| Xiong Y, Lan J, Huang K, Zhang Y, Zheng L, Wang Y, et al. PP2Ac upregulates PI3K-Akt signaling and induces hepatocyte apoptosis in liver donor after brain death. Apoptosis. 2019;24:921-933 pubmed 出版商
|
| Jing L, Jiang J, Liu D, Sheng J, Zhang W, Li Z, et al. Structural Characterization and Antioxidant Activity of Polysaccharides from Athyrium multidentatum (Doll.) Ching in d-Galactose-Induced Aging Mice via PI3K/AKT Pathway. Molecules. 2019;24: pubmed 出版商
|
| Tateyama H, Murase Y, Higuchi H, Inasaka Y, Kaneoka H, Iijima S, et al. Siglec-F is induced by granulocyte-macrophage colony-stimulating factor and enhances interleukin-4-induced expression of arginase-1 in mouse macrophages. Immunology. 2019;158:340-352 pubmed 出版商
|
| Xu Q, Long Q, Zhu D, Fu D, Zhang B, Han L, et al. Targeting amphiregulin (AREG) derived from senescent stromal cells diminishes cancer resistance and averts programmed cell death 1 ligand (PD-L1)-mediated immunosuppression. Aging Cell. 2019;18:e13027 pubmed 出版商
|
| Wen N, Guo B, Zheng H, Xu L, Liang H, Wang Q, et al. Bromodomain inhibitor jq1 induces cell cycle arrest and apoptosis of glioma stem cells through the VEGF/PI3K/AKT signaling pathway. Int J Oncol. 2019;55:879-895 pubmed 出版商
|
| He X, Jiang H, Gao F, Liang S, Wei M, Chen L. Indoxyl sulfate-induced calcification of vascular smooth muscle cells via the PI3K/Akt/NF-κB signaling pathway. Microsc Res Tech. 2019;: pubmed 出版商
|
| Lin J, Jiao A, Lv W, Zhang C, Shi Y, Yang Z, et al. Pentapeptide Protects INS-1 Cells From hIAPP-Mediated Apoptosis by Enhancing Autophagy Through mTOR Pathway. Front Pharmacol. 2019;10:896 pubmed 出版商
|
| Qiao X, Zhou Z, Niu R, Su Y, Sun Y, Liu H, et al. Hydroxychloroquine Improves Obesity-Associated Insulin Resistance and Hepatic Steatosis by Regulating Lipid Metabolism. Front Pharmacol. 2019;10:855 pubmed 出版商
|
| Guan P, Sun Z, Wang N, Zhou J, Luo L, Zhao Y, et al. Resveratrol prevents chronic intermittent hypoxia-induced cardiac hypertrophy by targeting the PI3K/AKT/mTOR pathway. Life Sci. 2019;233:116748 pubmed 出版商
|
| Li W, Jiang Y, Wang Y, Zhao M, Hou G, Hu H, et al. Protective Effects of Combination of Radix Astragali and Radix Salviae Miltiorrhizae on Kidney of Spontaneously Hypertensive Rats and Renal Intrinsic Cells. Chin J Integr Med. 2019;: pubmed 出版商
|
| Ming Yan Y, Jing Z, Shu Qin G, Xiao Liang B, Zhi Hong L, Xue Z. Liraglutide inhibits the apoptosis of human nucleus pulposus cells induced by high glucose through PI3K/Akt/caspase-3 signaling pathway. Biosci Rep. 2019;39: pubmed 出版商
|
| Xu X, Zong Y, Gao Y, Sun X, Zhao H, Luo W, et al. VEGF Induce Vasculogenic Mimicry of Choroidal Melanoma through the PI3k Signal Pathway. Biomed Res Int. 2019;2019:3909102 pubmed 出版商
|
| Dai B, Yu R, Fan M, Yang T, Wang B, Zhang Y. HMQ‑T‑F2 suppresses migration of the human cervical cancer HeLa cells by reversing EMT via the PI3K/Akt signaling pathway. Oncol Rep. 2019;: pubmed 出版商
|
| Zhao H, Wang Y, Liu J, Guo M, Fei D, Yu H, et al. The cardiotoxicity of the common carp (Cyprinus carpio) exposed to environmentally relevant concentrations of arsenic and subsequently relieved by zinc supplementation. Environ Pollut. 2019;253:741-748 pubmed 出版商
|
| Chen L, Cheng X, Tu W, Qi Z, Li H, Liu F, et al. Apatinib inhibits glycolysis by suppressing the VEGFR2/AKT1/SOX5/GLUT4 signaling pathway in ovarian cancer cells. Cell Oncol (Dordr). 2019;: pubmed 出版商
|
| Guo W, Li H, Liu H, Ma X, Yang S, Wang Z. DEPDC1 drives hepatocellular carcinoma cell proliferation, invasion and angiogenesis by regulating the CCL20/CCR6 signaling pathway. Oncol Rep. 2019;42:1075-1089 pubmed 出版商
|
| Lu Q, Liu T, Feng H, Yang R, Zhao X, Chen W, et al. Circular RNA circSLC8A1 acts as a sponge of miR-130b/miR-494 in suppressing bladder cancer progression via regulating PTEN. Mol Cancer. 2019;18:111 pubmed 出版商
|
| Wang F, Chang C, Li R, Zhang Z, Jiang H, Zeng N, et al. Retinol binding protein 4 mediates MEHP-induced glucometabolic abnormalities in HepG2 cells. Toxicology. 2019;: pubmed 出版商
|
| Lin Z, Liu Z, Wang X, Qiu C, Zheng S. MiR-21-3p Plays a Crucial Role in Metabolism Alteration of Renal Tubular Epithelial Cells during Sepsis Associated Acute Kidney Injury via AKT/CDK2-FOXO1 Pathway. Biomed Res Int. 2019;2019:2821731 pubmed 出版商
|
| Huang Q, Li S, Zhang L, Qiao X, Zhang Y, Zhao X, et al. CAPE-pNO2 Inhibited the Growth and Metastasis of Triple-Negative Breast Cancer via the EGFR/STAT3/Akt/E-Cadherin Signaling Pathway. Front Oncol. 2019;9:461 pubmed 出版商
|
| Ye Z, Zhang S, Liu Y, Wang S, Zhang J, Huang R. A Peptide Analogue of Selectin Ligands Attenuated Atherosclerosis by Inhibiting Monocyte Activation. Mediators Inflamm. 2019;2019:8709583 pubmed 出版商
|
| Diao W, Cao W, Yuan H, Ji H, Wang T, Chen W, et al. Astaxanthin protects against renal fibrosis through inhibiting myofibroblast activation and promoting CD8+ T cell recruitment. Biochim Biophys Acta Gen Subj. 2019;: pubmed 出版商
|
| Wu X, Ansari A, Pang X, Li H, Zhang Z, Luo Y, et al. Visfatin Plays a Significant Role in Alleviating Lipopolysaccharide-Induced Apoptosis and Autophagy Through PI3K/AKT Signaling Pathway During Acute Lung Injury in Mice. Arch Immunol Ther Exp (Warsz). 2019;: pubmed 出版商
|
| Yang H, Liu J, Shang H, Lin S, Zhao J, Lin J. Qingjie Fuzheng granules inhibit colorectal cancer cell growth by the PI3K/AKT and ERK pathways. World J Gastrointest Oncol. 2019;11:377-392 pubmed 出版商
|
| Wang X, Luo C, Mao X, Li X, Yin J, Zhang W, et al. Metformin reverses the schizophrenia-like behaviors induced by MK-801 in rats. Brain Res. 2019;: pubmed 出版商
|
| Xu J, Liu M, Yu M, Shen J, Zhou J, Hu J, et al. RasGRP1 is a target for VEGF to induce angiogenesis and involved in the endothelial-protective effects of metformin under high glucose in HUVECs. IUBMB Life. 2019;: pubmed 出版商
|
| Wu X, Li S, Wang K, Hua W, Li S, Song Y, et al. TNF-α Regulates ITGβ1 and SYND4 Expression in Nucleus Pulposus Cells: Activation of FAK/PI3K Signaling. Inflammation. 2019;: pubmed 出版商
|
| Qu L, Chen C, He W, Chen Y, Li Y, Wen Y, et al. Glycyrrhizic acid ameliorates LPS-induced acute lung injury by regulating autophagy through the PI3K/AKT/mTOR pathway. Am J Transl Res. 2019;11:2042-2055 pubmed
|
| Xu J, Wang Y, Xu D. Hsa_circ_001569 is an unfavorable prognostic factor and promotes cell proliferation and metastasis by modulating PI3K-AKT pathway in breast cancer. Cancer Biomark. 2019;25:193-201 pubmed 出版商
|
| Yang F, Lin Z, Huang T, Chen T, Cui J, Li M, et al. Ligustilide, a major bioactive component of Angelica sinensis, promotes bone formation via the GPR30/EGFR pathway. Sci Rep. 2019;9:6991 pubmed 出版商
|
| Sun Z, Liu Y, Yu F, Xu Y, Yanli L, Liu N. Long non-coding RNA and mRNA profile analysis of metformin to reverse the pulmonary hypertension vascular remodeling induced by monocrotaline. Biomed Pharmacother. 2019;115:108933 pubmed 出版商
|
| Yang L, Qiu T, Yao X, Jiang L, Wei S, Pei P, et al. Taurine Protects Against Arsenic Trioxide-Induced Insulin Resistance via ROS-Autophagy Pathway in Skeletal Muscle. Int J Biochem Cell Biol. 2019;: pubmed 出版商
|
| Wang C, Zheng P, Adeniran S, Ma M, Huang F, Adegoke E, et al. Thyroid hormone (T3) is involved in inhibiting the proliferation of newborn calf Sertoli cells via the PI3K/Akt signaling pathway in vitro. Theriogenology. 2019;133:1-9 pubmed 出版商
|
| Ma Q, Gao Y, Xu P, Li K, Xu X, Gao J, et al. Atorvastatin Inhibits Breast Cancer Cells by Downregulating PTEN/AKT Pathway via Promoting Ras Homolog Family Member B (RhoB). Biomed Res Int. 2019;2019:3235021 pubmed 出版商
|
| Ren D, Zhao Y, Zheng Q, Alim A, Yang X. Immunomodulatory effects of an acidic polysaccharide fraction from herbal Gynostemma pentaphyllum tea in RAW264.7 cells. Food Funct. 2019;10:2186-2197 pubmed 出版商
|
| Li Z, Chen Y, An T, Liu P, Zhu J, Yang H, et al. Nuciferine inhibits the progression of glioblastoma by suppressing the SOX2-AKT/STAT3-Slug signaling pathway. J Exp Clin Cancer Res. 2019;38:139 pubmed 出版商
|
| Gu X, Han S, Cui M, Xue J, Ai L, Sun L, et al. Knockdown of endothelin receptor B inhibits the progression of triple-negative breast cancer. Ann N Y Acad Sci. 2019;: pubmed 出版商
|
| Liu Z, Wang N, Ma Y, Wen D. Hydroxytyrosol Improves Obesity and Insulin Resistance by Modulating Gut Microbiota in High-Fat Diet-Induced Obese Mice. Front Microbiol. 2019;10:390 pubmed 出版商
|
| Dong C, Liu X, Wang H, Li J, Dai L, Li J, et al. Hypoxic non-small-cell lung cancer cell-derived exosomal miR-21 promotes resistance of normoxic cell to cisplatin. Onco Targets Ther. 2019;12:1947-1956 pubmed 出版商
|
| Chen Y, Liu P, Sun P, Jiang J, Zhu Y, Dong T, et al. Oncogenic MSH6-CXCR4-TGFB1 Feedback Loop: A Novel Therapeutic Target of Photothermal Therapy in Glioblastoma Multiforme. Theranostics. 2019;9:1453-1473 pubmed 出版商
|
| Zhu L, Wu G, Yang X, Jia X, Li J, Bai X, et al. Low density lipoprotein mimics insulin action on autophagy and glucose uptake in endothelial cells. Sci Rep. 2019;9:3020 pubmed 出版商
|
| Cao D, Qi Z, Pang Y, Li H, Xie H, Wu J, et al. Retinoic Acid-Related Orphan Receptor C Regulates Proliferation, Glycolysis, and Chemoresistance via the PD-L1/ITGB6/STAT3 Signaling Axis in Bladder Cancer. Cancer Res. 2019;79:2604-2618 pubmed 出版商
|
| Bai L, Zhang S, Zhou X, Li Y, Bai J. Brain-derived neurotrophic factor induces thioredoxin-1 expression through TrkB/Akt/CREB pathway in SH-SY5Y cells. Biochimie. 2019;160:55-60 pubmed 出版商
|
| Bei Y, Pan L, Zhou Q, Zhao C, Xie Y, Wu C, et al. Cathelicidin-related antimicrobial peptide protects against myocardial ischemia/reperfusion injury. BMC Med. 2019;17:42 pubmed 出版商
|
| Mao Z, Han X, Chen D, Xu Y, Xu L, Yin L, et al. Potent effects of dioscin against hepatocellular carcinoma through regulating TP53-induced glycolysis and apoptosis regulator (TIGAR)-mediated apoptosis, autophagy, and DNA damage. Br J Pharmacol. 2019;176:919-937 pubmed 出版商
|
| Zhou T, Sun Y, Wang Y, Chen X, Zhuo L, Bu L, et al. Umbilical Cord Blood Mesenchymal Stem Cells Enhance Lipopolysaccharide-Induced IL-10 and IL-37 Production in THP-1 Cells. Inflammation. 2019;42:987-993 pubmed 出版商
|
| Pan Q, Wu J, Liu Y, Li X, Chen J. Involvement of Hepatic SHIP2 and PI3K/Akt Signalling in the Regulation of Plasma Insulin by Xiaoyaosan in Chronic Immobilization-Stressed Rats. Molecules. 2019;24: pubmed 出版商
|
| Zhang Y, Li Q, Yu S, Zhu C, Zhang Z, Cao H, et al. Long non-coding RNA FAM84B-AS promotes resistance of gastric cancer to platinum drugs through inhibition of FAM84B expression. Biochem Biophys Res Commun. 2019;: pubmed 出版商
|
| Liang H, Mokrani A, Chisomo Kasiya H, Ji K, Ge X, Ren M, et al. Dietary leucine affects glucose metabolism and lipogenesis involved in TOR/PI3K/Akt signaling pathway for juvenile blunt snout bream Megalobrama amblycephala. Fish Physiol Biochem. 2019;45:719-732 pubmed 出版商
|
| Cui K, Luan Y, Tang Z, Li C, Wang T, Wang S, et al. Human tissue kallikrein-1 protects against the development of erectile dysfunction in a rat model of hyperhomocysteinemia. Asian J Androl. 2019;: pubmed 出版商
|
| Zhu B, Long Y, Luo W, Yan Z, Lai Y, Zhao L, et al. MMP13 inhibition rescues cognitive decline in Alzheimer transgenic mice via BACE1 regulation. Brain. 2019;142:176-192 pubmed 出版商
|
| Zhang D, Zhang J, Zeng J, Li Z, Zuo H, Huang C, et al. Nano-Gold Loaded with Resveratrol Enhance the Anti-Hepatoma Effect of Resveratrol In Vitro and In Vivo. J Biomed Nanotechnol. 2019;15:288-300 pubmed 出版商
|
| Zhang X, Liu J, Gu Y, Sun C, Qu F. Down-regulation of lncRNA OGFRP1 induces autophagy and growth inhibition by AKT/mTOR signaling pathway in HCAECs. Cell Biol Int. 2019;43:158-166 pubmed 出版商
|
| Wan G, Cheng L, Qin H, Zhang Y, Wang L, Zhang Y. MiR-15b-5p is Involved in Doxorubicin-Induced Cardiotoxicity via Inhibiting Bmpr1a Signal in H9c2 Cardiomyocyte. Cardiovasc Toxicol. 2019;19:264-275 pubmed 出版商
|
| Wang Y, Piao J, Wang Q, Cui X, Meng Z, Jin T, et al. Paip1 predicts poor prognosis and promotes tumor progression through AKT/GSK-3β pathway in lung adenocarcinoma. Hum Pathol. 2019;86:233-242 pubmed 出版商
|
| Gao N, Yao X, Jiang L, Yang L, Qiu T, Wang Z, et al. Taurine improves low-level inorganic arsenic-induced insulin resistance by activating PPARγ-mTORC2 signalling and inhibiting hepatic autophagy. J Cell Physiol. 2019;234:5143-5152 pubmed 出版商
|
| Cui K, Li R, Liu K, Wang T, Liu J, Rao K. Testosterone preserves endothelial function through regulation of S1P1/Akt/FOXO3a signalling pathway in the rat corpus cavernosum. Andrologia. 2019;51:e13173 pubmed 出版商
|
| Li S, Wang Y, Zhao H, Shao Y, Liu J, Xing M. Characterization, functional and signaling elucidation of pigeon (Columba livia) interferon-α: Knockdown p53 negatively modulates antiviral response. Dev Comp Immunol. 2019;90:29-40 pubmed 出版商
|
| Zhao G, Li K, Chen J, Li L. Protective Effect of Extract of Bletilla Striata on Isoflurane Induced Neuronal Injury By Altering PI3K/Akt Pathway. Transl Neurosci. 2018;9:183-189 pubmed 出版商
|
| Dong H, Cao W, Xue J. Long noncoding FOXD2-AS1 is activated by CREB1 and promotes cell proliferation and metastasis in glioma by sponging miR-185 through targeting AKT1. Biochem Biophys Res Commun. 2018;: pubmed 出版商
|
| Huang C, Ji X, Peng Y, Wu M, Wu W, Luo Y, et al. Silencing of rhomboid domain containing 1 to inhibit the metastasis of human breast cancer cells in vitro. Iran J Basic Med Sci. 2018;21:1161-1166 pubmed 出版商
|
| Jiang T, Zhou M, Fan J. Inhibition of GLUT-1 expression and the PI3K/Akt pathway to enhance the chemosensitivity of laryngeal carcinoma cells in vitro. Onco Targets Ther. 2018;11:7865-7872 pubmed 出版商
|
| Wang J, Yang C, Yuan Z, Yi J, Wu J. T-2 Toxin Exposure Induces Apoptosis in TM3 Cells by Inhibiting Mammalian Target of Rapamycin/Serine/Threonine Protein Kinase(mTORC2/AKT) to Promote Ca2+Production. Int J Mol Sci. 2018;19: pubmed 出版商
|
| Liu Y, Gao Y, Li D, He L, Iw L, Hao B, et al. LASP1 promotes glioma cell proliferation and migration and is negatively regulated by miR-377-3p. Biomed Pharmacother. 2018;108:845-851 pubmed 出版商
|
| Yang Y, Sun Y, Xu J, Bao K, Luo M, Liu X, et al. Epithelial Cells Attenuate Toll-Like Receptor-Mediated Inflammatory Responses in Monocyte-Derived Macrophage-Like Cells to Mycobacterium tuberculosis by Modulating the PI3K/Akt/mTOR Signaling Pathway. Mediators Inflamm. 2018;2018:3685948 pubmed 出版商
|
| Song J, Qiu W, Deng X, Qiu Z, Fan Y, Yang Z. A somatic mutation of RasGRP3 decreases Na+/I- symporter expression in metastases of radioactive iodine-refractory thyroid cancer by stimulating the Akt signaling pathway. Am J Cancer Res. 2018;8:1847-1855 pubmed
|
| Deng G, Li K, Chen S, Chen P, Zheng H, Yu B, et al. Interleukin‑10 promotes proliferation and migration, and inhibits tendon differentiation via the JAK/Stat3 pathway in tendon‑derived stem cells in vitro. Mol Med Rep. 2018;18:5044-5052 pubmed 出版商
|
| Liu L, Wang N, Ma Y, Liu Y, Wen D. Saponins from Boussingaultia gracilis prevent obesity and related metabolic impairments in diet-induced obese mice. Food Funct. 2018;9:5660-5673 pubmed 出版商
|
| Batool S, Joseph T, Hussain M, Vuai M, Khinsar K, Din S, et al. LP1 from Lentinula edodes C91-3 Induces Autophagy, Apoptosis and Reduces Metastasis in Human Gastric Cancer Cell Line SGC-7901. Int J Mol Sci. 2018;19: pubmed 出版商
|
| Mu Z, Sun Q. Cantharidin inhibits melanoma cell proliferation via the miR‑21‑mediated PTEN pathway. Mol Med Rep. 2018;18:4603-4610 pubmed 出版商
|
| Tan F, Huang Y, Pei Q, Liu H, Pei H, Zhu H. Matrix stiffness mediates stemness characteristics via activating the Yes-associated protein in colorectal cancer cells. J Cell Biochem. 2018;: pubmed 出版商
|
| Sun D, Zhang F, Qian J, Shen W, Fan H, Tan J, et al. 4'-hydroxywogonin inhibits colorectal cancer angiogenesis by disrupting PI3K/AKT signaling. Chem Biol Interact. 2018;296:26-33 pubmed 出版商
|
| Nie X, Fan J, Li H, Yin Z, Zhao Y, Dai B, et al. miR-217 Promotes Cardiac Hypertrophy and Dysfunction by Targeting PTEN. Mol Ther Nucleic Acids. 2018;12:254-266 pubmed 出版商
|
| Zou W, Ding F, Niu C, Fu Z, Liu S. Brg1 aggravates airway inflammation in asthma via inhibition of the PI3K/Akt/mTOR pathway. Biochem Biophys Res Commun. 2018;503:3212-3218 pubmed 出版商
|
| Xue Y, Jia X, Li L, Dong X, Ling J, Yuan J, et al. DDX5 promotes hepatocellular carcinoma tumorigenesis via Akt signaling pathway. Biochem Biophys Res Commun. 2018;503:2885-2891 pubmed 出版商
|
| Wang Y, Wang Y, Liu Z, Dong W, Yang B, Xia X, et al. Polychlorinated Biphenyl Quinones Promotes Breast Cancer Metastasis through Reactive Oxygen Species-Mediated Nuclear Factor κB-Matrix Metalloproteinase Signaling. Chem Res Toxicol. 2018;31:954-963 pubmed 出版商
|
| Zhou W, Wang J, Qi Q, Feng Z, Huang B, Chen A, et al. Matrine induces senescence of human glioblastoma cells through suppression of the IGF1/PI3K/AKT/p27 signaling pathway. Cancer Med. 2018;7:4729-4743 pubmed 出版商
|
| Song Y, Gao L, Tang Z, Li H, Sun B, Chu P, et al. Anticancer effect of SZC015 on pancreatic cancer via mitochondria-dependent apoptosis and the constitutive suppression of activated nuclear factor κB and STAT3 in vitro and in vivo. J Cell Physiol. 2018;234:777-788 pubmed 出版商
|
| Kong F, Ma J, Yang H, Yang D, Wang C, Ma X. Long non-coding RNA PVT1 promotes malignancy in human endometrial carcinoma cells through negative regulation of miR-195-5p. Biochim Biophys Acta Mol Cell Res. 2018;: pubmed 出版商
|
| Zhu X, Wang J, Li L, Deng L, Wang J, Liu L, et al. GPX3 suppresses tumor migration and invasion via the FAK/AKT pathway in esophageal squamous cell carcinoma. Am J Transl Res. 2018;10:1908-1920 pubmed
|
| Yang T, Ren C, Qiao P, Han X, Wang L, Lv S, et al. PIM2-mediated phosphorylation of hexokinase 2 is critical for tumor growth and paclitaxel resistance in breast cancer. Oncogene. 2018;37:5997-6009 pubmed 出版商
|
| Lin X, Cui H, Yang A, Luo J, Tang T. Astragaloside IV Improves Vasodilatation Function by Regulating the PI3K/Akt/eNOS Signaling Pathway in Rat Aorta Endothelial Cells. J Vasc Res. 2018;55:169-176 pubmed 出版商
|
| Li Y, Zeng C, Hu J, Pan Y, Shan Y, Liu B, et al. Long non-coding RNA-SNHG7 acts as a target of miR-34a to increase GALNT7 level and regulate PI3K/Akt/mTOR pathway in colorectal cancer progression. J Hematol Oncol. 2018;11:89 pubmed 出版商
|
| Xu N, Fan W, Zhou X, Liu Y, Ma P, Qi S, et al. Probiotics decrease depressive behaviors induced by constipation via activating the AKT signaling pathway. Metab Brain Dis. 2018;33:1625-1633 pubmed 出版商
|
| Liu C, Zhang Y, She X, Fan L, Li P, Feng J, et al. A cytoplasmic long noncoding RNA LINC00470 as a new AKT activator to mediate glioblastoma cell autophagy. J Hematol Oncol. 2018;11:77 pubmed 出版商
|
| Liu F, Wen Y, Kang J, Wei C, Wang M, Zheng Z, et al. Regulation of TLR4 expression mediates the attenuating effect of erythropoietin on inflammation and myocardial fibrosis in rat heart. Int J Mol Med. 2018;42:1436-1444 pubmed 出版商
|
| Ke M, Dong J, Wang Y, Zhang J, Zhang M, Wu Z, et al. MEL-pep, an analog of melittin, disrupts cell membranes and reverses 5-fluorouracil resistance in human hepatocellular carcinoma cells. Int J Biochem Cell Biol. 2018;101:39-48 pubmed 出版商
|
| Wang N, Liu Y, Ma Y, Wen D. Hydroxytyrosol ameliorates insulin resistance by modulating endoplasmic reticulum stress and prevents hepatic steatosis in diet-induced obesity mice. J Nutr Biochem. 2018;57:180-188 pubmed 出版商
|
| Li P, Guo H, Zhou G, Shi H, Li Z, Guan X, et al. Increased ZNF84 expression in cervical cancer. Arch Gynecol Obstet. 2018;297:1525-1532 pubmed 出版商
|
| Yang G, Bai Y, Wu X, Sun X, Sun M, Liu X, et al. Patulin induced ROS-dependent autophagic cell death in Human Hepatoma G2 cells. Chem Biol Interact. 2018;288:24-31 pubmed 出版商
|
| Cao R, Jin W, Shan Y, Wang J, Liu G, Kuang S, et al. Marine Bacterial Polysaccharide EPS11 Inhibits Cancer Cell Growth via Blocking Cell Adhesion and Stimulating Anoikis. Mar Drugs. 2018;16: pubmed 出版商
|
| Chen X, Tian M, Sun R, Zhang M, Zhou L, Jin L, et al. SIRT5 inhibits peroxisomal ACOX1 to prevent oxidative damage and is downregulated in liver cancer. EMBO Rep. 2018;19: pubmed 出版商
|
| Yin N, Wang Y, Lu X, Liu R, Zhang L, Zhao W, et al. hPMSC transplantation restoring ovarian function in premature ovarian failure mice is associated with change of Th17/Tc17 and Th17/Treg cell ratios through the PI3K/Akt signal pathway. Stem Cell Res Ther. 2018;9:37 pubmed 出版商
|
| Jia Y, Lu H, Peng Y, Zhang B, Gong X, Su J, et al. Oxyresveratrol prevents lipopolysaccharide/d-galactosamine-induced acute liver injury in mice. Int Immunopharmacol. 2018;56:105-112 pubmed 出版商
|
| Shi X, Ran L, Liu Y, Zhong S, Zhou P, Liao M, et al. Knockdown of hnRNP A2/B1 inhibits cell proliferation, invasion and cell cycle triggering apoptosis in cervical cancer via PI3K/AKT signaling pathway. Oncol Rep. 2018;39:939-950 pubmed 出版商
|
| Li H, Fu X, Gao Y, Li X, Shen Y, Wang W. Small interfering RNA-mediated silencing of G-protein-coupled receptor 137 inhibits growth of osteosarcoma cells. J Bone Oncol. 2018;11:17-22 pubmed 出版商
|
| Wei W, An X, Jin S, Li X, Xu M. Inhibition of insulin resistance by PGE1 via autophagy-dependent FGF21 pathway in diabetic nephropathy. Sci Rep. 2018;8:9 pubmed 出版商
|
| Gao Y, Yu H, Liu Y, Liu X, Zheng J, Ma J, et al. Long Non-Coding RNA HOXA-AS2 Regulates Malignant Glioma Behaviors and Vasculogenic Mimicry Formation via the MiR-373/EGFR Axis. Cell Physiol Biochem. 2018;45:131-147 pubmed 出版商
|
| Yan J, Wang C, Jin Y, Meng Q, Liu Q, Liu Z, et al. Catalpol ameliorates hepatic insulin resistance in type 2 diabetes through acting on AMPK/NOX4/PI3K/AKT pathway. Pharmacol Res. 2018;130:466-480 pubmed 出版商
|
| Wu X, Song Y, Li S, Liu X, Hua W, Wang K, et al. Pramlintide regulation of extracellular matrix (ECM) and apoptosis through mitochondrial-dependent pathways in human nucleus pulposus cells. Int J Immunopathol Pharmacol. 2018;31:394632017747500 pubmed 出版商
|
| Huang L, Chen C, Zhang X, Li X, Chen Z, Yang C, et al. Neuroprotective Effect of Curcumin Against Cerebral Ischemia-Reperfusion Via Mediating Autophagy and Inflammation. J Mol Neurosci. 2018;64:129-139 pubmed 出版商
|
| Duan J, Du C, Shi Y, Liu D, Ma J. Thioredoxin-interacting protein deficiency ameliorates diabetic retinal angiogenesis. Int J Biochem Cell Biol. 2018;94:61-70 pubmed 出版商
|
| Liu C, Xing J, Gao Y. UNBS5162 inhibits the proliferation of human A549 non-small-cell lung cancer cells by promoting apoptosis. Thorac Cancer. 2018;9:105-111 pubmed 出版商
|
| He D, Zhang S. UNBS5162 inhibits the proliferation of esophageal cancer squamous cells via the PI3K/AKT signaling pathway. Mol Med Rep. 2018;17:549-555 pubmed 出版商
|
| Sun X, Li J, Zhao H, Wang Y, Liu J, Shao Y, et al. Synergistic effect of copper and arsenic upon oxidative stress, inflammation and autophagy alterations in brain tissues of Gallus gallus. J Inorg Biochem. 2018;178:54-62 pubmed 出版商
|
| Zhang W, Zhu Y, Yang G, Liu X, Xia B, Hu X, et al. Lactobacillus rhamnosus GG Affects Microbiota and Suppresses Autophagy in the Intestines of Pigs Challenged with Salmonella Infantis. Front Microbiol. 2017;8:2705 pubmed 出版商
|
| Wang X, Li D, Fan L, Xiao Q, Zuo H, Li Z. CAPE-pNO2 ameliorated diabetic nephropathy through regulating the Akt/NF-?B/ iNOS pathway in STZ-induced diabetic mice. Oncotarget. 2017;8:114506-114525 pubmed 出版商
|
| Yan Z, Feng J, Peng J, Lai Z, Zhang L, Jin Y, et al. Chloroform extract of Hedyotis diffusa Willd inhibits viability of human colorectal cancer cells via suppression of AKT and ERK signaling pathways. Oncol Lett. 2017;14:7923-7930 pubmed 出版商
|
| Jin Y, Chen W, Yang H, Yan Z, Lai Z, Feng J, et al. Scutellaria barbata D. Don inhibits migration and invasion of colorectal cancer cells via suppression of PI3K/AKT and TGF-?/Smad signaling pathways. Exp Ther Med. 2017;14:5527-5534 pubmed 出版商
|
| Zhang J, Zhao J, Zheng X, Cai K, Mao Q, Xia H. Establishment of a novel hepatic steatosis cell model by Cas9/sgRNA-mediated DGK? gene knockout. Mol Med Rep. 2017;: pubmed 出版商
|
| Zhao J, Zhu J, Lv X, Xing J, Liu S, Chen C, et al. Curcumin potentiates the potent antitumor activity of ACNU against glioblastoma by suppressing the PI3K/AKT and NF-?B/COX-2 signaling pathways. Onco Targets Ther. 2017;10:5471-5482 pubmed 出版商
|
| Song L, Wang Z, Wang Y, Guo D, Yang J, Chen L, et al. Natural Cyclopeptide RA-XII, a New Autophagy Inhibitor, Suppresses Protective Autophagy for Enhancing Apoptosis through AMPK/mTOR/P70S6K Pathways in HepG2 Cells. Molecules. 2017;22: pubmed 出版商
|
| Sheng C, Xu P, Zhou K, Deng D, Zhang C, Wang Z. Icariin Attenuates Synaptic and Cognitive Deficits in an A?1-42-Induced Rat Model of Alzheimer's Disease. Biomed Res Int. 2017;2017:7464872 pubmed 出版商
|
| Liu J, Wang L, Du Y, Liu S. An Important Function of Petrosiol E in Inducing the Differentiation of Neuronal Progenitors and in Protecting Them against Oxidative Stress. Adv Sci (Weinh). 2017;4:1700089 pubmed 出版商
|
| Jia L, Luo S, Ren X, Li Y, Hu J, Liu B, et al. miR-182 and miR-135b Mediate the Tumorigenesis and Invasiveness of Colorectal Cancer Cells via Targeting ST6GALNAC2 and PI3K/AKT Pathway. Dig Dis Sci. 2017;62:3447-3459 pubmed 出版商
|
| Li F, Li Q, Shi X, Guo Y. Maslinic acid inhibits impairment of endothelial functions induced by high glucose in HAEC cells through improving insulin signaling and oxidative stress. Biomed Pharmacother. 2017;95:904-913 pubmed 出版商
|
| Song Y, Kong L, Sun B, Gao L, Chu P, Ahsan A, et al. Induction of autophagy by an oleanolic acid derivative, SZC017, promotes ROS-dependent apoptosis through Akt and JAK2/STAT3 signaling pathway in human lung cancer cells. Cell Biol Int. 2017;41:1367-1378 pubmed 出版商
|
| Qiu W, Xia X, Qiu Z, Guo M, Yang Z. RasGRP3 controls cell proliferation and migration in papillary thyroid cancer by regulating the Akt-MDM2 pathway. Gene. 2017;633:35-41 pubmed 出版商
|
| Liang J, Gao W, Cai L. Fucosyltransferase VII promotes proliferation via the EGFR/AKT/mTOR pathway in A549 cells. Onco Targets Ther. 2017;10:3971-3978 pubmed 出版商
|
| Wang H, Cai J, Du S, Guo Z, Xin B, Wang J, et al. Fractalkine/CX3CR1 induces apoptosis resistance and proliferation through the activation of the AKT/NF-?B cascade in pancreatic cancer cells. Cell Biochem Funct. 2017;35:315-326 pubmed 出版商
|
| Wang N, Liu Y, Ma Y, Wen D. High-intensity interval versus moderate-intensity continuous training: Superior metabolic benefits in diet-induced obesity mice. Life Sci. 2017;191:122-131 pubmed 出版商
|
| Wu L, Zhang Q, Mo W, Feng J, Li S, Li J, et al. Quercetin prevents hepatic fibrosis by inhibiting hepatic stellate cell activation and reducing autophagy via the TGF-β1/Smads and PI3K/Akt pathways. Sci Rep. 2017;7:9289 pubmed 出版商
|
| Zhuang S, Jian Y, Sun Y. Inhibition of N-methyl-N-nitrosourea-induced gastric tumorigenesis by Liuwei Dihuang Pill in db/db mice. World J Gastroenterol. 2017;23:4233-4242 pubmed 出版商
|
| Du C, Zhang T, Xiao X, Shi Y, Duan H, Ren Y. Protease-activated receptor-2 promotes kidney tubular epithelial inflammation by inhibiting autophagy via the PI3K/Akt/mTOR signalling pathway. Biochem J. 2017;474:2733-2747 pubmed 出版商
|
| Xu L, Yin L, Tao X, Qi Y, Han X, Xu Y, et al. Dioscin, a potent ITGA5 inhibitor, reduces the synthesis of collagen against liver fibrosis: Insights from SILAC-based proteomics analysis. Food Chem Toxicol. 2017;107:318-328 pubmed 出版商
|
| Liu N, Jiang L, Sun X, Yao X, Zhai X, Liu X, et al. Mono-(2-ethylhexyl) phthalate induced ROS-dependent autophagic cell death in human vascular endothelial cells. Toxicol In Vitro. 2017;44:49-56 pubmed 出版商
|
| Lu S, Wang C, Jin Y, Meng Q, Liu Q, Liu Z, et al. The osteogenesis-promoting effects of alpha-lipoic acid against glucocorticoid-induced osteoporosis through the NOX4, NF-kappaB, JNK and PI3K/AKT pathways. Sci Rep. 2017;7:3331 pubmed 出版商
|
| Ke Z, Wang G, Yang L, Qiu H, Wu H, Du M, et al. Crude terpene glycoside component from Radix paeoniae rubra protects against isoproterenol-induced myocardial ischemic injury via activation of the PI3K/AKT/mTOR signaling pathway. J Ethnopharmacol. 2017;206:160-169 pubmed 出版商
|
| Song Z, Yang W, Zhou X, Yang L, Zhao D. Lithium alleviates neurotoxic prion peptide-induced synaptic damage and neuronal death partially by the upregulation of nuclear target REST and the restoration of Wnt signaling. Neuropharmacology. 2017;123:332-348 pubmed 出版商
|
| Li J, Chan M, Yu Y, Bei Y, Chen P, Zhou Q, et al. miR-29b contributes to multiple types of muscle atrophy. Nat Commun. 2017;8:15201 pubmed 出版商
|
| Song Z, Shah S, Yang W, Dong H, Yang L, Zhou X, et al. Downregulation of the Repressor Element 1-Silencing Transcription Factor (REST) Is Associated with Akt-mTOR and Wnt-?-Catenin Signaling in Prion Diseases Models. Front Mol Neurosci. 2017;10:128 pubmed 出版商
|
| Wu X, Wang K, Hua W, Li S, Liu X, Liu W, et al. Down-regulation of islet amyloid polypeptide expression induces death of human annulus fibrosus cells via mitochondrial and death receptor pathways. Biochim Biophys Acta Mol Basis Dis. 2017;1863:1479-1491 pubmed 出版商
|
| Xu J, Zhang S, Wang R, Wu X, Zeng L, Fu Z. Knockdown of PRDX2 sensitizes colon cancer cells to 5-FU by suppressing the PI3K/AKT signaling pathway. Biosci Rep. 2017;37: pubmed 出版商
|
| Xie X, Zhao N, Xu Q, Yang X, Xia W, Chen Q, et al. Relaxin attenuates aristolochic acid induced human tubular epithelial cell apoptosis in vitro by activation of the PI3K/Akt signaling pathway. Apoptosis. 2017;22:769-776 pubmed 出版商
|
| Yao H, Sun Y, Song S, Qi Y, Tao X, Xu L, et al. Protective Effects of Dioscin against Lipopolysaccharide-Induced Acute Lung Injury through Inhibition of Oxidative Stress and Inflammation. Front Pharmacol. 2017;8:120 pubmed 出版商
|
| Liu W, Zhang B, Hu Q, Qin Y, Xu W, Shi S, et al. A new facet of NDRG1 in pancreatic ductal adenocarcinoma: Suppression of glycolytic metabolism. Int J Oncol. 2017;50:1792-1800 pubmed 出版商
|
| Zhou W, Liu L, Xue Y, Zheng J, Liu X, Ma J, et al. Combination of Endothelial-Monocyte-Activating Polypeptide-II with Temozolomide Suppress Malignant Biological Behaviors of Human Glioblastoma Stem Cells via miR-590-3p/MACC1 Inhibiting PI3K/AKT/mTOR Signal Pathway. Front Mol Neurosci. 2017;10:68 pubmed 出版商
|
| He W, Wang C, Mu R, Liang P, Huang Z, Zhang J, et al. MiR-21 is required for anti-tumor immune response in mice: an implication for its bi-directional roles. Oncogene. 2017;36:4212-4223 pubmed 出版商
|
| Liu S, Sun Z, Chu P, Li H, Ahsan A, Zhou Z, et al. EGCG protects against homocysteine-induced human umbilical vein endothelial cells apoptosis by modulating mitochondrial-dependent apoptotic signaling and PI3K/Akt/eNOS signaling pathways. Apoptosis. 2017;22:672-680 pubmed 出版商
|
| Lu J, Xie L, Liu C, Zhang Q, Sun S. PTEN/PI3k/AKT Regulates Macrophage Polarization in Emphysematous mice. Scand J Immunol. 2017;85:395-405 pubmed 出版商
|
| Ren D, Lin D, Alim A, Zheng Q, Yang X. Chemical characterization of a novel polysaccharide ASKP-1 from Artemisia sphaerocephala Krasch seed and its macrophage activation via MAPK, PI3k/Akt and NF-?B signaling pathways in RAW264.7 cells. Food Funct. 2017;8:1299-1312 pubmed 出版商
|
| Xu G, Guo Y, Xu D, Wang Y, Shen Y, Wang F, et al. TRIM14 regulates cell proliferation and invasion in osteosarcoma via promotion of the AKT signaling pathway. Sci Rep. 2017;7:42411 pubmed 出版商
|
| Ren K, Lu Y, Mo Z, Liu X, Tang Z, Jiang Y, et al. ApoA-I/SR-BI modulates S1P/S1PR2-mediated inflammation through the PI3K/Akt signaling pathway in HUVECs. J Physiol Biochem. 2017;73:287-296 pubmed 出版商
|
| Yin K, Zhu R, Wang S, Zhao R. Low-Level Laser Effect on Proliferation, Migration, and Antiapoptosis of Mesenchymal Stem Cells. Stem Cells Dev. 2017;26:762-775 pubmed 出版商
|
| Huang T, Xiao Y, Yi L, Li L, Wang M, Tian C, et al. Coptisine from Rhizoma Coptidis Suppresses HCT-116 Cells-related Tumor Growth in vitro and in vivo. Sci Rep. 2017;7:38524 pubmed 出版商
|
| Cui K, Ruan Y, Wang T, Rao K, Chen Z, Wang S, et al. FTY720 Supplementation Partially Improves Erectile Dysfunction in Rats With Streptozotocin-Induced Type 1 Diabetes Through Inhibition of Endothelial Dysfunction and Corporal Fibrosis. J Sex Med. 2017;14:323-335 pubmed 出版商
|
| Zhang C, Li C, Chen S, Li Z, Ma L, Jia X, et al. Hormetic effect of panaxatriol saponins confers neuroprotection in PC12 cells and zebrafish through PI3K/AKT/mTOR and AMPK/SIRT1/FOXO3 pathways. Sci Rep. 2017;7:41082 pubmed 出版商
|
| Li R, Yuan F, Fu W, Zhang L, Zhang N, Wang Y, et al. Serine/Threonine Kinase Unc-51-like Kinase-1 (Ulk1) Phosphorylates the Co-chaperone Cell Division Cycle Protein 37 (Cdc37) and Thereby Disrupts the Stability of Cdc37 Client Proteins. J Biol Chem. 2017;292:2830-2841 pubmed 出版商
|
| Xue C, Wang C, Sun Y, Meng Q, Liu Z, Huo X, et al. Targeting P-glycoprotein function, p53 and energy metabolism: Combination of metformin and 2-deoxyglucose reverses the multidrug resistance of MCF-7/Dox cells to doxorubicin. Oncotarget. 2017;8:8622-8632 pubmed 出版商
|
| Wang T, Yang S, Liu S, Wang H, Liu H, Ding W. 17?-Estradiol Inhibites Tumor Necrosis Factor-? Induced Apoptosis of Human Nucleus Pulposus Cells via the PI3K/Akt Pathway. Med Sci Monit. 2016;22:4312-4322 pubmed
|
| Liu N, Li J, Zhao Z, Han J, Jiang T, Chen Y, et al. MicroRNA-302a enhances 5-fluorouracil-induced cell death in human colon cancer cells. Oncol Rep. 2017;37:631-639 pubmed 出版商
|
| Wang X, Yuan W, Wang X, Qi J, Qin Y, Shi Y, et al. The somite-secreted factor Maeg promotes zebrafish embryonic angiogenesis. Oncotarget. 2016;7:77749-77763 pubmed 出版商
|
| Sun B, Gao L, Ahsan A, Chu P, Song Y, Li H, et al. Anticancer effect of SZC015 on lung cancer cells through ROS-dependent apoptosis and autophagy induction mechanisms in vitro. Int Immunopharmacol. 2016;40:400-409 pubmed 出版商
|
| Sun B, Bai Y, Zhang L, Gong L, Qi X, Li H, et al. Quantitative Proteomic Profiling the Molecular Signatures of Annexin A5 in Lung Squamous Carcinoma Cells. PLoS ONE. 2016;11:e0163622 pubmed 出版商
|
| Chu P, Han G, Ahsan A, Sun Z, Liu S, Zhang Z, et al. Phosphocreatine protects endothelial cells from Methylglyoxal induced oxidative stress and apoptosis via the regulation of PI3K/Akt/eNOS and NF-?B pathway. Vascul Pharmacol. 2017;91:26-35 pubmed 出版商
|
| Song Y, Sun B, Hao L, Hu J, Du S, Zhou X, et al. Elevated eukaryotic elongation factor 2 expression is involved in proliferation and invasion of lung squamous cell carcinoma. Oncotarget. 2016;7:58470-58482 pubmed 出版商
|
| Cao N, Ma X, Guo Z, Zheng Y, Geng S, Meng M, et al. Oral kanglaite injection (KLTI) attenuates the lung cancer-promoting effect of high-fat diet (HFD)-induced obesity. Oncotarget. 2016;7:61093-61106 pubmed 出版商
|
| Du C, Wu M, Liu H, Ren Y, Du Y, Wu H, et al. Thioredoxin-interacting protein regulates lipid metabolism via Akt/mTOR pathway in diabetic kidney disease. Int J Biochem Cell Biol. 2016;79:1-13 pubmed 出版商
|
| Wei W, Shen C, Song H, Qiu Z, Luo Q. Propranolol sensitizes thyroid cancer cells to cytotoxic effect of vemurafenib. Oncol Rep. 2016;36:1576-84 pubmed 出版商
|
| Niu X, Fu N, Du J, Wang R, Wang Y, Zhao S, et al. miR-1273g-3p modulates activation and apoptosis of hepatic stellate cells by directly targeting PTEN in HCV-related liver fibrosis. FEBS Lett. 2016;590:2709-24 pubmed 出版商
|
| Huang C, Lei K, Tsang N. Paper-based microreactor array for rapid screening of cell signaling cascades. Lab Chip. 2016;16:2911-20 pubmed 出版商
|
| Zhang L, Liu L, He X, Shen Y, Liu X, Wei J, et al. CHIP promotes thyroid cancer proliferation via activation of the MAPK and AKT pathways. Biochem Biophys Res Commun. 2016;477:356-62 pubmed 出版商
|
| Liu H, Tao Y, Luo P, Deng C, Gu Y, Yang L, et al. Preventive Effects of a Novel Polysaccharide from Sepia esculenta Ink on Ovarian Failure and Its Action Mechanisms in Cyclophosphamide-Treated Mice. J Agric Food Chem. 2016;64:5759-66 pubmed 出版商
|
| Zhao S, Cao Y, Liu S, Wang X, Bao R, Shu Y, et al. The E545K mutation of PIK3CA promotes gallbladder carcinoma progression through enhanced binding to EGFR. J Exp Clin Cancer Res. 2016;35:97 pubmed 出版商
|
| Ren S, Zhou Y, Fang X, She X, Wu Y, Wu X. PRL-3 Is Involved in Estrogen- and IL-6-Induced Migration of Endometrial Stromal Cells From Ectopic Endometrium. Reprod Sci. 2017;24:124-132 pubmed 出版商
|
| Wang W, McKinnie S, Farhan M, Paul M, McDonald T, McLean B, et al. Angiotensin-Converting Enzyme 2 Metabolizes and Partially Inactivates Pyr-Apelin-13 and Apelin-17: Physiological Effects in the Cardiovascular System. Hypertension. 2016;68:365-77 pubmed 出版商
|
| Zhang S, Zhang C, Tang S, Deng S, Zhou Y, Dai C, et al. AKT/TSC2/p70S6K signaling pathway is involved in quinocetone-induced death-promoting autophagy in HepG2 cells. Toxicol Mech Methods. 2016;26:301-10 pubmed 出版商
|
| Du Q, Hao C, Gou J, Li X, Zou K, He X, et al. Protective effects of p-nitro caffeic acid phenethyl ester on acute myocardial ischemia-reperfusion injury in rats. Exp Ther Med. 2016;11:1433-1440 pubmed
|
| Chen G, Le Y, Zhou L, Gong L, Li X, Li Y, et al. Dexmedetomidine Inhibits Maturation and Function of Human Cord Blood-Derived Dendritic Cells by Interfering with Synthesis and Secretion of IL-12 and IL-23. PLoS ONE. 2016;11:e0153288 pubmed 出版商
|
| Olds W, Li J. siRNA knockdown validation 101: Incorporating negative controls in antibody research. F1000Res. 2016;5:308 pubmed 出版商
|
| Lu Y, Wang Y, Zhang M, Liu L, Li F, Zhang J, et al. HER2-siRNA delivered by EGFR-specific single chain antibody inhibits NSCLC cell proliferation and tumor growth. Oncotarget. 2016;7:23594-607 pubmed 出版商
|
| Zou Y, Wang B, Fu W, Zhou S, Nie Y, Tian S. Apelin-13 Protects PC12 Cells from Corticosterone-Induced Apoptosis Through PI3K and ERKs Activation. Neurochem Res. 2016;41:1635-44 pubmed 出版商
|
| Wang D, Wang M, Jiang N, Zhang Y, Bian X, Wang X, et al. Effective use of PI3K inhibitor BKM120 and PARP inhibitor Olaparib to treat PIK3CA mutant ovarian cancer. Oncotarget. 2016;7:13153-66 pubmed 出版商
|
| Gao L, Xu Z, Wang Y, Sun B, Song Z, Yang B, et al. Anticancer effect of SZC017, a novel derivative of oleanolic acid, on human gastric cancer cells. Oncol Rep. 2016;35:1101-8 pubmed 出版商
|
| Wang Z, Cheng Y, Yu X, Ye L, Xia Q, Johnson N, et al. bFGF Protects Against Blood-Brain Barrier Damage Through Junction Protein Regulation via PI3K-Akt-Rac1 Pathway Following Traumatic Brain Injury. Mol Neurobiol. 2016;53:7298-7311 pubmed
|
| Chen K, Dai W, Wang F, Xia Y, Li J, Li S, et al. Inhibitive effects of 15-deoxy-Δ(12),(14)-prostaglandin J2 on hepatoma-cell proliferation through reactive oxygen species-mediated apoptosis. Onco Targets Ther. 2015;8:3585-93 pubmed 出版商
|
| Dang R, Cai H, Zhang L, Liang D, Lv C, Guo Y, et al. Dysregulation of Neuregulin-1/ErbB signaling in the prefrontal cortex and hippocampus of rats exposed to chronic unpredictable mild stress. Physiol Behav. 2016;154:145-50 pubmed 出版商
|
| Xie H, Xu Z, Tang J, Du Y, Huang L, Yu P, et al. Effect of Huaier on the proliferation and apoptosis of human gastric cancer cells through modulation of the PI3K/AKT signaling pathway. Exp Ther Med. 2015;10:1212-1218 pubmed
|
| Wu J, Yang C, Guo C, Li X, Yang N, Zhao L, et al. SZC015, a synthetic oleanolic acid derivative, induces both apoptosis and autophagy in MCF-7 breast cancer cells. Chem Biol Interact. 2016;244:94-104 pubmed 出版商
|
| Yao Z, Sun B, Hong Q, Yan J, Mu D, Li J, et al. PACE4 regulates apoptosis in human prostate cancer cells via endoplasmic reticulum stress and mitochondrial signaling pathways. Drug Des Devel Ther. 2015;9:5911-23 pubmed 出版商
|
| Li Z, Yang S, Yin P, Chang T, Shi L, Fang L, et al. Activated estrogen receptor-mitogen-activated protein kinases cross talk confer acquired resistance to lapatinib. Thorac Cancer. 2015;6:695-703 pubmed 出版商
|
| Gao L, Wang Y, Xu Z, Li X, Wu J, Liu S, et al. SZC017, a novel oleanolic acid derivative, induces apoptosis and autophagy in human breast cancer cells. Apoptosis. 2015;20:1636-50 pubmed 出版商
|
| Ahsan A, Han G, Pan J, Liu S, Padhiar A, Chu P, et al. Phosphocreatine protects endothelial cells from oxidized low-density lipoprotein-induced apoptosis by modulating the PI3K/Akt/eNOS pathway. Apoptosis. 2015;20:1563-76 pubmed 出版商
|
| Zhang Q, Zhuang J, Deng Y, Zhao X, Tang B, Yao D, et al. GOLPH3 is a potential therapeutic target and a prognostic indicator of poor survival in bladder cancer treated by cystectomy. Oncotarget. 2015;6:32177-92 pubmed 出版商
|
| Lv Y, Meng B, Dong H, Jing T, Wu N, Yang Y, et al. Upregulation of GSK3β Contributes to Brain Disorders in Elderly REGγ-knockout Mice. Neuropsychopharmacology. 2016;41:1340-9 pubmed 出版商
|
| Farhan M, Carmine Simmen K, Lewis J, Moore R, Murray A. Endothelial Cell mTOR Complex-2 Regulates Sprouting Angiogenesis. PLoS ONE. 2015;10:e0135245 pubmed 出版商
|
| Wu Y, Neoh C, Tsao C, Su J, Li H. Sinulariolide Suppresses Human Hepatocellular Carcinoma Cell Migration and Invasion by Inhibiting Matrix Metalloproteinase-2/-9 through MAPKs and PI3K/Akt Signaling Pathways. Int J Mol Sci. 2015;16:16469-82 pubmed 出版商
|
| Xing S, Yang X, Zheng T, Li W, Wu D, Chi J, et al. Salidroside improves endothelial function and alleviates atherosclerosis by activating a mitochondria-related AMPK/PI3K/Akt/eNOS pathway. Vascul Pharmacol. 2015;72:141-52 pubmed 出版商
|
| Dong D, Yin L, Qi Y, Xu L, Peng J. Protective Effect of the Total Saponins from Rosa laevigata Michx Fruit against Carbon Tetrachloride-Induced Liver Fibrosis in Rats. Nutrients. 2015;7:4829-50 pubmed 出版商
|
| Wan J, Wu W, Che Y, Kang N, Zhang R. Low dose photodynamic-therapy induce immune escape of tumor cells in a HIF-1α dependent manner through PI3K/Akt pathway. Int Immunopharmacol. 2015;28:44-51 pubmed 出版商
|
| Li X, Zou K, Gou J, Du Q, Li D, He X, et al. Effect of baicalin-copper on the induction of apoptosis in human hepatoblastoma cancer HepG2 cells. Med Oncol. 2015;32:72 pubmed 出版商
|
| Sun Z, Li Q, Zhang S, Chen J, Huang L, Ren J, et al. NVP-BEZ235 overcomes gefitinib-acquired resistance by down-regulating PI3K/AKT/mTOR phosphorylation. Onco Targets Ther. 2015;8:269-77 pubmed 出版商
|
| Wang H, Shen W, Hu X, Zhang Y, Zhuo Y, Li T, et al. Quetiapine inhibits osteoclastogenesis and prevents human breast cancer-induced bone loss through suppression of the RANKL-mediated MAPK and NF-κB signaling pathways. Breast Cancer Res Treat. 2015;149:705-14 pubmed 出版商
|
| Cao G, Dong W, Meng X, Liu H, Liao H, Liu S. MiR-511 inhibits growth and metastasis of human hepatocellular carcinoma cells by targeting PIK3R3. Tumour Biol. 2015;36:4453-9 pubmed 出版商
|
| Cui M, Xiao Z, Wang Y, Zheng M, Song T, Cai X, et al. Long noncoding RNA HULC modulates abnormal lipid metabolism in hepatoma cells through an miR-9-mediated RXRA signaling pathway. Cancer Res. 2015;75:846-57 pubmed 出版商
|
| Deng S, Tang S, Zhang S, Zhang C, Wang C, Zhou Y, et al. Furazolidone induces apoptosis through activating reactive oxygen species-dependent mitochondrial signaling pathway and suppressing PI3K/Akt signaling pathway in HepG2 cells. Food Chem Toxicol. 2015;75:173-86 pubmed 出版商
|