产品简要
公司名称 :
武汉三鹰
产品类型 :
抗体
产品名称 :
胱氨酸-天冬氨酸蛋白酶8/p43/p18
目录 :
13423-1-AP
规格 :
150UL
价格 :
299美元
克隆性 :
多克隆
宿主 :
domestic rabbit
共轭标签 :
未共轭
反应物种 :
人类, 小鼠, 大鼠
应用 :
免疫印迹, 酶联免疫吸附测定, 免疫组化, 免疫细胞化学, 免疫沉淀
更多信息或购买 :
文章摘录数: 114
出版应用/物种/样本/稀释参考文献
  • 免疫组化; 小鼠; 图 3b
Li J, Chen K, Li S, Liu T, Wang F, Xia Y, et al. Pretreatment with Fucoidan from Fucus vesiculosus Protected against ConA-Induced Acute Liver Injury by Inhibiting Both Intrinsic and Extrinsic Apoptosis. PLoS ONE. 2016;11:e0152570 pubmed 出版商
  • 免疫印迹; 大鼠; 1:800; 图 5a
Kong F, Wang H, Guo J, Peng M, Ji H, Yang H, et al. Hsp70 suppresses apoptosis of BRL cells by regulating the expression of Bcl-2, cytochrome C, and caspase 8/3. In Vitro Cell Dev Biol Anim. 2016;52:568-75 pubmed 出版商
  • 免疫印迹; 人类; 1:1000; 图 6a
Zhang W, Shi H, Zhang M, Liu B, Mao S, Li L, et al. Poly C binding protein 1 represses autophagy through downregulation of LC3B to promote tumor cell apoptosis in starvation. Int J Biochem Cell Biol. 2016;73:127-136 pubmed 出版商
Kang D, Zuo W, Wu Q, Zhu Q, Liu P. Inhibition of Specificity Protein 1 Is Involved in Phloretin-Induced Suppression of Prostate Cancer. Biomed Res Int. 2020;2020:1358674 pubmed 出版商
Hu Z, Wang H, Fu Y, Ma K, Ma X, Wang J. Gentiopicroside Inhibits Cell Growth and Migration on Cervical Cancer via the Reciprocal MAPK/Akt Signaling Pathways. Nutr Cancer. 2020;:1-12 pubmed 出版商
Guo L, Liu S, Yang Q, Liu H, Xu L, Hao Y, et al. Effect of Thymoquinone on Acute Kidney Injury Induced by Sepsis in BALB/c Mice. Biomed Res Int. 2020;2020:1594726 pubmed 出版商
Liu J, Deng X, Sun X, Dong J, Huang J. Inhibition of autophagy enhances timosaponin AIII-induced lung cancer cell apoptosis and anti-tumor effect in vitro and in vivo. Life Sci. 2020;257:118040 pubmed 出版商
Dong P, Fu H, Chen L, Zhang S, Zhang X, Li H, et al. PCNP promotes ovarian cancer progression by accelerating β-catenin nuclear accumulation and triggering EMT transition. J Cell Mol Med. 2020;: pubmed 出版商
Guo Y, Zhu H, Weng M, Chen B, Wang C, Sun L. Baohuoside-1 targeting mTOR inducing apoptsis to inhibit hepatocellular carcinoma proliferation, invasion and migration. Biomed Pharmacother. 2020;128:110366 pubmed 出版商
Yang T, Fan T, Xu B. Norfloxacin induces apoptosis and necroptosis in human corneal epithelial cells. Toxicol In Vitro. 2020;66:104868 pubmed 出版商
Mao L, Kan Y, Li B, Ma S, Liu Y, Yang D, et al. Combination Therapy of Prostate Cancer by Oncolytic Adenovirus Harboring Interleukin 24 and Ionizing Radiation. Front Oncol. 2020;10:421 pubmed 出版商
He S, Li A, Zhang W, Zhang L, Liu Y, Li K, et al. An integrated transcriptomics and network pharmacology approach to exploring the mechanism of adriamycin-induced kidney injury. Chem Biol Interact. 2020;325:109096 pubmed 出版商
Liu X, Zhang Y, Wu S, Xu M, Shen Y, Yu M, et al. Palmatine induces G2/M phase arrest and mitochondrial-associated pathway apoptosis in colon cancer cells by targeting AURKA. Biochem Pharmacol. 2020;175:113933 pubmed 出版商
Du J, Li J, Gao M, Guan Q, Liu T, Wu Y, et al. MAY, a novel tubulin inhibitor, induces cell apoptosis in A549 and A549/Taxol cells and inhibits epithelial-mesenchymal transition in A549/Taxol cells. Chem Biol Interact. 2020;323:109074 pubmed 出版商
Su W, Zhao J, Fan T. Dose- and Time-Dependent Cytotoxicity of Carteolol in Corneal Endothelial Cells and the Underlying Mechanisms. Front Pharmacol. 2020;11:202 pubmed 出版商
Lin H, HAN H, Wang Y, He D, Sun W, Feng L, et al. Shikonin and 4-hydroxytamoxifen synergistically inhibit the proliferation of breast cancer cells through activating apoptosis signaling pathway in vitro and in vivo. Chin Med. 2020;15:23 pubmed 出版商
Wang N, Liu H, Liu G, Li M, He X, Yin C, et al. Yeast β-D-glucan exerts antitumour activity in liver cancer through impairing autophagy and lysosomal function, promoting reactive oxygen species production and apoptosis. Redox Biol. 2020;32:101495 pubmed 出版商
Gao L, Qian B, Chen H, Wang A, Li Q, Li J, et al. Hic-5 deficiency attenuates hepatic ischemia reperfusion injury through TLR4/NF-κB signaling pathways. Life Sci. 2020;249:117517 pubmed 出版商
Yang B, Bai H, Sa Y, Zhu P, Liu P. Inhibiting EMT, stemness and cell cycle involved in baicalin-induced growth inhibition and apoptosis in colorectal cancer cells. J Cancer. 2020;11:2303-2317 pubmed 出版商
Man S, Yang L, Xiang H, Lu G, Wang Y, Liu C, et al. Antihypertensive and renal protective effect of Shunaoxin pill combined with captopril on spontaneous hypertension rats. Biomed Pharmacother. 2020;125:109977 pubmed 出版商
Liu Q, Guo X, Huang Z, He Q, Zhu D, Zhang S, et al. Anti-neuroinflammatory effects of dimethylaminomylide (DMAMCL, i.e., ACT001) are associated with attenuating the NLRP3 inflammasome in MPTP-induced Parkinson disease in mice. Behav Brain Res. 2020;383:112539 pubmed 出版商
Wu K, Liu H, Wang Y, He J, Xu S, Chen Y, et al. SETDB1-Mediated Cell Fate Transition between 2C-Like and Pluripotent States. Cell Rep. 2020;30:25-36.e6 pubmed 出版商
Zhou Y, Fu X, Guan Y, Gong M, He K, Huang B. 1,3-Dicaffeoylquinic acid targeting 14-3-3 tau suppresses human breast cancer cell proliferation and metastasis through IL6/JAK2/PI3K pathway. Biochem Pharmacol. 2020;172:113752 pubmed 出版商
Li Y, Wang C, Lu J, Huang K, Han Y, Chen J, et al. PPAR δ inhibition protects against palmitic acid-LPS induced lipidosis and injury in cultured hepatocyte L02 cell. Int J Med Sci. 2019;16:1593-1603 pubmed 出版商
Sun Y, Gong J, Cao Y. Multi-Walled Carbon Nanotubes (MWCNTs) Activate Apoptotic Pathway Through ER Stress: Does Surface Chemistry Matter?. Int J Nanomedicine. 2019;14:9285-9294 pubmed 出版商
Jiang J, Wang X, Gao G, Liu X, Chang H, Xiong R, et al. Silencing of lncRNA HOXA11-AS inhibits cell migration, invasion, proliferation, and promotes apoptosis in human glioma cells via upregulating microRNA-125a: in vitro and in vivo studies. Am J Transl Res. 2019;11:6382-6392 pubmed
Peng F, Zhang N, Wang C, Wang X, Huang W, Peng C, et al. Aconitine induces cardiomyocyte damage by mitigating BNIP3-dependent mitophagy and the TNFα-NLRP3 signalling axis. Cell Prolif. 2019;:e12701 pubmed 出版商
Xin X, Zhang R, Yuan X, Liu L. Mechanisms of IFNalpha-1a-Induced Apoptosis in a Laryngeal Cancer Cell Line. Med Sci Monit. 2019;25:7100-7114 pubmed 出版商
Yao Y, Zhang J, Tian P, Li L, Huang X, Nawutayi M, et al. Passive smoking induces rat testicular injury via the FAS/FASL pathway. Drug Chem Toxicol. 2019;:1-9 pubmed 出版商
Zhang Q, Cao W, Wang X, Zhang M, Lu X, Chen J, et al. Genistein inhibits nasopharyngeal cancer stem cells through sonic hedgehog signaling. Phytother Res. 2019;: pubmed 出版商
Wu D, Li M, Gao Y, Tian W, Li J, Zhang Q, et al. Peptide V3 Inhibits the Growth of Human Hepatocellular Carcinoma by Inhibiting the Ras/Raf/MEK/ERK Signaling Pathway. J Cancer. 2019;10:1693-1706 pubmed 出版商
Xu W, Hu G, Da Costa C, Tang J, Li Q, Du L, et al. Long noncoding RNA UBE2R2-AS1 promotes glioma cell apoptosis via targeting the miR-877-3p/TLR4 axis. Onco Targets Ther. 2019;12:3467-3480 pubmed 出版商
Huang Y, Ren A, Wang L, Jin L, Lin S, Li Z, et al. Casp8 hypomethylation and neural tube defects in association with polycyclic aromatic hydrocarbon exposure. Clin Epigenetics. 2019;11:72 pubmed 出版商
Yang H, Qiu B, Chen S, Xun Y, Pan Y, Chen M, et al. Soluble CXCL16 promotes TNF-α-induced apoptosis in DLBCL via the AMAD10-NF-κB regulatory feedback loop. Cell Biol Int. 2019;: pubmed 出版商
Li Z, Chen S, Chen S, Huang D, Ma K, Shao Z. Moderate activation of Wnt/β-catenin signaling promotes the survival of rat nucleus pulposus cells via regulating apoptosis, autophagy, and senescence. J Cell Biochem. 2019;120:12519-12533 pubmed 出版商
Yan X, Zhong X, Yu S, Zhang L, Liu Y, Zhang Y, et al. p62 aggregates mediated Caspase 8 activation is responsible for progression of ovarian cancer. J Cell Mol Med. 2019;23:4030-4042 pubmed 出版商
Liao Y, Hussain T, Liu C, Cui Y, Wang J, Yao J, et al. Endoplasmic Reticulum Stress Induces Macrophages to Produce IL-1β During Mycobacterium bovis Infection via a Positive Feedback Loop Between Mitochondrial Damage and Inflammasome Activation. Front Immunol. 2019;10:268 pubmed 出版商
Li H, Dai Y, Luo Z, Nie D. Cloning of a new testis-enriched gene C4orf22 and its role in cell cycle and apoptosis in mouse spermatogenic cells. Mol Biol Rep. 2019;: pubmed 出版商
Shi J, Li J, Su W, Zhao S, Li H, Lei L. Loss of periodontal ligament fibroblasts by RIPK3-MLKL-mediated necroptosis in the progress of chronic periodontitis. Sci Rep. 2019;9:2902 pubmed 出版商
Tian W, Guo H, Li C, Cao W, Wang X, Mo D, et al. PFKFB3 promotes endotoxemia-induced myocardial dysfunction through inflammatory signaling and apoptotic induction. Toxicol Appl Pharmacol. 2019;368:26-36 pubmed 出版商
Li Z, Yu Y, Wang M, Xu H, Han B, Jiang P, et al. Anti-breast Cancer Activity of SPG-56 from Sweet Potato in MCF-7 Bearing Mice in Situ through Promoting Apoptosis and Inhibiting Metastasis. Sci Rep. 2019;9:146 pubmed 出版商
He Y, Xia Z, Yu D, Wang J, Jin L, Huang D, et al. Hepatoprotective effects and structure-activity relationship of five flavonoids against lipopolysaccharide/d-galactosamine induced acute liver failure in mice. Int Immunopharmacol. 2019;68:171-178 pubmed 出版商
Ge M, Zhang L, Cao L, Xie C, Li X, Li Y, et al. Sulforaphane inhibits gastric cancer stem cells via suppressing sonic hedgehog pathway. Int J Food Sci Nutr. 2019;70:570-578 pubmed 出版商
Zhang D, Zhang J, Zeng J, Li Z, Zuo H, Huang C, et al. Nano-Gold Loaded with Resveratrol Enhance the Anti-Hepatoma Effect of Resveratrol In Vitro and In Vivo. J Biomed Nanotechnol. 2019;15:288-300 pubmed 出版商
Li Y, Zheng Q, Sun D, Cui X, CHEN S, Bulbul A, et al. Dehydroepiandrosterone stimulates inflammation and impairs ovarian functions of polycystic ovary syndrome. J Cell Physiol. 2019;234:7435-7447 pubmed 出版商
Li S, Zhao H, Wang Y, Shao Y, Liu J, Xing M. Arsenic-induced cardiotoxicity correlates with mitochondrial damage and trace elements imbalance in broiler chickens. Poult Sci. 2019;98:734-744 pubmed 出版商
Fan J, Wu M, Wang J, Ren D, Zhao J, Yang G. 1,7-Bis(4-hydroxyphenyl)-1,4-heptadien-3-one induces lung cancer cell apoptosis via the PI3K/Akt and ERK1/2 pathways. J Cell Physiol. 2019;234:6336-6349 pubmed 出版商
Mao J, Yi M, Wang R, Huang Y, Chen M. Protective Effects of Costunolide Against D-Galactosamine and Lipopolysaccharide-Induced Acute Liver Injury in Mice. Front Pharmacol. 2018;9:1469 pubmed 出版商
Hong X, Li S, Li W, Xie M, Wei Z, Guo H, et al. Disruption of protein neddylation with MLN4924 attenuates paclitaxel-induced apoptosis and microtubule polymerization in ovarian cancer cells. Biochem Biophys Res Commun. 2018;: pubmed 出版商
Li L, Wang L, Cheng Y, Cao Z, Zhang X, Guo X. Discovery and Characterization of 4-Hydroxy-2-pyridone Derivative Sambutoxin as a Potent and Promising Anticancer Drug Candidate: Activity and Molecular Mechanism. Mol Pharm. 2018;15:4898-4911 pubmed 出版商
Zhao W, Che C, Liu K, Zhang J, Jiang N, Yuan K, et al. Fenretinide Inhibits Neutrophil Recruitment and IL-1β Production in Aspergillus fumigatus Keratitis. Cornea. 2018;37:1579-1585 pubmed 出版商
Liu Y, Fan D. Ginsenoside Rg5 induces apoptosis and autophagy via the inhibition of the PI3K/Akt pathway against breast cancer in a mouse model. Food Funct. 2018;9:5513-5527 pubmed 出版商
Zhang M, Ding G, Zhou L, Shen T, Xu X, Zhao T, et al. Interferon Gamma Inhibits CXCL8-Induced Proliferation and Migration of Pancreatic Cancer BxPC-3 Cell Line via a RhoGDI2/Rac1/NF-κB Signaling Pathway. J Interferon Cytokine Res. 2018;38:413-422 pubmed 出版商
Chen Y, Li Y, Wang X, Meng Y, Zhang Q, Zhu J, et al. Phenethyl isothiocyanate inhibits colorectal cancer stem cells by suppressing Wnt/β-catenin pathway. Phytother Res. 2018;32:2447-2455 pubmed 出版商
Wu X, Guo Y, Min X, Pei L, Chen X. Neferine, a Bisbenzylisoquinoline Alkaloid, Ameliorates Dextran Sulfate Sodium-Induced Ulcerative Colitis. Am J Chin Med. 2018;46:1263-1279 pubmed 出版商
You C, Zhang S, Sun Y, Zhang S, Tang G, Tang F, et al. β-catenin decreases acquired TRAIL resistance in non-small-cell lung cancer cells by regulating the redistribution of death receptors. Int J Oncol. 2018;53:2258-2268 pubmed 出版商
Zheng Q, Zhou F, Cui X, Liu M, Li Y, Liu S, et al. Novel Serum Biomarkers Detected by Protein Array in Polycystic Ovary Syndrome with Low Progesterone Level. Cell Physiol Biochem. 2018;46:2297-2310 pubmed 出版商
Wu D, Gao Y, Li T, Wang D, Lu D, Liu S, et al. PEST-containing nuclear protein mediates the proliferation, migration, and invasion of human neuroblastoma cells through MAPK and PI3K/AKT/mTOR signaling pathways. BMC Cancer. 2018;18:499 pubmed 出版商
Liu J, Zhao H, Wang Y, Shao Y, Li J, Xing M. Alterations of antioxidant indexes and inflammatory cytokine expression aggravated hepatocellular apoptosis through mitochondrial and death receptor-dependent pathways in Gallus gallus exposed to arsenic and copper. Environ Sci Pollut Res Int. 2018;25:15462-15473 pubmed 出版商
Guo Y, Wu X, Wu Q, Lu Y, Shi J, Chen X. Dihydrotanshinone I, a natural product, ameliorates DSS-induced experimental ulcerative colitis in mice. Toxicol Appl Pharmacol. 2018;344:35-45 pubmed 出版商
Che C, Liu J, Yang J, Ma L, Bai N, Zhang Q. Osteopontin is essential for IL-1β production and apoptosis in peri-implantitis. Clin Implant Dent Relat Res. 2018;20:384-392 pubmed 出版商
Li X, Meng Y, Xie C, Zhu J, Wang X, Li Y, et al. Diallyl Trisulfide inhibits breast cancer stem cells via suppression of Wnt/β-catenin pathway. J Cell Biochem. 2018;119:4134-4141 pubmed 出版商
Wang J, Tian L, Khan M, Zhang L, Chen Q, Zhao Y, et al. Ginsenoside Rg3 sensitizes hypoxic lung cancer cells to cisplatin via blocking of NF-κB mediated epithelial-mesenchymal transition and stemness. Cancer Lett. 2018;415:73-85 pubmed 出版商
Xiao Y, Tian C, Huang T, Han B, Wang M, Ma H, et al. 8-Cetylberberine inhibits growth of lung cancer in vitro and in vivo. Life Sci. 2018;192:259-269 pubmed 出版商
Wu J, Xing C, Zhang L, Mao H, Chen X, Liang M, et al. Autophagy promotes fibrosis and apoptosis in the peritoneum during long-term peritoneal dialysis. J Cell Mol Med. 2018;22:1190-1201 pubmed 出版商
Yin S, Du W, Wang F, Han B, Cui Y, Yang D, et al. MicroRNA-326 sensitizes human glioblastoma cells to curcumin via the SHH/GLI1 signaling pathway. Cancer Biol Ther. 2018;19:260-270 pubmed 出版商
Mehmood T, Maryam A, Tian X, Khan M, Ma T. Santamarine Inhibits NF-?B and STAT3 Activation and Induces Apoptosis in HepG2 Liver Cancer Cells via Oxidative Stress. J Cancer. 2017;8:3707-3717 pubmed 出版商
Song L, Wang Z, Wang Y, Guo D, Yang J, Chen L, et al. Natural Cyclopeptide RA-XII, a New Autophagy Inhibitor, Suppresses Protective Autophagy for Enhancing Apoptosis through AMPK/mTOR/P70S6K Pathways in HepG2 Cells. Molecules. 2017;22: pubmed 出版商
Zheng Q, Li Y, Zhang D, Cui X, Dai K, Yang Y, et al. ANP promotes proliferation and inhibits apoptosis of ovarian granulosa cells by NPRA/PGRMC1/EGFR complex and improves ovary functions of PCOS rats. Cell Death Dis. 2017;8:e3145 pubmed 出版商
Li S, Zhao H, Wang Y, Shao Y, Li J, Liu J, et al. The inflammatory responses in Cu-mediated elemental imbalance is associated with mitochondrial fission and intrinsic apoptosis in Gallus gallus heart. Chemosphere. 2017;189:489-497 pubmed 出版商
Yuan K, Zhao G, Che C, Li C, Lin J, Zhu G, et al. Dectin-1 is essential for IL-1? production through JNK activation and apoptosis in Aspergillus fumigatus keratitis. Int Immunopharmacol. 2017;52:168-175 pubmed 出版商
Wang D, Kong X, Li Y, Qian W, Ma J, Wang D, et al. Curcumin inhibits bladder cancer stem cells by suppressing Sonic Hedgehog pathway. Biochem Biophys Res Commun. 2017;493:521-527 pubmed 出版商
Tang Q, Ji F, Wang J, Guo L, Li Y, Bao Y. Quercetin exerts synergetic anti-cancer activity with 10-hydroxy camptothecin. Eur J Pharm Sci. 2017;109:223-232 pubmed 出版商
Yan X, Li Y, Yu H, Wang W, Wu C, Yang Y, et al. Epigallocatechin-3-gallate inhibits H2O2-induced apoptosis in Mouse Vascular Smooth Muscle Cells via 67kD Laminin Receptor. Sci Rep. 2017;7:7774 pubmed 出版商
Wu B, Cui J, Yang X, Liu Z, Song F, Li L, et al. Cytoplasmic fragment of CD147 generated by regulated intramembrane proteolysis contributes to HCC by promoting autophagy. Cell Death Dis. 2017;8:e2925 pubmed 出版商
Zhu J, Wang S, Chen Y, Li X, Jiang Y, Yang X, et al. miR-19 targeting of GSK3β mediates sulforaphane suppression of lung cancer stem cells. J Nutr Biochem. 2017;44:80-91 pubmed 出版商
Yang Y, Gong X, Huang L, Wang Z, Wan R, Zhang P, et al. Diosmetin exerts anti-oxidative, anti-inflammatory and anti-apoptotic effects to protect against endotoxin-induced acute hepatic failure in mice. Oncotarget. 2017;8:30723-30733 pubmed 出版商
Xie X, Zhao N, Xu Q, Yang X, Xia W, Chen Q, et al. Relaxin attenuates aristolochic acid induced human tubular epithelial cell apoptosis in vitro by activation of the PI3K/Akt signaling pathway. Apoptosis. 2017;22:769-776 pubmed 出版商
Wang X, Cao W, Zhang J, Yan M, Xu Q, Wu X, et al. A covalently bound inhibitor triggers EZH2 degradation through CHIP-mediated ubiquitination. EMBO J. 2017;36:1243-1260 pubmed 出版商
Wei H, Gao Z, Zheng L, Zhang C, Liu Z, Yang Y, et al. Protective Effects of Fucoidan on A?25-35 and d-Gal-Induced Neurotoxicity in PC12 Cells and d-Gal-Induced Cognitive Dysfunction in Mice. Mar Drugs. 2017;15: pubmed 出版商
Wang H, Xu Y, Wang M, Cheng C, Bian R, Yuan H, et al. Protective effect of naringin against the LPS-induced apoptosis of PC12 cells: Implications for the treatment of neurodegenerative disorders. Int J Mol Med. 2017;39:819-830 pubmed 出版商
Zhu J, Yang X, Chen Y, Jiang Y, Wang S, Li Y, et al. Curcumin Suppresses Lung Cancer Stem Cells via Inhibiting Wnt/?-catenin and Sonic Hedgehog Pathways. Phytother Res. 2017;31:680-688 pubmed 出版商
Huang T, Xiao Y, Yi L, Li L, Wang M, Tian C, et al. Coptisine from Rhizoma Coptidis Suppresses HCT-116 Cells-related Tumor Growth in vitro and in vivo. Sci Rep. 2017;7:38524 pubmed 出版商
Tan M, Cao X, Li P, Zhai Y, Zhou Y, Liu Y, et al. Effectively enhancing cytotoxic and apoptotic effects of alpha-momorcharin by integrating a heparin-binding peptide. Biotechnol Appl Biochem. 2017;64:918-926 pubmed 出版商
Wang X, Sun Y, Zhao C, Qu F, Zhao Y. 12-Chloracetyl-PPD, a novel dammarane derivative, shows anti-cancer activity via delay the progression of cell cycle G2/M phase and reactive oxygen species-mediate cell apoptosis. Eur J Pharmacol. 2017;798:49-56 pubmed 出版商
Yuan G, Hua B, Yang Y, Xu L, Cai T, Sun N, et al. The Circadian Gene Clock Regulates Bone Formation Via PDIA3. J Bone Miner Res. 2017;32:861-871 pubmed 出版商
Zhu J, Jiang Y, Yang X, Wang S, Xie C, Li X, et al. Wnt/?-catenin pathway mediates (-)-Epigallocatechin-3-gallate (EGCG) inhibition of lung cancer stem cells. Biochem Biophys Res Commun. 2017;482:15-21 pubmed 出版商
Nan A, Chen L, Zhang N, Liu Z, Yang T, Wang Z, et al. A novel regulatory network among LncRpa, CircRar1, MiR-671 and apoptotic genes promotes lead-induced neuronal cell apoptosis. Arch Toxicol. 2017;91:1671-1684 pubmed 出版商
Cui Y, Zhao D, Sreevatsan S, Liu C, Yang W, Song Z, et al. Mycobacterium bovis Induces Endoplasmic Reticulum Stress Mediated-Apoptosis by Activating IRF3 in a Murine Macrophage Cell Line. Front Cell Infect Microbiol. 2016;6:182 pubmed 出版商
Tang Q, Ji F, Sun W, Wang J, Guo J, Guo L, et al. Combination of baicalein and 10-hydroxy camptothecin exerts remarkable synergetic anti-cancer effects. Phytomedicine. 2016;23:1778-1786 pubmed 出版商
Shi W, Cao C, Liu L. Interferon ? Induces the Apoptosis of Cervical Cancer HeLa Cells by Activating both the Intrinsic Mitochondrial Pathway and Endoplasmic Reticulum Stress-Induced Pathway. Int J Mol Sci. 2016;17: pubmed
Liu Z, Shi Q, Song X, Wang Y, Wang Y, Song E, et al. Activating Transcription Factor 4 (ATF4)-ATF3-C/EBP Homologous Protein (CHOP) Cascade Shows an Essential Role in the ER Stress-Induced Sensitization of Tetrachlorobenzoquinone-Challenged PC12 Cells to ROS-Mediated Apoptosis via Death Receptor 5 (DR5). Chem Res Toxicol. 2016;29:1510-8 pubmed 出版商
Yuan S, Wen J, Cheng J, Shen W, Zhou S, Yan W, et al. Age-associated up-regulation of EGR1 promotes granulosa cell apoptosis during follicle atresia in mice through the NF-κB pathway. Cell Cycle. 2016;15:2895-2905 pubmed
Li X, Zhu F, Jiang J, Sun C, Zhong Q, Shen M, et al. Simultaneous inhibition of the ubiquitin-proteasome system and autophagy enhances apoptosis induced by ER stress aggravators in human pancreatic cancer cells. Autophagy. 2016;12:1521-37 pubmed 出版商
Zou M, Duan Y, Wang P, Gao R, Chen X, Ou Y, et al. DYT-40, a novel synthetic 2-styryl-5-nitroimidazole derivative, blocks malignant glioblastoma growth and invasion by inhibiting AEG-1 and NF-κB signaling pathways. Sci Rep. 2016;6:27331 pubmed 出版商
Lu Y, Li P, Li Y, Luo F, Guo C, Lin B, et al. Enhanced anti-tumor activity of trichosanthin after combination with a human-derived cell-penetrating peptide, and a possible mechanism of activity. Fitoterapia. 2016;112:183-90 pubmed 出版商
Zhao L, Wen Q, Yang G, Huang Z, Shen T, Li H, et al. Apoptosis induction of dehydrobruceine B on two kinds of human lung cancer cell lines through mitochondrial-dependent pathway. Phytomedicine. 2016;23:114-22 pubmed 出版商
Ju D, Yamaguchi F, Zhan G, Higuchi T, Asakura T, Morita A, et al. Hyperthermotherapy enhances antitumor effect of 5-aminolevulinic acid-mediated sonodynamic therapy with activation of caspase-dependent apoptotic pathway in human glioma. Tumour Biol. 2016;37:10415-26 pubmed 出版商
Chen K, Dai W, Wang F, Xia Y, Li J, Li S, et al. Inhibitive effects of 15-deoxy-Δ(12),(14)-prostaglandin J2 on hepatoma-cell proliferation through reactive oxygen species-mediated apoptosis. Onco Targets Ther. 2015;8:3585-93 pubmed 出版商
Nie D, Zhang D, Dai J, Zhang M, Zhao X, Xu W, et al. Nicotine Induced Murine Spermatozoa Apoptosis via Up-Regulation of Deubiquitinated RIP1 by Trim27 Promoter Hypomethylation. Biol Reprod. 2016;94:31 pubmed 出版商
Wang L, Wang C, Jia Y, Liu Z, Shu X, Liu K. Resveratrol Increases Anti-Proliferative Activity of Bestatin Through Downregulating P-Glycoprotein Expression Via Inhibiting PI3K/Akt/mTOR Pathway in K562/ADR Cells. J Cell Biochem. 2016;117:1233-9 pubmed 出版商
Song X, Li L, Shi Q, Lehmler H, Fu J, Su C, et al. Polychlorinated Biphenyl Quinone Metabolite Promotes p53-Dependent DNA Damage Checkpoint Activation, S-Phase Cycle Arrest and Extrinsic Apoptosis in Human Liver Hepatocellular Carcinoma HepG2 Cells. Chem Res Toxicol. 2015;28:2160-9 pubmed 出版商
Mao Y, Wang J, Yu F, Cheng J, Li H, Guo C, et al. Ghrelin reduces liver impairment in a model of concanavalin A-induced acute hepatitis in mice. Drug Des Devel Ther. 2015;9:5385-96 pubmed 出版商
Aziz F, Wang X, Liu J, Yan Q. Ginsenoside Rg3 induces FUT4-mediated apoptosis in H. pylori CagA-treated gastric cancer cells by regulating SP1 and HSF1 expressions. Toxicol In Vitro. 2016;31:158-66 pubmed 出版商
Zhang S, Shao S, Song X, Xia C, Yang Y, Zhang P, et al. Protective effects of Forsythia suspense extract with antioxidant and anti-inflammatory properties in a model of rotenone induced neurotoxicity. Neurotoxicology. 2016;52:72-83 pubmed 出版商
Zhang X, Jiang S, Shang B, Jiang H. Effects of histone deacetylase inhibitor trichostatin A combined with cisplatin on apoptosis of A549 cell line. Thorac Cancer. 2015;6:202-8 pubmed 出版商
Peng X, Zhang Y, Wang J, Ji Q. Ethylacetate extract from Tetrastigma hemsleyanum induces apoptosis via the mitochondrial caspase-dependent intrinsic pathway in HepG2 cells. Tumour Biol. 2016;37:865-76 pubmed 出版商
Hu L, Su C, Song X, Shi Q, Fu J, Xia X, et al. Tetrachlorobenzoquinone triggers the cleavage of Bid and promotes the cross-talk of extrinsic and intrinsic apoptotic signalings in pheochromocytoma (PC) 12 cells. Neurotoxicology. 2015;49:149-57 pubmed 出版商
Khan M, Wang B, Wei J, Zhang Y, Li Q, Luan X, et al. CXCR1/2 antagonism with CXCL8/Interleukin-8 analogue CXCL8(3-72)K11R/G31P restricts lung cancer growth by inhibiting tumor cell proliferation and suppressing angiogenesis. Oncotarget. 2015;6:21315-27 pubmed
Wang Y, Yan T, Ma L, Liu B. Effects of the total saponins from Dioscorea nipponica on immunoregulation in aplastic anemia mice. Am J Chin Med. 2015;43:289-303 pubmed 出版商
Huang Y, Du Y, Zhang X, Bai L, Mibrahim M, Zhang J, et al. Down-regulated expression of Annexin A7 induces apoptosis in mouse hepatocarcinoma cell line by the intrinsic mitochondrial pathway. Biomed Pharmacother. 2015;70:146-50 pubmed 出版商
Liu W, Ning R, Chen R, Huang X, Dai Q, Hu J, et al. Aspafilioside B induces G2/M cell cycle arrest and apoptosis by up-regulating H-Ras and N-Ras via ERK and p38 MAPK signaling pathways in human hepatoma HepG2 cells. Mol Carcinog. 2016;55:440-57 pubmed 出版商
Li X, Zhu F, Jiang J, Sun C, Wang X, Shen M, et al. Synergistic antitumor activity of withaferin A combined with oxaliplatin triggers reactive oxygen species-mediated inactivation of the PI3K/AKT pathway in human pancreatic cancer cells. Cancer Lett. 2015;357:219-30 pubmed 出版商
Guo L, Shen Y, Zhao X, Guo L, Yu Z, Wang D, et al. Curcumin combined with oxaliplatin effectively suppress colorectal carcinoma in vivo through inducing apoptosis. Phytother Res. 2015;29:357-65 pubmed 出版商
图像
图像 1 :
武汉三鹰 13423-1-AP 图像 1
The Caspase 8/p43/p18 antibody from Proteintech is a rabbit polyclonal antibody to a recombinant protein of human Caspase 8/p43/p18. This antibody recognizes human, mouse antigen. The Caspase 8/p43/p18 antibody has been validated for the following applications: IF, IHC, IP, WB, ELISA analysis.
产品信息
目录号 :
13423-1-AP
AntigenName :
胱氨酸-天冬氨酸蛋白酶8/p43/p18
Package :
150UL
价格 :
299美元
Exsists20ul :
20ul trial size available
FullName :
caspase 8, apoptosis-related cysteine peptidase
免疫原 :
重组蛋白
物种 :
鸡, 人类, 小鼠, 大鼠
宿主 :
IsConjugated :
未共轭
AntigenSpecies :
人类
应用 :
免疫印迹, 免疫沉淀, 免疫组化, IF, 酶联免疫吸附测定
Clonlity :
多克隆
抗体亚型 :
IgG
同义词 :
Apoptotic protease Mch 5, Casp 8, CASP8, Caspase 8, Caspase 8/p18, caspase8, FADD like ICE, FLICE, ICE like apoptotic protease 5, MACH, MCH5, MORT1 associated ced 3 homolog
PrimaryOrSecondary :
Primary
抗体缓冲液 :
PBS with 0.02% sodium azide and 50% glycerol pH 7.3.
GenBank登录号 :
BC028223
类别 :
Apoptosis;Binding Proteins;Cytoskeleton/Scaffold Proteins;Disease Related;Membrane Proteins;Metabolism;
PurifyMethod :
抗原亲和纯化
NewAb :
False
IsSellable :
True
Feature :
siRNA
AppTiter :
IF 1:25;免疫组化1:200;免疫沉淀1:500;免疫印迹1:500;
更多信息或购买 :
公司信息
武汉三鹰
武汉市洪山区关山二路关东科技园7-4#,402室
Service@ptglab.com
http://www.ptgcn.com
4006 900 926, 027-87531629 / 027-87531627
公司总部: 美国
Proteintech Group致力于开发针对所有人类蛋白的抗体,我们将这项计划命名为人类抗体组计划。Proteintech Group在科研领域享有良好声誉, 迄今已生产出针对10,000种不同人类蛋白的10,000种抗体。同时,Proteintech Group也提供多种客户订单服务:克隆,表达,多肽合成,多抗及单抗生产,以满足您的不同需求。

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