产品简要
公司名称 :
武汉三鹰
产品类型 :
抗体
产品名称 :
IRF3
目录 :
11312-1-AP
规格 :
150UL
价格 :
299美元
克隆性 :
多克隆
宿主 :
domestic rabbit
共轭标签 :
未共轭
反应物种 :
人类, 小鼠
应用 :
免疫印迹, 酶联免疫吸附测定, 免疫组化, 免疫细胞化学, 免疫沉淀, 流式细胞仪
更多信息或购买 :
文章摘录数: 39
出版应用/物种/样本/稀释参考文献
  • 免疫印迹; 小鼠; 1:2000; 图 3a, 3c, 4a
Liu Z, Wu C, Pan Y, Liu H, Wang X, Yang Y, et al. NDR2 promotes the antiviral immune response via facilitating TRIM25-mediated RIG-I activation in macrophages. Sci Adv. 2019;5:eaav0163 pubmed 出版商
  • 免疫印迹; 小鼠; 1:3000; 图 s4a
Liu Z, Qin Q, Wu C, Li H, Shou J, Yang Y, et al. Downregulated NDR1 protein kinase inhibits innate immune response by initiating an miR146a-STAT1 feedback loop. Nat Commun. 2018;9:2789 pubmed 出版商
  • 免疫印迹; 小鼠; 图 2A
  • 免疫印迹; 人类; 图 5A
Bakshi S, Taylor J, Strickson S, McCartney T, Cohen P. Identification of TBK1 complexes required for the phosphorylation of IRF3 and the production of interferon ?. Biochem J. 2017;474:1163-1174 pubmed 出版商
  • 免疫印迹; 人类; 图 7c
Zhang X, Zheng Z, Liu X, Shu B, Mao P, Bai B, et al. Tick-borne encephalitis virus induces chemokine RANTES expression via activation of IRF-3 pathway. J Neuroinflammation. 2016;13:209 pubmed 出版商
Zhao Y, Hao C, Bao L, Wang D, Li Y, Qu Y, et al. Silica particles disorganize the polarization of pulmonary macrophages in mice. Ecotoxicol Environ Saf. 2020;193:110364 pubmed 出版商
Xue M, Liang H, Ji X, Liu Y, Ge Y, Hou L, et al. Fucoidan prevent murine autoimmune diabetes via suppression TLR4-signaling pathways, regulation DC/Treg induced immune tolerance and improving gut microecology. Nutr Metab (Lond). 2019;16:87 pubmed 出版商
Hu S, Sun H, Yin L, Li J, Mei S, Xu F, et al. PKR-dependent cytosolic cGAS foci are necessary for intracellular DNA sensing. Sci Signal. 2019;12: pubmed 出版商
Wan W, Wang L, Chen X, Zhu S, Shang W, Xiao G, et al. A Subcellular Quantitative Proteomic Analysis of Herpes Simplex Virus Type 1-Infected HEK 293T Cells. Molecules. 2019;24: pubmed 出版商
Lou Y, Han M, Liu H, Niu Y, Liang Y, Guo J, et al. Essential roles of S100A10 in Toll-like receptor signaling and immunity to infection. Cell Mol Immunol. 2019;: pubmed 出版商
Xu G, Xia Z, Deng F, Liu L, Wang Q, Yu Y, et al. Inducible LGALS3BP/90K activates antiviral innate immune responses by targeting TRAF6 and TRAF3 complex. PLoS Pathog. 2019;15:e1008002 pubmed 出版商
Zhu W, Li J, Zhang R, Cai Y, Wang C, Qi S, et al. TRAF3IP3 mediates the recruitment of TRAF3 to MAVS for antiviral innate immunity. EMBO J. 2019;:e102075 pubmed 出版商
Zierhut C, Yamaguchi N, Paredes M, Luo J, Carroll T, Funabiki H. The Cytoplasmic DNA Sensor cGAS Promotes Mitotic Cell Death. Cell. 2019;178:302-315.e23 pubmed 出版商
Sanjo H, Nakayama J, Yoshizawa T, Fehling H, Akira S, Taki S. Cutting Edge: TAK1 Safeguards Macrophages against Proinflammatory Cell Death. J Immunol. 2019;203:783-788 pubmed 出版商
Xia Z, Xu G, Nie L, Liu L, Peng N, He Q, et al. NAC1 Potentiates Cellular Antiviral Signaling by Bridging MAVS and TBK1. J Immunol. 2019;: pubmed 出版商
Chavez Valdez R, Mottahedin A, Stridh L, Yellowhair T, Jantzie L, Northington F, et al. Evidence for Sexual Dimorphism in the Response to TLR3 Activation in the Developing Neonatal Mouse Brain: A Pilot Study. Front Physiol. 2019;10:306 pubmed 出版商
Guan X, Zhang M, Fu M, Luo S, Hu Q. Herpes Simplex Virus Type 2 Immediate Early Protein ICP27 Inhibits IFN-β Production in Mucosal Epithelial Cells by Antagonizing IRF3 Activation. Front Immunol. 2019;10:290 pubmed 出版商
Su Z, Dziedzic S, Hu D, Barrett V, Broekema N, Li W, et al. ABIN-1 heterozygosity sensitizes to innate immune response in both RIPK1-dependent and RIPK1-independent manner. Cell Death Differ. 2019;26:1077-1088 pubmed 出版商
Yang Q, Tang J, Pei R, Gao X, Guo J, Xu C, et al. Host HDAC4 regulates the antiviral response by inhibiting the phosphorylation of IRF3. J Mol Cell Biol. 2019;11:158-169 pubmed 出版商
Wang X, Wu J, Wu Y, Chen H, Zhang S, Li J, et al. Inhibition of cGAS-STING-TBK1 signaling pathway by DP96R of ASFV China 2018/1. Biochem Biophys Res Commun. 2018;506:437-443 pubmed 出版商
Gao X, Chen D, Hu X, Zhou Y, Wang Y, Wu C, et al. PLA1A Participates in the Antiviral Innate Immune Response by Facilitating the Recruitment of TANK-Binding Kinase 1 to Mitochondria. J Innate Immun. 2018;10:315-327 pubmed 出版商
Cai J, Chen H, Peng S, Meng J, Wang Y, Zhou Y, et al. USP7-TRIM27 axis negatively modulates antiviral type I IFN signaling. FASEB J. 2018;32:5238-5249 pubmed 出版商
Zhou P, Ding X, Wan X, Liu L, Yuan X, Zhang W, et al. MLL5 suppresses antiviral innate immune response by facilitating STUB1-mediated RIG-I degradation. Nat Commun. 2018;9:1243 pubmed 出版商
Xie J, Li Y, Shen X, Goh G, Zhu Y, Cui J, et al. Dampened STING-Dependent Interferon Activation in Bats. Cell Host Microbe. 2018;23:297-301.e4 pubmed 出版商
Cao Y, Wang H, Yang L, Zhang Z, Li C, Yuan X, et al. PTEN-L promotes type I interferon responses and antiviral immunity. Cell Mol Immunol. 2018;15:48-57 pubmed 出版商
Lian S, Guo J, Wang L, Li W, Wang J, Ji H, et al. Impact of prenatal cold stress on placental physiology, inflammatory response, and apoptosis in rats. Oncotarget. 2017;8:115304-115314 pubmed 出版商
Yi C, Zhao Z, Wang S, Sun X, Zhang D, Sun X, et al. Influenza A Virus PA Antagonizes Interferon-? by Interacting with Interferon Regulatory Factor 3. Front Immunol. 2017;8:1051 pubmed 出版商
Zhao M, Wan B, Li H, He J, Chen X, Wang L, et al. Porcine 2', 5'-oligoadenylate synthetase 2 inhibits porcine reproductive and respiratory syndrome virus replication in vitro. Microb Pathog. 2017;111:14-21 pubmed 出版商
Zhang H, Ye H, Liu S, Deng C, Li X, Shi P, et al. West Nile Virus NS1 Antagonizes Interferon Beta Production by Targeting RIG-I and MDA5. J Virol. 2017;91: pubmed 出版商
Jiang Z, Song F, Li Y, Xue D, Deng G, Li M, et al. Capsular Polysaccharide is a Main Component of Mycoplasma ovipneumoniae in the Pathogen-Induced Toll-Like Receptor-Mediated Inflammatory Responses in Sheep Airway Epithelial Cells. Mediators Inflamm. 2017;2017:9891673 pubmed 出版商
Nie Y, Ran Y, Zhang H, Huang Z, Pan Z, Wang S, et al. GPATCH3 negatively regulates RLR-mediated innate antiviral responses by disrupting the assembly of VISA signalosome. PLoS Pathog. 2017;13:e1006328 pubmed 出版商
Song S, Peng P, Tang Z, Zhao J, Wu W, Li H, et al. Decreased expression of STING predicts poor prognosis in patients with gastric cancer. Sci Rep. 2017;7:39858 pubmed 出版商
Lang X, Tang T, Jin T, Ding C, Zhou R, Jiang W. TRIM65-catalized ubiquitination is essential for MDA5-mediated antiviral innate immunity. J Exp Med. 2017;214:459-473 pubmed 出版商
Liu C, Yue R, Yang Y, Cui Y, Yang L, Zhao D, et al. AIM2 inhibits autophagy and IFN-? production during M. bovis infection. Oncotarget. 2016;7:46972-46987 pubmed 出版商
Zeng L, Gao Y, Ge X, Zhang Q, Peng C, Yang X, et al. Bat Severe Acute Respiratory Syndrome-Like Coronavirus WIV1 Encodes an Extra Accessory Protein, ORFX, Involved in Modulation of the Host Immune Response. J Virol. 2016;90:6573-6582 pubmed 出版商
Li S, Zhu M, Pan R, Fang T, Cao Y, Chen S, et al. The tumor suppressor PTEN has a critical role in antiviral innate immunity. Nat Immunol. 2016;17:241-9 pubmed 出版商
Li L, Qin J, Guo S, Zhang P, Gong J, Zhang X, et al. Attenuation of cerebral ischemic injury in interferon regulatory factor 3-deficient rat. J Neurochem. 2016;136:871-883 pubmed 出版商
Zhu M, Fang T, Li S, Meng K, Guo D. Bipartite Nuclear Localization Signal Controls Nuclear Import and DNA-Binding Activity of IFN Regulatory Factor 3. J Immunol. 2015;195:289-97 pubmed 出版商
Li M, Guo S, Zhang P, Gong J, Zheng A, Zhang Y, et al. Vinexin-β deficiency protects against cerebral ischaemia/reperfusion injury by inhibiting neuronal apoptosis. J Neurochem. 2015;134:211-21 pubmed 出版商
Zhang M, Liu Y, Wang P, Guan X, He S, Luo S, et al. HSV-2 immediate-early protein US1 inhibits IFN-β production by suppressing association of IRF-3 with IFN-β promoter. J Immunol. 2015;194:3102-15 pubmed 出版商
图像
图像 1 :
武汉三鹰 11312-1-AP 图像 1
The IRF3 antibody from Proteintech is a rabbit polyclonal antibody to a recombinant protein of human IRF3. This antibody recognizes human, mouse, rat antigen. The IRF3 antibody has been validated for the following applications: FC, IF, IHC, IP, WB, ELISA analysis.
产品信息
目录号 :
11312-1-AP
AntigenName :
IRF3
Package :
150UL
价格 :
299美元
Exsists20ul :
20ul trial size available
FullName :
干扰素调节因子3
免疫原 :
重组蛋白
物种 :
人类, 小鼠, 猪, 大鼠, 羊, 猪
宿主 :
IsConjugated :
未共轭
AntigenSpecies :
人类
应用 :
免疫印迹, 免疫沉淀, 免疫组化, IF, FC, 酶联免疫吸附测定
Clonlity :
多克隆
抗体亚型 :
IgG
同义词 :
干扰素调节因子3, IRF 3, IRF3
PrimaryOrSecondary :
Primary
抗体缓冲液 :
PBS含0.1%叠氮化钠和50% 甘油pH值7.3
GenBank登录号 :
BC009395
类别 :
Binding Proteins;Cytoskeleton/Scaffold Proteins;Immunology;Metabolism;Oncogene(s) and Tumor Suppressor(s);Signal transduction;
PurifyMethod :
抗原亲和纯化
NewAb :
False
IsSellable :
True
Feature :
siRNA
AppTiter :
FC 1:0;IF 1:25;免疫组化1:50;免疫沉淀1:1000;免疫印迹1:5000;
更多信息或购买 :
公司信息
武汉三鹰
武汉市洪山区关山二路关东科技园7-4#,402室
Service@ptglab.com
http://www.ptgcn.com
4006 900 926, 027-87531629 / 027-87531627
公司总部: 美国
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