产品简要
公司名称 :
武汉三鹰
产品类型 :
抗体
产品名称 :
LC3
目录 :
14600-1-AP
规格 :
150UL
价格 :
299美元
克隆性 :
多克隆
宿主 :
domestic rabbit
共轭标签 :
未共轭
反应物种 :
人类, 小鼠
应用 :
免疫印迹, 酶联免疫吸附测定, 免疫组化, 免疫细胞化学, 免疫沉淀, 流式细胞仪
更多信息或购买 :
文章摘录数: 158
出版应用/物种/样本/稀释参考文献
  • 免疫印迹; 小鼠; 图 5b
Xiang S, Chen K, Xu L, Wang T, Guo C. Bergenin Exerts Hepatoprotective Effects by Inhibiting the Release of Inflammatory Factors, Apoptosis and Autophagy via the PPAR-γ Pathway. Drug Des Devel Ther. 2020;14:129-143 pubmed 出版商
  • 免疫印迹; 小鼠; 1:1000; 图 2e
Zhou Q, Zhu L, Qiu W, Liu Y, Yang F, Chen W, et al. Nicotinamide Riboside Enhances Mitochondrial Proteostasis and Adult Neurogenesis through Activation of Mitochondrial Unfolded Protein Response Signaling in the Brain of ALS SOD1G93A Mice. Int J Biol Sci. 2020;16:284-297 pubmed 出版商
  • 免疫印迹; 人类; 图 3d
Park S, Choi Y, Jung N, Kim J, Oh S, Yu Y, et al. Autophagy induction in the skeletal myogenic differentiation of human tonsil-derived mesenchymal stem cells. Int J Mol Med. 2017;39:831-840 pubmed 出版商
Jin C, Miao X, Zhong Y, Han J, Liu Q, Zhu J, et al. The renoprotective effect of diosgenin on aristolochic acid I-induced renal injury in rats: impact on apoptosis, mitochondrial dynamics and autophagy. Food Funct. 2020;: pubmed 出版商
Li Z, Cheng J, Liu J. Baicalin Protects Human OA Chondrocytes Against IL-1β-Induced Apoptosis and ECM Degradation by Activating Autophagy via MiR-766-3p/AIFM1 Axis. Drug Des Devel Ther. 2020;14:2645-2655 pubmed 出版商
Liu Z, Ye S, Zhong X, Wang W, Lai C, Yang W, et al. Pretreatment with the ALDH2 activator Alda‑1 protects rat livers from ischemia/reperfusion injury by inducing autophagy. Mol Med Rep. 2020;22:2373-2385 pubmed 出版商
Lu J, Lu J, Chen Y, Feng Z, Liu S, Guan S. 3-Chloro-1, 2-propanediol inhibits autophagic flux by impairment of lysosomal function in HepG2 cells. Food Chem Toxicol. 2020;144:111575 pubmed 出版商
Xu Z, Feng J, Li Y, Guan D, Chen H, Zhai X, et al. The vicious cycle between ferritinophagy and ROS production triggered EMT inhibition of gastric cancer cells was through p53/AKT/mTor pathway. Chem Biol Interact. 2020;328:109196 pubmed 出版商
Yang Y, Liao Y, Gui Y, Zhao L, Guo L. GL-V9 reverses adriamycin resistance in hepatocellular carcinoma cells by affecting JNK2-related autophagy. Chin J Nat Med. 2020;18:491-499 pubmed 出版商
Liu J, Hu Y, Feng Y, Jiang Y, Guo Y, Liu Y, et al. BDH2 triggers ROS-induced cell death and autophagy by promoting Nrf2 ubiquitination in gastric cancer. J Exp Clin Cancer Res. 2020;39:123 pubmed 出版商
Wang L, Xu X, Liu T, Wang J, Shen J, Guo M, et al. 1-(4-((5-chloro-4-((2-(isopropylsulfonyl)phenyl)amino)pyrimidin-2-yl)amino)-3-methoxyphenyl)-3-(2-(dimethylamino)ethyl)imidazolidin-2-one (ZX-42), a novel ALK inhibitor, induces apoptosis and protective autophagy in H2228 cells. J Pharm Pharmacol. 2020;72:1370-1382 pubmed 出版商
Wu B, Jiang M, Liu X, Huang C, Gu Z, Cao Y. Evaluation of toxicity of halloysite nanotubes and multi-walled carbon nanotubes to endothelial cells in vitro and blood vessels in vivo. Nanotoxicology. 2020;:1-22 pubmed 出版商
Xu J, Zhang M, Lin X, Wang Y, He X. A steroidal saponin isolated from Allium chinense simultaneously induces apoptosis and autophagy by modulating the PI3K/Akt/mTOR signaling pathway in human gastric adenocarcinoma. Steroids. 2020;161:108672 pubmed 出版商
Reimann L, Schwäble A, Fricke A, Mühlhäuser W, Leber Y, Lohanadan K, et al. Phosphoproteomics identifies dual-site phosphorylation in an extended basophilic motif regulating FILIP1-mediated degradation of filamin-C. Commun Biol. 2020;3:253 pubmed 出版商
You L, Chen J, Liu W, Xiang Q, Luo Z, Wang W, et al. Enterovirus 71 induces neural cell apoptosis and autophagy through promoting ACOX1 downregulation and ROS generation. Virulence. 2020;11:537-553 pubmed 出版商
Huang Y, Wang Y, Meng S, Chen Z, Kong H, Pan T, et al. Autophagy Contributes to Host Immunity and Protection against Zika Virus Infection via Type I IFN Signaling. Mediators Inflamm. 2020;2020:9527147 pubmed 出版商
Ma J, Qi J, Li S, Zhang C, Wang H, Shao L, et al. Desloratadine, a Novel Antigrowth Reagent for Bladder Cancer. Technol Cancer Res Treat. 2020;19:1533033820926591 pubmed 出版商
Jiang W, Zhao W, Ye F, Huang S, Wu Y, Chen H, et al. Inhibiting PKCβ2 protects HK-2 cells against meglumine diatrizoate and AGEs-induced apoptosis and autophagy. Ann Transl Med. 2020;8:293 pubmed 出版商
Ji J, Wu L, Feng J, Mo W, Wu J, Yu Q, et al. Cafestol preconditioning attenuates apoptosis and autophagy during hepatic ischemia-reperfusion injury by inhibiting ERK/PPARγ pathway. Int Immunopharmacol. 2020;84:106529 pubmed 出版商
Chen H, Liang F, Gu P, Xu B, Xu H, Wang W, et al. Exosomes derived from mesenchymal stem cells repair a Parkinson's disease model by inducing autophagy. Cell Death Dis. 2020;11:288 pubmed 出版商
Li S, Hao M, Li B, Chen M, Chen J, Tang J, et al. CACNA1H downregulation induces skeletal muscle atrophy involving endoplasmic reticulum stress activation and autophagy flux blockade. Cell Death Dis. 2020;11:279 pubmed 出版商
Dai L, Yu Q, Zhou S, Bao Y, Zhong J, Shen L, et al. Effect of combination of curcumin and GLUT-1 AS-ODN on radiosensitivity of laryngeal carcinoma through regulating autophagy. Head Neck. 2020;42:2287-2297 pubmed 出版商
Yao X, Jiang H, Gao Q, Li Y, Xu Y, Kim N. Melatonin alleviates defects induced by zearalenone during porcine embryo development. Theriogenology. 2020;151:66-73 pubmed 出版商
Xie X, Chen C, Xu C, Lin J, Cao L, Chen G, et al. The Class III PI3K/Beclin-1 Autophagic Pathway Participates in the mmLDL-Induced Upregulation of ETA Receptor in Mouse Mesenteric Arteries. Adv Pharmacol Pharm Sci. 2020;2020:5070436 pubmed 出版商
Sun Y, Lu F, Yu X, Wang B, Chen J, Lu F, et al. Exogenous H2S Promoted USP8 Sulfhydration to Regulate Mitophagy in the Hearts of db/db Mice. Aging Dis. 2020;11:269-285 pubmed 出版商
Feng J, Li C, Xu R, Li Y, Hou Q, Feng R, et al. DpdtC-Induced EMT Inhibition in MGC-803 Cells Was Partly through Ferritinophagy-Mediated ROS/p53 Pathway. Oxid Med Cell Longev. 2020;2020:9762390 pubmed 出版商
Hu Y, Chen H, Zhang L, Lin X, Li X, Zhuang H, et al. The AMPK-MFN2 axis regulates MAM dynamics and autophagy induced by energy stresses. Autophagy. 2020;:1-15 pubmed 出版商
Gu L, Li Q, Liu H, Lu X, Zhu M. Long Noncoding RNA TUG1 Promotes Autophagy-Associated Paclitaxel Resistance by Sponging miR-29b-3p in Ovarian Cancer Cells. Onco Targets Ther. 2020;13:2007-2019 pubmed 出版商
Sun X, Wang D, Zhang T, Lu X, Duan F, Ju L, et al. Eugenol Attenuates Cerebral Ischemia-Reperfusion Injury by Enhancing Autophagy via AMPK-mTOR-P70S6K Pathway. Front Pharmacol. 2020;11:84 pubmed 出版商
Tan Y, Yin L, Sun Z, Shao S, Chen W, Man X, et al. Astragalus polysaccharide exerts anti-Parkinson via activating the PI3K/AKT/mTOR pathway to increase cellular autophagy level in vitro. Int J Biol Macromol. 2020;153:349-356 pubmed 出版商
Wang N, Xu F, Lu S, Zhang N, Sun Y. Septin4 as an autophagy modulator regulates Angiotensin-II mediated VSMCs proliferation and migration. Biochem Biophys Res Commun. 2020;525:272-279 pubmed 出版商
Liang C, Feng Z, Manthari R, Wang C, Han Y, Fu W, et al. Arsenic induces dysfunctional autophagy via dual regulation of mTOR pathway and Beclin1-Vps34/PI3K complex in MLTC-1 cells. J Hazard Mater. 2020;391:122227 pubmed 出版商
Shang Y, Wang Q, Li J, Zhao Q, Huang X, Dong H, et al. The Acetone Indigo Red Dehydrating Agent IF203 Induces HepG2 Cell Death Through Cell Cycle Arrest, Autophagy and Apoptosis. Onco Targets Ther. 2020;13:473-486 pubmed 出版商
Yu M, Zeng M, Pan Z, Wu F, Guo L, He G. Discovery of novel akt1 inhibitor induces autophagy associated death in hepatocellular carcinoma cells. Eur J Med Chem. 2020;189:112076 pubmed 出版商
Liu Y, Fan D. The Preparation of Ginsenoside Rg5, Its Antitumor Activity against Breast Cancer Cells and Its Targeting of PI3K. Nutrients. 2020;12: pubmed 出版商
Xu J, Deng Y, Wang Y, Sun X, Chen S, Fu G. SPAG5-AS1 inhibited autophagy and aggravated apoptosis of podocytes via SPAG5/AKT/mTOR pathway. Cell Prolif. 2020;53:e12738 pubmed 出版商
Hu Z, Pan Y, Cheng A, Zhang X, Wang M, Chen S, et al. Autophagy Promotes Duck Tembusu Virus Replication by Suppressing p62/SQSTM1-Mediated Innate Immune Responses In Vitro. Vaccines (Basel). 2020;8: pubmed 出版商
Wang M, Yang C, Jin Y, Wan C, Qian W, Xing F, et al. Baicalin Inhibits Coxsackievirus B3 Replication by Reducing Cellular Lipid Synthesis. Am J Chin Med. 2020;:1-18 pubmed 出版商
Liu Q, Zhao M, Chen W, Xu K, Huang F, Qu J, et al. Mainstream cigarette smoke induces autophagy and promotes apoptosis in oral mucosal epithelial cells. Arch Oral Biol. 2020;111:104646 pubmed 出版商
Rosencrans W, Walsh Z, Houerbi N, Blum A, Belew M, Liu C, et al. Cells deficient for Krüppel-like factor 4 exhibit mitochondrial dysfunction and impaired mitophagy. Eur J Cell Biol. 2020;99:151061 pubmed 出版商
Baldini F, Portincasa P, Grasselli E, Damonte G, Salis A, Bonomo M, et al. Aquaporin-9 is involved in the lipid-lowering activity of the nutraceutical silybin on hepatocytes through modulation of autophagy and lipid droplets composition. Biochim Biophys Acta Mol Cell Biol Lipids. 2020;1865:158586 pubmed 出版商
Hu L, Wang J, Chen X, Yan Y. Lanosterol modulates proteostasis via dissolving cytosolic sequestosomes/aggresome-like induced structures. Biochim Biophys Acta Mol Cell Res. 2020;1867:118617 pubmed 出版商
Zhang W, Zhu T, Chen L, Luo W, Chao J. MCP-1 mediates ischemia-reperfusion-induced cardiomyocyte apoptosis via MCPIP1 and CaSR. Am J Physiol Heart Circ Physiol. 2020;318:H59-H71 pubmed 出版商
Tang Y, Zhang Y, Liu S, Sun Z, Wang C, Li L, et al. 14-3-3ζ binds to and stabilizes phospho-beclin 1S295 and induces autophagy in hepatocellular carcinoma cells. J Cell Mol Med. 2020;24:954-964 pubmed 出版商
Li X, Ma R, Li Q, Li S, Zhang H, Xie J, et al. Transmembrane Protein 39A Promotes the Replication of Encephalomyocarditis Virus via Autophagy Pathway. Front Microbiol. 2019;10:2680 pubmed 出版商
Ma K, Guo J, Wang G, Ni Q, Liu X. Toll-Like Receptor 2-Mediated Autophagy Promotes Microglial Cell Death by Modulating the Microglial M1/M2 Phenotype. Inflammation. 2019;: pubmed 出版商
Wang L, Huang W, Zhan J. Grape Seed Proanthocyanidins Induce Autophagy and Modulate Survivin in HepG2 Cells and Inhibit Xenograft Tumor Growth in Vivo. Nutrients. 2019;11: pubmed 出版商
Wu X, Jia R, Wang M, Chen S, Liu M, Zhu D, et al. Downregulation of microRNA-30a-5p contributes to the replication of duck enteritis virus by regulating Beclin-1-mediated autophagy. Virol J. 2019;16:144 pubmed 出版商
Wang H, Peng X, Huang Y, Xiao Y, Wang Z, Zhan L. Propofol Attenuates Hypoxia/Reoxygenation-Induced Apoptosis and Autophagy in HK-2 Cells by Inhibiting JNK Activation. Yonsei Med J. 2019;60:1195-1202 pubmed 出版商
Xiao Y, Wei R, Yuan Z, Lan X, Kuang J, Hu D, et al. Rutin suppresses FNDC1 expression in bone marrow mesenchymal stem cells to inhibit postmenopausal osteoporosis. Am J Transl Res. 2019;11:6680-6690 pubmed
Kuang M, Li L, Li C, Wang G. Protective effects of UFL1 against endoplasmic reticulum stress-induced autophagy in bovine mammary epithelial cells. Cell Stress Chaperones. 2019;24:1115-1125 pubmed 出版商
Wang D, Guo H, Yang H, Wang D, Gao P, Wei W. Pterostilbene, An Active Constituent of Blueberries, Suppresses Proliferation Potential of Human Cholangiocarcinoma via Enhancing the Autophagic Flux. Front Pharmacol. 2019;10:1238 pubmed 出版商
Guo X, Shi Y, Du P, Wang J, Han Y, Sun B, et al. HMGB1/TLR4 promotes apoptosis and reduces autophagy of hippocampal neurons in diabetes combined with OSA. Life Sci. 2019;239:117020 pubmed 出版商
Liu J, Hu Y, Feng Y, Guo Y, Liu Y, Yang J, et al. Rafoxanide promotes apoptosis and autophagy of gastric cancer cells by suppressing PI3K /Akt/mTOR pathway. Exp Cell Res. 2019;385:111691 pubmed 出版商
Nazarinia D, Aboutaleb N, Gholamzadeh R, Nasseri Maleki S, Mokhtari B, Nikougoftar M. Conditioned medium obtained from human amniotic mesenchymal stem cells attenuates focal cerebral ischemia/reperfusion injury in rats by targeting mTOR pathway. J Chem Neuroanat. 2019;102:101707 pubmed 出版商
Peng F, Zhang N, Wang C, Wang X, Huang W, Peng C, et al. Aconitine induces cardiomyocyte damage by mitigating BNIP3-dependent mitophagy and the TNFα-NLRP3 signalling axis. Cell Prolif. 2019;:e12701 pubmed 出版商
Wang N, Yang B, Muhetaer G, Wang S, Zheng Y, Lu J, et al. XIAOPI formula promotes breast cancer chemosensitivity via inhibiting CXCL1/HMGB1-mediated autophagy. Biomed Pharmacother. 2019;120:109519 pubmed 出版商
Chan K, Wong E, Wong I, Cheung C, Wong O, Ngan H, et al. Overexpression of iASPP is required for autophagy in response to oxidative stress in choriocarcinoma. BMC Cancer. 2019;19:953 pubmed 出版商
Pian L, Huang X, Zhao M, Zhang Y, Qin C, Zhang J, et al. Leucine-rich repeat and sterile alpha motif containing 1 promotes the oncogenic growth of human hepatocellular carcinoma cells. Cancer Cell Int. 2019;19:255 pubmed 出版商
Bu T, Wang C, Jin H, Meng Q, Huo X, Sun H, et al. Organic anion transporters and PI3K-AKT-mTOR pathway mediate the synergistic anticancer effect of pemetrexed and rhein. J Cell Physiol. 2019;: pubmed 出版商
Wang R, Liu H, Shao Y, Wang K, Yin S, Qiu Y, et al. Sophoridine Inhibits Human Colorectal Cancer Progression via Targeting MAPKAPK2. Mol Cancer Res. 2019;17:2469-2479 pubmed 出版商
Huo T, Jia Y, Yin C, Luo X, Zhao J, Wang Z, et al. Iron dysregulation in vascular dementia: Focused on the AMPK/autophagy pathway. Brain Res Bull. 2019;153:305-313 pubmed 出版商
Xu B, Lang L, Li S, Yuan J, Wang J, Yang H, et al. Corticosterone Excess-Mediated Mitochondrial Damage Induces Hippocampal Neuronal Autophagy in Mice Following Cold Exposure. Animals (Basel). 2019;9: pubmed 出版商
Liu N, Feng J, Lu X, Yao Z, Liu Q, Lv Y, et al. Isorhamnetin Inhibits Liver Fibrosis by Reducing Autophagy and Inhibiting Extracellular Matrix Formation via the TGF-β1/Smad3 and TGF-β1/p38 MAPK Pathways. Mediators Inflamm. 2019;2019:6175091 pubmed 出版商
Ma Z, Zhang J, Xu X, Qu Y, Dong H, Dang J, et al. LncRNA expression profile during autophagy and Malat1 function in macrophages. PLoS ONE. 2019;14:e0221104 pubmed 出版商
Wang F, Lei X, Zhao Y, Yu Q, Li Q, Zhao H, et al. Protective role of thymoquinone in sepsis-induced liver injury in BALB/c mice. Exp Ther Med. 2019;18:1985-1992 pubmed 出版商
Wei W, Lu M, Lan X, Liu N, Wang H, Du J, et al. Neuroprotective effect of Verbascoside on hypoxic-ischemic brain damage in neonatal rat. Neurosci Lett. 2019;711:134415 pubmed 出版商
Gao L, Wang Z, Lu D, Huang J, Liu J, Hong L. Paeonol induces cytoprotective autophagy via blocking the Akt/mTOR pathway in ovarian cancer cells. Cell Death Dis. 2019;10:609 pubmed 出版商
Cali C, Patino M, Tai Y, Ho W, McLean C, Morris C, et al. C9orf72 intermediate repeats are associated with corticobasal degeneration, increased C9orf72 expression and disruption of autophagy. Acta Neuropathol. 2019;: pubmed 出版商
Zhang X, Bu H, Jiang Y, Sun G, Jiang R, Huang X, et al. The antidepressant effects of apigenin are associated with the promotion of autophagy via the mTOR/AMPK/ULK1 pathway. Mol Med Rep. 2019;20:2867-2874 pubmed 出版商
Sun Y, Li C, Feng J, Li Y, Zhai X, Zhang L, et al. Ferritinophagic Flux Activation in CT26 Cells Contributed to EMT Inhibition Induced by a Novel Iron Chelator, DpdtpA. Oxid Med Cell Longev. 2019;2019:8753413 pubmed 出版商
Wang W, Wu L, Li J, Ji J, Chen K, Yu Q, et al. Alleviation of Hepatic Ischemia Reperfusion Injury by Oleanolic Acid Pretreating via Reducing HMGB1 Release and Inhibiting Apoptosis and Autophagy. Mediators Inflamm. 2019;2019:3240713 pubmed 出版商
Wang H, Zhong P, Sun L. Exogenous hydrogen sulfide mitigates NLRP3 inflammasome-mediated inflammation through promoting autophagy via the AMPK-mTOR pathway. Biol Open. 2019;8: pubmed 出版商
Fan Y, Li N, Liu C, Dong H, Hu X. Excessive Methionine Supplementation Exacerbates the Development of Abdominal Aortic Aneurysm in Rats. J Vasc Res. 2019;:1-11 pubmed 出版商
Shang Y, Wang Q, Wu B, Zhao Q, Li J, Huang X, et al. Platelet-Membrane-Camouflaged Black Phosphorus Quantum Dots Enhance Anticancer Effect Mediated by Apoptosis and Autophagy. ACS Appl Mater Interfaces. 2019;11:28254-28266 pubmed 出版商
Li P, Ma R, Dong L, Liu L, Zhou G, Tian Z, et al. Autophagy impairment contributes to PBDE-47-induced developmental neurotoxicity and its relationship with apoptosis. Theranostics. 2019;9:4375-4390 pubmed 出版商
Ye J, Xue M, Liu Y, Zhu S, Li Y, Liu X, et al. Diosbulbin B-Induced Mitochondria-Dependent Apoptosis in L-02 Hepatocytes is Regulated by Reactive Oxygen Species-Mediated Autophagy. Front Pharmacol. 2019;10:676 pubmed 出版商
Zhong W, Shi X, Yuan H, Bu H, Wu L, Wang R. Effects of Exercise Training on the Autophagy-Related Muscular Proteins Expression in Ovariectomized Rats. Front Physiol. 2019;10:735 pubmed 出版商
Zhong Y, Zheng Q, Sun C, Zhang Z, Han K, Jia N. Orientin Improves Cognition by Enhancing Autophagosome Clearance in an Alzheimer's Mouse Model. J Mol Neurosci. 2019;69:246-253 pubmed 出版商
Xu W, Yang R, Zheng H, Yu W, Zheng X, Li B, et al. PGC-1α acts as an mediator of Sirtuin2 to protect annulus fibrosus from apoptosis induced by oxidative stress through restraining mitophagy. Int J Biol Macromol. 2019;136:1007-1017 pubmed 出版商
Liu T, Zong S, Luo P, Yanji Q, Yingying W, Peiyu D, et al. Enhancing autophagy by down-regulating GSK-3β alleviates cisplatin-induced ototoxicity in vivo and in vitro. Toxicol Lett. 2019;: pubmed 出版商
Li N, Guo X, Liu L, Wang L, Cheng R. Molecular mechanism of miR-204 regulates proliferation, apoptosis and autophagy of cervical cancer cells by targeting ATF2. Artif Cells Nanomed Biotechnol. 2019;47:2529-2535 pubmed 出版商
Cui C, Li Z, Wu D. The long non-coding RNA H19 induces hypoxia/reoxygenation injury by up-regulating autophagy in the hepatoma carcinoma cells. Biol Res. 2019;52:32 pubmed 出版商
Ma S, Miao H, Luo Y, Sun Y, Tian X, Wang F, et al. FePt/GO Nanosheets Suppress Proliferation, Enhance Radiosensitization and Induce Autophagy of Human Non-Small Cell Lung Cancer Cells. Int J Biol Sci. 2019;15:999-1009 pubmed 出版商
Zhou G, Tang S, Yang L, Niu Q, Chen J, Xia T, et al. Effects of long-term fluoride exposure on cognitive ability and the underlying mechanisms: Role of autophagy and its association with apoptosis. Toxicol Appl Pharmacol. 2019;:114608 pubmed 出版商
Zhu J, Li J, Wang X, Feng X, Li Y. Nonstructural Protein NP1 of Human Bocavirus 1 suppresses the growth of A549 cell by promoting autophagy. New Microbiol. 2019;42:161-165 pubmed
Wu X, Ansari A, Pang X, Li H, Zhang Z, Luo Y, et al. Visfatin Plays a Significant Role in Alleviating Lipopolysaccharide-Induced Apoptosis and Autophagy Through PI3K/AKT Signaling Pathway During Acute Lung Injury in Mice. Arch Immunol Ther Exp (Warsz). 2019;: pubmed 出版商
Barot S, Abo Ali E, Zhou D, Palaguachi C, Dukhande V. Inhibition of glycogen catabolism induces intrinsic apoptosis and augments multikinase inhibitors in hepatocellular carcinoma cells. Exp Cell Res. 2019;: pubmed 出版商
Liu P, Li Y, Yang W, Liu D, Ji X, Chi T, et al. Prevention of Huntington's Disease-Like Behavioral Deficits in R6/1 Mouse by Tolfenamic Acid Is Associated with Decreases in Mutant Huntingtin and Oxidative Stress. Oxid Med Cell Longev. 2019;2019:4032428 pubmed 出版商
Chen C, Jiang L, Zhang M, Pan X, Peng C, Huang W, et al. Isodunnianol alleviates doxorubicin-induced myocardial injury by activating protective autophagy. Food Funct. 2019;10:2651-2657 pubmed 出版商
Zhou Q, Wang L, Chen H, Xu B, Xu W, Sheng Y, et al. 2,3',4,4',5-Pentachlorobiphenyl induced autophagy of the thyrocytes via DAPK2/PKD/VPS34 pathway. Arch Toxicol. 2019;: pubmed 出版商
Li R, Du J, Yao Y, Yao G, Wang X. Adiponectin inhibits high glucose-induced angiogenesis via inhibiting autophagy in RF/6A cells. J Cell Physiol. 2019;: pubmed 出版商
Xu G, Wang X, Yu H, Wang C, Liu Y, Zhao R, et al. Beclin 1, LC3, and p62 expression in paraquat-induced pulmonary fibrosis. Hum Exp Toxicol. 2019;38:794-802 pubmed 出版商
Yin F, Yan J, Zhao Y, Guo K, Zhang Z, Li A, et al. Bone marrow mesenchymal stem cells repair Cr (VI)- injured kidney by regulating mitochondria-mediated apoptosis and mitophagy mediated via the MAPK signaling pathway. Ecotoxicol Environ Saf. 2019;176:234-241 pubmed 出版商
Wu J, Kuang L, Chen C, Yang J, Zeng W, Li T, et al. miR-100-5p-abundant exosomes derived from infrapatellar fat pad MSCs protect articular cartilage and ameliorate gait abnormalities via inhibition of mTOR in osteoarthritis. Biomaterials. 2019;206:87-100 pubmed 出版商
Du W, Wang N, Li F, Jia K, An J, Liu Y, et al. STAT3 phosphorylation mediates high glucose-impaired cell autophagy in an HDAC1-dependent and -independent manner in Schwann cells of diabetic peripheral neuropathy. FASEB J. 2019;:fj201900127R pubmed 出版商
Yu Q, Wu L, Liu T, Li S, Feng J, Mao Y, et al. Protective effects of levo-tetrahydropalmatine on hepatic ischemia/reperfusion injury are mediated by inhibition of the ERK/NF-κB pathway. Int Immunopharmacol. 2019;70:435-445 pubmed 出版商
Zhang Q, Meng X, Qin G, Xue X, Dang N. Lyn Kinase Promotes the Proliferation of Malignant Melanoma Cells through Inhibition of Apoptosis and Autophagy via the PI3K/Akt Signaling Pathway. J Cancer. 2019;10:1197-1208 pubmed 出版商
Xia Y, Zhang G, Han C, Ma K, Guo X, Wan F, et al. Microglia as modulators of exosomal alpha-synuclein transmission. Cell Death Dis. 2019;10:174 pubmed 出版商
Ma L, Liu Y, Zhao X, Li P, Jin Q. Rapamycin attenuates articular cartilage degeneration by inhibiting β-catenin in a murine model of osteoarthritis. Connect Tissue Res. 2019;:1-11 pubmed 出版商
Li L, Li L, Zhou X, Yu Y, Li Z, Zuo D, et al. Silver nanoparticles induce protective autophagy via Ca2+/CaMKKβ/AMPK/mTOR pathway in SH-SY5Y cells and rat brains. Nanotoxicology. 2019;13:369-391 pubmed 出版商
Nian F, Li L, Cheng C, Wu P, Lin Y, Tang C, et al. Rab18 Collaborates with Rab7 to Modulate Lysosomal and Autophagy Activities in the Nervous System: an Overlapping Mechanism for Warburg Micro Syndrome and Charcot-Marie-Tooth Neuropathy Type 2B. Mol Neurobiol. 2019;: pubmed 出版商
Mao Z, Han X, Chen D, Xu Y, Xu L, Yin L, et al. Potent effects of dioscin against hepatocellular carcinoma through regulating TP53-induced glycolysis and apoptosis regulator (TIGAR)-mediated apoptosis, autophagy, and DNA damage. Br J Pharmacol. 2019;176:919-937 pubmed 出版商
Ho W, Tai Y, Chang J, Liang J, Tyan S, Chen S, et al. The ALS-FTD-linked gene product, C9orf72, regulates neuronal morphogenesis via autophagy. Autophagy. 2019;15:827-842 pubmed 出版商
Ren Z, Xiao W, Zeng Y, Liu M, Li G, Tang Z, et al. Fibroblast growth factor-21 alleviates hypoxia/reoxygenation injury in H9c2 cardiomyocytes by promoting autophagic flux. Int J Mol Med. 2019;43:1321-1330 pubmed 出版商
Zhao Q, Niu Q, Chen J, Xia T, Zhou G, Li P, et al. Roles of mitochondrial fission inhibition in developmental fluoride neurotoxicity: mechanisms of action in vitro and associations with cognition in rats and children. Arch Toxicol. 2019;93:709-726 pubmed 出版商
Wu X, Zhang J, Ma C, Li W, Zeng J, Wang Y, et al. A role for Wnt/β-catenin signalling in suppressing Bacillus Calmette-Guerin-induced macrophage autophagy. Microb Pathog. 2019;127:277-287 pubmed 出版商
Hasnat M, Yuan Z, Naveed M, Khan A, Raza F, Xu D, et al. Drp1-associated mitochondrial dysfunction and mitochondrial autophagy: a novel mechanism in triptolide-induced hepatotoxicity. Cell Biol Toxicol. 2019;35:267-280 pubmed 出版商
Zhang W, He B, Wu Y, Qiao J, Peng Z. Melatonin protects against sepsis-induced cardiac dysfunction by regulating apoptosis and autophagy via activation of SIRT1 in mice. Life Sci. 2019;217:8-15 pubmed 出版商
Li J, Li B, Cheng Y, Meng Q, Wei L, Li W, et al. The synergistic effect of NOD2 and TLR4 on the activation of autophagy in human submandibular gland inflammation. J Oral Pathol Med. 2019;48:87-95 pubmed 出版商
Zhang Z, Zhang M, Liu H, Yin W. AZD9291 promotes autophagy and inhibits PI3K/Akt pathway in NSCLC cancer cells. J Cell Biochem. 2019;120:756-767 pubmed 出版商
Liu T, Xu L, Wang C, Chen K, Xia Y, Li J, et al. Alleviation of hepatic fibrosis and autophagy via inhibition of transforming growth factor-β1/Smads pathway through shikonin. J Gastroenterol Hepatol. 2019;34:263-276 pubmed 出版商
Sun R, Fan Y, Liang X, Gong T, Wang Q, Liu H, et al. Rapamycin and FTY720 Alleviate Atherosclerosis by Cross Talk of Macrophage Polarization and Autophagy. Biomed Res Int. 2018;2018:1010248 pubmed 出版商
Yu Q, Liu T, Li S, Feng J, Wu L, Wang W, et al. The Protective Effects of Levo-Tetrahydropalmatine on ConA-Induced Liver Injury Are via TRAF6/JNK Signaling. Mediators Inflamm. 2018;2018:4032484 pubmed 出版商
Deng J, Feng J, Liu T, Lu X, Wang W, Liu N, et al. Beraprost sodium preconditioning prevents inflammation, apoptosis, and autophagy during hepatic ischemia-reperfusion injury in mice via the P38 and JNK pathways. Drug Des Devel Ther. 2018;12:4067-4082 pubmed 出版商
Hsiao C, Chang C, Ibrahim R, Lin I, Wang C, Wang W, et al. Gli2 modulates cell cycle re-entry through autophagy-mediated regulation of the length of primary cilia. J Cell Sci. 2018;131: pubmed 出版商
Chen T, Huang B, Shi X, Gao L, Huang C. Mutant UBQLN2P497H in motor neurons leads to ALS-like phenotypes and defective autophagy in rats. Acta Neuropathol Commun. 2018;6:122 pubmed 出版商
Wu Y, Li Y, Wu B, Tan C, He X, Xu B, et al. β-Arrestin2 Inhibits Expression of Inflammatory Cytokines in BEAS-2B Lung Epithelial Cells Treated with Cigarette Smoke Condensate via Inhibition of Autophagy. Cell Physiol Biochem. 2018;50:1270-1285 pubmed 出版商
Wu J, Li L, Wang S, Pang X, Wu J, Sheng S, et al. Autophagy is positively associated with the accumulation of myeloid‑derived suppressor cells in 4‑nitroquinoline‑1‑oxide‑induced oral cancer. Oncol Rep. 2018;40:3381-3391 pubmed 出版商
Wu Y, Li Y, Wang B, He X, Li Y, Wu B, et al. Role of p62/SQSTM1 in lipopolysaccharide (LPS)-induced mucus hypersecretion in bronchial epithelial cells. Life Sci. 2018;211:270-278 pubmed 出版商
Li Y, Fu S, Li E, Sun X, Xu H, Meng Y, et al. Modulation of autophagy in the protective effect of resveratrol on PM2.5-induced pulmonary oxidative injury in mice. Phytother Res. 2018;32:2480-2486 pubmed 出版商
Manthari R, Tikka C, Ommati M, Niu R, Sun Z, Wang J, et al. Arsenic induces autophagy in developmental mouse cerebral cortex and hippocampus by inhibiting PI3K/Akt/mTOR signaling pathway: involvement of blood-brain barrier's tight junction proteins. Arch Toxicol. 2018;92:3255-3275 pubmed 出版商
Liu Y, Cao W, Kong X, Li J, Chen X, Ge Y, et al. Protective effects of α‑2‑macroglobulin on human bone marrow mesenchymal stem cells in radiation injury. Mol Med Rep. 2018;18:4219-4228 pubmed 出版商
Liu Y, Fan D. Ginsenoside Rg5 induces apoptosis and autophagy via the inhibition of the PI3K/Akt pathway against breast cancer in a mouse model. Food Funct. 2018;9:5513-5527 pubmed 出版商
Luo L, Lu J, Wang Q, Chen S, Xu A, Yuan S. Autophagy participates in innate immune defense in lamprey. Fish Shellfish Immunol. 2018;83:416-424 pubmed 出版商
Huang T, Sun Y, Li Y, Wang T, Fu Y, Li C, et al. Growth Inhibition of a Novel Iron Chelator, DpdtC, against Hepatoma Carcinoma Cell Lines Partly Attributed to Ferritinophagy-Mediated Lysosomal ROS Generation. Oxid Med Cell Longev. 2018;2018:4928703 pubmed 出版商
Shen X, Jin Y, Liang S, Kwon J, Zhu J, Lei L, et al. Autophagy is required for proper meiosis of porcine oocytes maturing in vitro. Sci Rep. 2018;8:12581 pubmed 出版商
Liu J, Lv X, Dong W, Hu M, Xu J, Qian G, et al. The Role of SIRT1 in Autophagy in Lipopolysaccharide-Induced Mouse Type II Alveolar Epithelial Cells. Inflammation. 2018;41:2222-2235 pubmed 出版商
Shi G, Zheng J, Han X, Jiang Y, Li Z, Wu J, et al. Lycium barbarum polysaccharide attenuates diabetic testicular dysfunction via inhibition of the PI3K/Akt pathway-mediated abnormal autophagy in male mice. Cell Tissue Res. 2018;374:653-666 pubmed 出版商
Guo S, Liang X, Guo M, Zhang X, Li Z. Migration inhibition of water stress proteins from Nostoc commune Vauch. via activation of autophagy in DLD-1 cells. Int J Biol Macromol. 2018;119:669-676 pubmed 出版商
Wang L, Yin Y, Hou G, Kang J, Wang Q. Peroxisome Proliferator-Activated Receptor (PPARγ) Plays a Protective Role in Cigarette Smoking-Induced Inflammation via AMP-Activated Protein Kinase (AMPK) Signaling. Med Sci Monit. 2018;24:5168-5177 pubmed 出版商
Manthari R, Tikka C, Ommati M, Niu R, Sun Z, Wang J, et al. Arsenic-Induced Autophagy in the Developing Mouse Cerebellum: Involvement of the Blood-Brain Barrier's Tight-Junction Proteins and the PI3K-Akt-mTOR Signaling Pathway. J Agric Food Chem. 2018;66:8602-8614 pubmed 出版商
Li P, Liu L, Zhou G, Tian Z, Luo C, Xia T, et al. Perigestational exposure to low doses of PBDE-47 induces excessive ER stress, defective autophagy and the resultant apoptosis contributing to maternal thyroid toxicity. Sci Total Environ. 2018;645:363-371 pubmed 出版商
Zhang W, Xu W, Chen W, Zhou Q. Interplay of Autophagy Inducer Rapamycin and Proteasome Inhibitor MG132 in Reduction of Foam Cell Formation and Inflammatory Cytokine Expression. Cell Transplant. 2018;27:1235-1248 pubmed 出版商
Feng J, Chen K, Xia Y, Wu L, Li J, Li S, et al. Salidroside ameliorates autophagy and activation of hepatic stellate cells in mice via NF-κB and TGF-β1/Smad3 pathways. Drug Des Devel Ther. 2018;12:1837-1853 pubmed 出版商
Yu Z, Ma J, Li X, Liu Y, Li M, Wang L, et al. Autophagy defects and related genetic variations in renal cell carcinoma with eosinophilic cytoplasmic inclusions. Sci Rep. 2018;8:9972 pubmed 出版商
Liu H, Wang L, Zeng Q, Zhao L, Cui Y, Hou C, et al. Oxidative stress-mediated autophagic cell death participates in the neurotoxic effect on SH-SY5Y cells induced by excessive iodide. Environ Toxicol. 2018;: pubmed 出版商
Liu Z, Zhu P, Zhang L, Xiong B, Tao J, Guan W, et al. Autophagy inhibition attenuates the induction of anti-inflammatory effect of catalpol in liver fibrosis. Biomed Pharmacother. 2018;103:1262-1271 pubmed 出版商
Feng J, Niu P, Chen K, Wu L, Liu T, Xu S, et al. Salidroside mediates apoptosis and autophagy inhibition in concanavalin A-induced liver injury. Exp Ther Med. 2018;15:4599-4614 pubmed 出版商
Wang W, Chen K, Xia Y, Mo W, Wang F, Dai W, et al. The Hepatoprotection by Oleanolic Acid Preconditioning: Focusing on PPAR? Activation. PPAR Res. 2018;2018:3180396 pubmed 出版商
Li Y, Qian W, Wang D, Meng Y, Wang X, Chen Y, et al. Resveratrol relieves particulate matter (mean diameter < 2.5 ?m)-induced oxidative injury of lung cells through attenuation of autophagy deregulation. J Appl Toxicol. 2018;38:1251-1261 pubmed 出版商
Ji J, Xue T, Guo X, Yang J, Guo R, Wang J, et al. Antagonizing peroxisome proliferator-activated receptor γ facilitates M1-to-M2 shift of microglia by enhancing autophagy via the LKB1-AMPK signaling pathway. Aging Cell. 2018;17:e12774 pubmed 出版商
Liu Y, Li L, Xu L, Dai E, Chen W. Cantharidin suppresses cell growth and migration, and activates autophagy in human non-small cell lung cancer cells. Oncol Lett. 2018;15:6527-6532 pubmed 出版商
Chan K, Wong O, Wong E, Chan K, Ip P, Tse K, et al. Impact of iASPP on chemoresistance through PLK1 and autophagy in ovarian clear cell carcinoma. Int J Cancer. 2018;143:1456-1469 pubmed 出版商
Wang H, Mao B, Chen C. Xiaoqinglong Decoction Attenuates Chronic Obstructive Pulmonary Disease in Rats via Inhibition of Autophagy. Evid Based Complement Alternat Med. 2018;2018:6705871 pubmed 出版商
Bai Z, Gao M, Xu X, Zhang H, Xu J, Guan Q, et al. Overcoming resistance to mitochondrial apoptosis by BZML-induced mitotic catastrophe is enhanced by inhibition of autophagy in A549/Taxol cells. Cell Prolif. 2018;51:e12450 pubmed 出版商
Chen T, Song G, Yang H, Mao L, Cui Z, Huang K. Development of the Swimbladder Surfactant System and Biogenesis of Lysosome-Related Organelles Is Regulated by BLOS1 in Zebrafish. Genetics. 2018;208:1131-1146 pubmed 出版商
Wei W, An X, Jin S, Li X, Xu M. Inhibition of insulin resistance by PGE1 via autophagy-dependent FGF21 pathway in diabetic nephropathy. Sci Rep. 2018;8:9 pubmed 出版商
Yang L, Han B, Zhang Y, Bai Y, Chao J, Hu G, et al. Engagement of circular RNA HECW2 in the nonautophagic role of ATG5 implicated in the endothelial-mesenchymal transition. Autophagy. 2018;14:404-418 pubmed 出版商
Dai C, Ciccotosto G, Cappai R, Wang Y, Tang S, Hoyer D, et al. Rapamycin Confers Neuroprotection against Colistin-Induced Oxidative Stress, Mitochondria Dysfunction, and Apoptosis through the Activation of Autophagy and mTOR/Akt/CREB Signaling Pathways. ACS Chem Neurosci. 2018;9:824-837 pubmed 出版商
Dun Y, Liu S, Zhang W, Xie M, Qiu L. Exercise Combined with Rhodiola sacra Supplementation Improves Exercise Capacity and Ameliorates Exhaustive Exercise-Induced Muscle Damage through Enhancement of Mitochondrial Quality Control. Oxid Med Cell Longev. 2017;2017:8024857 pubmed 出版商
Yang W, Li L, Huang X, Kan G, Lin L, Cheng J, et al. Levels of Leydig cell autophagy regulate the fertility of male naked mole-rats. Oncotarget. 2017;8:98677-98690 pubmed 出版商
Yang Y, Liu J, Gui Y, Lei L, Zhang S. Relationship between autophagy and perineural invasion, clinicopathological features, and prognosis in pancreatic cancer. World J Gastroenterol. 2017;23:7232-7241 pubmed 出版商
Zhao Z, Zhang L, Guo X, Cao L, Xue T, Zhao X, et al. Rosiglitazone Exerts an Anti-depressive Effect in Unpredictable Chronic Mild-Stress-Induced Depressive Mice by Maintaining Essential Neuron Autophagy and Inhibiting Excessive Astrocytic Apoptosis. Front Mol Neurosci. 2017;10:293 pubmed 出版商
Zhang J, Zhu Y, Shi Y, Han Y, Liang C, Feng Z, et al. Fluoride-Induced Autophagy via the Regulation of Phosphorylation of Mammalian Targets of Rapamycin in Mice Leydig Cells. J Agric Food Chem. 2017;65:8966-8976 pubmed 出版商
Wang K, Li S, Worku T, Hao X, Yang L, Zhang S. Rab11a is required for porcine reproductive and respiratory syndrome virus induced autophagy to promote viral replication. Biochem Biophys Res Commun. 2017;492:236-242 pubmed 出版商
Huang R, Zhang Y, Han B, Bai Y, Zhou R, Gan G, et al. Circular RNA HIPK2 regulates astrocyte activation via cooperation of autophagy and ER stress by targeting MIR124-2HG. Autophagy. 2017;13:1722-1741 pubmed 出版商
Chen T, Ren H, Thakur A, Yang T, Li Y, Zhang S, et al. Decreased Level of Klotho Contributes to Drug Resistance in Lung Cancer Cells: Involving in Klotho-Mediated Cell Autophagy. DNA Cell Biol. 2016;35:751-757 pubmed
图像
图像 1 :
武汉三鹰 14600-1-AP 图像 1
The LC3 antibody from Proteintech is a rabbit polyclonal antibody to a recombinant protein of human LC3. This antibody recognizes human, mouse, rat antigen. The LC3 antibody has been validated for the following applications: FC, IF, IHC, IP, WB, ELISA analysis.
产品信息
目录号 :
14600-1-AP
AntigenName :
LC3
Package :
150UL
价格 :
299美元
Exsists20ul :
20ul trial size available
FullName :
微管相关蛋白1照明链3乙
免疫原 :
重组蛋白
物种 :
cow, duck, goat, human, monkey, mouse, rabbit, rat, swine, zebrafish
宿主 :
IsConjugated :
未共轭
AntigenSpecies :
人类
应用 :
免疫印迹, 免疫沉淀, 免疫组化, IF, FC, 酶联免疫吸附测定
Clonlity :
多克隆
抗体亚型 :
IgG
同义词 :
LC3, LC3B, LC3-II, MAP1A/1BLC3, MAP1A/MAP1B LC3 B, MAP1A/MAP1B照明链3 B, MAP1ALC3, MAP1LC3B
PrimaryOrSecondary :
Primary
抗体缓冲液 :
PBS with 0.02% sodium azide and 50% glycerol pH 7.3.
GenBank登录号 :
BC067797
类别 :
Apoptosis;Autophagy;Binding Proteins;Cytoskeleton/Scaffold Proteins;Membrane Proteins;Metabolism;Neurology;
PurifyMethod :
抗原亲和纯化
NewAb :
False
IsSellable :
True
AppTiter :
FC 1:0;IF 1:400;免疫组化1:600;免疫沉淀1:1000;免疫印迹1:2500;
更多信息或购买 :
公司信息
武汉三鹰
武汉市洪山区关山二路关东科技园7-4#,402室
Service@ptglab.com
http://www.ptgcn.com
4006 900 926, 027-87531629 / 027-87531627
公司总部: 美国
Proteintech Group致力于开发针对所有人类蛋白的抗体,我们将这项计划命名为人类抗体组计划。Proteintech Group在科研领域享有良好声誉, 迄今已生产出针对10,000种不同人类蛋白的10,000种抗体。同时,Proteintech Group也提供多种客户订单服务:克隆,表达,多肽合成,多抗及单抗生产,以满足您的不同需求。

Proteintech Group的创建者都是资深科研人员,我们非常理解科学家们对工作尽善尽美的追求,我们也以同样的标准来要求我们的产品。作为科研领域的成员之一,我们要做每一项科研工作背后的默默支持者,为科学家们提供质量优良,价格合理的产品和服务。

我们承诺为您提供高品质的抗体及相关产品,让您不再担忧试剂的品质,让您能够倾注您全部的创造力,才华和精力于研究当中。我们坚信只有您成功了,我们才会成功。