产品简要
公司名称 :
武汉三鹰
产品类型 :
抗体
产品名称 :
NOX4
目录 :
14347-1-AP
规格 :
150UL
价格 :
299美元
克隆性 :
多克隆
宿主 :
domestic rabbit
共轭标签 :
未共轭
反应物种 :
人类, 小鼠
应用 :
免疫印迹, 酶联免疫吸附测定, 免疫组化, 免疫细胞化学, 免疫沉淀, 流式细胞仪
更多信息或购买 :
文章摘录数: 69
出版应用/物种/样本/稀释参考文献
  • 免疫印迹; 小鼠; 1:500; 图 4b
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Chen Z, Sun X, Li X, Xu Z, Yang Y, Lin Z, et al. Polydatin attenuates renal fibrosis in diabetic mice through regulating the Cx32-Nox4 signaling pathway. Acta Pharmacol Sin. 2020;: pubmed 出版商
Chen N, Mu L, Yang Z, Du C, Wu M, Song S, et al. Carbohydrate response element-binding protein regulates lipid metabolism via mTOR complex1 in diabetic nephropathy. J Cell Physiol. 2020;: pubmed 出版商
Zhou B, Qiu Y, Wu N, Chen A, Zhou H, Chen Q, et al. FNDC5 Attenuates Oxidative Stress and NLRP3 Inflammasome Activation in Vascular Smooth Muscle Cells via Activating the AMPK-SIRT1 Signal Pathway. Oxid Med Cell Longev. 2020;2020:6384803 pubmed 出版商
Tan X, Li T, Zhu S, Zhong W, Li F, Wang Y. Induction of SPARC on Oxidative Stress, Inflammatory Phenotype Transformation, and Apoptosis of Human Brain Smooth Muscle Cells Via TGF-β1-NOX4 Pathway. J Mol Neurosci. 2020;: pubmed 出版商
Zhu Y, Zhu C, Yang H, Deng J, Fan D. Protective effect of ginsenoside Rg5 against kidney injury via inhibition of NLRP3 inflammasome activation and the MAPK signaling pathway in high-fat diet/streptozotocin-induced diabetic mice. Pharmacol Res. 2020;155:104746 pubmed 出版商
Cao L, Li X, XU R, Yao K, Yang W, Zhu H, et al. DUOX2, a common modulator in preventive effects of monoamine-based antidepressants on water immersion restraint stress- and indomethacin- induced gastric mucosal damage. Eur J Pharmacol. 2020;876:173058 pubmed 出版商
Li C, Sun X, Li A, Mo M, Zhao Z. S-Allylmercaptocysteine attenuates Bleomycin-induced pulmonary fibrosis in mice via suppressing TGF-β1/Smad and oxidative stress pathways. Int Immunopharmacol. 2020;79:106110 pubmed 出版商
Zhang Q, Zhao S, Zheng W, Fu H, Wu T, Hu F. Plumbagin attenuated oxygen-glucose deprivation/reoxygenation-induced injury in human SH-SY5Y cells by inhibiting NOX4-derived ROS-activated NLRP3 inflammasome. Biosci Biotechnol Biochem. 2020;84:134-142 pubmed 出版商
Zhang Q, Wang Z, Miao L, Wang Y, Chang L, Guo W, et al. Neuroprotective Effect of SCM-198 through Stabilizing Endothelial Cell Function. Oxid Med Cell Longev. 2019;2019:7850154 pubmed 出版商
Zhang Z, He J, Zhao Y, Chen H, Tan N. Asiatic acid prevents renal fibrosis in UUO rats via promoting the production of 15d-PGJ2, an endogenous ligand of PPAR-γ. Acta Pharmacol Sin. 2019;: pubmed 出版商
Guo Y, You Y, Lv D, Yan J, Shang F, Wang X, et al. Inducible nitric oxide synthase contributes to insulin resistance and cardiac dysfunction after burn injury in mice. Life Sci. 2019;239:116912 pubmed 出版商
Muthuramalingam K, Cho M, Kim Y. Cellular senescence and EMT crosstalk in bleomycin-induced pathogenesis of pulmonary fibrosis-an in vitro analysis. Cell Biol Int. 2019;: pubmed 出版商
Zhang J, Cai W, Fan Z, Yang C, Wang W, Xiong M, et al. MicroRNA-24 inhibits the oxidative stress induced by vascular injury by activating the Nrf2/Ho-1 signaling pathway. Atherosclerosis. 2019;290:9-18 pubmed 出版商
Balta E, Hardt R, Liang J, Kirchgessner H, Orlik C, Jahraus B, et al. Spatial oxidation of L-plastin downmodulates actin-based functions of tumor cells. Nat Commun. 2019;10:4073 pubmed 出版商
Chen Z, Sun X, Chen Q, Lan T, Huang K, Xiao H, et al. Connexin32 ameliorates renal fibrosis in diabetic mice by promoting K48-linked Nox4 polyubiquitination and degradation via the inhibition of Smurf1 expression. Br J Pharmacol. 2019;: pubmed 出版商
Yang Q, Wang C, Jin Y, Ma X, Xie T, Wang J, et al. Disocin prevents postmenopausal atherosclerosis in ovariectomized LDLR-/- mice through a PGC-1α/ERα pathway leading to promotion of autophagy and inhibition of oxidative stress, inflammation and apoptosis. Pharmacol Res. 2019;148:104414 pubmed 出版商
Cui C, Xu P, Li G, Qiao Y, Han W, Geng C, et al. Vitamin D receptor activation regulates microglia polarization and oxidative stress in spontaneously hypertensive rats and angiotensin II-exposed microglial cells: Role of renin-angiotensin system. Redox Biol. 2019;26:101295 pubmed 出版商
Xue M, Li T, Wang Y, Chang Y, Cheng Y, Lu Y, et al. Empagliflozin prevents cardiomyopathy via sGC-cGMP-PKG pathway in type 2 diabetes mice. Clin Sci (Lond). 2019;133:1705-1720 pubmed 出版商
Lin J, Fang L, Li H, Li Z, Lyu L, Wang H, et al. Astragaloside IV alleviates doxorubicin induced cardiomyopathy by inhibiting NADPH oxidase derived oxidative stress. Eur J Pharmacol. 2019;:172490 pubmed 出版商
Gao W, Wang W, Zhang J, Deng P, Hu J, Yang J, et al. Allicin ameliorates obesity comorbid depressive-like behaviors: involvement of the oxidative stress, mitochondrial function, autophagy, insulin resistance and NOX/Nrf2 imbalance in mice. Metab Brain Dis. 2019;: pubmed 出版商
Yamaleyeva L, Brosnihan K, Elsangeedy E, McGee C, Shi S, Caudell D, et al. Systemic Outcomes of (Pyr1)-Apelin-13 Infusion at Mid-Late Pregnancy in a Rat Model with Preeclamptic Features. Sci Rep. 2019;9:8579 pubmed 出版商
Zhang C, Han F, Shi M, Sun H, Li Y, Ci Y, et al. MARVELD1 interacting with catalase regulates reactive oxygen species metabolism and mediates the sensitivity to chemotherapeutic drugs in epithelial tumors of the reproductive system. Mol Carcinog. 2019;: pubmed 出版商
Zhang H, Wang J, Wang Y, Gao C, Gu Y, Huang J, et al. Salvianolic Acid A Protects the Kidney against Oxidative Stress by Activating the Akt/GSK-3β/Nrf2 Signaling Pathway and Inhibiting the NF-κB Signaling Pathway in 5/6 Nephrectomized Rats. Oxid Med Cell Longev. 2019;2019:2853534 pubmed 出版商
Zhang J, An H, Ni K, Chen B, Li H, Li Y, et al. Glutathione prevents chronic oscillating glucose intake-induced β-cell dedifferentiation and failure. Cell Death Dis. 2019;10:321 pubmed 出版商
Zhang X, Tan H, Shi Z, Li N, Jia Y, Hao Z. Growth differentiation factor 11 is involved in isoproterenol‑induced heart failure. Mol Med Rep. 2019;19:4109-4118 pubmed 出版商
Chen D, Zang Y, Qiu Y, Zhang F, Chen A, Wang J, et al. BCL6 Attenuates Proliferation and Oxidative Stress of Vascular Smooth Muscle Cells in Hypertension. Oxid Med Cell Longev. 2019;2019:5018410 pubmed 出版商
Han W, Wang C, Yang Z, Mu L, Wu M, Chen N, et al. SRT1720 retards renal fibrosis via inhibition of HIF1α /GLUT1 in diabetic nephropathy. J Endocrinol. 2019;: pubmed 出版商
Song S, Qiu D, Shi Y, Wang S, Zhou X, Chen N, et al. Thioredoxin-interacting protein deficiency alleviates phenotypic alterations of podocytes via inhibition of mTOR activation in diabetic nephropathy. J Cell Physiol. 2019;: pubmed 出版商
Zhang M, Chang Z, Zhao F, Zhang P, Hao Y, Yan L, et al. Protective Effects of 18β-Glycyrrhetinic Acid on Monocrotaline-Induced Pulmonary Arterial Hypertension in Rats. Front Pharmacol. 2019;10:13 pubmed 出版商
Liu B, Rong Y, Sun D, Li W, Chen H, Cao B, et al. Costunolide inhibits pulmonary fibrosis via regulating NF-kB and TGF-β1/Smad2/Nrf2-NOX4 signaling pathways. Biochem Biophys Res Commun. 2019;: pubmed 出版商
Liu P, Zhang H, Hu K, Zhou X, Tang S. Sensory plasticity of carotid body is correlated with oxidative stress in paraventricular nucleus during chronic intermittent hypoxia. J Cell Physiol. 2019;234:13534-13543 pubmed 出版商
Song Q, Zhang Y, Han X, Zhang Y, Zhang X, Gao Y, et al. Potential mechanisms underlying the protective effects of salvianic acid A against atherosclerosis in vivo and vitro. Biomed Pharmacother. 2019;109:945-956 pubmed 出版商
Gao W, Wang W, Liu G, Zhang J, Yang J, Deng Z. Allicin attenuated chronic social defeat stress induced depressive-like behaviors through suppression of NLRP3 inflammasome. Metab Brain Dis. 2019;34:319-329 pubmed 出版商
Hu H, Wang C, Jin Y, Meng Q, Liu Q, Liu Z, et al. Catalpol Inhibits Homocysteine-induced Oxidation and Inflammation via Inhibiting Nox4/NF-κB and GRP78/PERK Pathways in Human Aorta Endothelial Cells. Inflammation. 2019;42:64-80 pubmed 出版商
Choi S, Kim Y, Park Y, Yang H, Jeong P, Cha J, et al. Novel crosstalk between Vps26a and Nox4 signaling during neurogenesis. Cell Death Differ. 2018;: pubmed 出版商
Jiang H, Gao X, Gong J, Yang Q, Lan R, Wang T, et al. Downregulated Expression of Solute Carrier Family 26 Member 6 in NRK-52E Cells Attenuates Oxalate-Induced Intracellular Oxidative Stress. Oxid Med Cell Longev. 2018;2018:1724648 pubmed 出版商
Fan L, Xiao Q, Zhang L, Wang X, Huang Q, Li S, et al. CAPE-pNO2 attenuates diabetic cardiomyopathy through the NOX4/NF-κB pathway in STZ-induced diabetic mice. Biomed Pharmacother. 2018;108:1640-1650 pubmed 出版商
Li Z, Zhang X, Liu S, Zeng S, Yu L, Yang G, et al. BRG1 regulates NOX gene transcription in endothelial cells and contributes to cardiac ischemia-reperfusion injury. Biochim Biophys Acta Mol Basis Dis. 2018;1864:3477-3486 pubmed 出版商
Takashina Y, Manabe A, Hasegawa H, Matsunaga T, Endo S, Ikari A. Sodium Citrate Increases Expression and Flux of Mg2+ Transport Carriers Mediated by Activation of MEK/ERK/c-Fos Pathway in Renal Tubular Epithelial Cells. Nutrients. 2018;10: pubmed 出版商
Rong Y, Cao B, Liu B, Li W, Chen Y, Chen H, et al. A novel Gallic acid derivative attenuates BLM-induced pulmonary fibrosis in mice. Int Immunopharmacol. 2018;64:183-191 pubmed 出版商
Zhang Y, Li Q, Fang M, Ma Y, Liu N, Yan X, et al. The Kidney Injury Induced by Short-Term PM2.5 Exposure and the Prophylactic Treatment of Essential Oils in BALB/c Mice. Oxid Med Cell Longev. 2018;2018:9098627 pubmed 出版商
Yu L, Yang G, Zhang X, Wang P, Weng X, Yang Y, et al. Megakaryocytic Leukemia 1 Bridges Epigenetic Activation of NADPH Oxidase in Macrophages to Cardiac Ischemia-Reperfusion Injury. Circulation. 2018;138:2820-2836 pubmed 出版商
Shen D, Tian L, Shen T, Sun H, Liu P. Alpha-Lipoic Acid Protects Human Aortic Endothelial Cells Against H2O2-Induced Injury and Inhibits Atherosclerosis in Ovariectomized Low Density Lipoprotein Receptor Knock-Out Mice. Cell Physiol Biochem. 2018;47:2261-2277 pubmed 出版商
Liu L, Hong W, Li M, Ren H, Wang J, Xu H, et al. A Cross Talk Between BRG1 and Males Absent on the First Contributes to Reactive Oxygen Species Production in a Mouse Model of Nonalcoholic Steatohepatitis. Antioxid Redox Signal. 2018;: pubmed 出版商
Liu L, Wu X, Xu H, Yu L, Zhang X, Li L, et al. Myocardin-related transcription factor A (MRTF-A) contributes to acute kidney injury by regulating macrophage ROS production. Biochim Biophys Acta Mol Basis Dis. 2018;1864:3109-3121 pubmed 出版商
Long W, Zhang G, Dong Y, Li D. Dark tea extract mitigates hematopoietic radiation injury with antioxidative activity. J Radiat Res. 2018;59:387-394 pubmed 出版商
Yan J, Wang C, Jin Y, Meng Q, Liu Q, Liu Z, et al. Catalpol ameliorates hepatic insulin resistance in type 2 diabetes through acting on AMPK/NOX4/PI3K/AKT pathway. Pharmacol Res. 2018;130:466-480 pubmed 出版商
Almajdoob S, Hossain E, Anand Srivastava M. Resveratrol attenuates hyperproliferation of vascular smooth muscle cells from spontaneously hypertensive rats: Role of ROS and ROS-mediated cell signaling. Vascul Pharmacol. 2018;101:48-56 pubmed 出版商
Ren T, Wang J, Zhang H, Yuan P, Zhu J, Wu Y, et al. MCUR1-Mediated Mitochondrial Calcium Signaling Facilitates Cell Survival of Hepatocellular Carcinoma via Reactive Oxygen Species-Dependent P53 Degradation. Antioxid Redox Signal. 2018;28:1120-1136 pubmed 出版商
Ma Z, Li Y, Li W, Yan X, Yang G, Zhang J, et al. Nephroprotective Effects of Saponins from Leaves of Panax quinquefolius against Cisplatin-Induced Acute Kidney Injury. Int J Mol Sci. 2017;18: pubmed 出版商
Zhang Q, Wang Z, Sun D, Wang Y, Xu P, Wu W, et al. Novel Therapeutic Effects of Leonurine On Ischemic Stroke: New Mechanisms of BBB Integrity. Oxid Med Cell Longev. 2017;2017:7150376 pubmed 出版商
Lajko M, Cardona H, Taylor J, Farrow K, Fawzi A. Photoreceptor oxidative stress in hyperoxia-induced proliferative retinopathy accelerates rd8 degeneration. PLoS ONE. 2017;12:e0180384 pubmed 出版商
Tsubouchi K, Araya J, Minagawa S, Hara H, Ichikawa A, Saito N, et al. Azithromycin attenuates myofibroblast differentiation and lung fibrosis development through proteasomal degradation of NOX4. Autophagy. 2017;13:1420-1434 pubmed 出版商
Lu S, Wang C, Jin Y, Meng Q, Liu Q, Liu Z, et al. The osteogenesis-promoting effects of alpha-lipoic acid against glucocorticoid-induced osteoporosis through the NOX4, NF-kappaB, JNK and PI3K/AKT pathways. Sci Rep. 2017;7:3331 pubmed 出版商
Yao M, Gao F, Wang X, Shi Y, Liu S, Duan H. Nox4 is involved in high glucose-induced apoptosis in renal tubular epithelial cells via Notch pathway. Mol Med Rep. 2017;15:4319-4325 pubmed 出版商
Zhang D, Liu B, Cao B, Wei F, Yu X, Li G, et al. Synergistic protection of Schizandrin B and Glycyrrhizic acid against bleomycin-induced pulmonary fibrosis by inhibiting TGF-β1/Smad2 pathways and overexpression of NOX4. Int Immunopharmacol. 2017;48:67-75 pubmed 出版商
Chu P, Han G, Ahsan A, Sun Z, Liu S, Zhang Z, et al. Phosphocreatine protects endothelial cells from Methylglyoxal induced oxidative stress and apoptosis via the regulation of PI3K/Akt/eNOS and NF-?B pathway. Vascul Pharmacol. 2017;91:26-35 pubmed 出版商
Zhang J, An S, Fu J, Liu P, Shao T, Li M, et al. Mixed Aqueous Extract of Salvia Miltiorrhiza Reduces Blood Pressure through Inhibition of Vascular Remodelling and Oxidative Stress in Spontaneously Hypertensive Rats. Cell Physiol Biochem. 2016;40:347-360 pubmed
Xiao L, Dong J, Jin S, Xue H, Guo Q, Teng X, et al. Hydrogen Sulfide Improves Endothelial Dysfunction via Downregulating BMP4/COX-2 Pathway in Rats with Hypertension. Oxid Med Cell Longev. 2016;2016:8128957 pubmed 出版商
Liu B, Cao B, Zhang D, Xiao N, Chen H, Li G, et al. Salvianolic acid B protects against paraquat-induced pulmonary injury by mediating Nrf2/Nox4 redox balance and TGF-?1/Smad3 signaling. Toxicol Appl Pharmacol. 2016;309:111-20 pubmed 出版商
Li D, Tian Z, Tang W, Zhang J, Lu L, Sun Z, et al. The Protective Effects of 5-Methoxytryptamine-?-lipoic Acid on Ionizing Radiation-Induced Hematopoietic Injury. Int J Mol Sci. 2016;17: pubmed 出版商
Xu G, Wu H, Zhang J, Li D, Wang Y, Wang Y, et al. Metformin ameliorates ionizing irradiation-induced long-term hematopoietic stem cell injury in mice. Free Radic Biol Med. 2015;87:15-25 pubmed 出版商
Wang J, Shao M, Liu M, Peng P, Li L, Wu W, et al. PKCα promotes generation of reactive oxygen species via DUOX2 in hepatocellular carcinoma. Biochem Biophys Res Commun. 2015;463:839-45 pubmed 出版商
Li Y, Wang W, Xu X, Sun S, Xu X, Qu X. {2-[1-(3-Methoxycarbonylmethyl-1H-indol-2-yl)-1-methyl-ethyl]-1H-indol-3-yl}-acetic Acid Methyl Ester Inhibited Hepatocellular Carcinoma Growth in Bel-7402 Cells and Its Resistant Variants by Activation of NOX4 and SIRT3. Biomed Res Int. 2015;2015:491205 pubmed 出版商
Kim H, Magesh V, Lee J, Kim S, Knaus U, Lee K. Ubiquitin C-terminal hydrolase-L1 increases cancer cell invasion by modulating hydrogen peroxide generated via NADPH oxidase 4. Oncotarget. 2015;6:16287-303 pubmed
Xue H, Zhou S, Xiao L, Guo Q, Liu S, Wu Y. Hydrogen sulfide improves the endothelial dysfunction in renovascular hypertensive rats. Physiol Res. 2015;64:663-72 pubmed
Fu C, Xu D, Wang C, Jin Y, Liu Q, Meng Q, et al. Alpha-Lipoic Acid Promotes Osteoblastic Formation in H2O2 -Treated MC3T3-E1 Cells and Prevents Bone Loss in Ovariectomized Rats. J Cell Physiol. 2015;230:2184-201 pubmed 出版商
Jin Y, Liu K, Peng J, Wang C, Kang L, Chang N, et al. Rhizoma Dioscoreae Nipponicae polysaccharides protect HUVECs from H2O2-induced injury by regulating PPARγ factor and the NADPH oxidase/ROS-NF-κB signal pathway. Toxicol Lett. 2015;232:149-58 pubmed 出版商
图像
图像 1 :
武汉三鹰 14347-1-AP 图像 1
The NOX4 antibody from Proteintech is a rabbit polyclonal antibody to a recombinant protein of human NOX4. This antibody recognizes human, mouse antigen. The NOX4 antibody has been validated for the following applications: FC, IF, IHC, IP, WB, ELISA analysis.
产品信息
目录号 :
14347-1-AP
AntigenName :
NOX4
Package :
150UL
价格 :
299美元
Exsists20ul :
20ul trial size available
FullName :
NADPH氧化酶4
免疫原 :
重组蛋白
物种 :
人类, 小鼠, 大鼠
宿主 :
IsConjugated :
未共轭
AntigenSpecies :
人类
应用 :
免疫印迹, 免疫沉淀, 免疫组化, IF, FC, CoIP, 酶联免疫吸附测定
Clonlity :
多克隆
抗体亚型 :
IgG
同义词 :
Kidney oxidase 1, KOX, KOX 1, NADPH oxidase 4, NOX4, Renal NAD(P)H oxidase, RENOX
PrimaryOrSecondary :
Primary
抗体缓冲液 :
PBS with 0.02% sodium azide and 50% glycerol pH 7.3.
GenBank登录号 :
BC040105
类别 :
Binding Proteins;Cell Cycle;Cytoskeleton/Scaffold Proteins;Immunology;Membrane Proteins;Metabolism;Transport/Trafficking;
PurifyMethod :
抗原亲和纯化
NewAb :
False
IsSellable :
True
Feature :
siRNA
AppTiter :
FC 1:0;IF 1:25;免疫组化1:200;免疫沉淀1:1000;免疫印迹1:2000;
更多信息或购买 :
公司信息
武汉三鹰
武汉市洪山区关山二路关东科技园7-4#,402室
Service@ptglab.com
http://www.ptgcn.com
4006 900 926, 027-87531629 / 027-87531627
公司总部: 美国
Proteintech Group致力于开发针对所有人类蛋白的抗体,我们将这项计划命名为人类抗体组计划。Proteintech Group在科研领域享有良好声誉, 迄今已生产出针对10,000种不同人类蛋白的10,000种抗体。同时,Proteintech Group也提供多种客户订单服务:克隆,表达,多肽合成,多抗及单抗生产,以满足您的不同需求。

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我们承诺为您提供高品质的抗体及相关产品,让您不再担忧试剂的品质,让您能够倾注您全部的创造力,才华和精力于研究当中。我们坚信只有您成功了,我们才会成功。