This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.
产品简要
公司名称 :
武汉三鹰
产品类型 :
抗体
产品名称 :
P21
目录 :
10355-1-AP
规格 :
150UL
价格 :
299美元
克隆性 :
多克隆
宿主 :
domestic rabbit
共轭标签 :
未共轭
反应物种 :
人类
应用 :
免疫印迹, 酶联免疫吸附测定, 免疫组化, 免疫细胞化学, 免疫沉淀, 流式细胞仪
文章摘录数: 206
出版应用/物种/样本/稀释参考文献
  • 免疫印迹; 人类; 1:1000; 图 5b
Li K, Zhao S, Long J, Su J, Wu L, Tao J, et al. A novel chalcone derivative has antitumor activity in melanoma by inducing DNA damage through the upregulation of ROS products. Cancer Cell Int. 2020;20:36 pubmed 出版商
  • 免疫印迹; 人类; 图 6d
Wei X, Yang X, Wang B, Yang Y, Fang Z, Yi C, et al. LncRNA MBNL1-AS1 represses cell proliferation and enhances cell apoptosis via targeting miR-135a-5p/PHLPP2/FOXO1 axis in bladder cancer. Cancer Med. 2020;9:724-736 pubmed 出版商
  • 免疫印迹; 人类; 1:1000; 图 3d
Wang Q, Jia S, Jiao Y, Xu L, Wang D, Chen X, et al. SSRP1 influences colorectal cancer cell growth and apoptosis via the AKT pathway. Int J Med Sci. 2019;16:1573-1582 pubmed 出版商
  • 免疫印迹; 人类; 图 2d
Liu H, Feng X, Yang B, Tong R, Lu Y, Chen D, et al. Dimethyl fumarate suppresses hepatocellular carcinoma progression via activating SOCS3/JAK1/STAT3 signaling pathway. Am J Transl Res. 2019;11:4713-4725 pubmed
  • 免疫印迹; 人类; 1:1000; 图 6e
Sun B, Zhao X, Ming J, Liu X, Liu D, Jiang C. Stepwise detection and evaluation reveal miR-10b and miR-222 as a remarkable prognostic pair for glioblastoma. Oncogene. 2019;38:6142-6157 pubmed 出版商
  • 免疫印迹; 人类; 图 6d
Ye Z, Zeng Z, Shen Y, Yang Q, Chen D, Chen Z, et al. ODC1 promotes proliferation and mobility via the AKT/GSK3β/β-catenin pathway and modulation of acidotic microenvironment in human hepatocellular carcinoma. Onco Targets Ther. 2019;12:4081-4092 pubmed 出版商
  • 免疫印迹; 人类; 1:1000; 图 5c
Lin X, Zhan J, Zhong J, Wang Y, Wang Y, Li S, et al. lncRNA-ES3/miR-34c-5p/BMF axis is involved in regulating high-glucose-induced calcification/senescence of VSMCs. Aging (Albany NY). 2019;11:523-535 pubmed 出版商
  • 免疫印迹; 人类; 图 2
Dai Y, Wang L, Tang J, Cao P, Luo Z, Sun J, et al. Activation of anaphase-promoting complex by p53 induces a state of dormancy in cancer cells against chemotherapeutic stress. Oncotarget. 2016;7:25478-92 pubmed 出版商
Zhu X, Chen T, Yang H, Lv K. Lactate induced up-regulation of KLHDC8A (Kelch domain-containing 8A) contributes to the proliferation, migration and apoptosis of human glioma cells. J Cell Mol Med. 2020;: pubmed 出版商
Hu Z, Wang H, Fu Y, Ma K, Ma X, Wang J. Gentiopicroside Inhibits Cell Growth and Migration on Cervical Cancer via the Reciprocal MAPK/Akt Signaling Pathways. Nutr Cancer. 2020;:1-12 pubmed 出版商
Zhang D, Fan R, Lei L, Lei L, Wang Y, Lv N, et al. Cell cycle exit during bortezomib-induced osteogenic differentiation of mesenchymal stem cells was mediated by Xbp1s-upregulated p21Cip1 and p27Kip1. J Cell Mol Med. 2020;: pubmed 出版商
Yu M, Ren L, Liang F, Zhang Y, Jiang L, Ma W, et al. Effect of epiberberine from Coptis chinensis Franch on inhibition of tumor growth in MKN-45 xenograft mice. Phytomedicine. 2020;76:153216 pubmed 出版商
Jin X, Ge L, Li D, Shao Z, Di G, Xu X, et al. LncRNA TROJAN promotes proliferation and resistance to CDK4/6 inhibitor via CDK2 transcriptional activation in ER+ breast cancer. Mol Cancer. 2020;19:87 pubmed 出版商
Zhang Y, Luo L, Wang Y, Zhu N, Zhao T, Qin L. Total saponins from Lilium lancifolium: a promising alternative to inhibit the growth of gastric carcinoma cells. J Cancer. 2020;11:4261-4273 pubmed 出版商
Pereira E, Burns J, Lee C, Marohl T, Calderon D, Wang L, et al. Sporadic activation of an oxidative stress-dependent NRF2-p53 signaling network in breast epithelial spheroids and premalignancies. Sci Signal. 2020;13: pubmed 出版商
Jia Y, Jin H, Gao L, Yang X, Wang F, Ding H, et al. A novel lncRNA PLK4 up-regulated by talazoparib represses hepatocellular carcinoma progression by promoting YAP-mediated cell senescence. J Cell Mol Med. 2020;24:5304-5316 pubmed 出版商
Wang J, Li G, Ming S, Wang C, Shi L, Su B, et al. BRD4 inhibition exerts anti-viral activity through DNA damage-dependent innate immune responses. PLoS Pathog. 2020;16:e1008429 pubmed 出版商
Zhang Y, Cui N, Zheng G. Ubiquitination of P53 by E3 ligase MKRN2 promotes melanoma cell proliferation. Oncol Lett. 2020;19:1975-1984 pubmed 出版商
Wang N, Liu H, Liu G, Li M, He X, Yin C, et al. Yeast β-D-glucan exerts antitumour activity in liver cancer through impairing autophagy and lysosomal function, promoting reactive oxygen species production and apoptosis. Redox Biol. 2020;32:101495 pubmed 出版商
Wu J, Su H, Yu Z, Xi S, Guo C, Hu Z, et al. Skp2 modulates proliferation, senescence and tumorigenesis of glioma. Cancer Cell Int. 2020;20:71 pubmed 出版商
Zhao Q, Zhu H, Xie X, Mao Q, Liu Y, He X, et al. Novel HSP90-PI3K Dual Inhibitor Suppresses Melanoma Cell Proliferation by Interfering with HSP90-EGFR Interaction and Downstream Signaling Pathways. Int J Mol Sci. 2020;21: pubmed 出版商
Lin Z, Qu S, Peng W, Yang P, Zhang R, Zhang P, et al. Up-Regulated CCDC34 Contributes to the Proliferation and Metastasis of Hepatocellular Carcinoma. Onco Targets Ther. 2020;13:51-60 pubmed 出版商
Zhao H, Wang Y, Yang C, Zhou J, Wang L, Yi K, et al. EGFR-vIII downregulated H2AZK4/7AC though the PI3K/AKT-HDAC2 axis to regulate cell cycle progression. Clin Transl Med. 2020;9:10 pubmed 出版商
Auclair M, Guénantin A, Fellahi S, Garcia M, Capeau J. HIV antiretroviral drugs, dolutegravir, maraviroc and ritonavir-boosted atazanavir use different pathways to affect inflammation, senescence and insulin sensitivity in human coronary endothelial cells. PLoS ONE. 2020;15:e0226924 pubmed 出版商
Masre S, Rath N, Olson M, Greenhalgh D. Epidermal ROCK2-induces AKT1/GSK3β/β-catenin, NFκB and dermal tenascin-C; but enhanced differentiation and p53/p21 inhibit papilloma. Carcinogenesis. 2020;: pubmed 出版商
Wang J, Li S, Wang J, Wu F, Chen Y, Zhang H, et al. Spermidine alleviates cardiac aging by improving mitochondrial biogenesis and function. Aging (Albany NY). 2020;12:650-671 pubmed 出版商
Du X, Tu Y, Liu S, Zhao P, Bao Z, Li C, et al. LINC00511 contributes to glioblastoma tumorigenesis and epithelial-mesenchymal transition via LINC00511/miR-524-5p/YB1/ZEB1 positive feedback loop. J Cell Mol Med. 2020;24:1474-1487 pubmed 出版商
Li F, Zhao F, Li M, Pan M, Shi F, Xu H, et al. Decreasing New York esophageal squamous cell carcinoma 1 expression inhibits multiple myeloma growth and osteolytic lesions. J Cell Physiol. 2020;235:2183-2194 pubmed 出版商
Guo S, Jian L, Tao K, Chen C, Yu H, Liu S. Novel Breast-Specific Long Non-coding RNA LINC00993 Acts as a Tumor Suppressor in Triple-Negative Breast Cancer. Front Oncol. 2019;9:1325 pubmed 出版商
Zhao J, Honda Y, Tanaka T, Hashimoto Y, Matsumoto N. Releasing Behavior of Lipopolysaccharide from Gelatin Modulates Inflammation, Cellular Senescence, and Bone Formation in Critical-Sized Bone Defects in Rat Calvaria. Materials (Basel). 2019;13: pubmed 出版商
Wu Z, Chen D, Wang K, Cao C, Xu X. Long Non-coding RNA SNHG12 Functions as a Competing Endogenous RNA to Regulate MDM4 Expression by Sponging miR-129-5p in Clear Cell Renal Cell Carcinoma. Front Oncol. 2019;9:1260 pubmed 出版商
Li Y, Li X, Cao M, Jiang Y, Yan J, Liu Z, et al. Seryl tRNA synthetase cooperates with POT1 to regulate telomere length and cellular senescence. Signal Transduct Target Ther. 2019;4:50 pubmed 出版商
Li F, Su M, Zhao H, Xie W, Cao S, Xu Y, et al. HnRNP-F promotes cell proliferation by regulating TPX2 in bladder cancer. Am J Transl Res. 2019;11:7035-7048 pubmed
Li Y, Zu X, Hu X, Wang L, He W. Forkhead Box R2 Knockdown Decreases Chemoresistance to Cisplatin via MYC Pathway in Bladder Cancer. Med Sci Monit. 2019;25:8928-8939 pubmed 出版商
Chen J, Sun X, Mao Q, Jiang X, Zhao X, Xu W, et al. Increased expression of hematological and neurological expressed 1 (HN1) is associated with a poor prognosis of hepatocellular carcinoma and its knockdown inhibits cell growth and migration partly by down-regulation of c-Met. Kaohsiung J Med Sci. 2019;: pubmed 出版商
Wu J, Lu K, Zhu M, Xie X, Ding Y, Shao X, et al. miR-485 suppresses inflammation and proliferation of mesangial cells in an in vitro model of diabetic nephropathy by targeting NOX5. Biochem Biophys Res Commun. 2019;: pubmed 出版商
Liu L, Wang F, Tong Y, Li L, Liu Y, Gao W. Pentamidine inhibits prostate cancer progression via selectively inducing mitochondrial DNA depletion and dysfunction. Cell Prolif. 2019;:e12718 pubmed 出版商
Xue Y, Lian W, Zhi J, Yang W, Li Q, Guo X, et al. HDAC5-mediated deacetylation and nuclear localisation of SOX9 is critical for tamoxifen resistance in breast cancer. Br J Cancer. 2019;121:1039-1049 pubmed 出版商
Zhao X, Zhang C, Wei X, Shi L, Dai S, Jia J, et al. CARLo-5 as an oncogenic gene in endometrial carcinoma. Environ Mol Mutagen. 2019;: pubmed 出版商
Hu Y, Ma S, Zhang X, Zhang Z, Zhu H, Ji Y, et al. Hypermethylation Of ADHFE1 Promotes The Proliferation Of Colorectal Cancer Cell Via Modulating Cell Cycle Progression. Onco Targets Ther. 2019;12:8105-8115 pubmed 出版商
Li S, Han J, Guo G, Sun Y, Zhang T, Zhao M, et al. Voltage-gated sodium channels β3 subunit promotes tumorigenesis in hepatocellular carcinoma by facilitating p53 degradation. FEBS Lett. 2019;: pubmed 出版商
Liu L, Zhu J, Yu X, Zhu H, Shi X, Bilegsaikhan E, et al. UBE2T promotes proliferation via G2/M checkpoint in hepatocellular carcinoma. Cancer Manag Res. 2019;11:8359-8370 pubmed 出版商
Tian S, Feng J, Cao Y, Shen S, Cai Y, Yang D, et al. Glycine cleavage system determines the fate of pluripotent stem cells via the regulation of senescence and epigenetic modifications. Life Sci Alliance. 2019;2: pubmed 出版商
Gao X, Zhang Y, Zhang R, Zhao Z, Zhang H, Wu J, et al. Cyclin-dependent kinase 1 disruption inhibits angiogenesis by inducing cell cycle arrest and apoptosis. Exp Ther Med. 2019;18:3062-3070 pubmed 出版商
Pan C, Lang H, Zhang T, Wang R, Lin X, Shi P, et al. Conditioned medium derived from human amniotic stem cells delays H2O2‑induced premature senescence in human dermal fibroblasts. Int J Mol Med. 2019;44:1629-1640 pubmed 出版商
Zhang Z, Li X, Han Y, Ji T, Huang X, Gao Q, et al. RAD54B potentiates tumor growth and predicts poor prognosis of patients with luminal A breast cancer. Biomed Pharmacother. 2019;118:109341 pubmed 出版商
Wei C, Zhang R, Cai Q, Gao X, Tong F, Dong J, et al. MicroRNA-330-3p promotes brain metastasis and epithelial-mesenchymal transition via GRIA3 in non-small cell lung cancer. Aging (Albany NY). 2019;11:6734-6761 pubmed 出版商
He J, Hong B, Bian M, Jin H, Chen J, Shao J, et al. Docosahexaenoic acid inhibits hepatic stellate cell activation to attenuate liver fibrosis in a PPARγ-dependent manner. Int Immunopharmacol. 2019;75:105816 pubmed 出版商
Sun S, Hu Z, Huang S, Ye X, Wang J, Chang J, et al. REG4 is an indicator for KRAS mutant lung adenocarcinoma with TTF-1 low expression. J Cancer Res Clin Oncol. 2019;145:2273-2283 pubmed 出版商
Guo J, Wang Q, Zhang Y, Sun W, Zhang S, Li Y, et al. Functional daidzein enhances the anticancer effect of topotecan and reverses BCRP-mediated drug resistance in breast cancer. Pharmacol Res. 2019;147:104387 pubmed 出版商
Que Z, Zhou Z, Luo B, Dong C, Jiang Y, Li H, et al. Jingfukang induces anti-cancer activity through oxidative stress-mediated DNA damage in circulating human lung cancer cells. BMC Complement Altern Med. 2019;19:204 pubmed 出版商
Fan X, Wang Y, Song J, Wu H, Yang M, Lu L, et al. MDM2 inhibitor RG7388 potently inhibits tumors by activating p53 pathway in nasopharyngeal carcinoma. Cancer Biol Ther. 2019;:1-9 pubmed 出版商
Liu Y, Fan D. Ginsenoside Rg5 induces G2/M phase arrest, apoptosis and autophagy via regulating ROS-mediated MAPK pathways against human gastric cancer. Biochem Pharmacol. 2019;168:285-304 pubmed 出版商
Li S, Yao M, Niu C, Liu D, Tang Z, Gu C, et al. Inhibition of MCF-7 breast cancer cell proliferation by a synthetic peptide derived from the C-terminal sequence of Orai channel. Biochem Biophys Res Commun. 2019;516:1066-1072 pubmed 出版商
Yang B, Wu A, Hu Y, Tao C, Wang J, Lu Y, et al. Mucin 17 inhibits the progression of human gastric cancer by limiting inflammatory responses through a MYH9-p53-RhoA regulatory feedback loop. J Exp Clin Cancer Res. 2019;38:283 pubmed 出版商
Gao F, Liang Y, Zhou P, Cheng J, Ding K, Wang Y. Design, synthesis, antitumor activities and biological studies of novel diaryl substituted fused heterocycles as dual ligands targeting tubulin and katanin. Eur J Med Chem. 2019;178:177-194 pubmed 出版商
Zhou W, Ma L, Yang J, Qiao H, Li L, Guo Q, et al. Potent and specific MTH1 inhibitors targeting gastric cancer. Cell Death Dis. 2019;10:434 pubmed 出版商
Wang S, Wang W, Liu J, Song Y, Li P, Sun X, et al. Methionine restriction delays senescence and suppresses the senescence-associated secretory phenotype in the kidney through endogenous hydrogen sulfide. Cell Cycle. 2019;18:1573-1587 pubmed 出版商
Luo Y, Xie C, Brocker C, Fan J, Wu X, Feng L, et al. Intestinal PPARα Protects Against Colon Carcinogenesis via Regulation of Methyltransferases DNMT1 and PRMT6. Gastroenterology. 2019;: pubmed 出版商
Zheng M, Tian C, Fan T, Xu B. Fibronectin regulates the self-renewal of rabbit limbal epithelial stem cells by stimulating the Wnt11/Fzd7/ROCK non-canonical Wnt pathway. Exp Eye Res. 2019;185:107681 pubmed 出版商
Wang S, Wang H, Sun B, Li D, Wu J, Li J, et al. Acetyl-11-keto-β-boswellic acid triggers premature senescence via induction of DNA damage accompanied by impairment of DNA repair genes in hepatocellular carcinoma cells in vitro and in vivo. Fundam Clin Pharmacol. 2019;: pubmed 出版商
Yu H, Sun L, Cui J, Li Y, Yan Y, Wei X, et al. Three kinds of corneal host cells contribute differently to corneal neovascularization. EBioMedicine. 2019;: pubmed 出版商
Liu H, Zhao J, Fu R, Zhu C, Fan D. The ginsenoside Rk3 exerts anti-esophageal cancer activity in vitro and in vivo by mediating apoptosis and autophagy through regulation of the PI3K/Akt/mTOR pathway. PLoS ONE. 2019;14:e0216759 pubmed 出版商
Yan Y, Yu H, Sun L, Liu H, Wang C, Wei X, et al. Laminin α4 overexpression in the anterior lens capsule may contribute to the senescence of human lens epithelial cells in age-related cataract. Aging (Albany NY). 2019;11:2699-2723 pubmed 出版商
Sui Y, Wu T, Li F, Wang F, Cai Y, Jin J. YY1/BCCIP Coordinately Regulates P53-Responsive Element (p53RE)-Mediated Transactivation of p21Waf1/Cip1. Int J Mol Sci. 2019;20: pubmed 出版商
Li N, Piao J, Wang X, Kim K, Bae J, Ren X, et al. Paip1 Indicated Poor Prognosis in Cervical Cancer and Promoted Cervical Carcinogenesis. Cancer Res Treat. 2019;: pubmed 出版商
Sun J, Zhang H, Tao D, Xie F, Liu F, Gu C, et al. CircCDYL inhibits the expression of C-MYC to suppress cell growth and migration in bladder cancer. Artif Cells Nanomed Biotechnol. 2019;47:1349-1356 pubmed 出版商
Qin F, Wang Y, Jiang X, Wang Y, Zhang N, Wen X, et al. Design, synthesis and molecular mechanisms of novel dual inhibitors of heat shock protein 90/phosphoinositide 3-kinase alpha (Hsp90/PI3Kα) against cutaneous melanoma. J Enzyme Inhib Med Chem. 2019;34:909-926 pubmed 出版商
Li X, Wu J, Liu S, Zhang K, Miao X, Li J, et al. miR-384-5p Targets Gli2 and Negatively Regulates Age-Related Osteogenic Differentiation of Rat Bone Marrow Mesenchymal Stem Cells. Stem Cells Dev. 2019;28:791-798 pubmed 出版商
Shen Z, Liao X, Shao Z, Feng M, Yuan J, Wang S, et al. Short-term stimulation with histone deacetylase inhibitor trichostatin a induces epithelial-mesenchymal transition in nasopharyngeal carcinoma cells without increasing cell invasion ability. BMC Cancer. 2019;19:262 pubmed 出版商
Qin H, Li Y, Zhang H, Wang F, He H, Bai X, et al. Prognostic implications and oncogenic roles of MYBL2 protein expression in esophageal squamous-cell carcinoma. Onco Targets Ther. 2019;12:1917-1927 pubmed 出版商
Zhao Z, Li L, Du P, Ma L, Zhang W, Zheng L, et al. Transcriptional Downregulation of miR-4306 serves as a New Therapeutic Target for Triple Negative Breast Cancer. Theranostics. 2019;9:1401-1416 pubmed 出版商
Bie Y, Gu P, Chen Y, Zhou X, Tian Y, Yang Q, et al. TZAP plays an inhibitory role in the self-renewal of porcine mesenchymal stromal cells and is implicated the regulation of premature senescence via the p53 pathway. J Transl Med. 2019;17:72 pubmed 出版商
Wang D, Li W, Zhao R, Chen L, Liu N, Tian Y, et al. Stabilized Peptide HDAC Inhibitors Derived from HDAC1 Substrate H3K56 for the Treatment of Cancer Stem-Like Cells In Vivo. Cancer Res. 2019;79:1769-1783 pubmed 出版商
Sui A, Xu Y, Pan B, Guo T, Wu J, Shen Y, et al. Histone demethylase KDM6B regulates 1,25-dihydroxyvitamin D3-induced senescence in glioma cells. J Cell Physiol. 2019;: pubmed 出版商
Sun X, Xie Y, Sun X, Yao Y, Li H, Li Z, et al. The selective HDAC6 inhibitor Nexturastat A induces apoptosis, overcomes drug resistance and inhibits tumor growth in multiple myeloma. Biosci Rep. 2019;: pubmed 出版商
Peng W, Tong C, Li L, Huang C, Ran Y, Chen X, et al. Trophoblastic proliferation and invasion regulated by ACTN4 is impaired in early onset preeclampsia. FASEB J. 2019;33:6327-6338 pubmed 出版商
Wudu M, Ren H, Hui L, Jiang J, Zhang S, Xu Y, et al. DRAM2 acts as an oncogene in non-small cell lung cancer and suppresses the expression of p53. J Exp Clin Cancer Res. 2019;38:72 pubmed 出版商
Gu X, Wang Z, Gao J, Han D, Zhang L, Chen P, et al. SIRT1 suppresses p53-dependent apoptosis by modulation of p21 in osteoblast-like MC3T3-E1 cells exposed to fluoride. Toxicol In Vitro. 2019;57:28-38 pubmed 出版商
Chen L, He P, Yang J, Yang Y, Wang K, Amend B, et al. NLRP3/IL1β inflammasome associated with the aging bladder triggers bladder dysfunction in female rats. Mol Med Rep. 2019;19:2960-2968 pubmed 出版商
Han Y, Wu P, Wang Z, Zhang Z, Sun S, Liu J, et al. Ubiquinol-cytochrome C reductase core protein II promotes tumorigenesis by facilitating p53 degradation. EBioMedicine. 2019;40:92-105 pubmed 出版商
Zhou Y, Niu W, Luo Y, Li H, Xie Y, Wang H, et al. The p53/LDHA axis negatively regulates aerobic glycolysis and tumor progression in breast cancer expressing wild-type p53. Cancer Sci. 2019;: pubmed 出版商
Wei X, Luo D, Yan Y, Yu H, Sun L, Wang C, et al. Kojic acid inhibits senescence of human corneal endothelial cells via NF-κB and p21 signaling pathways. Exp Eye Res. 2019;180:174-183 pubmed 出版商
Liang X, Ding Y, Lin F, Zhang Y, Zhou X, Meng Q, et al. Overexpression of ERBB4 rejuvenates aged mesenchymal stem cells and enhances angiogenesis via PI3K/AKT and MAPK/ERK pathways. FASEB J. 2019;33:4559-4570 pubmed 出版商
Guo J, Tang Q, Wang Q, Sun W, Pu Z, Wang J, et al. Pifithrin-α enhancing anticancer effect of topotecan on p53-expressing cancer cells. Eur J Pharm Sci. 2019;128:61-72 pubmed 出版商
Cui D, Zhao Y, Xu J. Activation of CXCL5-CXCR2 axis promotes proliferation and accelerates G1 to S phase transition of papillary thyroid carcinoma cells and activates JNK and p38 pathways. Cancer Biol Ther. 2019;20:608-616 pubmed 出版商
Pan J, Zhou H, Zhu S, Huang J, Zhao X, Ding H, et al. Nicotinamide phosphoribosyl transferase regulates cell growth via the Sirt1/P53 signaling pathway and is a prognosis marker in colorectal cancer. J Cell Physiol. 2019;234:4385-4395 pubmed 出版商
Chen Y, Tzeng D, Huang Y, Lin C, Lo U, Wu C, et al. Antrocin Sensitizes Prostate Cancer Cells to Radiotherapy through Inhibiting PI3K/AKT and MAPK Signaling Pathways. Cancers (Basel). 2018;11: pubmed 出版商
Wang L, Han X, Qu G, Su L, Zhao B, Miao J. A pH probe inhibits senescence in mesenchymal stem cells. Stem Cell Res Ther. 2018;9:343 pubmed 出版商
Fan Y, Mao Y, Cao S, Xia G, Zhang Q, Zhang H, et al. S5, a Withanolide Isolated from Physalis Pubescens L., Induces G2/M Cell Cycle Arrest via the EGFR/P38 Pathway in Human Melanoma A375 Cells. Molecules. 2018;23: pubmed 出版商
Chen M, Zhang H, Zhang G, Zhong A, Ma Q, Kai J, et al. Targeting TPX2 suppresses proliferation and promotes apoptosis via repression of the PI3k/AKT/P21 signaling pathway and activation of p53 pathway in breast cancer. Biochem Biophys Res Commun. 2018;507:74-82 pubmed 出版商
Liu L, Sun Y, Zhao Y, Wang Q, Guo H, Guo R, et al. Urea transport B gene induces melanoma B16 cell death via activation of p53 and mitochondrial apoptosis. Cancer Sci. 2018;109:3762-3773 pubmed 出版商
Xie F, Li Y, Wang M, Huang C, Tao D, Zheng F, et al. Circular RNA BCRC-3 suppresses bladder cancer proliferation through miR-182-5p/p27 axis. Mol Cancer. 2018;17:144 pubmed 出版商
Wen W, Chen J, Ding L, Luo X, Zheng X, Dai Q, et al. Astragaloside exerts anti-photoaging effects in UVB-induced premature senescence of rat dermal fibroblasts through enhanced autophagy. Arch Biochem Biophys. 2018;657:31-40 pubmed 出版商
Yu M, Wang H, Liu J, Qin H, Liu S, Yan Q. The sialyltransferase ST3Gal3 facilitates the receptivity of the uterine endometrium in vitro and in vivo. FEBS Lett. 2018;592:3696-3707 pubmed 出版商
Chen X, Liu C, Zhao R, Zhao P, Wu J, Zhou N, et al. Synergetic and Antagonistic Molecular Effects Mediated by the Feedback Loop of p53 and JNK between Saikosaponin D and SP600125 on Lung Cancer A549 Cells. Mol Pharm. 2018;15:4974-4984 pubmed 出版商
Wang Z, Wang Y, Wang S, Meng X, Song F, Huo W, et al. Coxsackievirus A6 Induces Cell Cycle Arrest in G0/G1 Phase for Viral Production. Front Cell Infect Microbiol. 2018;8:279 pubmed 出版商
Li Z, Qiu R, Qiu X, Tian T. SNHG6 Promotes Tumor Growth via Repression of P21 in Colorectal Cancer. Cell Physiol Biochem. 2018;49:463-478 pubmed 出版商
Napoli E, Song G, Panoutsopoulos A, Riyadh M, Kaushik G, Halmai J, et al. Beyond autophagy: a novel role for autism-linked Wdfy3 in brain mitophagy. Sci Rep. 2018;8:11348 pubmed 出版商
Luo W, Wang Y, Yang H, Dai C, Hong H, Li J, et al. Heme oxygenase-1 ameliorates oxidative stress-induced endothelial senescence via regulating endothelial nitric oxide synthase activation and coupling. Aging (Albany NY). 2018;10:1722-1744 pubmed 出版商
Badi I, Mancinelli L, Polizzotto A, Ferri D, Zeni F, Burba I, et al. miR-34a Promotes Vascular Smooth Muscle Cell Calcification by Downregulating SIRT1 (Sirtuin 1) and Axl (AXL Receptor Tyrosine Kinase). Arterioscler Thromb Vasc Biol. 2018;38:2079-2090 pubmed 出版商
Huang B, Lv D, Wang C, Shu F, Gong Z, Xie T, et al. Suppressed epithelial-mesenchymal transition and cancer stem cell properties mediate the anti-cancer effects of ethyl pyruvate via regulation of the AKT/nuclear factor-?B pathway in prostate cancer cells. Oncol Lett. 2018;16:2271-2278 pubmed 出版商
Yang H, Hong H, Luo W, Dai C, Chen X, Wang L, et al. mTORC2 facilitates endothelial cell senescence by suppressing Nrf2 expression via the Akt/GSK-3β/C/EBPα signaling pathway. Acta Pharmacol Sin. 2018;39:1837-1846 pubmed 出版商
Chen S, Lin T, Tseng Y, Tu C, Lui T, Huang S, et al. Targeting inhibitors of apoptosis proteins suppresses medulloblastoma cell proliferation via G2/M phase arrest and attenuated neddylation of p21. Cancer Med. 2018;7:3988-4003 pubmed 出版商
Liu L, Sun X, Xie Y, Zhuang Y, Yao R, Xu K. Anticancer effect of histone deacetylase inhibitor scriptaid as a single agent for hepatocellular carcinoma. Biosci Rep. 2018;38: pubmed 出版商
Liu X, Zhao Y, Zhang W, Gao Y, Huo M, Liu M, et al. Inhibition of survivin enhances radiosensitivity of esophageal cancer cells by switching radiation-induced senescence to apoptosis. Onco Targets Ther. 2018;11:3087-3100 pubmed 出版商
Xue X, Wang X, Zhao Y, Hu R, Qin L. Exosomal miR-93 promotes proliferation and invasion in hepatocellular carcinoma by directly inhibiting TIMP2/TP53INP1/CDKN1A. Biochem Biophys Res Commun. 2018;502:515-521 pubmed 出版商
Ling Z, Guan H, You Z, Wang C, Hu L, Zhang L, et al. Aloperine executes antitumor effects through the induction of apoptosis and cell cycle arrest in prostate cancer in vitro and in vivo. Onco Targets Ther. 2018;11:2735-2743 pubmed 出版商
Wu F, Li S, Zhang N, Huang W, Li X, Wang M, et al. Hispidulin alleviates high-glucose-induced podocyte injury by regulating protective autophagy. Biomed Pharmacother. 2018;104:307-314 pubmed 出版商
Jiang B, Zhao W, Shi M, Zhang J, Chen A, Ma H, et al. IDH1 Arg-132 mutant promotes tumor formation through down-regulating p53. J Biol Chem. 2018;293:9747-9758 pubmed 出版商
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产品信息
目录号 :
10355-1-AP
AntigenName :
P21
Package :
150UL
价格 :
299美元
Exsists20ul :
20ul trial size available
FullName :
cyclin-dependent kinase inhibitor 1A (p21, Cip1)
免疫原 :
重组蛋白
物种 :
artemia sinica, human, mouse, rat, swine
宿主 :
IsConjugated :
未共轭
AntigenSpecies :
人类
应用 :
免疫印迹, 免疫沉淀, 免疫组化, IF, FC, 酶联免疫吸附测定
Clonlity :
多克隆
抗体亚型 :
IgG
同义词 :
CAP20, CDK interacting protein 1, CDKN1, CDKN1A, CIP1, MDA 6, MDA6, P21, p21CIP1, PIC1, SDI1, WAF1
PrimaryOrSecondary :
Primary
抗体缓冲液 :
PBS with 0.02% sodium azide and 50% glycerol pH 7.3.
GenBank登录号 :
BC000275
类别 :
Binding Proteins;Cell Cycle;Cytoskeleton/Scaffold Proteins;Disease Related;Metabolism;Oncogene(s) and Tumor Suppressor(s);Senescence;
PurifyMethod :
抗原亲和纯化
NewAb :
False
IsSellable :
True
Feature :
siRNA
AppTiter :
IF 1:50;免疫组化1:400;免疫沉淀1:1000;免疫印迹1:800;
公司信息
武汉三鹰
武汉市洪山区关山二路关东科技园7-4#,402室
Service@ptglab.com
http://www.ptgcn.com
4006 900 926, 027-87531629 / 027-87531627
公司总部: 美国
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