产品简要
公司名称 :
武汉三鹰
产品类型 :
抗体
产品名称 :
鼠双微基因2
目录 :
19058-1-AP
规格 :
150UL
价格 :
299美元
克隆性 :
多克隆
宿主 :
domestic rabbit
共轭标签 :
未共轭
反应物种 :
人类
应用 :
免疫印迹, 酶联免疫吸附测定, 免疫组化, 免疫细胞化学, 免疫沉淀
更多信息或购买 :
文章摘录数: 35
出版应用/物种/样本/稀释参考文献
  • 免疫印迹; 人类; 1:1000; 图 3e
Wang Q, Jia S, Jiao Y, Xu L, Wang D, Chen X, et al. SSRP1 influences colorectal cancer cell growth and apoptosis via the AKT pathway. Int J Med Sci. 2019;16:1573-1582 pubmed 出版商
  • 免疫印迹; 人类; 1:500
Zhang X, Pan Q, Pan K, Weng D, Wang Q, Zhao J, et al. Expression and prognostic role of ubiquitination factor E4B in primary hepatocellular carcinoma. Mol Carcinog. 2016;55:64-76 pubmed 出版商
Shan B, Zhao R, Zhou J, Zhang M, Qi X, Wang T, et al. AURKA Increase the Chemosensitivity of Colon Cancer Cells to Oxaliplatin by Inhibiting the TP53-Mediated DNA Damage Response Genes. Biomed Res Int. 2020;2020:8916729 pubmed 出版商
Pu X, Zhu L, Li F, Zheng J, Wu H, Fu Y, et al. Target molecular treatment markers in Intrahepatic Cholangiocarcinoma based on Chinese population. Pathol Res Pract. 2020;216:153116 pubmed 出版商
Tong D, Zhang J, Wang X, Li Q, Liu L, Yang J, et al. MeCP2 facilitates breast cancer growth via promoting ubiquitination-mediated P53 degradation by inhibiting RPL5/RPL11 transcription. Oncogenesis. 2020;9:56 pubmed 出版商
Wang Y, Chen J, Li S, Zhang X, Guo Z, Hu J, et al. Exogenous spermine attenuates rat diabetic cardiomyopathy via suppressing ROS-p53 mediated downregulation of calcium-sensitive receptor. Redox Biol. 2020;32:101514 pubmed 出版商
Wang J, Li G, Ming S, Wang C, Shi L, Su B, et al. BRD4 inhibition exerts anti-viral activity through DNA damage-dependent innate immune responses. PLoS Pathog. 2020;16:e1008429 pubmed 出版商
Zhang Y, Cui N, Zheng G. Ubiquitination of P53 by E3 ligase MKRN2 promotes melanoma cell proliferation. Oncol Lett. 2020;19:1975-1984 pubmed 出版商
Zhao Q, Zhu H, Xie X, Mao Q, Liu Y, He X, et al. Novel HSP90-PI3K Dual Inhibitor Suppresses Melanoma Cell Proliferation by Interfering with HSP90-EGFR Interaction and Downstream Signaling Pathways. Int J Mol Sci. 2020;21: pubmed 出版商
Dou Y, Huang D, Zeng X, Zhou Y, Jiang X, Yue C, et al. All-trans retinoic acid enhances the effect of Fra-1 to inhibit cell proliferation and metabolism in cervical cancer. Biotechnol Lett. 2020;42:1051-1060 pubmed 出版商
Liu H, Zhang W, Fang Y, Yang H, Tian L, Li K, et al. Neurotoxicity of aluminum oxide nanoparticles and their mechanistic role in dopaminergic neuron injury involving p53-related pathways. J Hazard Mater. 2020;392:122312 pubmed 出版商
Duan T, Jiao H, He G, Yan Y. Translation Efficiency and Degradation of ER-Associated mRNAs Modulated by ER-Anchored poly(A)-Specific Ribonuclease (PARN). Cells. 2020;9: pubmed 出版商
Liu J, Zhu Z, Liu Y, Wei L, Li B, Mao F, et al. MDM2 inhibition-mediated autophagy contributes to the pro-apoptotic effect of berberine in p53-null leukemic cells. Life Sci. 2020;242:117228 pubmed 出版商
Guo J, Fu W, Xiang M, Zhang Y, Zhou K, Xu C, et al. Notch1 Drives the Formation and Proliferation of Intrahepatic Cholangiocarcinoma. Curr Med Sci. 2019;39:929-937 pubmed 出版商
Li S, Han J, Guo G, Sun Y, Zhang T, Zhao M, et al. Voltage-gated sodium channels β3 subunit promotes tumorigenesis in hepatocellular carcinoma by facilitating p53 degradation. FEBS Lett. 2019;: pubmed 出版商
Wang Z, Li C, Li Y, Guo X, Yan Z, Gao F, et al. DpdtbA-Induced Growth Inhibition in Human Esophageal Cancer Cells Involved Inactivation of the p53/EGFR/AKT Pathway. Oxid Med Cell Longev. 2019;2019:5414670 pubmed 出版商
Fan X, Wang Y, Song J, Wu H, Yang M, Lu L, et al. MDM2 inhibitor RG7388 potently inhibits tumors by activating p53 pathway in nasopharyngeal carcinoma. Cancer Biol Ther. 2019;:1-9 pubmed 出版商
Liang M, Li H, Wang Z, Cai L, Yang L. Rice protein reduces DNA damage by activating the p53 pathway and stimulating endogenous antioxidant response in growing and adult rats. J Sci Food Agric. 2019;: pubmed 出版商
Feng X, Yan N, Sun W, Zheng S, Jiang S, Wang J, et al. miR-4521-FAM129A axial regulation on ccRCC progression through TIMP-1/MMP2/MMP9 and MDM2/p53/Bcl2/Bax pathways. Cell Death Discov. 2019;5:89 pubmed 出版商
Qin F, Wang Y, Jiang X, Wang Y, Zhang N, Wen X, et al. Design, synthesis and molecular mechanisms of novel dual inhibitors of heat shock protein 90/phosphoinositide 3-kinase alpha (Hsp90/PI3Kα) against cutaneous melanoma. J Enzyme Inhib Med Chem. 2019;34:909-926 pubmed 出版商
Fu R, Yang P, Sajid A, Li Z. Avenanthramide A Induces Cellular Senescence via miR-129-3p/Pirh2/p53 Signaling Pathway To Suppress Colon Cancer Growth. J Agric Food Chem. 2019;67:4808-4816 pubmed 出版商
Xie X, Wang X, Liao W, Fei R, Wu N, Cong X, et al. PPPDE1 promotes hepatocellular carcinoma development by negatively regulate p53 and apoptosis. Apoptosis. 2019;24:135-144 pubmed 出版商
Sun Y, Liu W, Wang C, Meng Q, Liu Z, Huo X, et al. Combination of dihydromyricetin and ondansetron strengthens antiproliferative efficiency of adriamycin in K562/ADR through downregulation of SORCIN: A new strategy of inhibiting P-glycoprotein. J Cell Physiol. 2019;234:3685-3696 pubmed 出版商
Liu L, Sun Y, Zhao Y, Wang Q, Guo H, Guo R, et al. Urea transport B gene induces melanoma B16 cell death via activation of p53 and mitochondrial apoptosis. Cancer Sci. 2018;109:3762-3773 pubmed 出版商
Luo Y, Mohsin A, Xu C, Wang Q, Hang H, Zhuang Y, et al. Co-culture with TM4 cells enhances the proliferation and migration of rat adipose-derived mesenchymal stem cells with high stemness. Cytotechnology. 2018;70:1409-1422 pubmed 出版商
Yang S, Liu L, Cao C, Song N, Wang Y, Ma S, et al. USP52 acts as a deubiquitinase and promotes histone chaperone ASF1A stabilization. Nat Commun. 2018;9:1285 pubmed 出版商
Su F, He W, Chen C, Liu M, Liu H, Xue F, et al. The long non-coding RNA FOXD2-AS1 promotes bladder cancer progression and recurrence through a positive feedback loop with Akt and E2F1. Cell Death Dis. 2018;9:233 pubmed 出版商
Xie X, Wang X, Liao W, Fei R, Wu N, Cong X, et al. MYL6B, a myosin light chain, promotes MDM2-mediated p53 degradation and drives HCC development. J Exp Clin Cancer Res. 2018;37:28 pubmed 出版商
Zhang W, Yao F, Zhang H, Li N, Zou X, Sui L, et al. The Potential Roles of the Apoptosis-Related Protein PDRG1 in Diapause Embryo Restarting of Artemia sinica. Int J Mol Sci. 2018;19: pubmed 出版商
Qiu W, Xia X, Qiu Z, Guo M, Yang Z. RasGRP3 controls cell proliferation and migration in papillary thyroid cancer by regulating the Akt-MDM2 pathway. Gene. 2017;633:35-41 pubmed 出版商
Wang L, Song G, Zhang X, Feng T, Pan J, Chen W, et al. PADI2-Mediated Citrullination Promotes Prostate Cancer Progression. Cancer Res. 2017;77:5755-5768 pubmed 出版商
Xue C, Wang C, Sun Y, Meng Q, Liu Z, Huo X, et al. Targeting P-glycoprotein function, p53 and energy metabolism: Combination of metformin and 2-deoxyglucose reverses the multidrug resistance of MCF-7/Dox cells to doxorubicin. Oncotarget. 2017;8:8622-8632 pubmed 出版商
Chang T, Wang S, Chen L, Shih Y, Chang L, Liu S, et al. Regulation of the Abundance of Kaposi's Sarcoma-Associated Herpesvirus ORF50 Protein by Oncoprotein MDM2. PLoS Pathog. 2016;12:e1005918 pubmed 出版商
Wang Y, Chen C, Pan Q, Wu Y, Zhao J, Jiang S, et al. Decreased TPD52 expression is associated with poor prognosis in primary hepatocellular carcinoma. Oncotarget. 2016;7:6323-34 pubmed 出版商
Jin Y, Cao B, Zhang M, Zhan Q, Herman J, Yu M, et al. RASSF10 suppresses hepatocellular carcinoma growth by activating P53 signaling and methylation of RASSF10 is a docetaxel resistant marker. Genes Cancer. 2015;6:231-40 pubmed
图像
图像 1 :
武汉三鹰 19058-1-AP 图像 1
The MDM2 antibody from Proteintech is a rabbit polyclonal antibody to a peptide of human MDM2. This antibody recognizes human,mouse,rat antigen. The MDM2 antibody has been validated for the following applications: WB, ELISA analysis.
产品信息
目录号 :
19058-1-AP
AntigenName :
鼠双微基因2
Package :
150UL
价格 :
299美元
Exsists20ul :
20ul trial size available
FullName :
鼠双微基因2 p53结合蛋白同系物(小鼠)
免疫原 :
多肽
物种 :
artemia sinica, human, mouse, rat
宿主 :
IsConjugated :
未共轭
AntigenSpecies :
人类
应用 :
免疫印迹, 免疫沉淀, 免疫组化, IF, COIP, 酶联免疫吸附测定
Clonlity :
多克隆
抗体亚型 :
IgG
同义词 :
Double minute 2 protein, hdm2, HDMX, MDM2, Oncoprotein Mdm2, p53 binding protein Mdm2
PrimaryOrSecondary :
Primary
抗体缓冲液 :
PBS含0.1%叠氮化钠和50% 甘油pH值7.3
GenBank登录号 :
NM_002392
类别 :
Apoptosis;Binding Proteins;Cell Cycle;Cytoskeleton/Scaffold Proteins;Membrane Proteins;Metabolism;Oncogene(s) and Tumor Suppressor(s);
PurifyMethod :
抗原亲和纯化
NewAb :
False
IsSellable :
True
Feature :
siRNA
AppTiter :
免疫印迹1:1000;
更多信息或购买 :
公司信息
武汉三鹰
武汉市洪山区关山二路关东科技园7-4#,402室
Service@ptglab.com
http://www.ptgcn.com
4006 900 926, 027-87531629 / 027-87531627
公司总部: 美国
Proteintech Group致力于开发针对所有人类蛋白的抗体,我们将这项计划命名为人类抗体组计划。Proteintech Group在科研领域享有良好声誉, 迄今已生产出针对10,000种不同人类蛋白的10,000种抗体。同时,Proteintech Group也提供多种客户订单服务:克隆,表达,多肽合成,多抗及单抗生产,以满足您的不同需求。

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