This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.
产品简要
公司名称 :
武汉三鹰
产品类型 :
抗体
产品名称 :
TDP-43
目录 :
10782-2-AP
规格 :
150UL
价格 :
299美元
克隆性 :
多克隆
宿主 :
domestic rabbit
共轭标签 :
未共轭
反应物种 :
人类, 小鼠, 大鼠, brewer's yeast, fruit fly
应用 :
免疫印迹, 酶联免疫吸附测定, 免疫组化, 免疫细胞化学, 免疫沉淀, 流式细胞仪, 染色质免疫沉淀 , 免疫组化-石蜡切片, 免疫组化-自由浮动切片, proximity ligation assay, 核糖核酸免疫沉淀, 免疫组化基因敲除验证
文章摘录数: 416
出版应用/物种/样本/稀释参考文献
  • 免疫组化-石蜡切片; 人类; 1:1000; 图 3e
Lloyd G, Trejo Lopez J, Xia Y, McFarland K, Lincoln S, Ertekin Taner N, et al. Prominent amyloid plaque pathology and cerebral amyloid angiopathy in APP V717I (London) carrier - phenotypic variability in autosomal dominant Alzheimer's disease. Acta Neuropathol Commun. 2020;8:31 pubmed 出版商
  • 核糖核酸免疫沉淀; 大鼠; 图 5h
Keihani S, Kluever V, Mandad S, Bansal V, Rahman R, Fritsch E, et al. The long noncoding RNA neuroLNC regulates presynaptic activity by interacting with the neurodegeneration-associated protein TDP-43. Sci Adv. 2019;5:eaay2670 pubmed 出版商
  • proximity ligation assay; 人类; 图 2b
  • 免疫细胞化学; 人类; 图 2d
Wheeler J, McMillan P, Strovas T, Liachko N, Amlie Wolf A, Kow R, et al. Activity of the poly(A) binding protein MSUT2 determines susceptibility to pathological tau in the mammalian brain. Sci Transl Med. 2019;11: pubmed 出版商
  • 免疫组化基因敲除验证; 小鼠; 1:1000; 图 8d
Araki K, Araki A, Honda D, Izumoto T, Hashizume A, Hijikata Y, et al. TDP-43 regulates early-phase insulin secretion via CaV1.2-mediated exocytosis in islets. J Clin Invest. 2019;130:3578-3593 pubmed 出版商
  • 免疫组化-自由浮动切片; 小鼠; 1:200; 图 5
  • 免疫印迹; 小鼠; 1:1000; 图 7a
Duan W, Guo M, Yi L, Zhang J, Bi Y, Liu Y, et al. Deletion of Tbk1 disrupts autophagy and reproduces behavioral and locomotor symptoms of FTD-ALS in mice. Aging (Albany NY). 2019;11:2457-2476 pubmed 出版商
  • 免疫印迹; fruit fly ; 1:1000; 图 2b
Berson A, Goodman L, Sartoris A, Otte C, Aykit J, Lee V, et al. Drosophila Ref1/ALYREF regulates transcription and toxicity associated with ALS/FTD disease etiologies. Acta Neuropathol Commun. 2019;7:65 pubmed 出版商
  • 免疫组化-石蜡切片; 人类; 1:5000; 图 s8
  • 免疫细胞化学; 人类; 1:1000; 图 1e
  • 免疫印迹; 人类; 1:1000; 图 1d
Melamed Z, López Erauskin J, Baughn M, Zhang O, Drenner K, Sun Y, et al. Premature polyadenylation-mediated loss of stathmin-2 is a hallmark of TDP-43-dependent neurodegeneration. Nat Neurosci. 2019;22:180-190 pubmed 出版商
  • 免疫组化-石蜡切片; 小鼠; 图 9c
Kuliyev E, Gingras S, Guy C, Howell S, Vogel P, Pelletier S. Overlapping Role of SCYL1 and SCYL3 in Maintaining Motor Neuron Viability. J Neurosci. 2018;38:2615-2630 pubmed 出版商
  • 免疫细胞化学; 大鼠; 图 8a
  • 免疫印迹; 大鼠; 1:1000; 图 8b
Gemechu J, Sharma A, Yu D, Xie Y, Merkel O, Moszczynska A. Characterization of Dopaminergic System in the Striatum of Young Adult Park2-/- Knockout Rats. Sci Rep. 2018;8:1517 pubmed 出版商
  • 免疫细胞化学; 大鼠; 图 1a
Herzog J, Deshpande M, Shapiro L, Rodal A, Paradis S. TDP-43 misexpression causes defects in dendritic growth. Sci Rep. 2017;7:15656 pubmed 出版商
  • 免疫组化; 人类; 1:100; 图 s3b
Krug L, Chatterjee N, Borges Monroy R, Hearn S, Liao W, Morrill K, et al. Retrotransposon activation contributes to neurodegeneration in a Drosophila TDP-43 model of ALS. PLoS Genet. 2017;13:e1006635 pubmed 出版商
  • 免疫细胞化学; 人类; 1:500; 图 3a
  • 免疫印迹; 人类; 1:5000; 图 4a
Wobst H, Wesolowski S, Chadchankar J, Delsing L, Jacobsen S, Mukherjee J, et al. Cytoplasmic Relocalization of TAR DNA-Binding Protein 43 Is Not Sufficient to Reproduce Cellular Pathologies Associated with ALS In vitro. Front Mol Neurosci. 2017;10:46 pubmed 出版商
  • 免疫细胞化学; 人类; 图 s9d
Shadle S, Zhong J, Campbell A, Conerly M, Jagannathan S, Wong C, et al. DUX4-induced dsRNA and MYC mRNA stabilization activate apoptotic pathways in human cell models of facioscapulohumeral dystrophy. PLoS Genet. 2017;13:e1006658 pubmed 出版商
  • 免疫组化基因敲除验证; 小鼠; 1:500; 图 1b
Laclair K, Donde A, Ling J, Jeong Y, Chhabra R, Martin L, et al. Depletion of TDP-43 decreases fibril and plaque β-amyloid and exacerbates neurodegeneration in an Alzheimer's mouse model. Acta Neuropathol. 2016;132:859-873 pubmed
  • 免疫细胞化学; 人类; 图 5a
Lee K, Zhang P, Kim H, Mitrea D, Sarkar M, Freibaum B, et al. C9orf72 Dipeptide Repeats Impair the Assembly, Dynamics, and Function of Membrane-Less Organelles. Cell. 2016;167:774-788.e17 pubmed 出版商
  • 免疫细胞化学; 人类; 1:500; 图 5c
Smethurst P, Newcombe J, Troakes C, Simone R, Chen Y, Patani R, et al. In vitro prion-like behaviour of TDP-43 in ALS. Neurobiol Dis. 2016;96:236-247 pubmed 出版商
  • 免疫印迹; 人类; 1:2000; 图 6d
Kapeli K, Pratt G, Vu A, Hutt K, Martinez F, Sundararaman B, et al. Distinct and shared functions of ALS-associated proteins TDP-43, FUS and TAF15 revealed by multisystem analyses. Nat Commun. 2016;7:12143 pubmed 出版商
  • 免疫沉淀; 小鼠; 图 1
  • 免疫印迹; 小鼠; 1:1000; 图 1
Li R, Dong Q, Yuan X, Zeng X, Gao Y, Chiao C, et al. Misregulation of Alternative Splicing in a Mouse Model of Rett Syndrome. PLoS Genet. 2016;12:e1006129 pubmed 出版商
  • 免疫组化; 小鼠; 1:100
Vernay A, Therreau L, Blot B, Risson V, Dirrig Grosch S, Waegaert R, et al. A transgenic mouse expressing CHMP2Bintron5 mutant in neurons develops histological and behavioural features of amyotrophic lateral sclerosis and frontotemporal dementia. Hum Mol Genet. 2016;25:3341-3360 pubmed 出版商
  • 免疫组化-石蜡切片; 人类; 图 1
Ando K, Tomimura K, Sazdovitch V, Suain V, Yilmaz Z, Authelet M, et al. Level of PICALM, a key component of clathrin-mediated endocytosis, is correlated with levels of phosphotau and autophagy-related proteins and is associated with tau inclusions in AD, PSP and Pick disease. Neurobiol Dis. 2016;94:32-43 pubmed 出版商
  • 免疫印迹; 人类; 1:500; 图 5
Onesto E, Colombrita C, Gumina V, Borghi M, Dusi S, Doretti A, et al. Gene-specific mitochondria dysfunctions in human TARDBP and C9ORF72 fibroblasts. Acta Neuropathol Commun. 2016;4:47 pubmed 出版商
  • 免疫细胞化学; 人类; 图 8
  • 免疫印迹; 人类; 图 3
Alquezar C, Salado I, de la Encarnación A, Perez D, Moreno F, Gil C, et al. Targeting TDP-43 phosphorylation by Casein Kinase-1? inhibitors: a novel strategy for the treatment of frontotemporal dementia. Mol Neurodegener. 2016;11:36 pubmed 出版商
  • 免疫组化-石蜡切片; 小鼠; 图 s3g
O Rourke J, Bogdanik L, Yáñez A, Lall D, Wolf A, Muhammad A, et al. C9orf72 is required for proper macrophage and microglial function in mice. Science. 2016;351:1324-9 pubmed 出版商
  • 免疫印迹; 小鼠; 1:10,000; 图 6
Sharma A, Lyashchenko A, Lu L, Nasrabady S, Elmaleh M, Mendelsohn M, et al. ALS-associated mutant FUS induces selective motor neuron degeneration through toxic gain of function. Nat Commun. 2016;7:10465 pubmed 出版商
  • 免疫印迹; brewer's yeast; 图 3
Torrente M, Chuang E, Noll M, Jackrel M, Go M, Shorter J. Mechanistic Insights into Hsp104 Potentiation. J Biol Chem. 2016;291:5101-15 pubmed 出版商
Venkataraman L, He P, Khan G, Harris B, Sierks M. Isolation and characterization of antibody fragments selective for human FTD brain derived TDP-43 variants. BMC Neurosci. 2020;21:36 pubmed 出版商
Neumann M, Frick P, Paron F, Kosten J, Buratti E, Mackenzie I. Antibody against TDP-43 phosphorylated at serine 375 suggests conformational differences of TDP-43 aggregates among FTLD-TDP subtypes. Acta Neuropathol. 2020;: pubmed 出版商
Bajc Česnik A, Motaln H, Rogelj B. The Impact of ALS-Associated Genes hnRNPA1, MATR3, VCP and UBQLN2 on the Severity of TDP-43 Aggregation. Cells. 2020;9: pubmed 出版商
Briese M, Saal Bauernschubert L, Lüningschrör P, Moradi M, Dombert B, Surrey V, et al. Loss of Tdp-43 disrupts the axonal transcriptome of motoneurons accompanied by impaired axonal translation and mitochondria function. Acta Neuropathol Commun. 2020;8:116 pubmed 出版商
Zhu Y, Liu Y, Yang F, Chen W, Jiang J, He P, et al. All-Trans Retinoic Acid Exerts Neuroprotective Effects in Amyotrophic Lateral Sclerosis-Like Tg (SOD1*G93A)1Gur Mice. Mol Neurobiol. 2020;57:3603-3615 pubmed 出版商
Wu H, Sun H, He Z, Chen X, Li Y, Zhao X, et al. The effect and mechanism of 19S proteasome PSMD11/Rpn6 subunit in D-Galactose induced mimetic aging models. Exp Cell Res. 2020;394:112093 pubmed 出版商
Sanna S, Esposito S, Masala A, Sini P, Nieddu G, Galioto M, et al. HDAC1 inhibition ameliorates TDP-43-induced cell death in vitro and in vivo. Cell Death Dis. 2020;11:369 pubmed 出版商
Tasca G, Lattante S, Marangi G, Conte A, Bernardo D, Bisogni G, et al. SOD1 p.D12Y variant is associated with amyotrophic lateral sclerosis/distal myopathy spectrum. Eur J Neurol. 2020;27:1304-1309 pubmed 出版商
Dobson Stone C, Hallupp M, Shahheydari H, Ragagnin A, Chatterton Z, Carew Jones F, et al. CYLD is a causative gene for frontotemporal dementia - amyotrophic lateral sclerosis. Brain. 2020;143:783-799 pubmed 出版商
Martínez González L, Rodríguez Cueto C, Cabezudo D, Bartolomé F, Andrés Benito P, Ferrer I, et al. Motor neuron preservation and decrease of in vivo TDP-43 phosphorylation by protein CK-1δ kinase inhibitor treatment. Sci Rep. 2020;10:4449 pubmed 出版商
Ormeño F, Hormazabal J, Moreno J, Riquelme F, Rios J, Criollo A, et al. Chaperone Mediated Autophagy Degrades TDP-43 Protein and Is Affected by TDP-43 Aggregation. Front Mol Neurosci. 2020;13:19 pubmed 出版商
Huang S, Wu L, Lee M, Chang C, Cheng W, Fang Y, et al. A robust TDP-43 knock-in mouse model of ALS. Acta Neuropathol Commun. 2020;8:3 pubmed 出版商
Zhao L, Ke H, Xu H, Wang G, Zhang H, Zou L, et al. TDP-43 facilitates milk lipid secretion by post-transcriptional regulation of Btn1a1 and Xdh. Nat Commun. 2020;11:341 pubmed 出版商
Braak H, Del Tredici K. From the Entorhinal Region via the Prosubiculum to the Dentate Fascia: Alzheimer Disease-Related Neurofibrillary Changes in the Temporal Allocortex. J Neuropathol Exp Neurol. 2020;79:163-175 pubmed 出版商
Sweeny E, Tariq A, Gurpinar E, Go M, Sochor M, Kan Z, et al. Structural and mechanistic insights into Hsp104 function revealed by synchrotron X-ray footprinting. J Biol Chem. 2020;295:1517-1538 pubmed 出版商
Nguyen T, Kabotyanski E, Reineke L, Shao J, Xiong F, Lee J, et al. The SINEB1 element in the long non-coding RNA Malat1 is necessary for TDP-43 proteostasis. Nucleic Acids Res. 2020;48:2621-2642 pubmed 出版商
Zhou Q, Mareljic N, Michaelsen M, Parhizkar S, Heindl S, Nuscher B, et al. Active poly-GA vaccination prevents microglia activation and motor deficits in a C9orf72 mouse model. EMBO Mol Med. 2020;12:e10919 pubmed 出版商
Isobe M, Toya H, Mito M, Chiba T, Asahara H, Hirose T, et al. Forced isoform switching of Neat1_1 to Neat1_2 leads to the loss of Neat1_1 and the hyperformation of paraspeckles but does not affect the development and growth of mice. RNA. 2020;26:251-264 pubmed 出版商
Robinson A, Chew Graham S, Davidson Y, Horan M, Roncaroli F, Minshull J, et al. A Comparative Study of Pathological Outcomes in The University of Manchester Longitudinal Study of Cognition in Normal Healthy Old Age and Brains for Dementia Research Cohorts. J Alzheimers Dis. 2020;73:619-632 pubmed 出版商
Hans F, Glasebach H, Kahle P. Multiple distinct pathways lead to hyperubiquitylated insoluble TDP-43 protein independent of its translocation into stress granules. J Biol Chem. 2020;295:673-689 pubmed 出版商
Zhao C, Devlin A, Chouhan A, Selvaraj B, Stavrou M, Burr K, et al. Mutant C9orf72 human iPSC-derived astrocytes cause non-cell autonomous motor neuron pathophysiology. Glia. 2019;: pubmed 出版商
Thierry M, Boluda S, Delatour B, Marty S, Seilhean D, Potier M, et al. Human subiculo-fornico-mamillary system in Alzheimer's disease: Tau seeding by the pillar of the fornix. Acta Neuropathol. 2019;: pubmed 出版商
Klingstedt T, Ghetti B, Holton J, Ling H, Nilsson K, Goedert M. Luminescent conjugated oligothiophenes distinguish between α-synuclein assemblies of Parkinson's disease and multiple system atrophy. Acta Neuropathol Commun. 2019;7:193 pubmed 出版商
Maurel C, Chami A, Thepault R, Marouillat S, Blasco H, Corcia P, et al. A role for SUMOylation in the Formation and Cellular Localization of TDP-43 Aggregates in Amyotrophic Lateral Sclerosis. Mol Neurobiol. 2019;: pubmed 出版商
Quadri Z, Johnson N, Zamudio F, Miller A, Peters M, Smeltzer S, et al. Overexpression of human wtTDP-43 causes impairment in hippocampal plasticity and behavioral deficits in CAMKII-tTa transgenic mouse model. Mol Cell Neurosci. 2019;102:103418 pubmed 出版商
Chadchankar J, Korboukh V, Conway L, Wobst H, Walker C, Doig P, et al. Inactive USP14 and inactive UCHL5 cause accumulation of distinct ubiquitinated proteins in mammalian cells. PLoS ONE. 2019;14:e0225145 pubmed 出版商
Couly S, Khalil B, Viguier V, Roussel J, Maurice T, Liévens J. Sigma-1 receptor is a key genetic modulator in amyotrophic lateral sclerosis. Hum Mol Genet. 2019;: pubmed 出版商
Kawaguchi T, Rollins M, Moinpour M, MORERA A, Ebmeier C, Old W, et al. Changes to the TDP-43 and FUS Interactomes Induced by DNA Damage. J Proteome Res. 2019;: pubmed 出版商
Lee S, Jeon Y, Cha S, Kim S, Kwon Y, Jo M, et al. PTK2/FAK regulates UPS impairment via SQSTM1/p62 phosphorylation in TARDBP/TDP-43 proteinopathies. Autophagy. 2019;:1-17 pubmed 出版商
Garces M, Guijarro M, Vargas A, Badiola J, Monzon M. Neuroglial patterns are shared by cerebella from prion and prion-like disorder affected patients. Mech Ageing Dev. 2019;184:111176 pubmed 出版商
Tam O, Rozhkov N, Shaw R, Kim D, Hubbard I, Fennessey S, et al. Postmortem Cortex Samples Identify Distinct Molecular Subtypes of ALS: Retrotransposon Activation, Oxidative Stress, and Activated Glia. Cell Rep. 2019;29:1164-1177.e5 pubmed 出版商
Bizarro J, Bhardwaj A, Smith S, Meier U. Nopp140-mediated concentration of telomerase in Cajal bodies regulates telomere length. Mol Biol Cell. 2019;30:3136-3150 pubmed 出版商
MORERA A, Ahmed N, Schwartz J. TDP-43 regulates transcription at protein-coding genes and Alu retrotransposons. Biochim Biophys Acta Gene Regul Mech. 2019;1862:194434 pubmed 出版商
Schmidt H, Barreau A, Rohatgi R. Phase separation-deficient TDP43 remains functional in splicing. Nat Commun. 2019;10:4890 pubmed 出版商
Williamson M, Finelli M, Sleigh J, Reddington A, Gordon D, Talbot K, et al. Neuronal over-expression of Oxr1 is protective against ALS-associated mutant TDP-43 mislocalisation in motor neurons and neuromuscular defects in vivo. Hum Mol Genet. 2019;28:3584-3599 pubmed 出版商
Zhu J, Wang N, Li X, Zheng X, Zhao J, Xia H, et al. Suppression of Progranulin Expression Leads to Formation of Intranuclear TDP-43 Inclusions In Vitro: A Cell Model of Frontotemporal Lobar Degeneration. J Neuropathol Exp Neurol. 2019;78:1124-1129 pubmed 出版商
Brettle M, Stefen H, Djordjevic A, Fok S, Chan J, Van Hummel A, et al. Developmental Expression of Mutant PFN1 in Motor Neurons Impacts Neuronal Growth and Motor Performance of Young and Adult Mice. Front Mol Neurosci. 2019;12:231 pubmed 出版商
Chen H, Topp S, Hui H, Zacco E, Katarya M, McLoughlin C, et al. RRM adjacent TARDBP mutations disrupt RNA binding and enhance TDP-43 proteinopathy. Brain. 2019;142:3753-3770 pubmed 出版商
Mori S, Honda H, Ishii T, Yoshimura M, Sasagasako N, Suzuki S, et al. Expanded polyglutamine impairs normal nuclear distribution of fused in sarcoma and poly (rC)-binding protein 1 in Huntington's disease. Neuropathology. 2019;39:358-367 pubmed 出版商
Chen J, Nathaniel D, Raghavan P, Nelson M, Tian R, Tse E, et al. Compromised function of the ESCRT pathway promotes endolysosomal escape of tau seeds and propagation of tau aggregation. J Biol Chem. 2019;294:18952-18966 pubmed 出版商
Liao Y, Fernandopulle M, Wang G, Choi H, Hao L, Drerup C, et al. RNA Granules Hitchhike on Lysosomes for Long-Distance Transport, Using Annexin A11 as a Molecular Tether. Cell. 2019;179:147-164.e20 pubmed 出版商
Yamashita S, Kimura E, Zhang Z, Tawara N, Hara K, Yoshimura A, et al. Muscle pathology of hereditary motor and sensory neuropathy with proximal dominant involvement with TFG mutation. Muscle Nerve. 2019;: pubmed 出版商
Tariq A, Lin J, Jackrel M, Hesketh C, Carman P, Mack K, et al. Mining Disaggregase Sequence Space to Safely Counter TDP-43, FUS, and α-Synuclein Proteotoxicity. Cell Rep. 2019;28:2080-2095.e6 pubmed 出版商
Heyburn L, Abutarboush R, Goodrich S, Urioste R, Batuure A, Statz J, et al. Repeated Low-Level Blast Overpressure Leads to Endovascular Disruption and Alterations in TDP-43 and Piezo2 in a Rat Model of Blast TBI. Front Neurol. 2019;10:766 pubmed 出版商
Yamashita S, Matsuo Y, Tawara N, Hara K, Yamamoto M, Nishikami T, et al. CYLD dysregulation in pathogenesis of sporadic inclusion body myositis. Sci Rep. 2019;9:11606 pubmed 出版商
Fischer N, Preuße C, Radke J, Pehl D, Allenbach Y, Schneider U, et al. Sequestosome-1 (p62) expression reveals chaperone-assisted selective autophagy in immune-mediated necrotizing myopathies. Brain Pathol. 2019;: pubmed 出版商
Gu J, Hu W, Tan X, Qu S, Chu D, Gong C, et al. Elevation of casein kinase 1ε associated with TDP-43 and tau pathologies in Alzheimer's disease. Brain Pathol. 2019;: pubmed 出版商
Donde A, Sun M, Ling J, Braunstein K, Pang B, Wen X, et al. Splicing repression is a major function of TDP-43 in motor neurons. Acta Neuropathol. 2019;: pubmed 出版商
Sugai A, Kato T, Koyama A, Koike Y, Konno T, Ishihara T, et al. Non-genetically modified models exhibit TARDBP mRNA increase due to perturbed TDP-43 autoregulation. Neurobiol Dis. 2019;130:104534 pubmed 出版商
Shi Y, Hung S, Rocha G, Lin S, Linares G, Staats K, et al. Identification and therapeutic rescue of autophagosome and glutamate receptor defects in C9ORF72 and sporadic ALS neurons. JCI Insight. 2019;5: pubmed 出版商
Kim S, Chung A, Na J, Lee S, Jeong S, Kim E, et al. Myelin degeneration induced by mutant superoxide dismutase 1 accumulation promotes amyotrophic lateral sclerosis. Glia. 2019;67:1910-1921 pubmed 出版商
Hicks D, Cross L, Williamson R, Rattray M. Endoplasmic Reticulum Stress Signalling Induces Casein Kinase 1-Dependent Formation of Cytosolic TDP-43 Inclusions in Motor Neuron-Like Cells. Neurochem Res. 2019;: pubmed 出版商
Hao Z, Liu L, Tao Z, Wang R, Ren H, Sun H, et al. Motor dysfunction and neurodegeneration in a C9orf72 mouse line expressing poly-PR. Nat Commun. 2019;10:2906 pubmed 出版商
Josephs K, Zhang Y, Baker M, Rademakers R, Petrucelli L, Dickson D. C-terminal and full length TDP-43 specie differ according to FTLD-TDP lesion type but not genetic mutation. Acta Neuropathol Commun. 2019;7:100 pubmed 出版商
Donde A, Sun M, Jeong Y, Wen X, Ling J, Lin S, et al. Upregulation of ATG7 attenuates motor neuron dysfunction associated with depletion of TARDBP/TDP-43. Autophagy. 2019;:1-11 pubmed 出版商
Larocca T, Mariani A, Watkins L, Link C. TDP-43 knockdown causes innate immune activation via protein kinase R in astrocytes. Neurobiol Dis. 2019;:104514 pubmed 出版商
Kattuah W, Rogelj B, King A, Shaw C, Hortobagyi T, Troakes C. Heterogeneous Nuclear Ribonucleoprotein E2 (hnRNP E2) Is a Component of TDP-43 Aggregates Specifically in the A and C Pathological Subtypes of Frontotemporal Lobar Degeneration. Front Neurosci. 2019;13:551 pubmed 出版商
Koza P, Beroun A, Konopka A, Gorkiewicz T, Bijoch L, Torres J, et al. Neuronal TDP-43 depletion affects activity-dependent plasticity. Neurobiol Dis. 2019;130:104499 pubmed 出版商
Nicoll J, Buckland G, Harrison C, Page A, Harris S, Love S, et al. Persistent neuropathological effects 14 years following amyloid-β immunization in Alzheimer's disease. Brain. 2019;: pubmed 出版商
Riku Y, Duyckaerts C, Boluda S, Plu I, Le Ber I, Millecamps S, et al. Increased prevalence of granulovacuolar degeneration in C9orf72 mutation. Acta Neuropathol. 2019;: pubmed 出版商
Takahashi Y, Uchino A, Shioya A, Sano T, Matsumoto C, Numata Uematsu Y, et al. Altered immunoreactivity of ErbB4, a causative gene product for ALS19, in the spinal cord of patients with sporadic ALS. Neuropathology. 2019;39:268-278 pubmed 出版商
Goodman L, Prudencio M, Kramer N, Martinez Ramirez L, Srinivasan A, Lan M, et al. Toxic expanded GGGGCC repeat transcription is mediated by the PAF1 complex in C9orf72-associated FTD. Nat Neurosci. 2019;: pubmed 出版商
Wang P, Deng J, Dong J, Liu J, Bigio E, Mesulam M, et al. TDP-43 induces mitochondrial damage and activates the mitochondrial unfolded protein response. PLoS Genet. 2019;15:e1007947 pubmed 出版商
Gregory A, Lotia M, Jeong S, Fox R, Zhen D, Sanford L, et al. Autosomal dominant mitochondrial membrane protein-associated neurodegeneration (MPAN). Mol Genet Genomic Med. 2019;:e736 pubmed 出版商
Modic M, Grosch M, Rot G, Schirge S, Lepko T, Yamazaki T, et al. Cross-Regulation between TDP-43 and Paraspeckles Promotes Pluripotency-Differentiation Transition. Mol Cell. 2019;74:951-965.e13 pubmed 出版商
Liu E, Russ J, Cali C, Phan J, Amlie Wolf A, Lee E. Loss of Nuclear TDP-43 Is Associated with Decondensation of LINE Retrotransposons. Cell Rep. 2019;27:1409-1421.e6 pubmed 出版商
Naasan G, Shany Ur T, Sidhu M, Barton C, Ketelle R, Shdo S, et al. Corticobasal syndrome with visual hallucinations and probable REM-sleep behavior disorder: an autopsied case report of a patient with CBD and LBD pathology. Neurocase. 2019;25:26-33 pubmed 出版商
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产品信息
目录号 :
10782-2-AP
AntigenName :
TDP-43
Package :
150UL
价格 :
299美元
Exsists20ul :
20ul trial size available
FullName :
焦油DNA结合蛋白
免疫原 :
重组蛋白
物种 :
c. elegans, chicken, dog, drosophila, fly, hamster, horse, human, monkey, mouse, pig, rat, worm, yeast, zebrafish
宿主 :
IsConjugated :
未共轭
AntigenSpecies :
人类
应用 :
免疫印迹, RIP, 免疫沉淀, 免疫组化, IF, IEM, FC, CoIP, chIP, 酶联免疫吸附测定
Clonlity :
多克隆
抗体亚型 :
IgG
同义词 :
ALS10, 焦油DNA结合蛋白, 焦油DNA结合蛋白43, TARDBP, TAR DNA结合蛋白43, TDP43
PrimaryOrSecondary :
Primary
抗体缓冲液 :
PBS含0.1%叠氮化钠和50% 甘油pH值7.3
GenBank登录号 :
BC001487
类别 :
Binding Proteins;Cytoskeleton/Scaffold Proteins;Disease Related;Metabolism;Neurology;
PurifyMethod :
抗原亲和纯化
NewAb :
False
IsSellable :
True
Feature :
siRNA
AppTiter :
FC 1:0;IF 1:100;免疫组化1:2000;免疫印迹1:5000;
公司信息
武汉三鹰
武汉市洪山区关山二路关东科技园7-4#,402室
Service@ptglab.com
http://www.ptgcn.com
4006 900 926, 027-87531629 / 027-87531627
公司总部: 美国
Proteintech Group致力于开发针对所有人类蛋白的抗体,我们将这项计划命名为人类抗体组计划。Proteintech Group在科研领域享有良好声誉, 迄今已生产出针对10,000种不同人类蛋白的10,000种抗体。同时,Proteintech Group也提供多种客户订单服务:克隆,表达,多肽合成,多抗及单抗生产,以满足您的不同需求。

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我们承诺为您提供高品质的抗体及相关产品,让您不再担忧试剂的品质,让您能够倾注您全部的创造力,才华和精力于研究当中。我们坚信只有您成功了,我们才会成功。