产品简要
公司名称 :
武汉三鹰
产品类型 :
抗体
产品名称 :
alpha突触核蛋白
目录 :
10842-1-AP
规格 :
150UL
价格 :
299美元
克隆性 :
多克隆
宿主 :
domestic rabbit
共轭标签 :
未共轭
反应物种 :
人类
应用 :
免疫印迹, 酶联免疫吸附测定, 免疫组化, 免疫细胞化学
更多信息或购买 :
文章摘录数: 19
出版应用/物种/样本/稀释参考文献
  • 免疫印迹; 人类; 1:100; 图 1f
Kakimoto Y, Sasaki A, Niioka M, Kawabe N, Osawa M. Myocardial cathepsin D is downregulated in sudden cardiac death. PLoS ONE. 2020;15:e0230375 pubmed 出版商
Mao K, Chen J, Yu H, Li H, Ren Y, Wu X, et al. Poly (ADP-ribose) polymerase 1 inhibition prevents neurodegeneration and promotes α-synuclein degradation via transcription factor EB-dependent autophagy in mutant α-synucleinA53T model of Parkinson's disease. Aging Cell. 2020;19:e13163 pubmed 出版商
Chadchankar J, Korboukh V, Conway L, Wobst H, Walker C, Doig P, et al. Inactive USP14 and inactive UCHL5 cause accumulation of distinct ubiquitinated proteins in mammalian cells. PLoS ONE. 2019;14:e0225145 pubmed 出版商
Chiu C, Yeh T, Chen R, Chen H, Huang Y, Weng Y, et al. Upregulated Expression of MicroRNA-204-5p Leads to the Death of Dopaminergic Cells by Targeting DYRK1A-Mediated Apoptotic Signaling Cascade. Front Cell Neurosci. 2019;13:399 pubmed 出版商
So L, Munger S, Miller J. Social context-dependent singing alters molecular markers of dopaminergic and glutamatergic signaling in finch basal ganglia Area X. Behav Brain Res. 2019;360:103-112 pubmed 出版商
Zhou P, Homberg J, Fang Q, Wang J, Li W, Meng X, et al. Histamine-4 receptor antagonist JNJ7777120 inhibits pro-inflammatory microglia and prevents the progression of Parkinson-like pathology and behaviour in a rat model. Brain Behav Immun. 2019;76:61-73 pubmed 出版商
Chiu C, Lu C, Weng Y, Chen Y, Huang Y, Chen R, et al. PARK14 (D331Y) PLA2G6 Causes Early-Onset Degeneration of Substantia Nigra Dopaminergic Neurons by Inducing Mitochondrial Dysfunction, ER Stress, Mitophagy Impairment and Transcriptional Dysregulation in a Knockin Mouse Model. Mol Neurobiol. 2019;56:3835-3853 pubmed 出版商
Remor A, da Silva R, de Matos F, Glaser V, de Paula Martins R, Ghisoni K, et al. Chronic Metabolic Derangement-Induced Cognitive Deficits and Neurotoxicity Are Associated with REST Inactivation. Mol Neurobiol. 2019;56:1539-1557 pubmed 出版商
Su J, Wang H, Yang Y, Wang J, Li H, Huang D, et al. RESP18 deficiency has protective effects in dopaminergic neurons in an MPTP mouse model of Parkinson's disease. Neurochem Int. 2018;118:195-204 pubmed 出版商
Chen J, Ren Y, Gui C, Zhao M, Wu X, Mao K, et al. Phosphorylation of Parkin at serine 131 by p38 MAPK promotes mitochondrial dysfunction and neuronal death in mutant A53T α-synuclein model of Parkinson's disease. Cell Death Dis. 2018;9:700 pubmed 出版商
Koga S, Lin W, Walton R, Ross O, Dickson D. TDP-43 pathology in multiple system atrophy: colocalization of TDP-43 and α-synuclein in glial cytoplasmic inclusions. Neuropathol Appl Neurobiol. 2018;44:707-721 pubmed 出版商
Tayebi N, Parisiadou L, Berhe B, Gonzalez A, Serra Vinardell J, Tamargo R, et al. Glucocerebrosidase haploinsufficiency in A53T ?-synuclein mice impacts disease onset and course. Mol Genet Metab. 2017;122:198-208 pubmed 出版商
Huang C, Zhu L, Li H, Shi F, Wang G, Wei Y, et al. Adulthood Exposure to Lipopolysaccharide Exacerbates the Neurotoxic and Inflammatory Effects of Rotenone in the Substantia Nigra. Front Mol Neurosci. 2017;10:131 pubmed 出版商
Duan J, Ying Z, Su Y, Lin F, Deng Y. ?-Synuclein binds to cytoplasmic vesicles in U251 glioblastoma cells. Neurosci Lett. 2017;642:148-152 pubmed 出版商
Rodríguez Nogales C, Garbayo E, Martinez Valbuena I, Sebastian V, Luquin M, Blanco Prieto M. Development and characterization of polo-like kinase 2 loaded nanoparticles-A novel strategy for (serine-129) phosphorylation of alpha-synuclein. Int J Pharm. 2016;514:142-149 pubmed 出版商
Marques F, Tenney J, Durán I, Martin J, Nevarez L, Pogue R, et al. Altered mRNA Splicing, Chondrocyte Gene Expression and Abnormal Skeletal Development due to SF3B4 Mutations in Rodriguez Acrofacial Dysostosis. PLoS Genet. 2016;12:e1006307 pubmed 出版商
Yang W, Wang G, Wang C, Guo X, Yin P, Gao J, et al. Mutant alpha-synuclein causes age-dependent neuropathology in monkey brain. J Neurosci. 2015;35:8345-58 pubmed 出版商
Xiang W, Menges S, Schlachetzki J, Meixner H, Hoffmann A, Schlötzer Schrehardt U, et al. Posttranslational modification and mutation of histidine 50 trigger alpha synuclein aggregation and toxicity. Mol Neurodegener. 2015;10:8 pubmed 出版商
Xiong J, Zhang X, Huang J, Chen C, Chen Z, Liu L, et al. Fenpropathrin, a Widely Used Pesticide, Causes Dopaminergic Degeneration. Mol Neurobiol. 2016;53:995-1008 pubmed 出版商
图像
图像 1 :
武汉三鹰 10842-1-AP 图像 1
The alpha-synuclein antibody from Proteintech is a rabbit polyclonal antibody to a recombinant protein of human alpha-synuclein. This antibody recognizes human,mouse,rat antigen. The alpha-synuclein antibody has been validated for the following applications: IF, IHC, WB, ELISA analysis.
产品信息
目录号 :
10842-1-AP
AntigenName :
alpha突触核蛋白
Package :
150UL
价格 :
299美元
Exsists20ul :
20ul trial size available
FullName :
synuclein, alpha (non A4 component of amyloid precursor)
免疫原 :
重组蛋白
物种 :
human, mouse, rat, zebra finches
宿主 :
IsConjugated :
未共轭
AntigenSpecies :
人类
应用 :
免疫印迹, 免疫组化, IF, 酶联免疫吸附测定
Clonlity :
多克隆
抗体亚型 :
IgG
同义词 :
alpha突触核蛋白, NACP, PARK1, PARK4, PD1, SNCA
PrimaryOrSecondary :
Primary
抗体缓冲液 :
PBS含0.1%叠氮化钠和50% 甘油pH值7.3
GenBank登录号 :
BC013293
类别 :
Binding Proteins;Cytoskeleton/Scaffold Proteins;Disease Related;Membrane Proteins;Neurology;Transport/Trafficking;
PurifyMethod :
抗原亲和纯化
NewAb :
False
IsSellable :
True
AppTiter :
IF 1:25;免疫组化1:200;免疫印迹1:800;
更多信息或购买 :
公司信息
武汉三鹰
武汉市洪山区关山二路关东科技园7-4#,402室
Service@ptglab.com
http://www.ptgcn.com
4006 900 926, 027-87531629 / 027-87531627
公司总部: 美国
Proteintech Group致力于开发针对所有人类蛋白的抗体,我们将这项计划命名为人类抗体组计划。Proteintech Group在科研领域享有良好声誉, 迄今已生产出针对10,000种不同人类蛋白的10,000种抗体。同时,Proteintech Group也提供多种客户订单服务:克隆,表达,多肽合成,多抗及单抗生产,以满足您的不同需求。

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