产品简要
公司名称 :
武汉三鹰
产品类型 :
抗体
产品名称 :
KRAS
目录 :
12063-1-AP
规格 :
150UL
价格 :
299美元
克隆性 :
多克隆
宿主 :
domestic rabbit
共轭标签 :
未共轭
反应物种 :
人类, 小鼠
应用 :
免疫印迹, 酶联免疫吸附测定, 免疫组化, 免疫细胞化学, 免疫沉淀, 流式细胞仪
更多信息或购买 :
文章摘录数: 42
出版应用/物种/样本/稀释参考文献
  • 免疫印迹; 小鼠; 图 5c
Adams C, Htwe H, Marsh T, Wang A, Montoya M, Subbaraj L, et al. Transcriptional control of subtype switching ensures adaptation and growth of pancreatic cancer. elife. 2019;8: pubmed 出版商
Xiong X, Rao G, Roy R, Zhang Y, Means N, Dey A, et al. Ubiquitin-binding associated protein 2 regulates KRAS activation and macropinocytosis in pancreatic cancer. FASEB J. 2020;: pubmed 出版商
Kumazaki M, Shimomura I, Kiyono T, Ochiya T, Yamamoto Y. Cell-type specific tumorigenesis with Ras oncogenes in human lung epithelial cells. Biochem Biophys Res Commun. 2020;525:483-490 pubmed 出版商
Zhang X, Ma N, Yao W, Li S, Ren Z. RAD51 is a potential marker for prognosis and regulates cell proliferation in pancreatic cancer. Cancer Cell Int. 2019;19:356 pubmed 出版商
Sale M, Minihane E, Monks N, Gilley R, Richards F, Schifferli K, et al. Targeting melanoma's MCL1 bias unleashes the apoptotic potential of BRAF and ERK1/2 pathway inhibitors. Nat Commun. 2019;10:5167 pubmed 出版商
Che Y, Siprashvili Z, Kovalski J, Jiang T, Wozniak G, Elcavage L, et al. KRAS regulation by small non-coding RNAs and SNARE proteins. Nat Commun. 2019;10:5118 pubmed 出版商
Zhao H, Wu S, Li H, Duan Q, Zhang Z, Shen Q, et al. ROS/KRAS/AMPK Signaling Contributes to Gemcitabine-Induced Stem-like Cell Properties in Pancreatic Cancer. Mol Ther Oncolytics. 2019;14:299-312 pubmed 出版商
Chen S, Li D, Zhang H, Yu D, Chen R, Zhang B, et al. The development of a cell-based model for the assessment of carcinogenic potential upon long-term PM2.5 exposure. Environ Int. 2019;131:104943 pubmed 出版商
Huang L, Wang Y, Chen J, Wang Y, Zhao Y, Wang Y, et al. Long noncoding RNA PCAT1, a novel serum-based biomarker, enhances cell growth by sponging miR-326 in oesophageal squamous cell carcinoma. Cell Death Dis. 2019;10:513 pubmed 出版商
Zhang W, He P, Wang S, Adili A, Chen Z, Zhang C, et al. Characterization of Protein Profiling and mRNA Expression of LLC Exosomes. Protein J. 2019;: pubmed 出版商
Ida K, Miyamoto T, Higuchi S, Takeuchi H, Yamada S, Ono M, et al. Effectiveness of a genetic test panel designed for gynecological cancer: an exploratory study. Med Oncol. 2019;36:62 pubmed 出版商
Chen Y, Liu Z, Wang H, Tang Z, Liu Y, Liang Z, et al. VPS33B negatively modulated by nicotine functions as a tumor suppressor in colorectal cancer. Int J Cancer. 2019;: pubmed 出版商
Zhao Y, Zhong S, Zhang S, Bi J, Xiao Z, Wang S, et al. UBN2 promotes tumor progression via the Ras/MAPK pathway and predicts poor prognosis in colorectal cancer. Cancer Cell Int. 2019;19:126 pubmed 出版商
Chen Z, Yang D, Jiang X, Tian L, Sun J, Tian D, et al. Final-2 targeted glycolysis mediated apoptosis and autophagy in human lung adenocarcinoma cells but failed to inhibit xenograft in nude mice. Food Chem Toxicol. 2019;130:1-11 pubmed 出版商
Gao L, Hu Y, Tian Y, Fan Z, Wang K, Li H, et al. Lung cancer deficient in the tumor suppressor GATA4 is sensitive to TGFBR1 inhibition. Nat Commun. 2019;10:1665 pubmed 出版商
Chen Z, Tian D, Liao X, Zhang Y, Xiao J, Chen W, et al. Apigenin Combined With Gefitinib Blocks Autophagy Flux and Induces Apoptotic Cell Death Through Inhibition of HIF-1α, c-Myc, p-EGFR, and Glucose Metabolism in EGFR L858R+T790M-Mutated H1975 Cells. Front Pharmacol. 2019;10:260 pubmed 出版商
Xu H, Zhou S, Xia H, Yu H, Tang Q, Bi F. MEK nuclear localization promotes YAP stability via sequestering β-TrCP in KRAS mutant cancer cells. Cell Death Differ. 2019;: pubmed 出版商
Mo X, Tang C, Niu Q, Ma T, Du Y, Fu H. HTiP: High-Throughput Immunomodulator Phenotypic Screening Platform to Reveal IAP Antagonists as Anti-cancer Immune Enhancers. Cell Chem Biol. 2019;26:331-339.e3 pubmed 出版商
Dai X, Xia H, Zhou S, Tang Q, Bi F. Zoledronic acid enhances the efficacy of the MEK inhibitor trametinib in KRAS mutant cancers. Cancer Lett. 2018;442:202-212 pubmed 出版商
Gao P, Wang X, Jin Y, Hu W, Duan Y, Shi A, et al. Nogo-B receptor increases the resistance to tamoxifen in estrogen receptor-positive breast cancer cells. Breast Cancer Res. 2018;20:112 pubmed 出版商
Du Z, Song X, Yan F, Wang J, Zhao Y, Liu S. Genome-wide transcriptional analysis of BRD4-regulated genes and pathways in human glioma U251 cells. Int J Oncol. 2018;: pubmed 出版商
Akao Y, Kumazaki M, Shinohara H, Sugito N, Kuranaga Y, Tsujino T, et al. Impairment of K-Ras signaling networks and increased efficacy of epidermal growth factor receptor inhibitors by a novel synthetic miR-143. Cancer Sci. 2018;109:1455-1467 pubmed 出版商
Wu D, Zhao B, Qi X, Peng F, Fu H, Chi X, et al. Nogo-B receptor promotes epithelial-mesenchymal transition in non-small cell lung cancer cells through the Ras/ERK/Snail1 pathway. Cancer Lett. 2018;418:135-146 pubmed 出版商
Chen M, Lin M, Wang X. Overexpression of miR-19a inhibits colorectal cancer angiogenesis by suppressing KRAS expression. Oncol Rep. 2018;39:619-626 pubmed 出版商
Wang Y, Li J, Guo S, Ouyang Y, Yin L, Liu S, et al. Lin28B facilitates the progression and metastasis of pancreatic ductal adenocarcinoma. Oncotarget. 2017;8:60414-60428 pubmed 出版商
Tsuboi M, Taniuchi K, Shimizu T, Saito M, Saibara T. The transcription factor HOXB7 regulates ERK kinase activity and thereby stimulates the motility and invasiveness of pancreatic cancer cells. J Biol Chem. 2017;292:17681-17702 pubmed 出版商
Liu W, Zhang B, Hu Q, Qin Y, Xu W, Shi S, et al. A new facet of NDRG1 in pancreatic ductal adenocarcinoma: Suppression of glycolytic metabolism. Int J Oncol. 2017;50:1792-1800 pubmed 出版商
Huang Y, Yang C, Wei P, Huynh T, Whang Peng J, Meng T, et al. Ovatodiolide suppresses colon tumorigenesis and prevents polarization of M2 tumor-associated macrophages through YAP oncogenic pathways. J Hematol Oncol. 2017;10:60 pubmed 出版商
Liang C, Qin Y, Zhang B, Ji S, Shi S, Xu W, et al. Oncogenic KRAS Targets MUC16/CA125 in Pancreatic Ductal Adenocarcinoma. Mol Cancer Res. 2017;15:201-212 pubmed 出版商
Kobayashi T, Nakazono K, Tokuda M, Mashima Y, Dynlacht B, Itoh H. HDAC2 promotes loss of primary cilia in pancreatic ductal adenocarcinoma. EMBO Rep. 2017;18:334-343 pubmed 出版商
Liang C, Qin Y, Zhang B, Ji S, Shi S, Xu W, et al. ARF6, induced by mutant Kras, promotes proliferation and Warburg effect in pancreatic cancer. Cancer Lett. 2017;388:303-311 pubmed 出版商
Tanaka T, Ikegami Y, Nakazawa H, Kuriyama N, Oki M, Hanai J, et al. Low-Dose Farnesyltransferase Inhibitor Suppresses HIF-1? and Snail Expression in Triple-Negative Breast Cancer MDA-MB-231 Cells In Vitro. J Cell Physiol. 2017;232:192-201 pubmed 出版商
Wang Y, Chen Y, Liu S, Ye Y, Jiao H, Wang S, et al. MiR-384 inhibits human colorectal cancer metastasis by targeting KRAS and CDC42. Oncotarget. 2016;7:84826-84838 pubmed 出版商
Song H, Biancucci M, Kang H, O Callaghan C, Park S, Principe D, et al. SIRT2 deletion enhances KRAS-induced tumorigenesis in vivo by regulating K147 acetylation status. Oncotarget. 2016;7:80336-80349 pubmed 出版商
Ye Y, Wu P, Gu C, Deng D, Jiao H, Li T, et al. miR-450b-5p induced by oncogenic KRAS is required for colorectal cancer progression. Oncotarget. 2016;7:61312-61324 pubmed 出版商
Wang S, Zhang W, Wu X, Zhang M, Weng M, Zhou D, et al. Long non-coding RNA Malat1 promotes gallbladder cancer development by acting as a molecular sponge to regulate miR-206. Oncotarget. 2016;7:37857-37867 pubmed 出版商
Kim E, Ilic N, Shrestha Y, Zou L, Kamburov A, Zhu C, et al. Systematic Functional Interrogation of Rare Cancer Variants Identifies Oncogenic Alleles. Cancer Discov. 2016;6:714-26 pubmed 出版商
Ramraj S, Aravindan S, Somasundaram D, Herman T, Natarajan M, Aravindan N. Serum-circulating miRNAs predict neuroblastoma progression in mouse model of high-risk metastatic disease. Oncotarget. 2016;7:18605-19 pubmed 出版商
Ji H, Lee J, Wang Y, Pang Y, Zhang T, Xia Y, et al. EGFR phosphorylates FAM129B to promote Ras activation. Proc Natl Acad Sci U S A. 2016;113:644-9 pubmed 出版商
Xu Q, Fu R, Yin G, Liu X, Liu Y, Xiang M. Microarray-based gene expression profiling reveals genes and pathways involved in the oncogenic function of REG3A on pancreatic cancer cells. Gene. 2016;578:263-73 pubmed 出版商
Chu P, Yang M, Kulp S, Salunke S, Himmel L, Fang C, et al. Regulation of oncogenic KRAS signaling via a novel KRAS-integrin-linked kinase-hnRNPA1 regulatory loop in human pancreatic cancer cells. Oncogene. 2016;35:3897-908 pubmed 出版商
Liu W, Ning R, Chen R, Huang X, Dai Q, Hu J, et al. Aspafilioside B induces G2/M cell cycle arrest and apoptosis by up-regulating H-Ras and N-Ras via ERK and p38 MAPK signaling pathways in human hepatoma HepG2 cells. Mol Carcinog. 2016;55:440-57 pubmed 出版商
图像
图像 1 :
武汉三鹰 12063-1-AP 图像 1
The KRAS antibody from Proteintech is a rabbit polyclonal antibody to a recombinant protein of human KRAS. This antibody recognizes human,mouse,rat antigen. The KRAS antibody has been validated for the following applications: FC, IF, IHC, IP, WB, ELISA analysis.
产品信息
目录号 :
12063-1-AP
AntigenName :
KRAS
Package :
150UL
价格 :
299美元
Exsists20ul :
20ul trial size available
FullName :
v-Ki-ras2 Kirsten rat sarcoma viral oncogene homolog
免疫原 :
重组蛋白
物种 :
人类, 小鼠, 大鼠
宿主 :
IsConjugated :
未共轭
AntigenSpecies :
人类
应用 :
免疫印迹, 免疫沉淀, 免疫组化, IF, FC, 酶联免疫吸附测定
Clonlity :
多克隆
抗体亚型 :
IgG
同义词 :
C K RAS, c Ki ras, GTPase KRas, K Ras 2, K RAS2A, K RAS2B, K RAS4A, K RAS4B, KI RAS, KRAS, KRAS1, KRAS2, KRAS2A, KRAS2B, KRAS2B speicifc, Krasa, Krasb, NS3, RASK2
PrimaryOrSecondary :
Primary
抗体缓冲液 :
PBS含0.1%叠氮化钠和50% 甘油pH值7.3
GenBank登录号 :
BC013572
类别 :
Binding Proteins;Cell Cycle;Disease Related;Membrane Proteins;Oncogene(s) and Tumor Suppressor(s);Signal transduction;
PurifyMethod :
抗原亲和纯化
NewAb :
False
IsSellable :
True
Feature :
siRNA
AppTiter :
FC 1:0;IF 1:50;免疫组化1:800;免疫沉淀1:1000;免疫印迹1:5000;
更多信息或购买 :
公司信息
武汉三鹰
武汉市洪山区关山二路关东科技园7-4#,402室
Service@ptglab.com
http://www.ptgcn.com
4006 900 926, 027-87531629 / 027-87531627
公司总部: 美国
Proteintech Group致力于开发针对所有人类蛋白的抗体,我们将这项计划命名为人类抗体组计划。Proteintech Group在科研领域享有良好声誉, 迄今已生产出针对10,000种不同人类蛋白的10,000种抗体。同时,Proteintech Group也提供多种客户订单服务:克隆,表达,多肽合成,多抗及单抗生产,以满足您的不同需求。

Proteintech Group的创建者都是资深科研人员,我们非常理解科学家们对工作尽善尽美的追求,我们也以同样的标准来要求我们的产品。作为科研领域的成员之一,我们要做每一项科研工作背后的默默支持者,为科学家们提供质量优良,价格合理的产品和服务。

我们承诺为您提供高品质的抗体及相关产品,让您不再担忧试剂的品质,让您能够倾注您全部的创造力,才华和精力于研究当中。我们坚信只有您成功了,我们才会成功。